The 142nd Annual Meeting of the Pharmaceutical Society of Japan (Nagoya)
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Session Details

Poster Presentation(C) Pharmaceutical Biology

[26PO2-am2]Drug metabolism

Sat. Mar 26, 2022 10:50 AM - 12:30 PM JST
Sat. Mar 26, 2022 1:50 AM - 3:30 AM UTC
[Room PO2] Lounge next to Room K Bldg. 2: 2F
【説明時間】11:05～12:15
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-01]Role of interleukin-6 in down-regulation of cytochrome P450 in sepsis model mice

○Takashi Ashino1, Yuki Nakamura1, Hirokazu Ohtaki2, Yoichiro Iwakura3, Satoshi Numazawa1 (1. Sch. Pharm., Showa Univ., 2. Sch. Med., Showa Univ., 3. Res. Inst. Biomed. Sci., Tokyo Univ. Sci.)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-02]Anti-inflammation and induction of drug-metabolizing enzymes by falcarindiol and its metabolites

○Tomokazu Ohnuma1, Yuika Takeda1, Takahito Nishiyama1, Kenichiro Ogura1, Akira Hiratsuka1 (1. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-03]Functional analysis of the ATP-sulfurylase region of PAPS synthase

○Takahito Nishiyama1, Yasuhiro Kawamori1, Momoka Tadokoro1, Tomomi Kitagawa1, Tomokazu Ohunma1, Kenichiro Ogura1, Satoshi Yamaori1 (1. Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-04]Dimer formation ability of 5-fluorouracil metabolizing enzyme dihydropyrimidine dehydrogenase variant

○Kenichiro Ogura1, Teruyuki Ishikawa1, Saori Kato1, Yuika Sanada1, Tomokazu Ohnuma1, Takahito Nishiyama1, Satoshi Yamaori1 (1. Sch. Pharm., Tokyo Univ. Pharm. Life Sci.)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-05S]Effects of AKR1C3 genetic polymorphism on reductase activities for various drugs

○Shiori Takano1, Tatsuki Fukami1,2, Hiroyuki Ichida1, Kohei Suzuki1, Masataka Nakano1,2, Miki Nakajima1,2 (1. Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Pharmacy, Kanazawa Univ., 2. Nano Life Science Institute)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-06S]Evaluation of the mechanism of fatty liver development focusing on the differential expression of aldehyde oxidase among mouse strains

○Katsunobu Utsumi1, Seigo Sanoh1,2, Naoki Takaoka1,2, Kazumi Sugihara3, Yaichiro Kotake1 (1. Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 2. Sch. Pharm. Sci, Wakayama Med. Univ., 3. Hiroshima International Univ.)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-07]Effects of chronic administration of 25-hydroxyvitamin D3 on CYP24A1-knockout rats

○Risa Okon1, Mana Yamaguchi1, Miyu Nishikawa1, Shinichi Ikushiro1, Toshiyuki Sakaki1, Kaori Yasuda1 (1. Grad. Sch. Eng., Toyama Pref. Univ.)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-08]Prediction of input parameters for simplified physiologically based pharmacokinetic models and oral absorption of various chemicals/drugs in humans

Yusuke Kamiya1, Tasuku Sato 1, Saho Morikuni 1, Masayoshi Utsumi1, Tomonori Miura 1, Norie Murayama 1, Makiko Shimizu 1, Kentaro Handa 2, Masato Kitajima2, Fumiaki Shono3, ○Hiroshi Yamazaki1 (1. Showa Pharma Univ, 2. Fujitsu, 3. Nara Institute of Sci Tech)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-09]Dog cytochrome P450 3A enzymes expressed in liver and intestine

○Norie Murayama1, Yutaro Noda1, Shiori Jikuya2, Yasuhiro Uno2, Hiroshi Yamazaki 1 (1. Showa Pharma. Univ., 2. Kagoshima Univ., Vet Med.)
10:50 AM - 12:30 PM JST(1:50 AM - 3:30 AM UTC)

[26PO2-am2-10]Flavin-containing monooxygenase 3 variants from database in Tohoku Medical Megabank Organization

○Makiko Shimizu1, Miaki Makiguchi1, Yuria Nakamura1, Eiji Hishinuma2,3, Sakae Saito2,3, Masahiro Hiratsuka2,3,4, Hiroshi Yamazaki1 (1. Showa Pharma Univ, 2. INGEM, Tohoku Univ, 3. ToMMo, Tohoku Univ, 4. Grad Sch Pharm Sci, Tohoku Univ)
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