Session Details
[27P-pm]生体分子➄／遺伝子・遺伝情報②／細胞の構造と機能➄／生体の高次構造②／生体分子⑥／細胞の構造と機能⑥／生体の高次構造③
Fri. Mar 27, 2020 2:00 PM - 4:30 PM JST
Fri. Mar 27, 2020 5:00 AM - 7:30 AM UTC
Fri. Mar 27, 2020 5:00 AM - 7:30 AM UTC
[Room P] Event Hall 1F
[27P-pm115S]Functional analysis of mutants causing ADA2 deficiency
○Mei Yamauchi1, Runa Shirai1, Moeko Ito1, Yasuhiro Watanabe1, Sachiko Iwaki-Egawa1 (1. Faculty of Pharmaceutical Science, Hokkaido University of Science)
[27P-pm116S]Evaluation of ABCG2-dependent drug resistance of a human ABC transporter ABCG2 gene SNP (rs2231137, 34 G>A, V12M and rs2231142, 421 C>A, Q141K).
○Miho Yamashita2, Megumi Tsukamoto2, Hiroshi Nakagawa1,2 (1. Department of Applied Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, 2. Department of Applied Biological Chemistry, Graduate School of Bioscience and Biotechnology, Chubu University)
[27P-pm117S]Identification of functional elements of MALAT1 long noncoding RNA in cellular stress response
○Yutaro Maeda1,2, Rena Onoguchi2, Nobuyoshi Akimitsu1,2 (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo, 2. ISC, Univ. of Tokyo)
[27P-pm118S]Development of technical basis for stabilization of in vitro synthesized RNAs
○Hiroyasu Wakida1,2, Kentaro Kawata2, Nobuyoshi Akimitsu1,2 (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo, 2. ISC, Univ. of Tokyo)
[27P-pm119S]Search for cellular proteins that bind to the fluorescent aptamer Broccoli
○RYUJI KAMIYA1, Yoshihiro Kino1, Satoh Jun-ichi1 (1. Meiji Pharm Univ.)
[27P-pm120S]Analysis of sweat secretion promotion mechanism by neuropeptide PACAP
○Yuki Hashiguchi1, Michio Yamashita1, Mayu Yamazaki1, Junko Shibato1, Takahiro Hirabayashi1, Yoshihiko Chiba1, Fumiko Takenoya1, Seiji Shioda1 (1. Hoshi Univ.)
[27P-pm121S]Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on the corneal regeneration.
○Marina Ishikawa1, Junko Shibatou1, Tomoya Nakamachi2, Takahiro Hirabayashi1, Fumiko Takenoya1, Seiji Shioda1 (1. Hoshi Univ., 2. Univ of Toyama)
[27P-pm122S]Identification of reductive metabolic enzymes of 11-keto-C19-steroids
○Yudai Kudo1, Toshiyuki Matsunaga1, Satoshi Endo1 (1. Gifu Pharmaceutical Univ.)
[27P-pm123S]Development of adjuvant drugs enhancing the therapeutic effects of Apalutamide, a new treatment for castration-resistant prostate cancer
○Jin Segawa1, Manami Hoshi1, Mina Kawai1, Mei Fujita1, Naoki Toyooka2, Naohiro Fujimoto3, Toshiyuki Matsunaga1, Akira Ikari1, Satoshi Endo1 (1. Gifu Pharmaceutical University, 2. Faculty of Engineering, University of Toyama, 3. University of Occupational and Environmental Health)
[27P-pm124S]The induction of monocarboxylate transporter 1 by chenodeoxycholic acid, bile acid in the brain, in the human astrocytic cell line A172.
○Maho Akiyama1, Yoshimitsu Kiriyama1, Ryoko Okamoto1, Minako Kadoya1, Hiromi Nochi1 (1. Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ.)
[27P-pm125S]Inhibitory effects of sudachitin on the expression of pd−1
○haruka nakashima1, Yoshimitsu Kiriyama1, Hiromi Nochi1 (1. Kagawa Sch. Pharm. Sci., Tokushima Bunri Univ.)
[27P-pm126S]Quantification of DNA damage and repair with real-time PCR
○Takayuki Iino1, Hiroaki Matusima1, Honoka Yamanaka1, Kenji Hattori1, Kazuyuki Ishii1 (1. Meiji Pharmaceutical University)
[27P-pm127S]Elucidation of the transcriptional regulatory mechanism of Fe transporter by Fur.
○rikiya ikuina1, Yosiaki Omata2, Tuyosi Kawasima1,2 (1. Lab of Mol. Biol. Grad.of pharm Sci., Yokohama Univ. Pharm, 2. Lab of Mol. Biol. faculty of pharm Sci., Yokohama Univ. Pharm)
[27P-pm128S]Isolation of the HxlR binding DNA fragments in T. volcanium with genomic SELEX
○Akari Endo1, Yosiaki Omata1, Tsuyosi Kawasima1 (1. Lab of Mol. Biol., Dept. of pharmacy Faculty of Pharm. Sci., Yokohama Univ,of Pharm.)
[27P-pm129S]Isolation of TvFur binding DNA fragments in T.volcanium with genomic SELEX
○Ami Inoue1, Satomi Nagai1, Yoshiaki Omata1, Tsuyoshi Kawashima1 (1. Lab of Mol.Biol.,Dept of Health Med.,Faculty of Pharm.Sci.,Yokohama Univ,of Pharm)
[27P-pm130S]Selection of a specific antibody against RNA polymerase using non-immune mouse antibody library
○Ikuya Takizawa1, Yoshiaki Omata1, Tsuyoshi Kawashima1 (1. Lab of Mol. Biol., Dept. of Kampo Med., Faculty of Pharm. Sci., Yokohama Univ, of Pharm.)
[27P-pm131S]The characteristics of Cas6 protein of Type III-A CRISPR-Cas system in T.volcanium.
○Kakeru Shibata1, Yoshiaki Omata1, Tsuyoshi Kawashima1 (1. Lab of Mol. Biol., Dept. of pharmacy., Faculty of Pharm. Sci., Yokohama Univ, of Pharm.)
[27P-pm132S]Analysis of regulation of expression of poly (ADP-ribose) polymerase 1 in neural stem cells.
○Ayaka Matsuda1, Suguru Kurokawa1, Rena Shigemura1, Kikuko Hotta1, Seigo Tanaka1, Masanori Takehashi1 (1. Pharm. Osaka Ohtani Univ.)
[27P-pm133S]Analysis of transcription regulatory mechanism of poly (ADP-ribose) polymerase 1 in neural stem cells
○Reina Shigemura1, Suguru Kurokawa1, Ayaka Matsuda1, Kikuko Hotta1, Seigo Tanaka1, Masanori Takehashi1 (1. Pharm. Osaka Ohtani Univ.)
[27P-pm134S]Mechanism of transcriptional repression of CYP1A2 Gene by IL-6 in HepG2 cells.
○Shota Yanagida1, Nao Yoshii1, Ayami Mori1, Atsushi Ono1, Susumu Kodama1 (1. Grad. sch . Pharm. Sci., Okayama Univ.)
[27P-pm135S]Analysis of the binding region to the dicer-related helicase DRH-3 in a novel nematode protein E1
○Takuro Murakami1, Taishi Kobayashi1, Hayato Shiraki1, Yuu Hirose1, Toshihiko Eki1 (1. Dept. Appl. Chem. Life Sci., Toyohashi Univ. Tech.)
[27P-pm136S]Nitrate phenyl butyrate induces cell death in pancreatic cancer cell
○Takuro unibercity Beppu1, Koji Nishi1, Shuhei Imoto1, Masaki Otagiri1,2, Keishi Yamasaki1,2 (1. Faculty of Pharmaceutical Sciences, Sojo University, 2. DDS Research Institute)
[27P-pm137S]Activation of JNK and p38 MAP kinase in melanoma cells cultured with nitrogen-oxide-radical activated medium
○Miki Tanaka1, Kazuma Ogawa2, Yuuki Hori2, Masahumi Ito2, Masaru Hori3, Kiyomi Hikita1, Norio Kaneda1, Tomiyasu Murata1 (1. Fac. Pharm., Meijo Univ., 2. Fac. Sci. Tech., Meijo Univ., 3. Center for Low-temperature Plasma Sciences, Nagoya Univ.)
[27P-pm138S]Anti-proliferative activity of isoflavone (S)-erypoegin K on human cancer cells
○Honoka Okunaga1, Yui Motoyama1, Minagi Kawai1, Naoki Wada1, Aoi Mizoguchi1, Kenta Matsuoka1, Kiyomi Hikita1, Tomiyasu Murata1, Naoki Asao2, Hitoshi Tanaka1, Norio Kaneda1 (1. Fac. Pharm., Meijo Univ., 2. Fac. of Textile Sci. and Technol., Shinshu Univ.)
[27P-pm139S]Effects of 6-hydroxydopamine on the expression of proteins involved in copper homeostasis
○Mao Kondo1, Hirokazu Hara1, Tetsuro Kamiya1, Tetsuo Adachi1 (1. Lab. of Clin. Pharm., Gifu Pharm. Univ.)
[27P-pm140S]Enhancement effect of hyperthermia on cancer cell injury by the treatment with plasma-activated acetate Ringerʼs solution
○Rika Ishii1, Tetsuro Kamiya1, Hirokazu Hara1, Tetsuo Adachi1 (1. Lab. of Clin. Pharm., Gifu Pharm. Univ.)
[27P-pm141S]Effect of co-culture of pancreaticβcells and monocytes on cytotoxicity by anticancer drugs
○Kana Akagi1, Misaki Ishikawa1, Akihiro Inamura1, Sanae Hirayama1, Koichi Sakurai1 (1. Hokkaido University of Science Faculty of Pharmaceutical Sciences)
[27P-pm142S]Involvement of mitochondria in cell death induced by anticancer drug that cause nuclear DNA damages
○Mizuki Imada1, Mako Kudo1, Kana Hashimoto1, Akihiro Inamura1, Sanae Hirayama1, Koichi Sakurai1 (1. Hokkaido University of Science Faculty of Pharmaceutical Sciences)
[27P-pm143S]Effect of nitric oxide on cytotoxicity in adipocytes treated with hydrogen peroxide
○Haruhi Yamada1, Yuki Nitta1, Sanae Hirayama1, Koichi Sakurai1 (1. Hokkaido University of Science Faculty of Pharmaceutical Sciences)
[27P-pm144S]Effect of Eucommia ulmoides on the expression of elastic fiber related gene in human skin fibroblast cells
○Mari Kato1, Yoshiki Kusunoki1, Hiroshi Teramoto1, Takeshi Itabashi1, Masanaho Sasatu1, Satoshi Watanabe1, Masahiro Miyashita1, Hiroshi Wachi1 (1. Hoshi Univ.)
[27P-pm145S]Molecular Regulation of Neurite Outgrowth by PACAP in PC12 Cells
○Mayuko Ishino1, Takahiro Hirabayashi1, Junko Shibato1, Michio Yamashita1, Yoshihiko Chiba1, Humiko Takenoya1, Seiji Shioda1 (1. Hoshi Univ.)
[27P-pm146S]Analysis of microglial polarization and therapeutic effect by JNK inhibitor in lysosomal storage disorders with central nervous symptoms
○Shindai Kitaguchi1, Daisuke Tsuji1, Yukiya Ohnishi1, Kohji Itoh1 (1. Grad.Sch.Pharm.Sci.,Tokushima Univ.)
[27P-pm147S]Dynamics of Podoplanin in neonatal hypoxic ischemic encephalopathy model rats
○Saki Egashira1, Katayama Yuki1, Fukumura Erina1, Kawamura Hideya1, Hotta Mitsuaki1, Irie Keichi1, Yamashita Yuta1, Nakano Takafumi1, Sato Tomomitsu1, Sano Kazunori1, Mishima Kenichi1 (1. Pharm. Fukuoka Univ.)
[27P-pm148S]Real-time FRET imaging of circadian kinase activity in ex vivo cultured SCN slices
○Youichi Tanaka1, Masao Doi1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ.)
[27P-pm149S]The study of molecular heterogeneity in mast cell granules.
○Marin Sakamoto1, Tomoyuki Kusada2, Shohei Inamoto2, Tomomi Senda2, Naohide Hirashima2, Ryo Suzuki1 (1. Fac. Pharm. Sci., Inst. Med. Pharm. and Health Sci., Kanazawa Univ., 2. Grad. Sch. Pharm. Sci., Nagoya City Univ.)
[27P-pm150S]Establishment of novel cancer testis antigen-specific TCR-transduced T cells
○Kanae Mori1, Maiko Matsushita1, Saku Saitou1, Shinya Yokoe1, Daiki Ichikawa1, Yutaka Hattori1 (1. Pharm., Keio Univ.)
[27P-pm151S]Expression of fucosylated glycan antigen sialyl Lewis X on mouse B cells
○Daichi Komiyama1, Tomohiro Takezoe1, Ryuji Matsumura2, Shigetaka Sekine1, Shogo Nishida1, Jotaro Hirakawa1, Hiroto Kawashima1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Sch. Pharm. Sci., Univ. Shizuoka)
[27P-pm152S]Effect of extracellular ATP on antigen presentation by dendritic cells.
○Hiroka Onishi1, Kento Masaki2, Satoshi Tanaka3, Chikara Kaito2, Furuta Kazuyuki2 (1. Dept. Immunobiol., Fac. Phaermac. Sci., Okayama Univ., 2. Dept. Immunobiol., Okayama Univ. Grad. Sch. Med. Dent. Pharmac. Sci., 3. Dept. Pharmacol., Kyoto Pharmac. Univ.)
[27P-pm153S]G proteins coupling and antagonism of MRGPRX2
○Haruka Watanuki1, Chikara Kaito2, Kazuyuki Furuta2, Satoshi Tanaka3 (1. Dept. Immunobiol., Fac. Pharmac. Sci., Okayama Univ., 2. Dept. Immunobiol., Okayama Univ. Grad. Sch. Med. Dent. Pharmac. Sci., 3. Dept. Pharmacol., Kyoto Pharmac. Univ.)
[27P-pm154S]The study of molecular dynamics in mast cell-neutrophil communication.
○Haruka Furusawa1, Sari Mizohata1, Naohide Hirashima1, Ryo Suzuki2 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ., 2. Fac. Pharm. Sci., Inst. Med. Pharm. and Health Sci., Kanazawa Univ.)
[27P-pm155S]Analysis of abnormal autophagy in aging
○Yukiya Ohnishi1, Daisuke Tsuji1, Kohji Itoh1 (1. Grad. Sch. Pharm. Sci., Tokushima Univ.)
[27P-pm156S]Production and characterization of pig-derived iPS cells
○akiyoshi Baba1, Tsutomu Yamasaki1, Naofumi Yamada2, Takeshige Otoi4, Fuminori Tanihara4, Sumihare Noji3, Tohru Nakanishi2 (1. Pharm. Sci., Shujitsu Univ., 2. Grad. Sch.Medical Pharm. Sci., Shujitsu Univ., 3. Tokushima Univ., 4. Grad. Sch.Social industry. Sci and eng., Tokushima Univ.)
[27P-pm157S]Obesity-induced BDNF gene expression in mouse adipose tissue
○Saki Yokokura1, Satoru Mitazaki1, Mamoru Fukuchi1 (1. Lab of Mol Neurosci, Fac of Pharm, Takasaki Univ of Hlth & Welfare)
[27P-pm158]Effect of sialic acid on Aspergillus fumigatus to eosinophil
○Masahiro Yamanaka1, Hitomi Ando1, Kasumi Tanaka1 (1. Sch. Pharm. Sci., IUHW)
[27P-pm159]Correlation of isatin concentrations in human cerebrospinal fluid and serum
○Naoya Hamaue1, Akihiko Ogata2, Keita Fukumura1, Hiromu Kondo1, Shirou Tsuchida1, Kenji Iizuka1, Takashi Aoki1 (1. Sch. of Pharm. Sci., Health Sci. Univ. of Hokkaido, 2. Dept. of Neurology, Hokkaido Neurosurgical Memorial Hospital)
[27P-pm160]Study on skin barrier function of trehangelin, a new trehalose compound
○Yoshiyuki Kamiya1, Mami Yokota1, Tamie Suzuki1, Tetsuhito Sakurai1, Takuji Nakashima2, Yoko Takahashi2, Satoshi Ōmura2 (1. FANCL Research Institute, 2. Kitasato Inst. Life Sci., Kitasato Univ.)
[27P-pm161]Effect of adipocytokine (chemerin and IGFBP2) on retinacula cutis
○Ruiko Nakanishi1, Haruka Goto1, Marie Kawabata1, Chika Inaba1, Takaya Oishi1, Nobu Mitani1 (1. POLA R&M)
[27P-pm162]HyVia :A novel chia seed extract for acne prone skin
○Daichi Kawano1, Femandez JOSE R.3, Rouzard Karl3, Webb Corey3, Healy Jason3, Huber Kristen L.3, Stock Jeffry B.4, Stock Maxwell3, Pérez Eduardo3, Liao Zhengzheng2, Chen Jing2, Fu Zihua 1 (1. Hondo Inovation Center, 2. Shanhai chicmax cosmetic Co., 3. Signum Biosciences, 4. Princeton University)
[27P-pm163]Nobiletin and Its CYP Metabolites Activate Brown Adipocytes
○Fumiko Kihara-Negishi1, Naoki Okura1, Yuka Takahashi1, Tetsuta Oshitari1, Shinji Yamaguchi1 (1. Sch. Pharm. Sci., Teikyo Univ.)
[27P-pm164]Examination of the influence by caffeine and the catechin complex on caffeine absorption
○Saki Takeda1, Chihiro Nakazaki2, Kento Ito1, Kazuki Noto1, Toshio Motoyashiki1 (1. Fuculty.Pharm.Sci,Fukjuyama Univ., 2. Fuculty.Life.Sci.Bio,Fukjuyama Univ.)
[27P-pm165]Biosynthetic route of pyrimidine moiety of thiamin under anaerobic condition in Saccharomyces cerevisiae.
○Kosuke Yamashita1, Kazuki Imoto1, Maria Hayashi2, Kazuto Nosaka2, Hiromi Kataoka2, Makoto Hiromura1, Keiko Tazuya-Murayama1 (1. Daiichi University of Pharmacy, 2. School of Pharmacy and Pharmaceutical Sciences Mukogawa Women’s University)
[27P-pm166]Cytotoxicity of amphiphilic helical peptides composed of arginine and leucine only (2)
○Akihiro Ambo1, Koki Sasaki1, Masayuki Seki1 (1. Tohoku Med. Pharm. Univ.)
[27P-pm167]Inhibitory mechanism of glucose uptake by targeting Na+,K+-ATPase α3-isoform in cancer cells
○Takuto Fujii1, Manami Ootsubo1, Nguyen Thi Tu Oanh1, Mizuki Kato1, Takahiro Shimizu1, Hiroshi Takeshima2, Hideki Sakai1 (1. Grad Sch Med Pharm Sci, Univ Toyama., 2. Grad. Sch. Pharm. Sci., Kyoto Univ.)
[27P-pm168]Glycine to asparagine mutaion in LAMP-1's lysosome-targeting signal (GYQTI) caused its reduced transport to lysosomes
○Kenji Akasaki1, Hiroshi Sakane1, Toshiyuki Hata1 (1. Fac. Pharm. Sci., Fukuyama Univ.)
[27P-pm169]Functional analysis of GPR19 as an antigen for cancer vaccine by rescue experiment in GPR19 knock-out cells.
○Masanori Mizutani1, Norikazu Mizuno1 (1. Clin. Pharm., Aomori Univ.)
[27P-pm170]5-HT2A receptor antagonist sarpogrelate significantly suppressed cardiomyocyte
hypertrophy
○Yoshiki Kawakami1, Kana Shimizu1,2, Yoichi Sunagawa1,2,3, Masafumi Hunamoto1,2, Yasufumi Katanasaka1,2,3, Yusuke Miyazaki2,1,3, Daiki Honda1, Nurmila Sari1, Satoshi Shimizu1,2, Hiromichi Wada2, Koji Hasegawa1,2, Tatsuya Morimoto1,3,2 (1. Pharm.Sci.,Shizuokaken Univ., 2. NHO, Kyoto Med Center, 3. Shizuoka Gen Hosp)
[27P-pm171]Regulation of vascular endothelial cell signaling pathway by selenoprotein P
○Suguru Kurokawa1, Masanori Takehashi1 (1. Pharm. Osaka Ohtani Univ.)
[27P-pm172]Suppression of IL-6 induced JAK-STAT pathway by Zinc(II) Complex
○Makoto Hiromura1, Yu Sato1, Takayuki Koga1, Fumio Soeda1, Akihisa Toda1, Keiko Tazuya-Murayama1 (1. Daiichi Univ. Pharm.)
[27P-pm173]Analysis of Niemann-Pick disease type C protein 2 expression change during PC12 cell differentiation
○Mami Hino1, Masashi Saiki1, Asuka Kashiwagi1, Takahisa Sasaki1, Masayuki Nakanishi1, Hiroshi Nomoto1 (1. Coll Pharm Sci, Matsuyama Univ)
[27P-pm174]Screening inducers of neuronal BDNF gene expression from pharmacologically validated compounds
○Mamoru Fukuchi1 (1. Lab of Mol Neurosci, Fac of Pharm, Takasaki Univ of Hlth & Welfare)
[27P-pm175]Alteration of BRINP family gene expressions in hippocampus of pilocarpine-induced epileptic model mouse
○Miwako Kobayashi1, Daisuke Ochi1, Eriko Uno1, Ichiro Matsuoka1 (1. Col. of Pharm. Sci., Matsuyama Univ., Matsuyama, Japan)
[27P-pm176]Effect of thyroid hormone on occurrence of neuronal death following cerebral ischemia-reperfusion in mice.
○Masaru Doshi1, Shiro Watanabe2, Yujin Natori3, Makoto Hosoyamada1, Yutaka Akae4 (1. Faculty of Pharma-Sciences, Teikyo University, 2. Instisute of Natural medicine, University of Toyama, 3. Department of Legal Medicine and Bioethics, Nagoya University Graduate School of Medicine, 4. Akae clinic)
[27P-pm177]D-Serine and NMDA receptor regulate adaptive foraging behavior in Caenorhabditis elegans
○Yasuaki Saitoh1, Tetsuya Miyamoto1, Masae Sekine1, Masumi Katane1, Kumiko Sakai-Kato1, Hiroshi Homma1 (1. Sch. Pharm. Sci., Kitasato Univ.)
[27P-pm178]Behavioral and histological analysis of neurodevelopmental disorders-associated genes, doublecortin-like kinases knockout mouse
○Hiroyuki Koizumi1, Chisato Mitobe2, Kei Okuyama2, Yuki Aoyama3, Kazuya Togashi2, Taku Nagai3, Kiyofumi Yamada3, Yukihiro Noda4, Kazuo Emoto2 (1. Sch. Pharm. Sci., Ohu Univ, 2. Grad. Sch. Sci., Univ. Tokyo, 3. Grad. Sch. Med., Nagoya Univ., 4. Fac. Pharm., Meijo Univ.)
[27P-pm179]Mechanical hyperalgesia induced by a high-fat-cholesterol diet in SHRSP5/Dmcr rats: Possible involvement of the medullary pain modulation systems
○Karen Kawase1, Reina Aikawa1, Sayaka Ario1, Tomomi Miyazaki1, Chiho Kawabata1, Hinako Suzuki1, Daisuke Miyazawa1, Kazuya Kitamori2, Yasuko Kozaki1 (1. Coll.Pharmacy, Kinjo Gakuin Univ., 2. Coll.Human Life and Enviroment, Kinjo Gakuin Univ.)
[27P-pm180]Roles of Bmal1 "a clock gene" in energy metabolism.
○Shigeki Shimba1, Taira Wada1, Hirotake Ishii1, Hideki Hoshina1 (1. Department of Health Science, School of Pharmacy, Nikon University)