Presentation Information

5:35 PM - 5:50 PM JST(8:35 AM - 8:50 AM UTC)

[1D23]Mechanistic Insights into Temperature-Induced Monoclonal Antibody Aggregation

*Vinodya Karunadhika^1,2,3, Nimish Pradhan^1,2,3, Annmaree Warrender⁶, Dharmini Mehta^2,3, Heidi Elmer Bodnar^2,3, Thilini Thrimawithana¹, Sally Gras^3,4, Durga Dharmadana^1,3, Celine Valery^1,3,5 (1. RMIT University (Australia), 2. CSL Innovation Pty Ltd (Australia), 3. The ARC Digital Bioprocess Development Hub (Australia), 4. University of Melbourne (Australia), 5. UNSW Sydney (Australia), 6. ANSTO Australian Synchrotron (Australia))

Keywords:

Monoclonal Antibody Formulations,High Concentration,Aggregation,Conformational Stability,Colloidal Stability

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