The 140th Annual Meeting of the Pharmaceutical Society of Japan (Kyoto)
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Session Details

Oral Presentation(A) Organic Chemistry

[26M-pm]ケミカルバイオロジー①

Thu. Mar 26, 2020 1:45 PM - 3:45 PM JST
Thu. Mar 26, 2020 4:45 AM - 6:45 AM UTC
[Room M] Room C-2 1F
Chair: Naoya Shindo, Tasuku Hirayama
1:45 PM - 1:57 PM JST(4:45 AM - 4:57 AM UTC)

[26M-pm01S]Novel method to detect reactive acyl glucuronide metabolites with trapping reagents

○Chikako Shibazaki1, Kyoko Takahashi1, Shigeo Nakamura2, Tomoyuki Ohe1, Tadahiko Mashino1 (1. Faculty of Pharmacy, Keio University, 2. Nippon Medical School)
1:57 PM - 2:09 PM JST(4:57 AM - 5:09 AM UTC)

[26M-pm02S]Squalene as a novel feedforward regulator of squalene monooxygenase stability

○Hiromasa Yoshioka1, Hudson W. Coates2, Ngee Kiat Chua2, Yuichi Hashimoto1, Andrew J. Brown2, Kenji Ogane1,3 (1. IQB, UTokyo, 2. BABS, UNSW, 3. RIKEN)
2:09 PM - 2:21 PM JST(5:09 AM - 5:21 AM UTC)

[26M-pm03S]Design, synthesis, and evaluation of photo-crosslinking HMG-CoA reductase degrader, SR12813

○Yosuke Toyota1, Hiromasa Yoshioka1, Ikuya Sagimori1, Yuichi Hashimoto2, Kenji Ohgane2 (1. Grad. Sch. Pharm. Sci., Tokyo Univ., 2. IQB, the Univ. of Tokyo)
2:21 PM - 2:33 PM JST(5:21 AM - 5:33 AM UTC)

[26M-pm04S]Development of activatable Raman imaging probes for simultaneous detection of multiple enzyme activity

○Hiroyoshi Fujioka1, Mako Kamiya2, Jingwen Shou3, Takanori Iino3, Yasuyuki Ozeki3, Yasuteru Urano1,2,4 (1. Grad. Sch. Pharm. Sci., Tokyo Univ., 2. Grad. Sch. Eng. Sci., Tokyo Univ., 3. Grad. Sch. Med. Sci., Tokyo Univ., 4. CREST, AMED)
2:33 PM - 2:45 PM JST(5:33 AM - 5:45 AM UTC)

[26M-pm05]Dual Raman imaging in living cells with deuterated alkyne

○Syusuke Egoshi1,2, Kosuke Dodo1,2,3, Kenji Ohgane1, Mikiko Sodeoka1,2,3 (1. RIKEN CPR, 2. JST-CREST, 3. RIKEN CSRS)
2:45 PM - 2:57 PM JST(5:45 AM - 5:57 AM UTC)

[26M-pm06]Affinity purification using solid-supported metal complex for biomolecules

○Shuhei Nakao1,2, Kenji Hayamizu1,2, Kenji Ohgane1,2, Miwako Asanuma1,2, Kosuke Dodo1,2, Mikiko Sodeoka1,2 (1. RIKEN, 2. AMED CREST)
2:57 PM - 3:09 PM JST(5:57 AM - 6:09 AM UTC)

[26M-pm07S]Development of novel histone acetylation catalyst system in living cells

○Yuki Yamanashi1, Yusuke Fujiwara1, Yuko Sato2, Hiroshi Kimura2, Kenzo Yamatsugu1, Shigehiro Kawashima1, Motomu Kanai1 (1. Grad. Sch. Pharm. Sci., The Univ. of Tokyo, 2. Inst. of Innovative Research, Tokyo Inst. of Tech.)
3:09 PM - 3:21 PM JST(6:09 AM - 6:21 AM UTC)

[26M-pm08S]Development of histone acylation catalyst with divergent residue selectivity

○Tamiko Nozaki1, Kayo Hanada1, Kenzo Yamatsugu1, Shigehiro Kawashima1, Motomu Kanai1 (1. Grad. Sch. Pharm. Sci, The Univ. of Tokyo)
3:21 PM - 3:33 PM JST(6:21 AM - 6:33 AM UTC)

[26M-pm09S]Development of histone tail selective acylation reaction by chemical catalyst

○Sohei Majima1, Kenzo Yamatsugu1, Shigehiro Kawashima1, Motomu Kanai1 (1. Grad. Sch. Pharm. Sci., The Univ. of Tokyo)
3:33 PM - 3:45 PM JST(6:33 AM - 6:45 AM UTC)

[26M-pm10S]Functional control-oriented non-canonical acylation of protein by small molecule catalyst

○Yugo Roy Kamimura1, Wataru Hamajima1, Kenzo Yamatsugu1, Shigehiro Kawashima1, Motomu Kanai1 (1. Grad. Sch. Pharm. Sci. Univ. of Tokyo)
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