Session Details
[27P-am]分光分析・機器分析・生物学的分析法・その他
Fri. Mar 27, 2020 9:00 AM - 11:30 AM JST
Fri. Mar 27, 2020 12:00 AM - 2:30 AM UTC
Fri. Mar 27, 2020 12:00 AM - 2:30 AM UTC
[Room P] Event Hall 1F
[27P-am104]The new challenge of nondestructive analysis for medical inheritances: preliminary study of utilization of muonic X-ray analysis
○Kayoko Shimada Takaura1,2, Kazuhiko Ninomiya3, Akira Sato3, Naomi Ueda4, Hisateru Amenomori4, Motonobu Tampo5, Soshi Takeshita5, Yasuhiro Miyake5, Kyoko Takahashi1,2 (1. Museum Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Grad. Sch. Sci., Osaka Univ., 4. Gangoji Inst. Res. Cultur. Prop., 5. KEK Inst. Mater. Struct. Sci.)
[27P-am105]Solid phase extraction conditions of vancomycin in urine for fluorescent fingerprint analysis
○Masaru Kato1, Yuki Ohshima1, Yuhei Kamota1, Miho Yoshihara1, Koji Karasawa1, Shuhei Murayama1 (1. Sch. Pharmacy, Showa Univ.)
[27P-am106]Development of quinazolinone fluorescent probe for selective detection of carbon monoxide
○Naoya Kishikawa1, Yuusuke Sakamoto2, Naotaka Kuroda1 (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Sch. Pharm. Sci., Nagasaki Univ.)
[27P-am107]Spectroscopic analysis for quality evaluation of commercial pharmaceuticals IX. Quality Analysis of Counterfeit or Substandard Suspected Personal Imported Pharmaceuticals using HPLC, NIR Imaging, THz and Raman Spectroscopy
○Tomoaki Sakamoto1,2, Tetsuo Sasaki2,3, Yasuto Fujimaki4, Toshiyuki Chikuma1 (1. NIHS, 2. RIE, Shizuoka Univ., 3. Med.Photo., Grad.Sch., Shizuoka Univ., 4. TIRI)
[27P-am108]Effect of low content enantiomer impurity molecule observed by THz spectroscopy
○Tetsuo Sasaki1,2, Tomoaki Sakamoto2,3, Makoto Otsuka4 (1. Grad. Sch. Medical Photonics., Shizuoka Univ., 2. RIE, Shizuoka Univ., 3. NIHs, 4. Pharm., Musashino Univ.)
[27P-am109]Development of a distinction method of production area of Picrasma quassioides using fluorescence fingerprint measurement
○Yasunori Hamazaki1, Takemasa Harashima2, Masako Yaguchi1, Toshiaki Yoshie1, Koji Karasawa2, Shuhei Murayama2, Masaru Kato2 (1. OHTA'S ISAN, 2. Sch. Pharm, Showa Univ.)
[27P-am110]Development of Near infrared fluorophores using Crystallization induced emission mechanism
○Toshinobu Masuda1, Kazutaka Koga1, Tomonori Shiratani1, Katsumi Kido1, Sayuri Yokoyama1 (1. Daiichi University of Pharmacy)
[27P-am111]Analysis of renal stones from a Tutsi whale and a bottlenose dolphin with the use of X-ray diffraction and IR spectrometry
○Kiyoko Kaneko1, Masaki Ishii1, Akira Oozeki1, Tomoko Fukuuchi1, Noriko Yamaoka1, Keiichi Ueda2, Miwa Suzuki3, Akira Nishiyama4 (1. Teikyo University, Faculty of Pharma-Science, Laboratory of Biomedical and Analytical Sciences, , 2. Okinawa Churashima Foundation Research Center, 3. Nihon University, College of Bioresource Sciences, Department of Marine Science and Resources, 4. Kagawa University, Faculty of Medicine, Department of Pharmacology)
[27P-am112]Observations of pharmaceutical tablet under severe environment by non-destructive technology - X-ray CT images and NIR spectral analysis -
○Yasuto Fujimaki1, Shinichi Tomiyama1, Tomoaki Sakamoto2,3 (1. Tokyo Metropolitan Industrial Technol. Res. Inst., 2. National Institute of Health Sciences, 3. Research Institute of Elecrtronics, Shizuoka Univ.)
[27P-am113]X-ray absorption fine structure analyses of bromhexine hydrochloride in crystalline forms.
○Zhenni Huang1, Hironori Suzuki1, Masataka Ito1, Shuuji Noguchi1 (1. Graduate Institute of Pharmaceutics,Toho University)
[27P-am114S]Digital image-based flow ratiometric titration for drugs using RGB-based detecter
○Naoya Kakiuchi1, Junya Ochiai2, Masaki Takeuchi1,2, Hideji Tanaka1,2 (1. Grad. Sch. Pharm. Sci., Tokushima Univ., 2. Fac. Pharm. Sci., Tokushima Univ.)
[27P-am115]Monitoring of API's hydration with frequency domain terahertz spectroscopy
○Touya Ono1, Kei Shimura1, Mizuki Mohara1, Kenji Aiko1 (1. Hitachi high-technologies corp.)
[27P-am116]Drug dissolution monitoring using terahertz attenuated total reflection spectroscopy
○Kazuki Horita1, koichiro akiyama1, kazuhiro takahashi1, tomoaki sakamoto2, hiroshi satozono1 (1. HAMAMATSU PHOTONICS, 2. NIHS)
[27P-am117]Monitoring of lactic acid fermentation process by using terahertz attenuated total reflection spectroscopy 2.
○Koichiro Akiyama1, Kazuki Horita1, Kazuhiro Takahashi1, Tomoaki Sakamoto2, Hiroshi Satozono1 (1. HPK, 2. NIHS)
[27P-am118S]Development of simple evaluation method with intercellular lipids as indicator for irritation due to surfactant
○Yutaka Goto1, Suzuko Terayama2, Mika Fujii1, Toshiro Fukami1 (1. Meiji Pharmaceutical University, 2. Milott Cosmetic Corporation)
[27P-am119]Identification of binding sites of anti-inflammatory drug diclofenac on HSA molecule by using isothermal titration calorimetry
Ayaka Sampei1, Shogo Hara1, ○Hiroyasu Ohtaka1, Kanji Sugimoto1, Akimasa Shibukawa1 (1. Faculty of Pharmacy, Chiba Institute of Science)
[27P-am120S]Identification of HSA-Irbesartan binding site on HSA molecule by using isothermal titration calorimetry
○Chisato Higeta1, Yuto Uchiyama1, Ayaka Sampei1, Ohtaka Hiroyasu1, Kanji Sugimoto1, Akimasa Shibukawa1 (1. Faculty of Pharmacy, Chiba Institute of Science)
[27P-am121S]DSC analysis of structural stability of HSA molecule caused by diclofenac
○Ayaka Sampei1, Shogo Hara1, Hiroyasu Ohtaka1, Kanji Sugimoto1, Akimasa Shibukawa1 (1. Faculty of Pharmacy, Chiba Institute of Science)
[27P-am122]Investigations for mechanisms of DMPO spin adduct using Lipid.
○Mika Tada1 (1. Center for General Education, Tohoku Institute of Technology)
[27P-am123S]Evaluation of NMR spectrum reconstruction from low-SNR FID signals based on sparse modeling methods
Sarasa Tagami1, Shou Nakadate1, ○Yuichi Kida1 (1. Pharm. Sci., Ohu Univ.)
[27P-am124]Development of redox metabolic imaging for NASH using in vivo Dynamic Nuclear Polarization MRI
○Fuminori Hyodo1, Hinako Eto2, Tomoko Nakaji3, Tatsuya Naganuma3, Ryosuke Nakata2,4, Shinichi Shoda1, Masaharu Murata2, Masayuki Matsuo1 (1. Grad. Sch. Med., Gifu Unive., 2. Inovation Ctr. Kyushu. Unive., 3. Japan Redox Inc., 4. Nippon Med Sch. Unive.)
[27P-am125]Effect of substrate and temperature on stiffness measurement of nanoscale liposomes by use of atomic force microscopy
○Yuki Takechi-Haraya1, Kenichi Izutsu1, Kumiko Sakai-Kato2 (1. Division of Drugs, National Institute of Health Sciences, 2. School of Pharmacy, Kitasato University)
[27P-am126]Development of stress evaluation method using saliva and analysis of stress-related substances
○Yuki Odanaka1, Yuuna Kaneko1, Yuka Shigeno1, Akiko Sasaki2, Masaru Kato1 (1. Sch. Pharm. Showa Univ., 2. Sch. Med. Showa Univ.)
[27P-am127]Quantitative analysis of dabigatran’s concentration in human blood using peptide substrate
○Satoko Shono1, Ryo Matsuda1, Hinako Hatae1, Hiroyuki Kuma1 (1. Pharm.Sci.,nagasaki International Univ.)
[27P-am128S]Development of the new protein C-activity assay
○Momoka Hamasaki1, Misuzu Shigeta1, Ryou Matuda1, Hinako Hatae1, Hiroyuki Kuma1 (1. Pharm.Sci.,Nagasaki International Univ.)
[27P-am129]Improvement in accuracy of voids inside pharmaceutical tablets using X-ray CT images
○Shinichi Tomiyama1, Yasuto Fujimaki1, Tomoaki Sakamoto2,3 (1. Tokyo Metropolitan Industrial Technology Research Institute, 2. National Institute of Health Sciences, 3. Research Institute of Electronics, Shizuoka University)
[27P-am130]Simplified measurement of sesamol by electrochemical detection
○Ken-ichi Ohno1, Masayuki Kumano2, Katsuhiko Sato3, Tsutomu Fujimura1 (1. Fac. Pharm. Sci., Tohoku Med. Pharm. Univ., 2. Fac. Pharm. Sci., Tohoku Univ., 3. Grad. Sch. Pharm. Sci., Tohoku Univ.)
[27P-am131S]Development of evaluation method for therapeutic effects of antibody drugs using imaging technology.
○Sari Sekiguchi1, Hiroyuki Kimura1, Susumu Nakata1, Hiroya Taniguchi2, Hiroyuki Yasui1 (1. Kyoto Pharmaceutical University, 2. National Cancer Center Hospital East)
[27P-am132]Effect of replacement of VL49 cysteine in anti-cortisol scFv on the antigen-binding ability
○Yuki Kiguchi1, Hiroyuki Oyama1, Izumi Morita1, Kaho Murayama1, Norihiro Kobayashi1 (1. Kobe Pharm. Univ.)
[27P-am133S]In vitro affinity maturation of anti-estradiol scFv based on mutagenesis targeting VH FR1
○Miku Taguchi1, Yasuhiro Nagata1, Naoko Umezawa1, Yuka Higashi1, Hiroyuki Oyama1, Yuki Kiguchi1, Izumi Morita1, Norihiro Kobayashi1 (1. Kobe Pharm. Univ.)
[27P-am134S]Systematic analysis of in vitro affinity maturation process of an anti-estradiol scFv
○Yuka Higashi1, Miku Taguchi1, Hiroyuki Oyama1, Yuki Kiguchi1, Izumi Morita1, Norihiro Kobayashi1 (1. Kobe Pharm. Univ.)
[27P-am135S]Characterization of anti-Δ9-tetrahydrocannabinol scFv mutants generated by substitution of tyrosine residues in VL-CDR
○Yui Kuwahara1, Hiroyuki Oyama1, Izumi Morita1, Norihiro Kobayashi1 (1. Kobe Pharm. Univ.)
[27P-am136]Quantitative detection of AFP using magnetic immunoassey system
○Mai Shirabe1, Runa Hayase1, Hinako Hatae1, Keiji Enpuku2, Hiroyuki Kuma1 (1. Pharm.Sci.,nagasaki International Univ., 2. Grad.Sch.,kyusyu International Univ.)
[27P-am137]Detection of fomivirsen by ligase chain reaction
○Naoki Harikai1, Akihiro Araki1, Kazumasa Zaima1, Kazufusa Shinomiya1 (1. Sch. Pharm., Nihon Univ.)
[27P-am138S]Development of amino acid isomerization site identification method using chemical proteomics approach
○Ami Yamaguchi1, Hiromasa Tsuruta1, Shota Morimoto1, Yutaka Sadakane1 (1. Pharm. Sci., Suzuka Univ. of Med. Sci. )
[27P-am139]Investigation of the conditions for reproducible formation of amyloid fibers and screening of the inhibitor against fibril formation
Chisa Iwakawa1, Yuka Morishita1, Shota Morimoto1, ○Yutaka Sadakane1 (1. Suzuka Univ. Med.Sci.)
[27P-am140S]Preparative method for photoreactive DNA aptamer that enables to analyze under denature condition.
○Chihiro Hrai1, Shota Morimoto1, Yutaka Sadakane1 (1. Suzuka Univ. Med. Sci.)
[27P-am141]Spectroscopic analysis for quality evaluation of commertial pharmaceuticals X Quality analysis of Fexofenadine Hydrochloride Tablet by Raman imaging spectroscopy
○Toshiyuki Chikuma1, Tomoaki Sakamoto1 (1. NIHS)
[27P-am142]Quantitative analysis of mRNA in the inhibitory effect of Lactobacillus sakei UONUMA strain on cholesterol biosynthesis enzyme system
Eriko Tomitsuka1, ○Saori Nakagawa1, Miho Shimizu-Ohta1, Fumiko Fuwa1, Toshikazu Nishiwaki2, Kotaro Aihara2, Shinji Sato1 (1. NUPALS, 2. Food Research Center, Niigata Agricultural Research Institute)
[27P-am143]Docking simulation of 5-mer Catalytide with Aβ1-20
○Motomi Konishi1, Toi Ishii1, Yusuke Hatakawa2, Rina Nakamura3,4, Toshifumi Akizawa3,4 (1. Pharm. Sci., Setsunan Univ. , 2. Kobe Pharm. Univ., 3. Med. Sch. Kochi Univ., 4. O-Force Co., Ltd.)
[27P-am144]Electrochemical detection of vancomycin using TEMPO
○Katsuhiko Sato1, Masayuki Kumano1, Tetsuya Ono2, Kentaro Yoshida2, Takenori Dairaku2, Yoshitomo Kashiwagi2 (1. Grad. Sch. Pharm. Sci., Tohoku Univ., 2. Pharm. Sci., Ohu Univ.)
[27P-am145S]Preliminary study on the detection of γ-glutamyltransferase by glutathione-modified polydiacetylene liposomal aequorin bioluminescent device
○Ai Kodama1, Shigehiko Takegami1, Atsuko Konishi1, Tatsuya Kitade1 (1. Kyoto Pharm. Univ.)
[27P-am146S]Improvement of selectivity of histamine potentiometric sensor based on molecularly imprinted polymer by chemical modification of functional monomer on polymer surface
○Yoko Idosaki1, Atsuko Konishi1, Shigehiko Takegami1, Tatsuya Kitade1 (1. Kyoto Pharm. Univ.)
[27P-am147]Brain redox imaging in the CNS disorder-model mice
○Akihiko Kuniyasu1, Yuuka Kouguchi1, Kouki Fukuoka1, Miho Kashio1, Masaki Makise1, Koji Hashimoto2, Tetsuya Yoneda2, Shoko Okazaki1, Keizo Takeshita1 (1. Fac. Pharm. Sci., Sojo Univ., 2. Grad. Sch. Health Sci., Kumamoto Univ.)
[27P-am148]NMR analysis: Mechanism of Drug-Cyclodextrin Clathrate and Relationship to Bitterness
○Tomohiko Ueda1 (1. Sumitomo Dainippon Pharma Co., Ltd. Technology Reseach & Development Division Analytical Reseach & Development Laboratories)
[27P-am149]Establishment of multi-sample solubility and solution stability evaluation system in drug discovery research
○Shinnosuke Hayashi1, Shingo Asano1, Motohiro Shiraki1 (1. Toray Industries, Inc. Pharmaceutical Research Laboratories.)
[27P-am150S]Evaluation method of α-amylase inhibitory activity using PVPP pretreatment.
○Rina Tanaka1, Saya Tamamura1, Satoko Nishimura2, Chisato Takahashi1, Keiko Maekawa1, Yuji Yamauchi1 (1. Faculty of Pharm. Sci., Doshisha Women's Col., 2. PMRJ)
[27P-am151]Three-dimensional tissue array for high-throughput drug screening
○Midori Negishi1,2, Jun Sawayama2, Masahiro Kawahara1, Shoji Takeuchi2,3 (1. Musashino Univ., 2. IIS, The University of Tokyo, 3. The University of Tokyo)
[27P-am152S]Improved preparative purification efficiency with the column that shows great chemical stability.
○Yuki Obata1, Hiroshi Sakamaki1 (1. Chemicals Evaluation and Research Institute, Japan)
[27P-am153]Recovery of o-phenylphenol by precolumn derivatization with 3,5-dinitrobenzoyl chloride after solid phase extaction
○Natsuki Hayashi1, Yuna Shoji1, Yasuhiko Higashi1 (1. Hokuriku Univ.)
[27P-am154]Development of simultaneous determination of four selective serotonin reuptake inhibitors by HPLC-UV after precolumn derivatization with 3-methoxybenzoyl chloride
○Yuuya Yokota1, Yasuhiko Higashi1 (1. Hokuriku Univ.)
[27P-am155S]Analysis of D,L-amino acids in Miso using FDLA pre-column derivatized LC/MS/MS method.
Ayaka Haranosono2, ○Yusuke Takano1, Marina Miwatari2, Masaki Kobayashi1,2, Masaru Niitsu2, Takemitsu Furuchi1,2 (1. Grad. Sch. Pharm. Sci., Josai Univ., 2. Sch. Pharm. Sci., Kyoto Univ.)
[27P-am156]Analysis of D,L-amino acids using chiral pre-column derivatized GC method.
○Koki Yajima1, Yukiko Ogawa1, Masaki Kobayashi1, Masaru Niitsu1, Takemitsu Furuchi1 (1. Sch. Pharm. Sci., Josai Univ.)
[27P-am157]Analysis of D,L-amino acids in yogurt using FDLA pre-column derivatized LC/MS/MS method.
○Fuka Miyamoto1, Kosuke Nishi1, Yusuke Takano2, Masaki Kobayashi1,2, Masaru Niitsu1, Takemitsu Furuchi1,2 (1. Sch. Pharm. Sci., Josai Univ., 2. Grad. Sch. Pharm. Sci., Josai Univ.)
[27P-am158S]Analysis of D,L-amino acids in fruits juice using FDLA pre-column derivatized LC/MS/MS method.
○Shunsuke Kimura1, Yusuke Takano2, Masaki Kobayashi1,2, Niitsu Masaru1, Takemitsu Fruchi1,2 (1. Sch. Pharm. Sci., Josai Univ., 2. Grad. Sch. Pharm. Sci., Yotai Univ.)
[27P-am160]Chiral separation of (R/S)-baclofen using Nα-(5-fluoro-2.4-dinitrophenyl)-L-leucinamide
○shinsuke miyazaki1, Yasuhiko Higashi1 (1. Hokuriku Univ.)
[27P-am161]A method for in vitro measurement of oxidized low-density lipoprotein in blood, using fluorescence-labeled peptide and polyethylene glycol
○Akira Sato1,2, Keiichi Ebina1,2 (1. Fac. Pharm., Iryo Sosei Univ., 2. Grad. Sch. Sci. Eng., Iryo Sosei Univ.)
[27P-am162]Novel method for simultaneous quantification of epidermal growth factor receptor-tyrosine kinase inhibitors and anaplastic lymphoma kinase inhibitors in human serum
○Yuji Mukai1, Tatsunari Yoshida2, Nobuo Inotsume1, Takaki Toda1 (1. Faculty of Pharmaceutical Sciences, Hokkaido University of Science, 2. Biotage Japan)
[27P-am163S]Simultaneous quantification of bile acids in the brain of mice by LC-MS/MS
○Miyaji Yusuke1, Hinako Sano1, Natsuki Aikawa1, Masayuki Kai1, Shoichi Kusunose1, Sin Koike1, Toshihiro Suzuki1, Yuki Ogasawara1 (1. Meiji pharm. Univ.)
[27P-am164S]Development of specific adsorbents for halogenated phenols
○Mitsuki Kokubo1, Takara Koide1, Ryohei Yamamoto1, Atsushi Yamamoto1, Toshio Miwa2, Yoshitaka Hayashi3 (1. Coll.BioSci.Biotech.,Chubu, 2. Thermo Fisher Scientific, 3. Tohoku Ryokka Kankyohozen)