The 140th Annual Meeting of the Pharmaceutical Society of Japan (Kyoto)
Advanced Search

Session Details

Oral Presentation(A) Organic Chemistry

[26L-pm]生体関連分子②

Thu. Mar 26, 2020 4:09 PM - 6:09 PM JST
Thu. Mar 26, 2020 7:09 AM - 9:09 AM UTC
[Room L] Room C-1 1F
Chair: Yoshiyuki Hari, Noriko Tarashima
4:09 PM - 4:21 PM JST(7:09 AM - 7:21 AM UTC)

[26L-pm12]Synthetic studies for prodrug type oligonucleotide medicines bearing bio-cleavable protecting groups

○Akira Ono1, Tomoki Mikami1, Kaito Suzuki1, Kyouji Horikawa1, Kazuma Terasawa1, Takayuki Ota1, Koudai Nakamura1, Hisao Saneyoshi2 (1. Department of Material & Life Chemistry, Faculty of Engineering, Kanagawa University, 2. School of Medicine, Shiga University of Medical Science)
4:21 PM - 4:33 PM JST(7:21 AM - 7:33 AM UTC)

[26L-pm13S]Synthesis and evaluation of oligodeoxynucleotides containing glycol nucleic acid with 9-aminoethoxyphenoxazine

○Tomoki Matsumura1, Yuki Kishimoto1, Akane Fujii1, Natsumi Nozaki1, Ryohei Yamaji1, Osamu Nakagawa1, Satoshi Obika1 (1. Grad. Sch. Pharm. Sci., Osaka Univ.)
4:33 PM - 4:45 PM JST(7:33 AM - 7:45 AM UTC)

[26L-pm14S]Synthesis and biophysical properties of 5'-dimethyl-DNA (5'-diMe-DNA)

○Go Kato1, Md Ariful Islam1, Tokuyuki Yoshida1,2, Takao Inoue1,2, Takao Yamaguchi1, Satoshi Obika1 (1. Grad. Sch. Pham. Sci., Osaka Univ., 2. NIHS)
4:45 PM - 4:57 PM JST(7:45 AM - 7:57 AM UTC)

[26L-pm15S]Synthesis and biophysical properties of 5'-cyclopropylene DNA

○Takaya Sugiura1, Takaki Habuchi2, Kazuki Asada2, Takao Yamaguchi2, Satoshi Obika2 (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ.)
4:57 PM - 5:09 PM JST(7:57 AM - 8:09 AM UTC)

[26L-pm16S]Synthesis and properties of 4',5'-bridged nucleic acid (4',5'-BNA) : Restriction of torsion angle γ

○Chika Yamamoto1, Masahiko Horiba2, Hiroshi Aoyama2, Takao Yamaguchi2, Satoshi Obika2 (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ.)
5:09 PM - 5:21 PM JST(8:09 AM - 8:21 AM UTC)

[26L-pm17]RNA Synthesis by Chemical Ligation for mRNA Therapeutics

○Yasuaki Kimura1, Kosuke Nakamoto1, Genichiro Tsuji1,2, Fumiaki Tomoike1,3, Kenji Harada4, Junichiro Yamamoto4, Fumikazu Shinohara4, Hiroshi Abe1,5 (1. Grad. Sch. Sci., Nagoya Univ., 2. NIHS, 3. Gakushuin Univ., 4. Kyowa Kirin, 5. JST-CREST)
5:21 PM - 5:33 PM JST(8:21 AM - 8:33 AM UTC)

[26L-pm18S]Development of phosphorofluoridate prodrugs

○Yuki Yoshida1, Ti Zheng1, Daichi Fushihara1, Yushi Nimi1, Kosuke Nakamoto1, Fumitaka Hashiya1, Yasuaki Kimura1, Takako Hiyoshi2, Yuriko Saiki2, Akira Horii2, Tetsuro Suzuki3, Yuko Murakami4, Hiroshi Abe1,5,6 (1. Grad. Sch. Sci., Nagoya Univ., 2. Grad. Sch. Med., Tohoku Univ., 3. Hamamatsu Univ. Sch of Med., 4. Sch. Biosci., Tokyo Univ. of Tech., 5. RIKEN, 6. JST CREST)
5:33 PM - 5:45 PM JST(8:33 AM - 8:45 AM UTC)

[26L-pm19S]Develop an artificial nucleoside recognizable 5mCG base pair for expansion of triplex forming trace

○Ryotaro Notomi1, Yosuke Taniguchi1, Takayuki Osuki1, Sasaki Shigeki1 (1. Grad. Sch. Pharm. Sci., Kyushu Univ.)
5:45 PM - 5:57 PM JST(8:45 AM - 8:57 AM UTC)

[26L-pm20S]Site-specific and efficient acetylation of the 2'-OH of RNA by the reactive oligonucleotide

○Natsu Miyamoto1, Yukiko Abe1, Kentaro Kitazaki1, Hayate Takasaki1, Yosuke Taniguchi1, Shigeki Sasaki1 (1. Grad.Sch.Pharm.Sci., Kyushu Univ.)
5:57 PM - 6:09 PM JST(8:57 AM - 9:09 AM UTC)

[26L-pm21S]Synthesis and evaluation of deazapurine nucleotide analogue for the DNA sequencing including the 8-oxo-2'-deoxyguanosine.

○Yusuke Nagata1, Yosuke Taniguchi1, Ikuko Sagara1, Yoshiya Kikukawa1, Shigeki Sasaki1 (1. Graduate School of Pharmaceutical Science, Kyushu University)
Back to Category List