Session Details
[28P-am]HPLC・LC/MS・その他
Sat. Mar 28, 2020 9:00 AM - 11:30 AM JST
Sat. Mar 28, 2020 12:00 AM - 2:30 AM UTC
Sat. Mar 28, 2020 12:00 AM - 2:30 AM UTC
[Room P] Event Hall 1F
[28P-am149]The evaluation of lipophilicity of macrocycles congeners using a high-temperature HPLC system
○Kumiko Sakai-Kato1, Kohki Yoshida1 (1. Sch.Pharm., Kitasato Univ.)
[28P-am150]Purification of a potent peptide drug with high purity and high yield using continuous chromatography
○Noritaka Kuroda1, Tomoyuki Okada1, Chiyuki awahara1, Saoko Nozawa1, Eigo Muto1 (1. Kyoto Research Laboratories, YMC CO., LTD.)
[28P-am151]Development and evaluation of novel reversed phase column PFP&C18
○Tomoyasu Tsukamoto1, Norikazu Nagae1 (1. ChromaNik Technologies Inc.)
[28P-am152]Study of reversed phase HPLC condition suitable for oligonucleotides
○Chiaki Aoyama1, Takumi Takano1, Yuko Yui1, Shigenori Ota1, Yoshiro Terasaki1 (1. GL Sciences Inc.)
[28P-am153]Study of sample pretreatment and reversed phase HPLC condition suitable for therapeutic monoclonal antibodies
○yuko yui1, shota miyazaki1, chiaki aoyama1, takumi takano1, shigenori ota1, yoshiro terasaki1 (1. GL Sciences Inc.)
[28P-am154]Development of solid phase extraction sorbent by using water-enriched layer for the extraction of hydrophilic compounds
○Hiroya Murakami1, Takuya Sugiyama1, Yuta Miki1, Yukihiro Esaka2, Yoshinori Inoue1, Norio Teshima1 (1. Aichi Institute of Technology, 2. Gifu Pharm. Univ.)
[28P-am155]A New Concept of End-capping for Reversed Phase Silica Material
○Norikazu Nagae1, Tomoyasu Tsukamoto1 (1. ChromaNik Technologies Inc.)
[28P-am156S]Analysis of nucleic acids using temperature-responsive chromatography
○Miwa Ihara1, Kaichi Yamazaki1, Yutaro Maekawa2, Kenichi Nagase1,2, Hideko Kanazawa1,2 (1. Faculty of Pharmacy, Keio University, 2. Graduate School of Pharmaceutical Sciences, Keio University)
[28P-am157]Condition study of phosphorothioate oligonucleotide separation by high-performance anion-exchange chromatography
○Toshito Kamichika1, Fumiya Nakata1, Akira Kobayashi1 (1. TOSOH)
[28P-am158]HPLC analysis of deAlbumin, a recombinant human albumin with enhanced protein stabilizing activity
○Kiyohiro Toyoda1, Fumiya Nakata1, J. Chern2, Poyi Huang2, Akira Kobayashi1 (1. TOSOH Corp., 2. Albcura Corp.)
[28P-am159]Online IEX-MS Characterization and Monitoring of mAb Charge Heterogeneity Using an Optimized Cation Exchange Resin and Compact TOF Mass Spectrometer
○Hiroko Iwasaki1, Samantha Ippoliti2, Ying Qing Yu2, Matthew A. Lauber2, Henry Shion2 (1. Nihon Waters K.K., 2. Waters Corporation, U.S.A.)
[28P-am160S]Evaluation of retention mechanism of heterocyclic compounds to ion exchange resin
○Kana Inaba1, Satoshi Ohmuro1, Toshiyasu Mikuma1, Kensuke Arai1 (1. Nihon Pharm. Univ.)
[28P-am161S]Retention and molecular-recognition mechanism of molecularly imprinted polymers for promazine derivatives: Contribution of halogen bonding
○Kanae Nishimura1, Tetsutaro Kimachi2, Kiyofumi Inamoto2, Yusuke Kobayashi3, Yoshiji Takemoto3, Jun Haginaka2,4 (1. Grad. Sch. Pharmaceut. Sci., Mukogawa Women's Univ., 2. Sch. Pharm. Pharmaceut. Sci., Mukogawa Women's Univ., 3. Grad. Sch. Pharmaceut. Sci., Kyoto Univ., 4. Inst. Biosci., Mukogawa Women's Univ.)
[28P-am162]Photoprotective effects of photodiode array detector using UV cut-off filter on degradation of photosensitive pharmaceuticals
○Hiroyuki Nishi1, Kohei Kawabata1, Takato Uchikawa2, Keiko Matsumoto2 (1. Dep.Pharm., Yasuda Women's Univ., 2. Shimadzu)
[28P-am163]Determination of sialic acids in biological samples by a high-performance liquid chromatography method with post-column derivatization and fluorometric detection
○Tomomi Izumikawa1, Natsumi Hosoda1, Yuka Komatsubara1, Kanae Mochizuki1, Akiko Toyoda1, Hidenao Toyoda1 (1. Fac. Pharm. Sci. Ritsumeikan Univ.)
[28P-am164S]Microdetermination of keratan sulfates in biological samples with keratanase II and endo-beta-galactosidase
○Yuka Komatsubara1, Kanae Mochizuki1, Yurika Oyama1, Akiko Toyoda1, Tomomi Izumikawa1, Hidenao Toyoda1 (1. Fac. Pharm. Sci. Ritsumeikan Univ.)
[28P-am165]Two-dimensional liquid chromatographic analysis of urea cycle amino acids in human plasma
Yuko Sumida1, Takashi Funatsu2, ○Makoto Tsunoda2 (1. Sch. Pharm. Sci., Univ. of Tokyo, 2. Grad. Sch. Pharm. Sci., Univ. of Tokyo)
[28P-am166]Separation of inorganic anions by HPLC using mobile phase with phosphomolybdate
○Tomoko Kemmei1, Shuji Kodama2, Atsushi Yamamoto3, Yoshinori Inoue4, Kazuichi Hayakawa5 (1. Toyama Institute of Health, 2. School of Science, Tokai University, 3. College of Bioscience and Biotechnology, Chubu University, 4. Faculty of Engineering, Aichi Institute of Technology, 5. Institute of Nature and Environmental Technology, Kanazawa University)
[28P-am167S]Development of a HPLC-UV method for the quantification of baloxavir marboxil and its metabolites in human milk.
○Kana Chiba1, Tomohiko Tairabune1, Hiroaki Takahashi1, Asaka junichi1, Takeshi Chiba2, Kenzo Kudo1 (1. Department of Clinical Pharmacy,Division of Clinical Pharmaceutics and Pharmacy Practice,School of Pharmacy,Iwate Medical University, 2. Department of Clinical Pharmaceutics,Faculty of Pharmaceutical Sciences,Hokkaido Kagaku University)
[28P-am168]Analysis of degradation of unsaturated fatty acids causing aging odor by Diphenyl-1-pyrenylphosphine
○Keita Saito1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)
[28P-am169S]Development of online automated analysis of steroid hormones by in-tube SPME/LC-MS/MS
○Takashi Hitomi1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu Univ.)
[28P-am170S]Analysis of formation of advanced glycation end products AGEs by LC-MS/MS method
○Jumpei Tada1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)
[28P-am171S]Analysis of photolysis of 9-hexadecenoic acid causing aging odor by fiber SPME/GC-MS
○Kaho Takebe1, Ayaka Nishihara1, Keita Saito1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)
[28P-am172S]Evaluation of CYP enzyme inhibitory effect of polyphenol compounds in foods by simple fluorescence assay
○Nanami Yoshioka1, Keita Saito1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)
[28P-am173S]Evaluation of CYP enzyme inhibitory effect of α-Pyrrolydinoalkylphenone by simple fluorescence assay
○Shuuhei Tsuji1, Hirokazu Ishii1,2, Keita Saito1, Hiroyuki Kataoka1 (1. School of Pharmacy,Shujitsu University, 2. Forensic Sci. Lab., Okayama Pref. Police H.Q.)
[28P-am174S]Analysis of inhibition of 9-hexadecenoic acid degradation causing body odor by antioxidant components by fiber SPME/GC-MS
○Miyuki Oshita1, Kanako Otani1, Keita Saito1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)
[28P-am175S]Characteristic of produced compound by interaction of antioxidant with metal ion
○Rie Manabe1, Haruna Abe1, Yuki Matsumoto1, Yusuke Iwasaki1, Junzo Kamei1 (1. Hoshi univ.)
[28P-am176S]Comparison in quantification of selenocyanate and thiocyanate between HPLC-Fluorescence Detector and HPLC-inductively coupled plasma mass spectrometer
○Aphinan Hongprasit1, Yusuke Okamoto1, Yu-ki Tanaka1, Noriyuki Suzuki1, Toshihiko Toida1, Yasumitsu Ogra1 (1. Grad. Sch. Pharm. Sci., Chiba Univ.)
[28P-am177]Direct enantioseparation of mandelic acid by chiral HPLC with a mobile phase containing a small amount of cyclodextrin
Yuri Watanabe1, Ikko Mikami1, Atsushi Yamamoto2, Sen-ichi Aizawa3, Atsushi Taga4, Naoki Mochizuki5, Yoshimi Ishihara1, ○Shuji Kodama1 (1. Sch. Sci., Tokai Univ., 2. Dep. Biol. Chem., Coll. Biosci. Biotechnol., Chubu Univ., 3. Grad. Sch. Sci. Engineer., Univ. Toyama, 4. Dep. Pharm., Kindai Univ., 5. Yokohama Univ. Pharm.)
[28P-am178S]Optimization of solid-phase extraction conditions of a target drug in serum with subsequent a practical HPLC analysis for in-hospital implementation of TDM of various medicinal drugs
○Kento Takekoshi1, Yukiko Moriiwa1, Go Morikawa2, Atsushi Shoji1, Akio Yanagida1 (1. Sch. Pharm., Tokyo Univ. Pharm. and Life Sci., 2. Pharm., Hokushin Gen. Hosp.)
[28P-am179]INCREASING THE THROUGHPUT OF CANNABINOID PROFILING AND POTENCY DETERMINATION USING CHROMATOGRAPHIC GEOMETRIC SCALING PRINCIPLES
○Keisuke Fukazawa1, Futoshi Sato1, Tatsuya Ezaki1, Catharine Layton2, Andrew Aubin2 (1. Nihon Waters K.K., 2. Waters Corporation)
[28P-am180S]Relationship between phospholipidosis induction potential molecular interaction between drug and polar groups of phospholipid
○Yoshie Iwakuma1, Yuko Imajyo2, Haruka Okamoto2, Ryohei Hamaguchi2, Yukihiro Kuroda2 (1. Grad. Sch. Pharm. Sci., Mukogawa Women’s Univ. , 2. Sch. Pharm. Sci., Mukogawa Women’s Univ. )
[28P-am181]Liquid chromatography analysis of keto acids with 2,4-dinitrophenylhydrazine derivatization followed by excess reagent scavenging
○Ryoko Tomita1, Rihono Sato1, Emiko Kaga1, Nao Nishijyo1, Tadashi Hayama1, Toshihiro Fujioka1 (1. Faculty of Pharmaceutical Sciences, Fukuoka Univ.)
[28P-am182S]Determination of glutathione in aging mouse by LC/MS/MS
○Hitomi Matsumoto1, Kanae Funato1, Kanako Yabuki1, Chinatsu Ando1, Yusuke Iwasaki1, Junzo Kamei1 (1. Hoshi Univ.)
[28P-am183S]Changes of neurotransmitters in mouse brain by resveratrol administration
○Mako Miyazawa1, Hinano Ino1, Saki Yamada1, Yusuke Iwasaki1, Junzo Kamei1 (1. Hoshi Univ.)
[28P-am184S]Effect of neurotransmitters in mouse brain of exposed heat-not-burn product
○Mami Okumura1, Yuka Iwamoto1, Hayato Takayama1, Yusuke Iwasaki1, Junzo Kamei1 (1. Hoshi Univ.)
[28P-am185S]Determination of pretreatment method of amyloid β peptide aggregates in brain using LC-MS/MS with 13C-labeled internal standard
○Miki Takahashi1, Hiroaki Komatsu2, Paul Axelsen2, Koichi Inoue1 (1. Ritsumeikan University Graduate School of Pharmacy, 2. University of Pennsylvania School of Medicine)
[28P-am186]Analysis of Extractables and Leachables using GC/MS - Part II-
○Takeshi Otsuka1, Chika Nogami1, Sadao Nakamura1 (1. Agilent Technologies Japan, Ltd.)
[28P-am187]Analysis of extractables and leachables using LC/MS - Part II -
○Chika Nogami1, Seiya Tanaka1, Takeshi Otsuka1, Hirokazu Sawada1 (1. Agilent Technologies Japan, Ltd.)
[28P-am188]A novel caged Cookson-type reagent toward a practical vitamin D derivatization method for mass spectrometric analyses
Masahiko Seki1, Makoto Sato1, Masaki Takiwaki2,3, Koji Takahashi2,4, Kikutani Yoshikuni2,4, Fumio Nomura3, Mamoru Satoh3, Yutaka Kuroda4, ○Seketsu Fukuzawa2,4 (1. Tokuyama, 2. JEOL, 3. Chiba Univ. Hosp., 4. Faculty of Technol., TUAT)
[28P-am189]Time course analysis of equol-conjugated metabolites in human blood and urine after administration of kinako
○Aki Obara1, Mizuki Kinoshita1, Kaori Hosoda1, Kazuo Ishii1 (1. Faculty of Health Sciences, Kyorin Univ.)
[28P-am190]Evaluation of proton-affinitive derivatives in LC-ESI-MS/MS analysis of C21-steroids and its application to quantitative determination
○Toshinori Nakakita1, Sachiko Komatsu2, Ayaka Tanno2, Tomoaki Hattori2, Shouko Taguchi1, Ayami Azumagawa1, Ken-ichi Ohno2, Fujimura Tsutomu2, Kouwa Yamashita1 (1. Yokohama Univ. of Pharm., 2. Tohoku Med. Pharm. Uni.)
[28P-am191]Development of proton-affinitive derivatization method using quinolinecarboxylic acid reagents and determination of steroids by LC-ESI/MS/MS
○Sachiko Komatsu1, Ken-ichi Ohno1, Kentarou Shibata1, Kazuya Hosoya1, Tsutomu Fujimura1, Yuta Honma2, Asako Nishimura2, Toshinori Nakakita2, Kouwa Yamashita2 (1. Tohoku Med. Pharm. Uni., 2. Yokohama Uni. Pharm.)
[28P-am192S]Influence of N-terminal amino acid sequence on expression efficiency of the proteins concatenating internal standard peptides for targeted proteomics
○Ayano Mori1, Tomohiro Kohata2, Ryotaro Yagi2, Yui Kaneko1, Takeshi Masuda1,2,3, Shingo Ito1,2,3, Sumio Ohtsuki1,2,3 (1. Sch. Pharm., Kumamoto Univ., 2. Grad. Sch. Pharm. Sci., Kumamoto Univ., 3. Grad. Fac. Life Sci., Kumamoto Univ.)
[28P-am193]Analysis of anti-influenza drugs in tap water using multi-mode column
○Osamu Sakata1, Hiroki Watanabe1, Hirotaka Seino1, Ikue Oosaka1, Terumitsu Yoshida1, Rie Ishii1 (1. Saitama Prefectural Institute of Public Health)
[28P-am194]Sample-multiplexing LC/ESI-MS/MS assay for plasma 17α-hydroxyprogesterone by derivatization with four analogous Girard-type reagents
Miki Kamemura1, Shoujiro Ogawa1, ○Tatsuya Higashi1 (1. Fac. Pharm. Sci., Tokyo Univ. Sci.)
[28P-am195S]Establishment of lesion-site specific proteomics by application of Laser Microdissection to FFPE sections: The analysis of pathological changes in protein expression level in BDL mice
○Takumi Handa1, Yasuo Uchida1,2, Hayate Sasaki2, Takuya Usui1,2, Tetsuya Terasaki1,2 (1. Fac. Pharm. Sci., Tohoku Univ., 2. Grad. Sch. Pharm. Sci., Tohoku Univ.)
[28P-am196]ANALYTICAL QUALITY BY DESIGN FOR THE ANALYSIS OF FORMOTEROL, BUDESONIDE, AND ITS RELATED COMPOUNDS
○Yusuke Asahi1, Shunya Sasaki1, Hiroko Iwasaki1, Fadi Alkhateeb2, Paul Rainville2 (1. Nihon Waters, 2. Waters Corp.)
[28P-am197]SmartMS system optimized for routine monitoring of biopharmaceutical Products
○Shota Nakamura1, Henry Shion2, Ying Qing Yu2, Weibin Chen2, Nilini Ranbaduge2, Ximo Zhang2, Corey Reed2, William Alley2, Robert Birdsall2 (1. Nihon Waters K.K., 2. Waters Corporation)
[28P-am198]Determination of abiraterone and its metabolites in human serum in LC/MS using solid-phase extraction
○Hiromi Kanji1, Shizuyo Horiyama2, Jun Haginaka1,2 (1. Sch. Pharm. Pharmaceut. Sci., Mukogawa Women's Univ., 2. Inst. Biosci., Mukogawa Women's Univ.)
[28P-am199S]PRM analysis of circadian phosphorylation changes on a postsynaptic protein gephyrin
○Saki Hasegawa1, Tsai Yuan-Chen2, Ayaka Goto1, Yasuhiro Hirano1, Shiva Tyagarajan2, Susumu Imanishi1 (1. Faculty Pharm., Meijo Univ., 2. Univ. Zurich)
[28P-am200S]Development of dual solid phase extraction and LC-MS/MS for screening assay of nitrosoamines in medicine products
○Shoko Yagi1, Yoshio Muguruma2, Miki Takahashi2, Koichi Inoue1,2 (1. College of Pharmaceutical Sciences, Ritsumeikan University, 2. Graduate School of Pharmaceutical Sciences, Ritsumeikan University)
[28P-am201S]Procreation of 13C stable isotope avermectin B1a/B1b for LC-MS/MS from Streptomyces avermitilis
○Kodai Beppu1, Mizuki Okabayashi1, Yoshio Muguruma2, Daichi Saito3, Shuichi Harada4, Koichi Inoue1,2 (1. School of Pharmaceutical Sciences, Ritsumeikan University, 2. Graduate School of Pharmaceutical Sciences, Ritsumeikan University, 3. Graduate School of Life Sciences, Ritsumeikan University, 4. Hayashi Pure Chemical Ind.,Ltd)
[28P-am202S]Development of air assisted dispersive liquid-liquid microextraction with solidification of the floating organic droplet for the analysis of methamphetamine in urine
○Futaba Ikeda1, Satoshi Ohmuro1, Toshiyasu Mikuma1, Kensuke Arai1 (1. Nihon pharm.Univ.)
[28P-am203S]Evaluation of analytical conditions for organic compounds using a DART Orbitrap mass spectrometer Exactive Plus.
○Masaki Hoshino1, Ema Ueno1, Ryuji Yamashita2, Masahiko Tachi3, Ken-ichi Harada1,2, Susumu Imanishi1 (1. Faculty Pharm., Meijo Univ., 2. Grad. Sch. Environ. Human Sci., Meijo Univ., 3. Aichi Pref. Inst. Public Health)
[28P-am204]Purification of a flavanonol, phenylcoumarans and flavonolignans in Silybum marianum using high-speed countercurrent chromatography
○Kazumasa Zaima1, Naoki Harikai1, Kazufusa Shinomiya1 (1. School of Pharmacy, Nihon University)
[28P-am205]Development of mitochondria metabolite analytical method using mitochondrial localized photoaffinity probe
○Hajime Mizuno1, Natsumi Tanaka1, Takamitsu Sasaki1, Teppei Minami1, Eiji Sugiyama1, Toshimasa Toyo'oka1, Koichi Yoshinari1, Kenichiro Todoroki1 (1. Sch. Pharm. Sci., Univ. of Shizuoka)
[28P-am206]Development of circulating tumor cell detection method using capillary electrophoresis.
○Tetsushi Yamamoto1, Kuniko Mataura1, Atsushi Taga1 (1. Kindai Univ.)
[28P-am207]Synthesis and evaluation of the ferulic acid derivatives as the MALDI matrix for proteome analysis
○Yosuke Kato1, Naoya Kitada1, Yusuke Suzuki1, Hirotaka Mizushima1, Maiyan Xuan1, Jun Takayama1, Mari Okazaki1, Takeshi Sakamoto1, Narumi Hirosawa2, Yasushi Sakamoto2 (1. Pharm. Sci., Josai Univ, 2. Saitama Medical Univ)