The 140th Annual Meeting of the Pharmaceutical Society of Japan (Kyoto)
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Session Details

Poster Presentation(B) Radiochemistry

[27P-pm]放射化学・放射性医薬品②

Fri. Mar 27, 2020 2:00 PM - 4:30 PM JST
Fri. Mar 27, 2020 5:00 AM - 7:30 AM UTC
[Room P] Event Hall 1F
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm181S]Tumor uptake and biodistribution of folate modified Lactosome

○Satoshi Hariu1, Mio Okada1, Ryo Sasaki1, Akira Makino2, Yumi Yamamoto1, Yohei Saitou1, Fumihiko Yamamoto1 (1. Tohoku Med. Pharm. Univ., 2. Fukui Univ. BIRC)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm182S]Evaluation of p38 alpha imaging probe [123/125I]FIC using turpentine oil induced inflammation model mice

○Tomoyuki Hashimoto1, Masahiko Hirata1, Atsuko Takeguchi1, Kaede Hanazono1, Ryuji Kakisaka1, Naofumi Yoshida1, Hiroyuki Watanabe2, Shimpei Iikuni2, Masahiro Ono2, Yoshiro Ohmomo1, Naoya Kondo1, Takashi Temma1 (1. Grad. Sch. Pharm. Sci., Osaka. Univ. of Pharm. Sci, 2. Grad. Sch. Pharm. Sci., Kyoto. Univ)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm183S]SPECT imaging of inflammation with 67Ga-labelled Reactive Black 5 derivative

○Erika Saito1, Tomoshige Ando1, Yasunao Hattori1, Koki Hasegawa1 (1. Kyoto Pharmaceutical University)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm184S]Synthesis and fundamental evaluation of radiogallium-labeled imidazothiadiazole sulfonamide derivative for PET imaging of carbonic anhydrase IX

○Kazuma Nakashima1, Shimpei Iikuni1, Yuya Okada1, Hiroyuki Watanabe1, Yoichi Shimizu1,2, Masahiro Ono1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. Kyoto Univ. Hosp.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm185S]Evaluation of novel 99mTc-hydroxamamide complex based on imidazothiadiazole sulfonamide as imaging probe targeting carbonic anhydrase IX

○Anna Kitano1, Shimpei Iikuni1, Hiroyuki Watanabe1, Yoichi Shimizu1,2, Masahiro Ono1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. Kyoto Univ. Hosp.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm186S]The study of developing technetium-99m(99mTc) high specific activity labeled SPECT imaging drug assessing novel antimicrobial

○Kento Higa1, Tomoya Uehara1, Sotaro Momosaki2, Kohji Abe2, Hiroyuki Suzuki1, Yasushi Arano1 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. SHIONOGI & CO., LTD.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm187S]Rapid and high-yield syntheses of 99mTc-labeled hexavalent probes for in vivo imaging of saturable systems

○Yuka Shimoda1, Yuki Mizuno1, Kohta Kimura1, Satoru Onoe1, Miho Shukuri1, Yasushi Arano2, Hiromichi Akizawa1 (1. Showa Pharamaceutical University, 2. Chiba University)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm188S]Evaluation of a radiolabeled bicyclic RGD peptide as a probe for imaging integrin αvβ3

○Keita Wakamori1, Kondo Naoya1, Masahiko Hirata1, Takashi Temma1 (1. Osaka.univ.of Pharm. Sci.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm189S]Development of nuclear medical imaging probes targeting myelin for diagnosis of multiple sclerosis

○Rinka Maekawa1, Hiroyuki Watanabe1, Shimpei Iikuni1, Yoichi Shimizu1,2, Nagisa Matsuo1, Hisashi Shirakawa1, Syuji Kaneko1, Masahiro Ono1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. Kyoto Univ. Hosp.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm190S]Evaluation of optical isomer (+)-[125/123I]OI5V as a sigma-1 receptor imaging probe.

○Kimika Abe1,2, Maika Takahashi1,2, Takashi Kosaka1,2, Yoji Kitamura1,2, Kazuma Ogawa1,3, Kazuhiro Shiba1,2 (1. Kanazawa University, 2. ASRC Kanazawa University, 3. FSI Kanazawa University)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm191S]Structure-activity relationships and pharmacokinetics studies of 125I-labeled benzimidazopyrimidine derivatives for development of SPECT probes targeting tau in Alzheimer’s disease brains

○Takeaki Kishimoto1, Hiroyuki Watanabe1, Haruka Tatsumi1, Sho Kaide1, Yuuta Tarumizu1, Shimpei Iikuni1, Yoichi Shimizu1,2, Masahiro Ono1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. Kyoto Univ. Hosp.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm192S]In vitro and in vivo evaluation of 111In-1B4M-DTPA (tiuxetan)-conjugated octreotide derivatives for application to theranostics

○Shiho Nakaue1, Nobuhiro Oshima1, Hiroki Shikanai1, Masashi Shiba1, Ryo Nakagawara1, Kanta Yamamoto1, Ryo Saito1, Hirotake Kitaura1, Hiromichi Akizawa2 (1. Health Sciences University of Hokkaido, 2. Showa Pharmaceutical University)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm193S]Structure-cellular uptake relationships of 111In-DTPA-AA−1-Asp0-D-Phe1-octreotide derivatives

○Ryo Nakagawara1, Nobuhiro Oshima1, Shiho Nakaue1, Yuu Ohmi1, Fumihiro Kondo1, Hirotake Kitaura1, Hiromichi Akizawa2 (1. Health Sciences University of Hokkaido, 2. Showa Pharmaceutical University)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm194S]Development of radiolabeled polyoxazoline for cancer-targeted internal radiotherapy: Evaluation of therapeutic effect by radiolabeled polyoxazoline combined with hyperthermia

○Tatsuya Mizukami1, Kohei Sano1,2, Toshie Tanaka1, Yuko Kanada2, Katsushi Takahashi1, Yoshie Haratake1, Natsumi Hamada1, Shota Ueno1, Yukimi Fujita1, Toshihide Yamasaki1, Masayuki Munekane1, Masahiro Ono2, Hideo Saji2, Takahiro Mukai1 (1. Kobe Pharm. Univ., 2. Grad. Sch. Pharm. Sci., Kyoto Univ.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm195S]Basic evaluation of an 211At-labeled tetrazine derivative for pretargeting system

○Yuta Kaizuka1, Hiroyuki Suzuki1, Yui Sato1, Maho Tatsuta2, Nana Washiya1, Hiroshi Tanaka2, Shigeki Watanabe3, Noriko Ishioka3, Yasushi Arano1, Tomoya Uehara1 (1. Grad. Sch. Med. Pharm. Sci., Chiba Univ., 2. Mater. Chem. Tech., Tokyo Tech., 3. QST)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm196S]Correlation between stress intensity and regional cerebral blood flow in stress model mice

○Tomoyo Nozaka1,2, Asami Ikeda1,2, Yoji Kitamura1,2, Takashi Kosaka1,2, Kazuma Ogawa1,3, Kazuhiro Shiba1,2 (1. Kanazawa University , 2. ASRC Kanazawa University, 3. FSI Kanazawa University)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm197S]Role of extracellular adenosine-generating enzyme CD73 and adenosine receptors in γ-irradiation induced migration of lung cancer cells

○sohei onozawa1, Kanami Shiina1, Kazuki Kitabatake1, Mitsutoshi Tsukimoto1 (1. Faculty of Pharm. Sci., Tokyo Univ. Sci.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm198S]Quantitative measurement of hydrogen radicals in an aqueous sample generated by x-ray irradiation

○Yusuke Makino1,2, Emiko Sekine-Suzuki2, Minako Nyui2, Megumi Ueno2, Ikuo Nakanishi2, Koji Fukui1, Ken-ichiro Matsumoto2 (1. Molecular Cell Biology Laboratory, Department of Bioscience and Engineering, College of Systems Engineering and Sciences, Shibaura Institute of Technology., 2. Quantitative RedOx Sensing Group, Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, QST.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm199S]Education and training programs using commercial available chemical reagents as radiation source

○Rikako Komatsu1, Aya Hasegawa1, Ayano Masuda1, Rikana Mikamo1, Hideki Fujino1 (1. Sch.Pharmacy,Hyogo Univ. Health Sciences)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm200S]Effectiveness evaluation of 3-boronophenylalanine as a BNCT agent

○Fuko Hirano1, Naoya Kondo1, Maho Yamashita1, Masahiko Hirata1, Takashi Temma1 (1. Osaka. Univ. of Pharm. Sci.)
2:00 PM - 4:30 PM JST(5:00 AM - 7:30 AM UTC)

[27P-pm201S]Development of CHP-calcium borate nanoparticles for boron neutron capture therapy

○Shinya Takada1, Masahiko Hirata1, Yu Katsuno1, Naoya Kondo1, Takashi Temma1 (1. Grad. Sch. Pharm. Sci., Osaka Univ of Pharm. Sci.)
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