Session Details
[27P-am]物理化学一般①／生体高分子①／生体膜・人工モデル膜①／物理的計測バイオイメージング①／構造生物学①／製剤物理化学①／情報・計算化学①
Fri. Mar 27, 2020 9:00 AM - 11:30 AM JST
Fri. Mar 27, 2020 12:00 AM - 2:30 AM UTC
Fri. Mar 27, 2020 12:00 AM - 2:30 AM UTC
[Room P] Event Hall 1F
[27P-am044S]Multi-nuclear NMR analysis for collapse mechanism of worm-like micelle gel by adding glucose in cetyltrimethylammonium bromide/3-fluorophenylboronic acid system
○Tomoya Yamauchi1, Ryotaro Miki1, Yuya Egawa1, Toshinobu Seki1 (1. Faculty of Pharm. Pharm. Sci., Josai Univ)
[27P-am045]Preparation of PBA-PAMAM/PVA layer-by-layer thin films and release of rifampicin
○Hiroki Midorikawa1, akane yamaguchi1, kenntarou yoshida1, takenori dairaku1, yoshitomo kashiwagi1, tetsuya ono1 (1. Sch. Pharm. Sci., Ohu Univ.)
[27P-am046]Adsorption and release of rose bengal on PBA-PAMAM/PVA multilayer films
○akane yamaguchi1, hiroki midorikawa1, kentaro yoshida1, takenori dairaku1, tetsuya ono1, yoshitomo kashiwagi1 (1. Sch. Pharm. Sci., Ohu Univ.)
[27P-am047]Preparation of layer by layer thin film composed of poly(amidoamine) dendrimer and polyvinylsulfuric acid in the presence and absence of rosebengal.
○Shigehiro Takahashi1, Rena Takahashi1, Sae Motegi1, Iwao Suzuki1 (1. Takasaki University of Health and Welfare School of Pharmacy)
[27P-am048]Interaction mode of the mirtazapine/sulfobutylether-β-cyclodextrin/propylene glycol alginate ternary system by Fragment Molecular Orbital method
○Takayuki Furuishi1, Ayaka Fujisaki1, Kaori Fukuzawa1, Etsuo Yonemochi1 (1. School of Pharmacy and Pharmaceutical Sciences, Hoshi Univ.)
[27P-am049S]Development of novel formulation Using Ionic Liquids for insoluble amino acid BPA
○Kazuki Ishihara1, Sayaka Kawakami1, Nobuyuki Kamegawa3, Ryota Takeuchi3, Hitoshi Hori3,4, Kei Nakai2, Akira Matsumura2, Yuhki Sato1, Makoto Shirakawa1,2 (1. Fukuyama Univ., Pharm., 2. University of Tsukuba, Medicine., 3. Morita Pharmaceutical Ind.,Ltd, 4. Niigata University of Pharmacy and Applied Life Sciences)
[27P-am050]Effects of storage humidity on rebamipide solid dispersion
○Yuta Otsuka1, Yuiko Utsunomiya1, Daiki Umeda2, Yayoi Kawano1, Etsuo Yonemochi2, Takehisa Hanawa1 (1. Fac. Pharm. Sci., Tokyo Univ. Sci., 2. Fac. Pharm Sci., Hoshi Univ.)
[27P-am051]Influence of the charging characteristics of active pharmaceutical ingredients on the mixing of prescription powders
○Kenta Fujinuma1,2, Hokuto Maeda2, Masataka Ito2, Shuji Noguchi2 (1. Pharmaceutical Technology Development Department, Nippon Chemiphar Co., Ltd., 2. Faculty of Pharmaceutical Sciences, Toho University)
[27P-am052S]Antioxidant classification based on ORAC assay to explore an edaravone substitute
○Miwa Takatsuka1, Kenshiro Kobayashi1, Yohsuke Shimada1, Yuta Otsuka1, Satoru Goto1 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science)
[27P-am053S]The influence of diluting solvents against photodegradation suppression of dacarbazine
○Yukiko Nagai1, Jun Miyazaki1 (1. Fac. Pharm. Sci., Hokuriku Univ.)
[27P-am054]Characterization of a novel polymeric prodrug of nalidixic acid synthesized by mechanochemical solid-state polymerization
○Yukinori Yamauchi1, Naoki Doi2, Shin-ichi Kondo2, Yasushi Sasai2, Masayuki Kuzuya3 (1. Department of Pharmaceutical Physical Chemistry, College of Pharmaceutical Sciences, Matsuyama University, 2. Laboratory of Pharmaceutical Physical Chemistry, Gifu Pharmaceutical University, 3. Department of Health & Welfare, Chubu Gakuin University)
[27P-am055]Detection of neutral molecular species desorbed and diffused in the MALDI process using VUV laser ionization
○Tatsuro Shirota1, Takahiro Moriyama1, Kennosuke Hoshina1 (1. Fac. Pharm. Sci., Niigata Univ. Pharmacy & Appl. Life Sciences)
[27P-am056S]NMR analysis of the interaction of PPARγ/RXRα heterodimer
○Shunsuke Sakaguchi1, Takuya Yoshida1, Kazuki Kawahara1, Tadayasu Ohkubo1 (1. Grad. Sch. Pharm. Sci., Osaka Univ.)
[27P-am057S]Elucidation of the mechanism of Tau self-aggregation inhibition by the Fab antibody.
○Tomohiro Tsuchida1, Takahiro Tsuchiya1, Yasuko In1, Katsuhiko Minoura1, Taizo Taniguchi2, Koji Tomoo1 (1. Osaka University of Pharmaceutical Sciences, 2. Pharma Crea Kobe)
[27P-am058]Evaluation of conformational equilibrium of ascidiacyclamide using NMR spectroscopy
○Akiko Asano1, Katsuhiko Minoura1, Takeshi Yamada1, Mitsunobu Doi1 (1. Osaka Univ. Pharm. Sci.)
[27P-am059]Single crystal preparation screening and X-ray crystal structure analysis of multi-component cocrystals
○Katsuhiro Kobayashi1, Akiko Egami1, Takeshi Kawabe1, Tetsuya Araki1, Motomu Ohara1 (1. Analytical & Quality Evaluation Research Laboratories)
[27P-am060]Porphyrins as DNA Topoisomerase I Inhibitors
○Hiroki Munakata1, Mizuki Kitaoka1, Mai Otomo1 (1. Facu. of Pharm. Sci., Hokuriku Univ.)
[27P-am061]A study of cellular accumulation and in vitro and in vivo efficacy of fluorine-substituted tetrazolato-bridged dinuclear platinum(II) complexes on mouse colorectal cancer
○Masako Uemura1, Keiichi Hiramoto1, Hiroki Yoneyama2, Yoshihide Usami2, Shinya Harusawa2, Seiji Komeda1 (1. Fac. Pharm. Sci., Suzuka Univ. Med. Sci., 2. Osaka Univ. Pharm. Sci.)
[27P-am062]Alteration of pH-dependence for coiled-coil assembly property by introduction of acidic amino acid residues into the hydrophobic interface
○Koichi Kato1,2, Tomoki Nakayoshi2, Eiji Kurimoto2, Akifumi Oda2,3 (1. Col. of Pharm, Kinjo Gakuin Univ., 2. Facul. of Pharm, Meijo Univ., 3. Inst. for Prot. Res., Osaka Univ.)
[27P-am063S]Elicidation of Lipid Peroxidation Mechanism in Lipid Membrane
○Hideto Naka1, Yuta Matsuoka1,2,3, Ken-ichi Yamada1,2,3 (1. Sch. Pham. Sci., Kyushu Univ, 2. Grad. Sch. Pham. Sci., Kyushu Univ, 3. AMED-CREST)
[27P-am064]Structural characteristics of Orn-free Gramicidin S analogue
○Mitsunobu Doi1, Shiori Matsuoka1, Chisato Minami1, Takuma Kato1, Akiko Asano1 (1. Osaka Univ. Pharm. Sci.)
[27P-am065S]Inhibitory activity of the specific binding peptide against P-glycoprotein CmABCB1 in nanodisc
○Yue Chen1, Dongqing Pan1, Hayakazu Tsutsui1, Hiroaki Suga2, Hiroaki Kato1,3 (1. Graduate School of Pharmaceutical Sciences, Kyoto University, 2. School of Science, The University of Tokyo, 3. RIKEN SPring-8 Center)
[27P-am066S]Phosphatidylethanolamine enhances fibril formation by the amyloidogenic N-terminal fragment of apolipoprotein A-I
○Naoko Kurimitsu1, Chiharu Mizuguchi1, Kaho Fujita1, Sayaka Horiuchi1, Takashi Ohgita1, Toshinori Shimanouchi2, Hiroyuki Saito1 (1. Kyoto Pharmaceutical Univ., 2. Grad. Sch. Environmental and Life Science, Okayama Univ.)
[27P-am067S]Enhancement of penetration ability of arginine peptide by polyproline Ⅱ helix structure
○Saki Matsui1, Keisuke Okada1, Misaki Takeuchi1, Takashi Ohgita1, Yuki Takechi-Haraya2, Kazuchika Nishitsuji3, Kenji Uchimura4, Koki Hasegawa1, Kumiko Sakai-Kato5, Kenichi Akaji1, Hiroyuki Saito1 (1. Kyoto Pharmaceutical University, 2. National Institute of Health Sciences, 3. Wakayama Medical University, 4. CNRS, 5. Kitasato University)
[27P-am068S]Influences of carbamoylation on the structural properties and amyloid fibril formation of human serum amyloid A
○Tomoya Ujino1, Risa Kojima1, Toshiyuki Yamada2, Masafumi Tanaka1, Hirokazu Nakayama1 (1. Kobe Pharm. Univ., 2. jichi Med. Univ.)
[27P-am069]Analysis of nuclear localization signal of transcription factor GATA
○Wakana Omoto1, Jun Kuwahara1 (1. Fac. Pharm. Sci., Doshisha Women's Univ)
[27P-am070]Zinc finger-importin interaction in nuclear transport of transcription factor
○Jun Kuwahara1, Kanami Nakamura1, Megumi Murakami1 (1. Fac. Pharm. Sci., Doshisha Women's Univ)
[27P-am071]Langmuir monolayer of semifluorinated alcohol and cholesterol
○Hiromichi Nakahara1, Muneaki Minamisono2, Osamu Shibata2 (1. Daiichi Univ. Pharm., 2. Nagasaki Intl.Univ.)
[27P-am072]Effects of lipid composition in cationic liposomes on suppression of mast cell activation
○Yoshikazu Inoh1, Takuya Hirose1, Asami Yokoi1, Satoru Yokawa1, Tadahide Furuno1 (1. Sch. Pharm., Aichi Gakuin Univ.)
[27P-am073]Single–pair FRET measurement of transmembrane helices -Influences of amino acid sequences and lipid compositions on GXXXG–driven helix associations-
Takayuki Morise1, ○Yoshiaki Yano1, Katsumi Matsuzaki1 (1. Grad.Sch.Pharm.Sci., Kyoto Univ.)
[27P-am074S]Effect of ganglioside-containing liposomes for toxemia by Clostridium perfringens alpha toxin
○Taishi Hibino1, Masaki Hasegawa1, Yuki Kaya1, Takuya Yada1, Atsushi Yokotani1, Naoki Hayashi1, Go Kamoshida1, Masataka Oda1 (1. Dept. Microbiol. Infect. Ctrl. Sci., Kyoto Pharm. Univ.)
[27P-am075S]Development of fluorescence imaging probes targeting α-synuclein aggregates in Lewy body disease
○Takuji Ide1, Hiroyuki Watanabe1, Sho Kaide1, Shimpei Iikuni1, Yoichi Shimizu1,2, Masato Hasegawa3, Kyoko Itoh4, Masahiro Ono1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. Kyoto University Hospital, 3. Tokyo Metropolitan Institute of Medical Science, 4. Kyoto Prefectural University of Medicine)
[27P-am076S]Fluorescence imaging of lipid peroxidation in ferroptosis-induced cells
○Yuma Saimoto1, Daiki Kusakabe2, Yuta Matsuoka1,2,3, Ken-ichi Yamada1,2,3 (1. Sch. Pharm. Sci., kyushu Univ., 2. Grad. Sch. Pharm. Sci., kyushu Univ., 3. AMED-CREST)
[27P-am077S]Development of poly[oligo(ethylene glycol) methyl ether methacrylate] conjugated with indocyanine green for fluorescence tumor imaging
○Haruka Miura1, Kohei Sano1, Toshihide Yamasaki1, Masayuki Munekane1, Kazuki Sawada2, Daniel Citterio2, Yuki Hiruta2, Takahiro Mukai1 (1. Kobe Pharm. Univ., 2. Keio Univ.)
[27P-am078]Synthesis of polymorphic semiconductor nanocrystals to investigate shape-dependent uptake efficiency
○Hinako Uno1, Taturou Doi1, Minkyo Jung2,3, Satoka Wada1, Chan-Gi Pack2,3, Fumihiko Fujii1 (1. Pharm. Sci., Kobegakuin Univ., 2. Asan Inst. for Life Sci., Asan Medical Center, Korea, 3. Univ. of Ulsan Coll. of Medicine, Korea)
[27P-am079]Structural change of tryptophan residue upon UV irradiation
○Noriyoshi Manabe1, Kenji Hoshi1, Shiho Ohno1, Yoshiki Yamaguchi1 (1. Fac. Pharm. Sci., Tohoku Med. Pharm. Univ.)
[27P-am080S]Affinity-labeling of the poly-specific substrate binding site in P-glycoprotein, CmABCB1
○Kei Odashima1, Dongqing Pan1, Sorachi Miwa1, Ryo Mizunuma1, Hiroshi Takikawa1, Kiyosei Takasu1, Hiroaki Kato1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. RIKEN SPring-8 Center)
[27P-am081S]Functional investigation of transmembrane helix 4 of thermophilic P-glycoprotein CmABCB1
○Ryo Mizunuma1, Yoshiki Inoue1, Keita Matsuoka1, Dongqing Pan1, Toru Nakatsu1,2, Hiroaki Kato1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. RIKEN Harima Institute at SPring-8)
[27P-am082]By using high-pressure NMR study, the character of hydration-water interacting to protein with its conformational fluctuation.
○Soichiro Kitazawa1, Takuro Wakamoto2, Ryo Kitahara1,2 (1. College of Pharmaceutical Sciences, Ritsumeikan Univ., 2. Graduate School of Life Sciences,Ritsumeikan Univ.)
[27P-am083]Cyclization mechanism catalyzed by DcsG essential for D-cycloserine biosynthesis
○Yasuyuki Matoba1, Uda Narutoshi2, Kudo Mako2, Sugiyama Masanori2 (1. Facul. Pharm., Yasuda Women's Univ., 2. Grad. Sch. Biomed. Health Sci., Hiroshima Univ.)
[27P-am084S]Investigation of ionization potential of pharmaceutical compoundsI ~Molecular orbital and Raman spectrum approach~
○Maki Hoga1, Yusuke Hattori1, Makoto Otsuka1 (1. Musashino Univ.)
[27P-am085S]Exploring Cocrystals of Artemisinin to improve its physical property
○Soichiro Miura1, Ryotaro Koyama1, Naoya Tuno1, Kazuhiko Takatori1, Varin Titapiwatanakun2, Toshiro Fukami1 (1. Meiji Pharm Univ., 2. Pharm. Sci., Chulalongkorn Univ.)
[27P-am086S]Development of temperature-sensitive liposome targeting CD44 expressed cell
○Ayaka Innami1, Tsubasa Yamanouchi1, Maitani yoshie1, Kanazawa Hideko1 (1. Grad. Sch. Pharm. Sci., Keio Univ.)
[27P-am087S]Development of LAT1-targeting liposomes using temperature-responsive polymer
○Kanon Arimura1, Kei Fujieda2, Minami Matsuura2, souta yamada1, Kenichi Nagase1, Hideko Kanazawa1 (1. Pharm.Sci., Keio Univ., 2. Grad. Sch. Pharm. Sci., Keio Univ.)
[27P-am088S]Dual temperature-and pH-responsive polymeric micelle for cancer therapy
○Keima Aihara1, Sota Yamada1, Kenichi Nagase1, Hideko Kanazawa1 (1. Pharm. Sci., Keio Univ.)
[27P-am089S]QSAR and docking study on prediction of bioactivity for mu opioid receptor ligands.
○Materu Yuyama1, Yuki Kadowaki1, Yumiko Arai1, Yuuki Akutsu1, Hiroto Tamazawa1, Takayuki Kanaya1, Masahiko Hunada3, Masaaki Kurihara1,2 (1. IUHW, 2. NIHS, 3. NCNP)
[27P-am090S]Construction of risk prediction method for anticholinergic effect using QSAR.
○Yuki Kadowaki1, Materu Yuyama1, Yumiko Arai1, Yuuki Akutsu1, Hiroto Tamazawa1, Natsumi Iiyama1, Ayako Keino1, Yurina Hiraoka1, Takeshi Ito1, Takayuki Kanaya1, Yasuyuki Momose1, Masaaki Kurihara1,2 (1. IUHW, 2. NIHS)
[27P-am091]Molecular modeling study of the complex between molecules of natural product origin and Keap1
○Toshiyuki Hata1, Shoji Maehara1, Masatoshi Ohnishi1, Atsuko Inoue1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama Univ.)
[27P-am092S]DFT calculations to evaluate weak interactions between crystalline sponge and analyte in laser desorption ionization
○Ayane Yano1, Yukako Hayashi1, Kazuaki Ohara1, Kentaro Yamaguchi1 (1. Fac. Pharm. Sci. Kagawa Campus, Tokushima Bunri Univ.)
[27P-am093S]Computational studies on the phosphate-catalyzed mechanisms for the succinimide formation of aspartic acid residues via iminol tautomer
○Tomoki Nakayoshi1,2, Koichi Kato1,3, Ohgi Takahashi4, Eiji Kurimoto1, Akifumi Oda1,2,5 (1. Graduate School of Pharmacy, Meijo University, 2. Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 3. Department of Pharmacy, Kinjo Gakuin University, 4. Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 5. Institute for Protein Research, Osaka University)
[27P-am094]Verifications of protein/ligand interaction calculation using probe-based QM modeling
○Daichi Hayakawa1, Yurie Watanabe1, Hiroaki Gouda1 (1. School. Pharm., Showa Univ.)
[27P-am095]FMO drug discovery for the design of ERβ selective ligands
○Kaori Fukuzawa1, Yuya Seki1, Mai Uemura1, Tsukasa Kato1, Satoshi Anzaki2, Shigenori Tanaka2, Takayuki Furuishi1, Etsuo Yonemochi1 (1. Sch. Pharm., Hoshi Univ., 2. Grad. Sch. System Info., Kobe Univ. )
[27P-am096]Development of novel organic fluorescent dyes and evaluation of theri aggregation-induced emission enhancement (AIEE) properties ②
○Natsuki Kuwahara1, Masayori Hagimori2, Yasuhisa Nishimura3, Keitaro Tanaka1, Tatsusada Yoshida1 (1. Faculty of Pharm. Sci., Nagasaki Int. Univ., 2. Grad. Sch. Biomed. Sci., Nagasaki Univ., 3. Faculty of Engineering, Nagasaki Univ.)
[27P-am097]Conformational comparison between hemoglobin A and hemoglobin S by molecular dynamics simulations
○Shin-ichi Fujiwara1, Takashi Amisaki1 (1. Fac. Med., Tottori Univ.)
[27P-am098]Filtering conditions for virtual screening using hydration site analysis
○Tomoki Yoshida1, Shuichi Hirono1 (1. Sch. Pharm., Kitasato Univ.)
[27P-am099]Ligand binding affinity calculations for tRNA-ligase and its mutants using molecular dynamics simulations
○Yoshiharu Mori1, Mayuko Takeda-Shitaka1 (1. Sch. of Pharm., Kitasato Univ.)
[27P-am100S]Effect of electrostatic potential on protein crystallization
○YAN GUO1, LIANG QU1, NORITAKA NISHIDA1, TYUJI HOSHINO1 (1. Department of Physical Chemistry Graduate School of Pharmaceutical Sciences Chiba University)
[27P-am101S]In silico drug design of the DAPK1 inhibitor with improvement of water solubility and inhibitory ability
○Ayaka Tanabe1, Jun Miyazaki1, Kazuhiro Fujimoto1,2 (1. Fac. Pharm. Sci., Hokuriku Univ., 2. WPI-ITbM, Nagoya Univ.)
[27P-am102S]Computational study on relationships between main chain conformations and a carbonatecatalyzed mechanism of asparagine deamidation
○Kaho Miura1, Koichi Kato1,2, Tomoki Nakayoshi2, Eiji Kurimoto2, Akifumi Oda2,3, Kikuo Tsukamto1 (1. Col. of Pharm.,Kinjo Gakuin Univ., 2. Facul of Pharm.,Meijo Univ., 3. Inst for Prot. Res., Osaka Univ.)
[27P-am103]Analysis of ribitol conformation by computational chemistry
○shiho ohno1, noriyoshi manabe1, yoshiki yamaguchi1 (1. Tohoku medical and pharmaceutical university Pharmaceutical physical chemistry)