The 141st Annual Meeting of the Pharmaceutical Society of Japan (Hiroshima)
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Session Details

Poster Presentation(A) Organic Chemistry

[27P01]ケミカルバイオロジー

Sat. Mar 27, 2021 9:00 AM - 6:00 PM JST
Sat. Mar 27, 2021 12:00 AM - 9:00 AM UTC
[Room P01] Poster Presentation Online

[27P01-054S]Development of novel IL-6R/IL-6 interaction inhibitors for severe COVID-19 pneumonia treatment

○Yukio Takamori1, Takehiro Ando1, Daisuke Fuji2, Mizuki Yamamoto1, Takashi Kawakami3,4 (1. Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ., 2. Fac. Life Environ. Sci., Yamanashi Univ., 3. Grad. Fac. Interdiscip. Res, Yamanashi Univ., 4. JST PRESTO)

[27P01-055S]Development of novel TNF-alpha/TNFR interaction inhibitors for autoimmune disease treatment

○Keita Tsukamoto1, Takehiro Ando1, Daisuke Fuji2, Mizuki Yamamoto1, Takashi Kawakami3,4 (1. Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ., 2. Fac. Life Environ. Sci., Yamanashi Univ., 3. Grad. Fac. Interdiscip. Res., Yamanashi Univ., 4. JST, PRESTO)

[27P01-056S]Development of novel STING ligands for immune regulation

○Yuta Yanase1,2, Kentaro Ikeda1,2, Genichiro Tsuji2, Norihito Shibata2, Mikihiko Naito3, Yosuke Demizu1,2 (1. Grad. Sch. Med. life Sci., Yokohama city Univ., 2. NIHS, 3. Grad. Sch. Pharm. Sci., The Univ. of Tokyo)

[27P01-058S]Development of novel PCSK9/LDLR interaction inhibitors for the development of therapeutic agents for hypercholesterolemia

○Takumi Yokoyama1, Takehiro Ando1, Daisuke Fuji2, Mizuki Yamamoto1, Takashi Kawakami3,4 (1. Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ., 2. Fac. Life Environ. Sci., Yamanashi Univ., 3. Grad. Fac. Interdiscip. Res, Yamanashi Univ., 4. JST, PRESTO)

[27P01-059S]Development of novel VEGFR2/VEGF interaction inhibitors for the development of angiogenesis inhibitors

○Daisuke Horiuchi1, Takehiro Ando1, Daisuke Fuji2, Mizuki Yamamoto1, Takashi Kawakami3,4 (1. Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ., 2. Fac. Life Environ. Sci., Yamanashi Univ., 3. Grad. Fac. Interdiscip. Res., Yamanashi Univ., 4. JST, PRESTO)

[27P01-060S]Development of novel HER3/HRG interaction inhibitors for cancer treatment

○Takehiro Ando Ando1, Rina Iwamoto1, Daisuke Fuji2, Mizuki Yamamoto1, Takashi Kawakami3,4 (1. Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ., 2. Fac. Life Environ. Sci., Yamanashi Univ., 3. Grad. Fac. Interdiscip. Res., Yamanashi Univ., 4. JST, PRESTO)

[27P01-061S]Development of novel PD-L1/PD-1 interaction inhibitors for cancer immunotherapy

○Rina Iwamoto1, Takehiro Ando1, Daisuke Fuji2, Mizuki Yamamoto1, Takashi Kawakami3,4 (1. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ., 2. Fac. Life Environ. Sci., Yamanashi Univ., 3. Grad. Fac. Interdiscip. Res., Yamanashi Univ., 4. JST, PRESTO)

[27P01-062S]Development of novel photo-responsive oligonucleotides targeting genes having a point mutation

○Ryo Tahara1, Yui Sakai1, Tsuyoshi Yamamoto2, Chikara Dohno3, Takehiko Wada4, Asako Yamayoshi2,5 (1. Sch. Pharm. Sci., Nagasaki Univ., 2. Grad. Sch. Biomed. Sci., Nagasaki Univ., 3. Inst. of Sci. Indust. Res., Osaka Univ., 4. Inst. of Multi-discip. Res. for Adv. Mater., Tohoku Univ., 5. PRESTO･JST)

[27P01-063S]Photo-cross-linking behaviors of psoralen-conjugated triplex forming oligonucleotides targeting double-stranded DNAs

○juki nakao1, Honoka Eshima2, Tsuyoshi yamamoto1, Chikara Dohno3, Takehiko Wada4, Asako Yamayosi1,5 (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Sch. Pharm. Sci., Nagasaki Univ., 3. Inst. of Sci. Indust.Res., Osaka Univ., 4. Inst. of Multi-discip. Res. for Adv. Mater., Tohoku Univ., 5. PRESTO･JST)

[27P01-064]Strand-invasion of duplex DNA by peptide nucleic acid oligomers containing cationic guanine analogues

○Shun-suke Moriya1, Keiko Kuwata2, Yasutada Imamura3, Yosuke Demizu4, Masaaki Kurihara5, Atsushi Kittaka1, Toru Sugiyama1 (1. Fac. of Pharma-Sciences, Teikyo Univ., 2. WPI-ITbM, Nagoya Univ., 3. Sch. of Adv. Eng., Kogakuin Univ., 4. Div. of Org. Chem., Nat. Inst. of Health Sci., 5. Dept. of Pharm. Sci., Int. Univ. of Health and Welfare)

[27P01-065]A new strategy for siRNA stabilisation by using an artificial cationic oligosaccharide combined with phosphorothioate linkages

○Atsushi Irie1, Kazuki Sato2, Rintaro Hara2,3, Takeshi Wada2, Futoshi Shibasaki1 (1. Tokyo Metro. Inst. Med. Sci., 2. Tokyo Univ. Sci., 3. Tokyo Med. Dent. Univ.)

[27P01-066]Development of proteolysis-inducing chimeric molecules using peptide-based ligands

○Nobumichi Ohoka1, Hidetomo Yokoo2, Takao Inoue1, Yosuke Demizu2 (1. Div. Mol. Tar. & Gene Thera. Pro., NIHS, 2. Div. Org. Chem., NIHS)

[27P01-067S]Development of novel tyrosine selective modification reagents

○Shogo Miyano1, Shusuke Tomoshige1, Minoru Ishikawa1, Shinichi Sato1,2 (1. Grad. Sch. Life Sci., Tohoku Univ., 2. FRIS, Tohoku Univ.)

[27P01-068S]Development of photoremovable protective group activatable by reactive oxygen species

○Daiki Kato1, Tomoya Hirano2, Hiroyuki Kagechika1 (1. Inst.Biomat.Bioeng., Tokyo Med.Dent.Univ., 2. Osaka University of Pharmaceutical Sciences)

[27P01-069]Development of detection method for isomerized Asp residue in proteins using novel chemical tag

○Shota Morimoto1, ami yamaguchi1, hiromasa tsuruta1, yutaka sadakane1 (1. suzuka university of medical science)

[27P01-070]Development of Boron-Sensor for the Analysis of Boron-Pharmaceuticals

○Yoshihide Hattori1, Miki Ishimura1, Youichirou Ohta1, Hiroshi Takenaka1, Mitsunori Kirihata1 (1. Research Center of BNCT, Osaka Pref. Univ. )

[27P01-071]Development of Selective Kinase Inhibitor Tools (SKIT) Library

○Terufumi Takagi1, Michiko Tawada1, Yoshi Nara1, Ikuo Miyahisa1, Atsuko Ochida1, Takeshi Yamamoto1, Tadashi Hidaka1, Yoshihiko Hirozane1 (1. Takeda Pharmaceutical Company Limited)
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