Session Details
[27P-am]生体分子③／細胞の構造と機能③／生体の高次構造①／生体分子④／細胞の構造と機能④
Fri. Mar 27, 2020 9:00 AM - 11:30 AM JST
Fri. Mar 27, 2020 12:00 AM - 2:30 AM UTC
Fri. Mar 27, 2020 12:00 AM - 2:30 AM UTC
[Room P] Event Hall 1F
[27P-am165S]Stimulatory Release of Hepatic Triacylglyceride Lipase by Metformin -Involvement of Protein Synthesis-
○Shizuka Tanabe1, Tomoyasu Hujii1, Jun Kamisikiryou1, Tetsuo Morita1 (1. Dept.Biochem.Fac.Pharm Sci.,Fukuyama Univ.)
[27P-am166S]Function of leukotrienes in adipocytes
○Saki Uno1, Kyouhei Kuroda1, Toko Maehara1, Ko Fujimori1 (1. Osaka Univ. Pharm. Sci.)
[27P-am167S]Effects of the ichthyosis-causative mutations in the fatty acid ω-hydroxylaze gene CYP4F22 on the production of the skin barrier lipid acylceramide
○Tomohiro Nohara1, Yusuke Ohno1, Akio Kihara1 (1. Fac. Pharm. Sci, Hokkaido Univ.)
[27P-am168S]Elucidation of FGFR4-signal transduction mechanism through FGFR4-FGFR1 hetero dimer
○Du Yan1, Chika Sakasegawa2, Hiroki Hayashida2, Yu Yaguchi2, Shun Amemiya1, Takashi Sato3, Hiroshi Morioka3, Yoshihiro Kobashigawa3 (1. Grad. Sch. Pharm. Sci. Kumamoto Univ., 2. Sch. Pharm. Kumamoto. Univ., 3. Fac. Life Sci. Kumamoto. Univ.)
[27P-am169S]A study of herbal medicine extract component to promote collagen fibril formation
○Yuta Hiratsuka1,2, Kaito Furuya1,2, Mayu Teruo1,2, Chikako Kuzu1,2, Tetsuro Yumoto1,2, Kinni You3, Fumiaki Sato1,2 (1. Dept. of Anal. Pathophysical,Hoshi univ., 2. Dept. of Biomodec. Pharmaco,Hoshi univ., 3. TOKIWA PHYTOCHEMICAL CO.,LTD.)
[27P-am170S]Cytotoxic effect of cytarabine in prolyl oligopeptidase knockout cells
○Ryota Nishiuchi1, Mika Bando1, Chiaki Isaka1, Yuki Huruta1, Yui Yamada1, Satoshi Tanaka1, Minoru Sakaguchi1 (1. Osaka Univ. Pharm. Sci.)
[27P-am171]Crystal structure analysis of human erythrocyte band3 protein / substrate conjugate
○tomoki nagamine1, Hiroyuki Kuma1, Hinako Hatae1 (1. Pharm.sci.,Nagasaki international unib)
[27P-am172S]Synthesis and evaluation of novel TGR5 agonists by bile acid modification
○Daisuke Hino1, Go Masuda1, Ayasa Konishi1, Masaharu Murakami1, Yuki Fukuzumi1, Yukiko Yamashita1, Yusuke Iguchi1, Mizuho Une1 (1. Sch. Pharm. Sci., Hiroshima International Univ.)
[27P-am173S]Involvement of cytochrome P450 in the hydroxylation of lithocholic acid
○Riku Matsuyama1, Kazuki Yoshioka1, Yu Nakano1, Takako Moriuchi1, Shoma Yamamura1, Yukiko Yamashita1, Yusuke Iguchi1, Mizuho Une1 (1. Sch. Pharm. Sci., Hiroshima International Univ.)
[27P-am174S]Effects of novel TGR5 agonist on hepatic lipid accumulation and inflammation in dietary obese model mice
○Masashi Hamada1, Ayasa Konishi1, Yukiko Yamashita1, Yusuke Iguchi1, Mizuho Une1 (1. Sch. Pharm. Sci., Hiroshima International Univ.)
[27P-am175S]Effects of novel TGR5 agonists on db/db mice, a rodent model for obesity and type 2 diabetes
○Keiji Okamoto1, Ayasa Konishi1, Yukiko Yamashita1, Yusuke Iguchi1, Mizuho Une1 (1. Sch. Pharm. Sci., Hiroshima International Univ.)
[27P-am176]Methods to evaluate states of liquid-liquid phase separation using proximal biotinylation in saccharomyces cerevisiae
○Shinya Takazaki1, Kaho Arimori1, Tomohide Baba1, Ryota Higa1, Kazuhisa Ota1 (1. Faculty of Pharm. Sci., Nagasaki Itn. Univ.)
[27P-am177S]Expression of peptides inducing liquid-liquid phase separation for searching novel membraneless organelles in saccharomyces cerevisiae
○Tomohide Baba1, Shinya Takazaki1, Kaho Arimori1, Ryota Higa1, Kazuhisa Ota1 (1. Faculty of Pharm. Sci., Nagasaki Itn. Univ.)
[27P-am178S]Control of liquid-liquid phase separation by expression of peptides composed of repetitive sequence of intrinsically disordered region in saccharomyces cerevisiae
○Ryota Higa1, Shinya Takazaki1, Kaho Arimori1, Tomohide Baba1, Kazuhisa Ota1 (1. Faculty of Pharm. Sci., Nagasaki Itn. Univ.)
[27P-am179S]Search for components that improve mitochondrial function in glycyrrhiza uralensis extracts.
○Misaki Sato1, Yumiko Ishibashi1, Shinya Takazaki1, Takuhiro Uto1, Kazuhisa Ota1 (1. Faculty of Pharm. Sci.,Nagasaki Itn.Univ.)
[27P-am180S]Purification of the cell surface CFTR by Halo-tag technology
○Chikako Nakashima1, Tomoki Kato1, Tsukasa Okiyoneda1 (1. Grad. Sch. Sci., Kwansei Gakuin Univ.)
[27P-am181S]Reduced protein expression of lysosomal enzyme induced by 1BnTIQ, an endogenous Parkinson's disease-related neurotoxin
○Ayaka Yabuki1, Masatsugu Miyara1,3,2, Kanae Umeda1,4, Natsumi Okada1, Namiko Watanabe1, Shigeru Ohta1,5, Yaichiro Kotake1 (1. Hiroshima Univ., 2. Gifu Pharm. Univ., 3. JSPS Research Fellow PD, 4. JSPS Research Fellow DC, 5. Wakayama Med. Univ.)
[27P-am182S]Evaluation of estrogenic activity of compounds in ginger
○Yuzuki Niwa1, Kentaro Nishi1, Wenqiang Fu1, Shin-ichiro Isobe1, Ryoiti Kiyama1 (1. Fac. life Sci., kyusan. Univ.)
[27P-am183S]Role of reactive sulfur in platelet-derived growth factor-induced vascular smooth muscle cell migration
○Shunichi Ishii1, Mayu Watanabe1, Takashi Ashino1, Satoshi Numazawa1 (1. Sch.Pharm.,Showa Univ)
[27P-am184S]Regulation of expression of reactive sulfur species-producing enzymes by TGF-β1 in cultured vascular endothelial cells
○Musubu Takahashi1, Akane Takahashi1, Tomoya Fujie2, Chika Yamamoto2, Toshiyuki Kaji1 (1. Fac. of Pharm. Sci., Tokyo Univ. of Sci., 2. Fac. of Pharm. Sci., Toho Univ. )
[27P-am185S]Elucidation of hyperosmotic stress response through MALAT1, a long noncoding RNA
○Yoko Ogura1,2, Rena Onoguchi2, Nobuyoshi Akimitsu1,2 (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo, 2. ISC, Univ. of Tokyo)
[27P-am186S]CRBN mutation- independent resistance mechanisms against lenalidomide in multiple myeloma
○Arisu Furukawa1, Takeshi Masuda1,3,4, Hiroto Ohguchi2, Yui Kaneko3, Shingo Ito1,3,4, Sumio Ohtsuki1,3,4 (1. Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. IRDA., Kumamoto Univ., 3. Sch. Pharm., Kumamoto Univ., 4. Grad. Fac. Life Sci., Kumamoto Univ.)
[27P-am187S]Regulation mechanisms of folate metabolizing enzyme ALDH1L1/2 by ubiquitin modification
○Kazuyasu Kanazawa1, Masato Sasaki1, Erika Sato1, Shunto Sagawa1, Ami Takeyama1, Fumie Ito1, Yutaka Tanaka1, Nobuyuki Shibata1 (1. Tohoku Medical and Pharmaceutical University)
[27P-am188S]PDZ-domain may regulate protease activity of HtrA2.
○kosuke tobe1, Momoka Narao1, Kyoichiro Higashi1 (1. Dept of Pharmacy, Meiji Pharm. Univ.)
[27P-am189S]Effects of carthamus tinctorius leaf extract for autophagy on skin cells
○Kentaro Igami1, Kaede Nakashima1, Ami Katsuki1, Toshitsugu Miyazaki1, Hisatomi Ito1 (1. Nagase Beauty Care & CO., Ltd.)
[27P-am190S]Development of a peptidomimetic XIAP inhibitor based on Smac N-terminal peptide
○Saki Seno1, Yuki Yashiro1, Kana Yamaji1, Yuji Kogami2, Atsushi Yoshimori3, Sei-ichi Tanuma4, Ryoko Takasawa1 (1. Facul. Pharm. Sci., Tokyo Univ. Sci., 2. D.D.P. Corporation , 3. ITM, Inc., 4. Research Institute for Science and Technology, Organization for Research Advancement, Tokyo Univ. Sci.)
[27P-am191S]Analysis of human Glyoxalase I inhibition and cell death induction by organobismuth compounds
○Kanako Nakamine1, Miku Azuma1, Manami Inoue1, Shunsuke Natani1, Ryusei Chimori1, Yasunari Mano1, Shuji Yasuike2, Toshiyuki Kaji1, Ryoko Takasawa1 (1. Facul. Pharm. Sci., Tokyo Univ. Sci., 2. School of Pharm., Aichi Gakuin Univ.)
[27P-am192S]Effect of TRP channels for Epithelial Mesenchymal Transformation
○yuuki sugiyama1, toko sakagami1, yosuke nakazawa1, megumi tago1, hiroomi tamura1 (1. Fac. Pharm., Keio Univ.)
[27P-am193S]Function of membrane microvesicles secreted from skin resident bacteria
○Yuki Ohno1, Tomoya Okamoto2, Yoshihisa Nakada2, Yuhko Itoh3, Yukihiro Akao4, Tomohiro Itoh1 (1. Grad. Sch. Bioresources. Mie Univ., 2. Ichimaru Pharcos Co., Ltd, 3. Osaka med col, 4. United Grad. Sch. Drug Discov. Med. Info. Sci., Gifu Univ.)
[27P-am194S]Exploration of regulatory factors for alternative splicing of Alzheimer's disease-associated genes
○Motoaki Yanaizu1, Souta Satoh1, Yoshihiro Kino1, Jun-ichi Satoh1 (1. Meiji Pharm Univ.)
[27P-am195S]Construction and cellular expression of long GGGGCC repeats associated with amyotrophic lateral sclerosis
○Kazunobu Oota1, Minami Kawai1, Yoshihiro Kino1, Jun-ichi Satoh1 (1. Meiji Pharm Univ.)
[27P-am196S]Search for genes involved in RNA foci formation and/or degradation.
○Kai Nishimiya1, Yoshihiro Kino1, Jun-ichi Satou1 (1. Meiji Pharm Univ.)
[27P-am197S]RNA-binding proteins that regulate Alzheimer's disease-associated alternative splicing of CD33
○Yuka Honda1, Motoaki Yanaizu1, Yoshihiro Kino1, Jun-ichi satoh1 (1. Meiji Pharm Univ.)
[27P-am199S]Identification of splicing regulators of IL7R, a risk factor of multiple sclerosis
○Mio Hayama1, Motoaki Yanaizu1, Yoshihiro Kino1, Jun-ichi Satoh1 (1. Meiji Pharm Univ.)
[27P-am200S]Development of In vivo imaging system of gene expression in freely moving mouse
○Aya Chishima1, Harumi Kano1, Akari Ota1, Kanako Nakajima1, Yoshihiro Kikutci1, Ryoga Ito1, Masaki Masaki2, Mitchitaka Ozaki3, Kazuko Hamada1, Toshiyuki Hamada1,3 (1. Department of Pharmaceutical Sciences, International University of Health and Welfare, 2. Graduate school of health sciences, Hokkaido University, 3. Health Innovation & Technology Center, Faculty of Health Sciences, Hokkaido University)
[27P-am201S]The role of L-luciferin on in vivo gene expression rhythm in freely moving mouse
○Kanako Nakajima1, Ryoga Ito1, Yoshihiro Kikuchi1, Harumi Kanou1, Aya Chishima1, Oota Akari1, Masayori Ishikawa2, Mitchitaka Ozaki3, Kazuko Hamada1, Toshiyuki Hamada1,3 (1. Department of Pharmaceutical Sciences,International University of Health and Welfare, 2. Graduate school of health sciences,Hokkaido university,Sapporo,Japan, 3. Health Innovation and Technoligy Center,Faculty of Health Sciences,Hokkaido University)
[27P-am202S]Double recording of clock gene expression in central and peripheral tissues of freely moving mouse
○Ryoga Ito1, Yoshihiro Kikuchi1, Kanako Naka1, Harumi Kanou1, Aya Chishima1, Masayori Ishikawa2, Mitchitaka Ozaki3, Kazuko Hamada1, Toshiyuki Hamada1 (1. Department of Pharmaceutical Sciences, International University of Health and Welfare, 2. Graduate school of health sciences, Hokkaido University, Sapporo, Japan, 3. Health Innovation and Technology Center, Faculty of Health Sciences, Hokkaido University)
[27P-am203S]in vivo recording system of clock gene expression using a photomultipliertube in freely moving mouse
○yoshihiro kikuchi1, kanako nakajima1, harumi kano1, aya chishima1, akari ota1, ryoga ito1, masayori ishikawa2, michitaka ozaki3, kazuko hamata1, toshiyuki hamada1 (1. Department of Pharmaceutical Sciences,International University of Health and Welfare, 2. Graduate school of health sciences,Hokkaido unibersity,Spporo,Japan, 3. Health Innovation&Technology Center,Faculty of Health Sciences,Hokkaido University)
[27P-am204S]The physiological significance of Reelin cleavage in hippocampal layer formation revealed by cleavage-resistant Reelin knock-in mouse
○Tomofumi Shigenobu1, Eisuke Okugawa1, Takao Kohno1, Hisashi Oishi2, Mitsuharu Hattori1 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ., 2. Grad. Sch. Med. Sci., Nagoya City Univ.)
[27P-am205S]Clarification of Reelin secretion mechanism using bioluminescence imaging
○Yousuke Nakao1, Satoru Yokawa2, Takao Kohno1, Takahiro Suzuki3, Mitsuharu Hattori1 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ., 2. Sch. Pharm., Aichi Gakuin Univ. , 3. Sch. Dent., Aichi Gakuin Univ.)
[27P-am206S]Qualitative changes in immune cells by the artificial activation of sensory nerves
○Kensuke Yamashita1, Takashige Kondo1, Yusuke Hamada1, Kenichi Tanaka1, Daisuke Sato1, Masumi Iizuka1, Haruna Shimizu1, Hiroyuki Tezuka2, Akihiro Yamanaka3, Naoko Kuzumaki1, Minoru Narita1 (1. Dept. Pharmacol., Hoshi Univ., 2. Dept. Cell. Functional Analysis, Fujita Health Univ., 3. Dept. Neurosci. Ⅱ, RIEM, Nagoya Univ.)
[27P-am207S]Therapeutic effect of high-level expression of lipoprotein lipase in the liver using an improved adenovirus on metabolism in high-fat diet-fed mice
○Syogo Nishimuta1, Kahori Shimizu1, Yuka Egusa1, Yuri Fukumura1, Tomoyuki Terada1, Fuminori Sakurai2, Hiroyuki Mizuguchi2,3,4,5, Koji Tomita1, Toru Nishinaka1 (1. Pharma., Osaka Ohtani Univ., 2. Grad. Sch. of Pharma. Sci., Osaka Univ., 3. Natl. Inst. of Biomed. Innov. Health Nutr., 4. MEIC, Osaka Univ., 5. OTRI, Osaka Univ.)
[27P-am208S]Effect of high-level expression of type 2 diabetes susceptibility gene on "Zinc finger AN1-type domain" on glucose metabolism
○Hajime Kimura1, Kahori Shimizu1, Kaede Yoshinaga1, Yuya Ogiya1, Tomoyuki Terada1, Fuminori Sakurai2, Hiroyuki Mizuguchi2,3,4,5, Koji Tomita1, Toru Nishinaka1 (1. Pharma., Osaka Ohtani Univ., 2. Grad. Sch. of Pharma. Sci., Osaka Univ., 3. Natl. Inst. of Biomed. Innov. Health Nutr., 4. MEIC, Osaka Univ, 5. OTRI, Osaka Univ)
[27P-am209]Exploratory research on a novel factor enhancing cisplantin-induced anti-tumor effect against bladder cancer cells
○Emiko Yoda1, Satoko Nakayama2, Yasutomo Suzuki2, Yukihiro Kondo2, Shuntaro Hara1 (1. Pharmacy Sch., Showa Univ., 2. Nippon. Med. Sch.)
[27P-am210]Searching for drugs metabolized by PAF-acetylhydrolases
○Ayako Harada1, Yasuhiro Nakamura1, Kazunari Tanigawa1, Ken Karasawa1 (1. Fac. Pharm. Sci., Teikyo Univ.)
[27P-am211]Cholesterol-binding analysis of the extracelluer domain of NPC1L1
○Emiko Nishiyama1, Kaede Fujisawa1, Tomoyasu Fujii1, Tetsuo Morita1, Jun Kamishikiryo1 (1. Faculty of Pharmacy and Pharmaceutial Sciences,Fukuyama University)
[27P-am212]The role of glycosylation in the expression of adenosine deaminase 2 activity
○Moeko Ito1, Yusei Nakae1, Ayami Ono1, Yasuhiro Watanabe1, Sachiko Iwaki-Egawa1 (1. Faculty of Pharmaceutical Science, Hokkaido University of Science)
[27P-am213]Expanding the sugar-modified nucleic acids library for X-SELEX
○Hidekazu Hoshino1, Yuuya Kasahara1,2, Masayasu Kuwahara3, Satoshi Obika1,2 (1. NIBIOHN, 2. Grad. Sch. of Pharm. Sci., Osaka Univ., 3. Grad. Sch. of Integr. Basic Sci., Nihon Univ.)
[27P-am214]Construction of gapmer antisense oligonucleotide design platform
○Yuuya Kasahara1,2, Harumi Yamaguma1, Satoshi Obika1,2 (1. NIBIOHN, 2. Grad. Sch. Pharm. Sci., Osaka Univ.)
[27P-am215]An essential role of proton pumping ATPase in Streptococcus anginosus under acidic conditions
○Mizuki Sekiya1, Kota Murakami1, Miho Kosaka1, Naomi Matsumoto1, Yu Shimoyama2, Taichi Ishikawa2, Kikuko Kawano1, Shio Yano1, Minoru Sasaki2, Mayumi Nakanishi-Matsui1 (1. Sch. of Pharm., Iwate Med. Univ., 2. Sch. of Dent., Iwate Med. Univ.)
[27P-am216]Evidence of sulfhydryl oxidase existing in the stratum corneum
○Yuki Sato1,2, Yuri Okano1, Hitoshi Masaki2 (1. CIEL Co., Ltd., 2. Tokyo University of Technology)
[27P-am217]Effect of metal ions in the regulation of enzyme activity of intracellular phospholipase A1s.
○Naoki Matsumoto1, Yasuhiro Hayashi1, Yoko Nemoto-Sasaki1, Wakako Urayama1, Atsushi Yamashita1 (1. Fac. Pharm. Sci., Teikyo Univ.)
[27P-am218]Substrate specificity analysis of recombinant RNPEPL1
Masaki Kurakane1, Ayaka Kobayashi1, Kazunari Wakana1, ○Atsushi Ohnishi1, Masafumi Tsujimoto1 (1. Pharm. Sci.,Teikyo Heisei Univ.)
[27P-am219]Production of cholinesterase by HuH-7 cells
○Yukiyo Hirata1, Koichi Igarashi1, Haruka Ito1, Hirofumi Inagaki1, Tomoyuki Kawada1 (1. Dep. of Hyg. and Publ. Hlth., Nippon Med. Sch.)
[27P-am220]Introduction effect of RNases from mushroom into HL-60 cells
○hiroko kobayashi1, karin omachi1, ayano ozaki1, kazuki yaita1, naomi motoyoshi1, tadashi itagaki1 (1. Sch.Pharm.,nihon Univ)
[27P-am221]Establishment of sample preparation methods for mevalonate kinase and phosphomevalonate kinase
○Chiyuki Suzuki1, Chiaki Okada1, Teruki Yoshimura1 (1. Grad. Sch. Pharm. Sci., Health Sci. Univ. of Hokkaido.)
[27P-am222]Characterization of serine racemase homolog from hyperthermophile Thermotoga maritima
○Tetsuya Miyamoto1, Yasuaki Saitoh1, Masae Sekine1, Masumi Katane1, Kumiko Sakai-Kato1, Hiroshi Homma1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ.)
[27P-am223]Effect of vesicle transport-related gene mutations on p97 RNAi-induced abnormal accumulation of birefringent organelles in C. elegans intestinal cells
○Hirohisa Shiraishi1, Mayu Yaegashi1, Fumiko Umemura1, Kaho Kato1, Kenji Nishikori1, Takahiro Tanji1, Ayako Ohashi-Kobayashi1 (1. Sch. Pharm., Iwate Med. Univ.)
[27P-am224]Property change of exosomes derived human nerve cell model by amphetamines.
○Takuya Yamashita Yamashita1, kairi Murata1, Fujiwara Jyunpei1, Fumiyo Kasuya1 (1. Faculty of Pharmaceutical Sciences, Kobegakuin University)
[27P-am225]Expression of Opsin receptors in skin
○Hiroyuki Yamamoto1, Saki Andoh1, Aoi Onohara1, Akari Sawayanagi1, Toshiyuki Yamada1 (1. Nihon Pharm. Univ.)
[27P-am226]Autophagy is involved in improvement of mitochondrial function by epalrestat.
○Momoko Yada1, Yuna Oi1, Keisuke Sato1, Ryosuke Tatsunami1 (1. Hokkaido University of Science )
[27P-am227]Effects of autophagy on homocysteine-induced cytotoxicity
○Tsubasa Sugawara1, keisuke sato1, ryosuke tatsunami1 (1. Hokkaido University of Science)
[27P-am228]The mechanism of apoptosis suppression by RasGRP2 in vascular endothelial cells
○Jun-ichi Takino1, Takuma Sato1, Kentaro Nagamine2, Takamitsu Hori1 (1. Fac. of Pharm. Sci., Hiroshima International Univ., 2. Fac. of Clin. Nutr., Hiroshima International Univ.)
[27P-am229]cSBL decreases AKR1B10 expression
○Takeo Tatsuta Tatsuta1, Shigeki Sugawara1, Hosono Masahiro1 (1. Div. of Cell Recog. Study, Tohoku Med. Pharm. Univ.)
[27P-am230]Development of blue ALDH1 fluorescent probes using 8-amino BODIPY
○Atsushi Yagishita1,2, Tasuku Ueno2, Izumi Umeda1, Katsuya Ueno3, Yasuteru Urano2,4,5 (1. Kavli IPMU, U Tokyo, 2. Grad. Sch. Pharm. Sci., Tokyo Univ., 3. Natl. Cancer Ctr., 4. Grad. Sch. Med., Tokyo Univ., 5. AMED-CREST)