Session Details
[29P01]医薬品設計/合成医薬品
Mon. Mar 29, 2021 9:00 AM - 6:00 PM JST
Mon. Mar 29, 2021 12:00 AM - 9:00 AM UTC
Mon. Mar 29, 2021 12:00 AM - 9:00 AM UTC
[Room P01] Poster Presentation Online
[29P01-054S]Development of LXR-degradation inducers
○Hanqiao Xu1,2, Genichiro Tsuji1, Nobumichi Ohoka1, Mikihiko Naito3, Yosuke Demizu1,4 (1. National Institute of Health Sciences, 2. College of Bioresource Sciences, Nihon University, 3. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 4. Graduate School of Medical Life Sciences, Yokohama City University)
[29P01-055S]Development of aptamer-based estrogen receptor alpha degraders
○Haruna Tsujimura1,2, Miyako Naganuma2,3, Nobumichi Ohoka2, Yoshitomo Suhara1, Kenji Matsuno3, Mikihiko Naito4, Takao Inoue2, Genichiro Tsuji2, Yosuke Demizu2,5 (1. Shibaura Institute of Technology, 2. National Institute of Health Sciences, 3. Graduate School of Engineering, Kogakuin University, 4. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 5. Graduate School of Medical Life Science, Yokohama City University)
[29P01-056S]Development of Photoswitchable Estrogen Receptor Ligands
○Keisuke Tsuchiya1,2, Tomohiro Umeno3, Genichiro Tsuji2, Hidetomo Yokoo2,4, Kiyoshi Fukuhara1, Takashi Misawa2, Yosuke Demizu2,4 (1. Grad. Sch. Pharm., Showa Univ., 2. NIHS, 3. Grad. Sch. Showa Pharm. Univ., 4. Grad. Sch. Med. Life Sci., Yokohama city Univ.)
[29P01-057]Biological Evaluation of Symmetric and Non-symmetric Boronic Acid Derivatives
○Kaori Ota1, Jian-Rong Zhou2, Kazumi Yokomizo2, Nobuhiro Kashige1, Makoto Furutachi1 (1. Fukuoka University, 2. Sojo University)
[29P01-058]Synthesis of C3 Symmetric Triazine Derivatives.
○Shunsuke Shimomura1, Jian-Rong Zhou2, Kazumi Yokomizo2, Makoto Furutachi1, Nobuko Mibu1, Kunihiro Sumoto1 (1. Fukuoka University, 2. Sojo University)
[29P01-059]Design and synthesis of quinolinone derivatives which inhibit influenza virus RNA polymerase
○Satoshi Mizuta Mizuta1, Hiroki Otaki1, Ken Watanabe2 (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Yasuda Women’s Univ.)
[29P01-060]Relationship of GAA mutation sites and pharmacological chaperone effects by 1-deoxynojirimycin
○Atsushi Kato1, Shuki Imaeda1, Mizuki Hata1, Izumi Nakagome2, Shuichi Hirono2, Nobutada Tanaka2 (1. Department of Hospital Pharmacy, University of Toyama, 2. School of Pharmaceutical Sciences, Kitasato University)
[29P01-061]In silico screening of novel allosteric activators for β-glucocerebrosidase with the aim of developing a therapeutic drug for Gaucher's disease
○Izumi Nakagome1, Atsushi Kato2, Kaho Hirose1, Yuna Shimadate2, Mizuki Hata2, Noriyuki Yamaotsu1, Nobutada Tanaka1, Shuichi Hirono1 (1. Sch. Pharm., Kitasato Univ., 2. Department of Hospital Pharmacy, University of Toyama)
[29P01-062]Design, synthesis and glycosidase inhibition of broussonetines and their analogues
○Yuna Shimadate1, Kosuke Yoshimura1, Atsushi Kato1 (1. Department of hospital pharmacy, University of Toyama)
[29P01-063]Structure-based drug design of natural ligand-nonmimetic inhibitors for lipid-transfer protein CERT
○Naoki Nakao1, Masaharu Ueno2, Shota Sakai3, Daichi Egawa3, Hiroyuki Hanzawa1, Shohei Kawasaki1, Keigo Kumagai3, Makoto Suzuki1, Shu Kobayashi4, Kentaro Hanada3 (1. Daiichi Sankyo RD Novare Co., Ltd., 2. Department of Natural Science, Graduate School of Advanced Technology and Science, Tokushima University, 3. National Institute of Infectious Diseases, 4. Department of Chemistry, School of Science, the University of Tokyo)
[29P01-064S]Synthesis of oligonucleotides introduced with bearing imidazole modified pyrrolepolyamide and evaluation of RNA cleavage activity.
○Ibuki Hirota1, Taira Matsubara1, Koichiro Ota1, Hiroaki Miyaoka1, Kazuo Kamaike1 (1. Tokyo University of Pharmacy and Life Sciences)
[29P01-065S]Nobel synthetic studies of Pemetrexed prodrugs aiming for oral administration
○Kasumi Miyoshi1, Noboru Hayama1, Kiyofumi Inamoto1, Anna Miyazaki1, Akira Nakamura2, Tomohiro Maegawa2, Toru Otori2, Kenji Matsuyama3, Tetsutaro Kimachi1 (1. Sch. Pharmacy and Pharmaceutical Sci., Momen's Univ., 2. Fac. Pharmacy and Pharmaceutical Sci., Kindai Univ., 3. Hanshin dispensing pharmacy)
[29P01-066S]Design and synthesis of novel ADCs with STLC derivatives
○Taiki Ichida1, Ryota Fukai1, Hisashi Murakami1, Nao Miyoshi1, Naohisa Ogo1, Akira Asai1 (1. Grad. Div. Pharm. Sci., Univ. of Shizuoka)
[29P01-067S]Synthesis and anti HIV-1 activity evaluation of Alkenyldiarylmethanes as non-nucleoside HIV-1 reverse transcriptase inhibitor incorporating hydoxymethyl group
○Takanori Takei1, Xuan Meiyan1, Jun Takayama1, Takeshi Sakamoto1 (1. Fac. Pharm. Sci., Josai Univ.)
[29P01-068S]Synthesis of a novel boron compounds added nuclear translocation abilities by a peptides
○Tomonori Sakai1, Chiemi Nakano1, Hitoshi Hori3, Aya Okuda2, Masaaki Sugiyama2, Akira Shigenaga1, Yuhki Sato1, Makoto Shirakawa1,4 (1. Fukuyama Univ., 2. Kyoto Univ., 3. Niigata Univ., 4. Tsukuba Univ.)
[29P01-069S]CCR2 binding inhibitory activity of N, N'-diallyl urea derivatives having a nitrogen-containing aromatic heterocycle
Ryo Murashige1, ○Mayu Noguchi1, Nanaka Izumi1, Misaki Uno1, Kouki Fukushima1, Kayoko Yamasaki1, Takanori Nakamura1 (1. Dep. Pharm. Sci., Himeji-Dokkyo Univ.)
[29P01-070]Synthesis and evaluation of poly-hydric phenol derivatives of diphenylbenzofuran as amyloid β fibril formation inhibitor / fibril dissociator.
Aya Ogasawara1, Kota Nakajima1, Taimei Nakayama1, Yurika Ikegami1, Yuuki Saito1, Manabu Shimazaki1, ○Hideharu Suzuki1 (1. Faculty of Pharmaceutical Sciences, Teikyo Heisei University)