Session Details
[28Q-pm]生薬学・天然物化学④
Sat. Mar 28, 2020 2:00 PM - 4:30 PM JST
Sat. Mar 28, 2020 5:00 AM - 7:30 AM UTC
Sat. Mar 28, 2020 5:00 AM - 7:30 AM UTC
[Room Q] New Hall 1F
[28Q-pm092S]Synthesis of compounds derived from sponge Terpios sp.
○satoshi mukai1, Naohiro ooshima1, noriyasu hada1 (1. Grad. Sch. pharm. sci., Tokyo University of Sciences .)
[28Q-pm093S]Elucidation of the constituents in Magnolia Flower influenced by seasonal change (3)
○Minami Iwata1, Naohiro Oshima1, Noriyasu Hada1 (1. Pharm. Sci., Tokyo univ of sci.)
[28Q-pm094S]Elucidation of seasonally variable constituents in Persimmon Calyx (2)
○Emi Katsumi1, Naohiro Oshima1, Natsuko Kagawa2, Hitoshi Ohara2, Noriyasu Hada1 (1. Grad. Sch. Pharm. sci., Tokyo Univ. of Sci., 2. Center for Environment, Health and Field Sci., Chiba Univ.)
[28Q-pm095S]Changes in the extraction amount of flavonoids derived from Scutellaria Root by combining with crude drugs
○Moe Takeda1, Naohiro Oshima1, Noriyasu Hada1 (1. Pharm. Sci., Tokyo Univ of Sci.)
[28Q-pm096S]Elucidation of seasonally variable constituents in Zanthoxylum piperitum
○Satoko Okouchi1, Naohiro Oshima1, Naoko Masumoto2, Yuzo Nishizaki2, Naoki Sugimoto2, Kyoko Sato2, Noriyasu Hada1 (1. Grad. Sch. Pharm. Sci., Tokyo Univ of Science., 2. Nationai Institute of Health Sciences)
[28Q-pm097S]Chemical components of Ranunculaceae plants (35)Steroidal derivatives from the whole plants of Helleborus niger, and their cytotoxicity and apoptosis inducing activity
○Mina Inomata1, Akihito Yokosuka1, Tomoki Iguchi1, Yoshihiro Mimaki1 (1. Tokyo University of Pharmacy and Life Sciences)
[28Q-pm098]Structure Revision of Five Natural Sterols
○Yasunori Yaoita1, Koichi Machida1 (1. Pharm. Sci. Tohoku Med. Pharm. Univ.)
[28Q-pm099]New Ergostane-type Steroids from Fruiting Bodies of Pleurotus cornucopiae
○Takashi Kikuchi1, Shota Morikawa1, Daichi Anami1, Takeshi Yamada1, Tomoya Hirano1 (1. Osaka University of Pharmaceutical Sciences)
[28Q-pm100S]Steroidal glycosides from the underground parts of Agapanthus africanus and their cytotoxic activity
○Akihiro Nagata1, Tomoki Iguchi1, Yoshihiro Mimaki1 (1. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)
[28Q-pm101S]Secondary metabolites isolated from four strains of Cordyceps fungus
○Mayu Nishigawa1, Yoneyama Tatsuro1, Abdelsamed Elsharmy1, Ban Sayaka2, Noji Masaaki1, Umeyama Akemi1 (1. Pharm.Sci.,Tokushima Bunri Univ., 2. Medical Mycology Research Center,Chiba Univ.)
[28Q-pm102]Structure elucidation of a new quinolone and an acridone dimer from Glycosmis cochinchinensis and the inhibitory effect of human cancer cell proliferation of the isolated compounds
○Chihiro Ito1, Mami Goto1, Takuya Matsui2, Masataka Itoigawa3, Sivabalan Shanmugam4 (1. Faculty of Pharmacy, Meijo Univ., 2. Aichi Medical Univ., 3. Tokai Gakuen Univ., 4. Annamalai Univ.)
[28Q-pm103]Study on the absolute conformation of tetrahydro-β-carbolin-5-on having a substituent at C-3
○Tadayoshi Onozawa1, Sawa Takagi1, Noriyuki kogure1, Mariko kitajima1, Hiromitsu Takayama1 (1. Grad. Sch. Pharm. Sci., Chiba Univ.)
[28Q-pm104S]Development of terpenoid alkaloid-like compounds library based on diversity-enhanced extracts
○Shizuka Nakano1, Kosuke Kawai1, Akihiro Sugawara1, Yoshiteru Oshima1, Haruhisa Kikuchi1 (1. Grad. Sch. Pharm. Sci., Tohoku Univ.)
[28Q-pm105]Design and synthesis of β-carboline alkaloids using a one-pot Pictet-Spengler reaction and their biological activity
○Dya Fita Dibwe1, Hirotoshi Fuda1, Yusuke Yamamoto1, Rojeet Shrestha1, Hitoshi Chiba2, Shu Ping Hui1 (1. Faculty of Health Sciences, Hokkaido University, 2. Department of Nutrition, Sapporo University of Health Sciences)
[28Q-pm106S]Biological evaluation of aporphine-type alkaloid, nuciferine, isolated from Nelumbo nucifera and its derivatives
○Sayaka Ino1, Seikou Nakamura1, Tomoko Matsumoto1, Kaori Ryu1, Yukako Katsurada1, Souichi Nakashima1, Hisashi Matsuda1 (1. Kyoto Pharmaceutical University)
[28Q-pm107S]Biological evaluation of carbazoles and its derivatives from Bergera koenigii (Rutaceae)
○Yukino Notsu1, Seikou Nakamura1, Tomoko Matsumoto1, Tomohiro Shimada1, Souichi Nakashima1, Hisashi Matsuda1 (1. Kyoto Pharmaceutical University)
[28Q-pm108]Synthesis and anti-hyphae formation property of tetramic acid derivatives against Candida albicans
○Hitoshi Kamauchi1, Taishi Seki1, Yu Kimura1, Mikoto Ushiwatari1, Koichi Takao1, Yoshiaki Sugita1 (1. Faculty of Pharmaceutical and sciences Josai University)
[28Q-pm109]The chemical structure of novel macrolide produced by a marine alga-derived fungus
○Takeshi Yamada1, Haruka Kogure1, Takashi Kikuchi1 (1. Osaka University of Pharmaceutical Sienses)
[28Q-pm110]Synthesis of fluorinated analogue of RA-VII, an antitumor cyclopeptide. Part III.
○yuki yoshida1, chihiro nagaishi 1, tomoyo hasuda1, yukioh hitotsuyanagi1 (1. Tokyo University of Pharmacy and Life Sciences)
[28Q-pm111S]New diterpenoid alkaloids from Aconitum japonicum subsp. subcuneatum (9)
○Yunimi Ota1, Yumi Matsuzawa1, Hiroshi Yamashita1, Koji Wada1 (1. Fac. Pharm. Sci., Hokkaido Univ. Sci.)
[28Q-pm112S]New C19-diterpenoid alkaloids from Delphinium elatum (9)
○Nozomi Doi1, Wataru Nakano1, Nana Hanawa1, Hiroshi Yamashita1, Koji Wada1 (1. Fac. Pharm. Sci., Hokkaido Univ. Sci.)
[28Q-pm113S]One-pot Synthesis and biological evaluation of 7-evodiamine analogs as TRPV1 agonists
○Takahiro Furuta1, Yusuke Kawabata1, Utugi Takako1, Tatuya Sirahata1, Shunsuke Nakamori1, Satoko Kagawa(Tanaka)2, Hideto Jinno3, Yosinori Kobayasi1 (1. Sch.of Pharm,Kitasato Univ., 2. Yokohama Univ of Pharm., 3. Sch.of Pharm,Meijo Univ.)
[28Q-pm114]Antioxidant activity of natural product of microbial origin and its life-extending effect on C. elegans
○Satoshi Takamatsu1, Saho Ikeda1, Nozomi Ito1, Shiori Sato1, Riku Yamanaka1, Keiko Ishino1, Kayo Yasuda2, Naomi Ishii2, Kazuyoshi Kawazoe1 (1. Sch. Pharm. Showa Univ., 2. Sch. Health Stud. Tokai Univ.)
[28Q-pm115]Effects of lepidium meyenii WALP (maca) on growth of rats
○Tamaki Jikyo1 (1. Department of food and nutrition, Osaka Yuhigaoka Gakuen College)
[28Q-pm116]Functionality of Angelica acutiloba leaf
○Hiromi Shimizu1, Akiko Shuto1 (1. Nara Pre. Ins. Ind. Dev.)
[28Q-pm117S]Synthesis of Butenolides from Thai Medicinal Plant “Melodorum” and Their Biological Evaluation as Melanogenesis Inhibitors
○Yuri Shiotani1, Fumihiro Ishikawa1, Toshio Morikawa2, Kiyofumi Ninomiya2, Genzoh Tanabe1,2 (1. Fac. Pharm, Kindai Univ., 2. Pharm. Res. Tech. Inst, Kindai Univ.)
[28Q-pm118S]The effects of ephedrine alkaloids in Ephedra Herb on forced swimming test and pentobarbital sleep test in mice
○Shunosuke Tanigaki1, Soya Ono1, Kohei Watanabe1, Xuedan Huang1,2, Sumiko Hyuga2, Hiroaki Takemoto2,7, Tadatoshi Yamashita3, Jinwei Yang3, Nahoko Uchiyama4, Masashi Hyuga4, Naohiro Oshima5, Yoshiaki Amakura6, Takashi Hakamatsuka4, Yukihiro Goda4, Hiroshi Odaguchi2, Toshihiko Hanawa2, Yoshinori Kobayashi1,2 (1. Sch. of Pharm, Kitasato Univ., 2. Oriental Med. Res. Center, Kitasato Univ., 3. TOKIWA Phytochemical Co., LTD, 4. NIHS, 5. TUS, 6. Col. of Pharm. Sci., Matsuyama Univ., 7. Faculty of Pharm., Toho Univ.)
[28Q-pm119]Evaluation of clinically used agents using an infected cell model of Mycobacterium avium complex
○Kanji Hosoda1, Nobuhiro Koyama1, Hiroshi Tomoda1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ.)
[28Q-pm120]New activity of ophiobolin A produced by endophytic fungus Bipolaris sp. associated with Datura metel
○Shoji Maehara1, Masatoshi Ohnishi1, Tetsuya Nakamura1, Chihiro Yamane1, Chinami Kitamura1, Kengo Banshoya1, Tetsuro Tanaka1, Atsuko Inoue1, Toshiyuki Hata1 (1. Pharm. Pharm. Sci., Fukuyama Univ.)
[28Q-pm121]Effect of aerial part of Kummerowia striata on the stagnant blood syndrome
○Shui Aoki1, Yuri Makino1, Chinami Sasaki1, Fumika Kitagawa1, Hisae Oku1 (1. Mukogawa Woman's Univ.)
[28Q-pm122]Synthesis and biological evaluation of retinoid X receptor agonists inspired by neolignans from Magnolia obovata
○Ken-ichi Nakashima1, Eiji Yamaguchi2, Chihaya Noritake1, Yukari Mitsugi2, Mayuki Goto2, Takao Hirai1, Akichika Itoh2, Makoto Inoue1 (1. Sch. Paharm., Aichi Gakuin Univ., 2. Gifu Pharmaceutical Univ.)
[28Q-pm123]Study of molecular targets of dinapinone A which inhibits neutral lipid accumulation in mammalian cells
○Keisuke Kobayashi1, Souma Okuhata1, Hiroshi Tomoda1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ.)
[28Q-pm124]Identifcation of nerve growth factors with chemical pulldown by arecaidine from Areca catechu
○Yoshiyuki Hirata1, Tsutomu Sasaki3, Shinichi Uesato2,1, Yasuo Nagaoka2, Makio Shibano1, Masahiko Taniguchi1 (1. Osaka University of Pharmaceutical Science, 2. Department of Life Science and Biotechnology, Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3. Department of Neurology, Graduate School of Medicine, Osaka University)
[28Q-pm125S]Search for anti-tumor components from Angelica Dahurica Root against human ovarian cancer KOC7C cell line. 2nd.
○Yui Sunouchi1, Yumi Nishiyama1, Nobukazu Shitan1, Tamotsu Sudo2 (1. Kobe Pharm. Univ., 2. Hyogo Cancer Center)
[28Q-pm126]Structure and activity of differentiation factor of Dictyostelium slime mold
○Yoshiaki Takaya1, Salma Zulqaida1, Akiko Oohata2, Kei Inouye3, Tamao Saito4 (1. Fac. Pharm., Meijo Univ., 2. Kansai Med. Univ., 3. Grad. Sch. Sci., Kyoto Univ., 4. Fac. Sci. Tech., Sophia Univ.)
[28Q-pm127]Investigation of degradation for the compound contained in the roots of Rhubarb by Aspergillus oryzae
○Daigo Wakana1, Kumiko Mine1, Hisashi Takeda1, Takashi Yaguchi2, Tomoo Hosoe1 (1. Department of Bioreguratory science, 2. Medical mycology research center, Chiba university)
[28Q-pm128S]Search for natural product on actinomycetes that have toxicity to TRAIL-resistant cancer cells
○Hiroshi Ichikawa1,2, Yasumasa Hara1,2, Midori A. Arai1,2, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Plant Mol. Sci.Cent., Chiba Univ.)
[28Q-pm129S]Search for natural compounds that suppress HBO1 expression
○Tomomi Nakano1, YoungSook Yun1, Megumi Umetsu 1, Nobuko Matsushita 1, Katsunori Miyake2, Hiroyuki Fuchino3, Nobuo Kawahara3, Shigeru Yanagi1, Yuji Takahashi1, Hideshi Inoue1 (1. Sch. Life Sci., Tokyo Univ. Pharm. Life Sci., 2. Sch. Pharm., Tokyo Univ. Pharm. Life Sci., 3. NIBIOHN)
[28Q-pm130S]Inhibitory effects of the extracts of herbal medicines on advanced glycation end products (AGEs) formation
○Asuka Noguchi1, Akihito Yokosuka1, Yosihiro Mimaki1 (1. Tokyo University of Pharmacy and Life Sciences)
[28Q-pm131S]Inhibitory effects of the chemical components from Artemisiae Folium on advanced glycation end products (AGEs) formation and accumulation of autophagosome
○Ayaka Ohsawa1, Akihito Yokosuka1, Yoshihiro Mimaki1 (1. Tokyo University of Pharmacy and Life Sciences)
[28Q-pm132S]The effect of nectriatide derivatives on antifungal activity of amphotericin B
○Yukino Sato1, Kenichiro Nagai1, Keisuke Kobayashi1, Takashi Fukuda2, Hiroshi Tomoda1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ., 2. Fac. Agric. Kinki Univ.)
[28Q-pm133]The screening of crude drug based on the inhibitory effect against toxicity of oxidized polyunsaturated fatty acid-modified amyloid.
○Shinsuke Hisaka1, Yuri Suzuki1, Maho Ishiduka1, Himawari Satsuki1, Saki Masuda1, Mitsuhiko Nose1 (1. Meijo Univ.)
[28Q-pm134S]New Sterol O-acyltransferase (SOAT) inhibitors produced by the fungus Volutella citrinella BF-0440
○Elyza Aiman Azizah Nur1, Ai Amagai2, Keisuke Kobayashi1, Taichi Ohshiro1, Hiroshi Tomoda1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ., 2. Sch. of Pharm., Kitasato Univ.)
[28Q-pm136]Screening of amyloid-beta binding compounds in the plant extracts using STD-NMR method
○Koji Uwai1, Hiroyuki Kumeta2,3, Taro Imamaeda4, Masahiro Kuragano1, Chigusa Seki1, Hiroto Nakano1, Tomoyasu Aizawa2,3, Kiyotaka Tokuraku1 (1. Gurad. Sch. Eng. Muroran Inst. Tech., 2. Fac. Adv. Life Sci. Hokkaido Univ., 3. GI-CoRE Hokkaido Univ., 4. Dep. Eng. Muroran Inst. Tech.)
[28Q-pm137]Identification of antitrypanosomal factors in a citrus cultivar
○Masayuki Nakanishi1, Mami Hino1, Morio Yoshimura1, Yoshiaki Amakura1, Hiroshi Nomoto1 (1. Sch. Pharm. Sci., Matsuyama Univ.)
[28Q-pm138]Search for new bioactive natural products from pathogenic actinomycetes of the genus Nocardia under coculture with mammalian cells.
○Yasumasa Hara1,2, Midori A. Arai1,2, Takashi Yaguchi3, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Med. Myc. Res. Cent., Chiba Univ.)
[28Q-pm139S]Search for new natural products by co-culture method that mimics the growth environment of microorganisms
○Mareno Chiba1,2, Yasumasa Hara1,2, Masami Ishibashi1,2 (1. Grad.Sch.Pharm.Sci.,Chiba Univ., 2. Plant Mol.Sci.Cent.,Chiba Univ.)
[28Q-pm140S]Search for bioactive natural products from drug resistant strains of pathogenic Nocardia sp.
○Itsuki Ebihara1,2, Midori A. Arai1,2, Yasumasa Hara1,2, Takashi Yaguchi3, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Med. Myc. Res. Cent., Chiba Univ.)
[28Q-pm141S]Synergic effects between crude drugs and metformin on cytotoxic activity
○Takuro Nara1, Masayuki Aoki1, Yukiko Matsuo1, Yoshihiro Mimaki1 (1. School of Pharmacy,Tokyo University of Pharmacy and Life Sciences)
[28Q-pm142]Screening for protein tyrosine phosphatase 1B inhibitors from Indonesian edible plants
○Hiroyuki Yamazaki1, Magie M. Kapojos2, Delfly B. Abdjul3, Takahiro Chida1, Akiho Yagi1, Ryuji Uchida1 (1. Tohoku Med. Pharm. Univ., 2. University of Pembangunan Indonesia, 3. North Sulawesi Research and Development Agency)
[28Q-pm143]Protein tyrosine phosphatase 1B inhibitory sesquiterpenes from Petasites japonicas collected at Miyagi
Hiroyuki Yamazaki1, Hayato Tsuge1, Takahiro Chida1, Nozomi Ishii1, Karin Omori1, Yasuhiro Takahashi1, Yuta Yagisawa1, Rei Endo1, ○Ryuji Uchida1 (1. Tohoku Med. Pharm. Univ.)
[28Q-pm144S]Study on antifungal antibiotics produced by actinomycete strain TMPU-A0287
○Yuga Yamaguchi1, Akiho Yagi1, Hiroyuki Yamazaki1, Ryuji Uchida1 (1. Tohoku Med. Pharm. Univ.)
[28Q-pm145]Screening of small molecular modulators targeting the 14-3-3 protein-protein interactions from several fungi
○Kai Ichikawa1, Tomoaki Shiino1, Hiroki Takamura1, Katsuyuki Nakashima2, Masami Tanaka2, Ikuko Okamoto2, Yoshinori Asakawa1, Hiromichi Hiromichi Kenmoku1 (1. Inst. Pharmacog., Tokushima Bunri Univ., 2. Pharm. Sci., Tokushima Bunri Univ.)
[28Q-pm146]Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants
○Daisuke Nakano1, Kenji Ishitsuka2, Fumika Kanayama1, Aya Sato1, Ryota Tsuchihashi1, Masafumi Okawa1, Kazuo Tamura3, Jyunei Kinjyo1 (1. Fukuoka Univ., 2. Kagoshima Univ., 3. Fukuoka University)
[28Q-pm147]Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants
Daisuke Nakano1, ○Kanta Noguchi1, Kenji Ishitsuka2, Aya Sato1, Ryota Tsuchihashi1, Masafumi Okawa1, Kazuo Tamura3, Jyunei Kinjyo1 (1. Fukuoka univ., 2. Kagoshima univ., 3. Fukuoka University)
[28Q-pm148]Isolation of new glisoprenins from the marine-derived Aspergillus polyporicola BFM-0088, as new potentiators of amphotericin B activity against Candida albicans
○Satoshi Ohte1,2, Natsuki Ibuki2, Shun Utsuki1, Keisuke Kobayashi1,2, Hiroshi Tomoda1,2 (1. Grad. Sch. Pharm. Sci., Kitasato Univ., 2. Sch. Pharm., Kitasato Univ.)
[28Q-pm149S]Isolation of a novel diketopiperazine from the marine-derived fungus BFM-0085, as an inhibitor of BMP induced osteoblastic differentiation.
○Takehiro Shiokawa1, Satoshi Ohte1,2, Hiroshi Tomoda1,2 (1. Sch. Pharm., Kitasato Univ., 2. Grad. Sch. Pharm. Sci., Kitasato Univ.)
[28Q-pm150]Inhibitory activity of a fungal metabolite oosporein against Cap-snatching reaction of influenza virus
○Nobuhiro Koyama1,2, Aya Niijima1, Shino Masuo1, Haruka Mio1, Yoshio Shibagaki1,2, Mitsuru Okuwaki1,2, Hiroshi Tomoda1,2 (1. Sch. Pharm. Kitasato Univ., 2. Grad. Sch. Pharm. Sci., Kitasato Univ.)
[28Q-pm151]Evaluation of anti-androgenic effect of oenothera biennis
○Hiroaki Tsuzuki1, Naoko Watanabe1, Katsumasa Okamura1 (1. REVE21 Co., Ltd )
[28Q-pm152S]Search for RHEI RHIZOMA constituents with inhibitory activity on cortisol level
○Nanami Kase1, yuki nakamura1, tsuyoshi ueki1, naoko kuwabara1, yukiko matsuo1, yoshihiro mimaki1, eichi tachikawa1, haruki yamada1 (1. Tokyo University of Pharmacy and Life Sciences)
[28Q-pm153S]Glycation inhibitory active components of corn silk
○Aiko Sano1, Ryuichiro Suzuki1, Masashi Kitamura1, Yoshiaki Shirataki1 (1. Faculty of Pharm., Josai Univ.)
[28Q-pm154]Characterization of lactase phlorizin-hydrolase activities toward natural product glycosides
Shiho Sogawa1, Jun'ichi Hiwatari1, ○Kazuyoshi Terasaka1, Toshiaki Makino1 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ.)
[28Q-pm155S]Production and structure determination of a new compound isolated from Isaria tenuipes NBRC111630
○Marina Sakurai1, Taturo Yoneyama1, Sayaka Ban2, Masaaki Noji1, Akemi Umeyama1 (1. Pharm.Sci.,Tokushimabunri Univ., 2. Medical Mycology Research Center, Chiba Univ.)
[28Q-pm156]Decomposition of Ginsenosides on TLC Plate
○Kazuhiro Hirakura1, Toshihiro Kammoto1, Kaori Yomura1, Yasushi Igarashi1, Tadashi Matsuura1 (1. Tsumura & Co.)
[28Q-pm157S]Substances for maintaining water quality eluted from pothos (Epipremnum aureum)
○Risa Shimizu1, Akira Uenoyama1, Fumika Kitagawa1, Kyoko Ishiguro1, Hisae Oku1 (1. Mukogawa Woman's Univ.)