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Enzyme-transition-metal hybrid catalysis: Chiral-switching Factory

Synthetic organic chemistry can design, supply, and improve organic molecules, and thus is a foundation of the academic and technological aspects of all modalities in drug discovery. Catalysis and natural product synthesis are two apexes of basic science, where Japan can still lead the world. This symposium was planned in order to widely share the latest research results in the field of synthetic organic chemistry, which is a strong powerplant of drug discovery. In recent years, the concept of hybrid catalysis has been born. Hybrid catalysis enables to develop extremely efficient organic synthesis, which was impossible in the past, by combining plural catalysts having independent functions. Hybrid catalysis makes it possible to select synthetic routes that fundamentally transform and evolve conventional retrosynthesis. At this symposium, researchers who are at the forefront of catalysis and natural product synthesis will be brought together to present and discuss the latest results, centering on the concept of hybrid catalysis. We hope that this will be a great opportunity to share new trends in synthetic organic chemistry, which is the basis of drug discovery and pharmaceutical sciences, with many researchers in broad fields, including students.

Hybrid catalysis

The 141st Annual Meeting of the Pharmaceutical Society of Japan (Hiroshima)

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[S08-5]Enzyme-transition-metal hybrid catalysis: Chiral-switching Factory

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