Session Details
[28P-am]物理化学一般②／生体高分子②／生体膜・人工モデル膜②／物理的計測バイオイメージング②／構造生物学②・その他／情報・計算化学②
Sat. Mar 28, 2020 9:00 AM - 11:30 AM JST
Sat. Mar 28, 2020 12:00 AM - 2:30 AM UTC
Sat. Mar 28, 2020 12:00 AM - 2:30 AM UTC
[Room P] Event Hall 1F
[28P-am208S]Sugar responsive rheological studies in diboronic acid derivative/polyvinyl alcohol mix system
○Masato Yamazaki1, Ryotaro Miki1, Yuya Egawa1, Toshinobu Seki1 (1. Faculty of Pharm. Pharm. Sci., Josai Univ.)
[28P-am209S]Effects of N-terminal acylation on stability and structure of peptide self-assembly
○Ai Sato1, Keisuke Ikeda1, Hiroyuki Nakao1, Minoru Nakano1 (1. Grad. Sch. Pharm. Sci., Toyama Univ.)
[28P-am210]Fluorescence responses of 4-(1-pyrenyl)phenylboronic acid towards saccharides in the presence of ionic surfactant
○Suzuki Iwao1, Yota Aikawa1, Honami Koyama1, Nao Konishi1, Rina Oshima1, Shigehiro Takahashi1 (1. Faculty of Pharmacy, Takasaki University of Health and Welfare)
[28P-am211S]X-ray absorption near edge spectroscopy analyses of cimetidine crystal polymorphs
○Masahito Matsushima1, Hironori Suzuki1, Masataka Ito1, Shuji Noguchi1 (1. Toho Univ.)
[28P-am212]State analysis of active ingredients in loxoprofen preparation
○Chisato Tode1, Naoto Hata1, Miho Morimoto1, Atsuko Takeuchi1 (1. Kobe Pharmaceutical Univ.)
[28P-am213]Electrochemical generation of electrophilic compounds from phenol derivative
○Kayoko Tahara1 (1. Kyushu Univ. Health Welfare)
[28P-am214]Development of high-throughput sample plates and preparation methods (XRD, Raman spectroscopy) for salt and crystal polymorphism screening of drug substances that can handle chemical hazard substances
○Takahiko Hashizuka1 (1. Analytical Research & Development Laboratories, Sumitomo Dainippon Pharma. Co., Ltd)
[28P-am215]Photoprotective effects of amino acids on the photodegradation of naproxen solution
○Kohei Kawabata1, Momoka Kanoh1, Mayu Okazaki1, Rina Maeda1, Satomi Mori1, Masanori Inagaki1, Hiroyuki Nishi1 (1. Yasuda Women's Univ.)
[28P-am216]Effect of oxygen concentration in helium gas of cold atmospherc plasma on the generation of reactive oxygen species by irradiation of water
○Kazunori Anzai1, Hitoshi Ishiyama1, Daisuke Watanabe1, Anna Asano1, Hajime Shimura1, Kazunori Tsuchida1, Tokuko Takajo1 (1. Nihon Pharm. Univ.)
[28P-am217]ESR detection of singlet oxygen generated by irradiation of cold atmospheric pressure plasma jet to water.
○Tokuko Takajo1, Katsuya Zuinen1, Kazunori Tsuchida1, Kazunori Anzai1 (1. Nihon Pharm.Univ.)
[28P-am218]Lipid peroxidation of large unilamellar vesicles by the irradiation of cold atmospheric plasma
○Kazunori Tsuchida1, Kenta Ueno1, Shiori Fukuda1, Ako Fukutomi1, Koichi Saito1, Tokuko Takajo1, Kazunori Anzai1 (1. Nihon Pharm. Univ.)
[28P-am219]Molecular studies to elucidate the substrate recognition mechanism of IDO1
○Hirofumi Tsujino1, Taku Yamashita2, Takeshi Saiki1, Shotaro Maeda1, Kazuki Takada1, Kazuma Higashisaka1,3, Kazuya Nagano1,3, Tadayuki Uno1, Yasuo Tsutsumi1,3,4 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Sch. Pharm. Sci., Mukogawa Women’s Univ., 3. Grad. Sch. Med., Osaka Univ., 4. MEI Center, Osaka Univ.)
[28P-am220]Stable conformer of nonivamid in water investigated by theoretical study
○Kaoru Tanaka1 (1. Faculty of Health Sciences,Kyorin Univ.)
[28P-am221S]Construction of CYP-drug binding affinity evaluation system by using metal nanoparticles
○Hiroki Takenaka1, Hirofumi Tsujino1, Mami Okuno1, Kazuma Higashisaka1,2, Kazuya Nagano1, Taku Yamashita3, Tadayuki Uno1, Yasuo Tsutsumi1,2,4 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Med., Osaka Univ., 3. Sch. Pharm. Sci., Mukogawa Women's Univ., 4. MEI Center, Osaka Univ.)
[28P-am222S]Effect of single nucleotide polymorphism on electron transfer from cytochrome P450 oxidoreductase to CYP2C9/19
○Yurie Tada1, Hirofumi Tsujino1, Azusa Sakamoto1, Shumma Nishimura1, Taku Yamashita2, Kazuma Higashisaka1,3, Kazuya Nagano1, Tadayuki Uno1, Yasuo Tsutsumi1,3,4 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Sch. Pharm. Pharmaceut. Sci., Mukogawa Women’s Univ., 3. Grad. Sch. Med., Osaka Univ., 4. MEIC, Osaka Univ.)
[28P-am223S]Fractionation and bioactive evaluation of oxidized phospholipids generated by non-enzymatic lipid peroxidation
○Akihiro Iwao1, Yuta Matsuoka1,2,3, Ken-ichi Yamada1,2,3 (1. Sch. Pharm. Sci., Kyushu Univ., 2. Grad. Sch. Pharm. Sci., Kyushu Univ., 3. AMED-CREST)
[28P-am224S]A study of the defense effects of 2-hydroxyestradiol or 2-hydroxyestradiol 17-sulfate for MCF-7 cell’s injury by an azo compound
○Naoto Ishika1, Shoya Izumi1, Yoshihiro Mihara1, Shinji Itoh1, Kaori Takanashi1 (1. Hokkaido University of Science)
[28P-am225]Analysis of the process of fibril formation on monomeric/multimeric α-synuclein involved in Parkinson’s disease
○Takuya Murata1, Yuka Unno1, Naoko Tate1 (1. Fac. Pharm. Sci., Teikyo Univ.)
[28P-am226S]Evaluation of H2O2 generation ability and redox properties of catechol derivatives in the presence of metal ions.
○Mai Mikazuki1, Honami Mori1, Kayo Ikegami1, Takao Takeuchi1, Takuhei Yamamoto2, Bunji Uno2, Noriko Okumura1 (1. Kinjo Gakuin University, 2. Gifu Pharmaceutical University)
[28P-am227S]The reduction potential of cytidine/AgI (2:1) complex in DMSO solution
○Rika Kawai1, Takenori Dairaku1, Tetsuya Ono1, Kentaro Yoshida1, Jiro Kondo2, Akira Ono3, Yoshiyuki Tanaka4, Yoshitomo Kashiwagi1 (1. School of Pharmaceutical Sciences, Ohu University, 2. Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 3. Department of Material & Life Chemistry, Faculty of Engineering Kanagawa University, 4. Faculty of Phamaceutical Scienes, Tokushima Bunri University)
[28P-am228]Evaluation of electrocatalytic activity of organic nitroxyl radicals in neutral aqueous media
○Shogo Yashiro1, Tetsuya Ono1, Katsuhiko Sato2, Yusuke Sasano2, Takenori Dairaku1, Kentaro Yoshida1, Yoshiharu Iwabuchi2, Yoshitomo Kashiwagi1 (1. Sch. Pharm. Sci., Ohu Univ., 2. Grad. Sch. Pharm. Sci., Tohoku Univ.)
[28P-am229]Investigation of Diquat Inclusion Complex Formation Using Cucurbit[n]uril and Cyclodextrin
○Hiroyuki Tsutsumi1, Tomonori Ohata1, Miho Yukawa1, Hirohito Ikeda1 (1. Faculty of Pharmaceutical Sciences, Fukuoka University)
[28P-am230]Study on dimerization of water–soluble decaphenylporphyrin iron complex
○Hirofumi Konno1, Jun Takeda1 (1. Faculty of Pharma-Science, Teikyo University)
[28P-am231S]Effect of substituents in homolysis rate of TEMPO-type alkoxyamines
○Mao Sakamoto1, Toshihide Yamasaki1, Kohei Sano1, Masayuki Munekane1, Takahiro Mukai1 (1. Kobe Pharm. Univ.)
[28P-am232]Analysis of thermodynamic profile of β-cyclodextrin-phenobarbital and -cyclobarbital inclusion complexes
○Isao Nakanishi1, Yuka Sakai1, Yuka Honda1, Natsuki Nishino1, Natsuko Taniguchi1, Maki Sato1, Tadashi Kamiyama2, Keiji Nishiwaki1 (1. Fac. Pharm., Kindai Univ., 2. Fac. Sci. and Eng., Kindai Univ.)
[28P-am233]DNA polymorphism
○Risa Ito1, Miyuki Ohshiro1, Yuuko Muro1, Ryouta Tamaki1, Kyouko Matsushita1, Mana Watanabe1, Ryouta Kiura1, Hirotsugu Miyashiro1 (1. Yokohama Univ. Pharm.)
[28P-am234S]RNA polymorphism
○Sarina Kurihara1, Mayu Yasuda1, Yuuko Muro1, Ryouta Tamaki1, Kyouko Matsushita1, Mana Watanabe1, Ryouta Kiura1, Hirotsugu Miyashiro1 (1. Yokohama Univ. Pharm.)
[28P-am235S]Amyloidogenic segment entropically drives nucleation in fibril formation by ApoA-I
○Norihiro Namba1, Miho Nakagawa1, Mizuki Kimura1, Misae Sakai1, Takashi Ohgita1, Hiroyuki Saito1 (1. Kyoto Pharm. Univ.)
[28P-am236S]Dual effects of ApoE in ApoA-I fibril formation
○Miyu Nakano1, Mao Kamata1, Chiharu Mizuguchi1, Takashi Ohgita1, Hiroyuki Saito1 (1. Kyoto Pharm. Univ.)
[28P-am237S]Promotion of phospholipid flip-flop by dimerization of transmembrane peptides
○Toshiki Tsujii1, Hiroyuki Nakao2, Keisuke Ikeda2, Minoru Nakano2 (1. Sch. Pharm., Univ. Toyama, 2. Fac. Pharm. Sci., Univ. Toyama)
[28P-am238]Intracellular drug delivery based on exosomes modified with cell-penetrating sC18 peptides
○Kosuke Noguchi1, Haruka Sumi2, Tomoka Takatani-Nakase3, Ines Neundorf4, Ikuhiko Nakase1,2 (1. Grad. Sch. Sci., Osaka Pref. Univ., 2. Col. Life, Env., Adv. Sci., Osaka Pref. Univ., 3. Sch. Pharm. Pharm. Sci., Mukogawa Women's Univ., 4. Dept. Chem., Cologne Univ.)
[28P-am239]Analysis of photoinactivation of bacterial membrane induced by phenothiazine dyes using electrochemical sensors
○Hisato Kato1, Sachika Miyake1, Kazufumi Masuda1, Takashi Katsu1 (1. Sch. Pharm., Shujitsu Univ.)
[28P-am240]Measurement of solution composition dependence on fluorescence spectrum
Of environmentally sensitive fluorescent probe
○Satoru Ueno1, Muraoka Nannto1, Yoshida Kennta1 (1. The University of Tokushima Institute of Health Biosciences)
[28P-am241S]Development of iron oxide nanoparticle-based theranostics probes targeting tumor-associated macrophages
○Wakana Kataoka1, Kohei Sano1, Masayuki Munekane1, Toshihide Yamasaki1, Takahiro Mukai1 (1. Kobe Pharm. Univ.)
[28P-am242S]Development of a polyoxazoline-based fluorescence imaging probe targeting folate receptor in tumor tissues
○Natsuka Suzuno1, Kohei Sano1, Ling Bao1, Masayuki Munekane1, Tosihide Yamasaki1, Takahiro Mukai1 (1. Kobe Pharm. Univ.)
[28P-am243]Investigation of sulfite radical production in on-set of DSS-induced colitis in mice
○Keiji Yasukawa1, Taiki Sato1, Kota Matsuo1, Masahiro Iwasaki1, Xin Tun2, Susumu Koyama1 (1. Fac. Pharm. Sci., Daiichi Univ. Pharm., 2. Med. Inst. Bioreg., Kyushu Univ.)
[28P-am244]Assessment of biological redox responses to a carbon-ion beam irradiation in the brain of selenium-deficient model mouse
○Ken-ichiro Matsumoto1, Megumi Ueno1, Ichio Aoki2 (1. NIRS, QST, 2. Inst. Quantum Life Sci., QST)
[28P-am245]Dynamics of water molecules in substrate binding to multidrug efflux transporter EmrE by molecular dynamics simulation
○Kazumi Shimono1, Shuichi Miyamoto1 (1. Fac. Pharm. Sci., Sojo Univ.)
[28P-am246S]Crystal Structure of CENP-E motor domain with its inhibitor
○Asuka Shibuya1, Naohisa Ogo2, Jun-ichi Sawada2, Akira Asai2, Hideshi Yokoyama1 (1. Grad. Sch. Pharm. Sci. , Tokyo Univ. Sci., 2. Grad. Sch. Pharm. Sci. , Univ. of Shizuoka)
[28P-am247S]Circadian rhythm and extreame conditions
○Keita Mitsuhashi.1, Soichiro Kitazawa2, Kazuki Terauchi1, Ryo Kitahara1,2 (1. Grad. Sch. Life Sci., Ritsumeikan Univ., 2. Dep. Pharm., Ritsumeikan Univ.)
[28P-am248S]Purification and crystallization of methylthioadenosine phosphorylase
○Makiko Kikuchi1, Takahiro Yamauchi2, Yuuka Yanagida2, Satomi Hasegawa2, Asuka Funaki2, Yasuhito Iizuka2, Masaru Tsunoda1,2 (1. Grad. Sch. Sci.Tech., Iryo Sosei Univ., 2. Fac. Pharm., Iryo Sosei Univ.)
[28P-am249]Structural study of myelin protein zero using NMR
○Masayoshi Sakakura1, Masaki Mori1, Hideo Takahashi1 (1. Grad. Sch. Med. Life Sci., Yokohama City Univ.)
[28P-am250S]A study of the defense effects of white birch sap and 2-hydroxyestradiol 17-sulfate for Caco-2 cell’s injury by hydrogen peroxide
○Shoya Izumi1, Naoto Ishioka1, Yoshihiro Mihara1, Shinji Itoh1, kaori takanashi1 (1. Hokkaido University of Science)
[28P-am251S]Development of a method for estimating the binding mode of xanthine oxidase inhibitors using machine learning.
○Yoshitaka Asanuma1, kentaro kawai1, yukiko karuo1, atsushi tarui1, kazuyuki sato1, masaki omote1 (1. Sci.,setsunan Univ)
[28P-am252S]Prediction model for activity cliff using machine learning
○Shunsuke Tamura1, Tomoyuki Miyao1,2, Kimito Funatsu1,2,3 (1. Grad. Sch. Sci. Tech., NAIST, 2. DSC, NAIST, 3. Grad. Sch. Tec., Univ. Tokyo)
[28P-am253S]Structural comparison between wild-type and mutant CYP2A13 using molecular dynamics simulation
○Sho Hioki1, Tomoki Nakayoshi1, Koichi Kato1,2, Masahiro Hiratsuka3, Eiji Kurimoto1, Akifumi Oda1 (1. Faculty of Pharmacy, Meijo University, 2. Department of Pharmacy, Kinjo Gakuin University, 3. Graduate School of Pharmaceutical Sciences, Tohoku University)
[28P-am254]Identification of the binding mode of an allosteric activator for β-glucocerebrosidase and structural stabilization analyses
○Izumi Nakagome1, Manami Kuwabara1, Noriyuki Yamaotsu1, Tomoki Yoshida1, Shin-ichiro Ozawa1, Shuichi Hirono1 (1. Sch. Pharm., Kitasato Univ.)
[28P-am255]Construction of machine learning model for searching for new integrin αIIbβ3 inhibitor
○Kentaro Kawai1, Mami Tomonou1, Yukiko Karuo1, Atsushi Tarui1, Kazuyuki Sato1, Masaaki Omote1 (1. Setsunan Univ.)
[28P-am256S]Computational studies on the effect of the addition of amino acid species on the conformation of primitive proteins
○Ryota Oyaizu1, Tomoki Nakayoshi1, Koichi Kato1,2, Eiji Kurimoto1, Akifumi Oda1 (1. Faculty of Pharmacy, Meijo University, 2. Department of Pharmacy, Kinjo Gakuin University)
[28P-am257S]Molecular dynamics simulation of human and canine carboxylesterase 2
○Yujiro Nakano1, Tomoki Nakayoshi1, Koichi Kato1,2, Tatsuki Fukami3,4, Miki Nakajima3,4, Eiji Kurimoto1, Akifumi Oda1 (1. Faculty of Pharmacy, Meijo University, 2. Department of Pharmacy, Kinjo Gakuin University, 3. Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 4. WPI Nano Life Science Institute, Kanazawa University)
[28P-am258S]Computational analysis on mechanisms for non-enzymatic peptide bond cleavage of aspartic acid residues using quantum chemical calculations
○Ryo Taguchi1, Tomoki Nakayoshi1, Koichi Kato1,2, Eiji Kurimoto1, Akifumi Oda1 (1. Faculty of Pharmacy, Meijo University, 2. Department of Pharmacy, Kinjo Gakuin University)
[28P-am259S]Molecular dynamics simulations of complexes of androgen receptor and carborane derivatives
○Ryo Kanai1, Koichi Kato1,2, Tomoki Nakayoshi1, Kiminori Ohta3, Yasuyuki Endo4, Eiji Kurimoto1, Akifumi Oda1 (1. Faculty of Pharmacy, Meijo University, 2. Department of Pharmacy, Kinjo Gakuin University, 3. School of Pharmacy, Showa University, 4. Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University)
[28P-am260]A research on N-demethylation of erythromycin by CYP3A4
○Masayuki Hata1, Yukari Kanoh1, Yuuki Takeuchi1 (1. Matsuyama University, College of Pharmaceutical Sciences)
[28P-am261]Development of a new method for constructing core library using predicted bioactivity information
○Yugo Shimizu1, Masanori Osawa1, Kazuyoshi Ikeda1 (1. Keio Univ. Fac. Pharm.)
[28P-am262]Large scale analysis of adenine bioisosteres on kinase selectivity (2)
○Noriyuki Yamaotsu1, Shuichi Hirono1 (1. Sch. Pharm., Kitasato Univ.)
[28P-am263]Development and application of cloud computing system for VHH drug discovery
○Kasahara Hideaki1, Teshima Ryota1, Iwaoka Ryo1, Makiguchi Hiroki1 (1. Mitsui Knowledge Industry co., ltd., Bioscience div., Bioscience dept.)
[28P-am264S]Study on drug dissolution improvement from poly-γ-glutamic acid coated particles containing a poorly soluble drug
○Aoi Kikuchi1, Yuri Ikeuchi1, Yukino Shioya1, Sakiko Nagata1, Shunsuke Nakajima1, Hiraku Onishi1 (1. Hoshi Univ.)
[28P-am265S]Solubility improvement of albendazole by co-crystallization
○Yuko Nakamura1, Hironori Suzuki1, Masataka Itou1, Shuuji Noguchi1 (1. Toho Univ.)
[28P-am266S]Development and evaluation of coprocessing exipients using high sheer granulater
○Taisei Takizawa1, Tomohiro Saeki1, Takayuki Terukina1, Hiromu Kondo1 (1. Grad. Sch. Pharm. Sci., Univ. of Shizuoka)
[28P-am267]Efficient form selection of drug substance using crystal formation energy
○Etsuo Yonemochi1, Daiki Umeda1, Takayuki Furuishi1, Kaori Fukuzawa1 (1. Sch of Pharmacy and Pharmaceutical Sciences, Hoshi University)
[28P-am268]Formulation and manufacturing method to improve the uniformity of red ferric oxide for the wet granulation.
○Kotaro Endo1, Rie Kawabe1, Ayaka Takei1, Keishiro Abe1, Negishi Munehiro1, Yukiya Yamaguchi1, Katsuhide Terada2 (1. Sannova. Production Technology Department., 2. Pharm.,Takasaki University of Health and Welfare.)