General information

Announcements(0)

Greetings from the Chair

Overview

Web abstract

Registration

Information for Speakers, Presenters and Chairs

Program

Sessions

Search presentations

General information 2

Abstract Submission (Oral/Poster Presentation)

pharm143_en.png

icon_20251203182619268.png

Change account information such as the email address and password on the account setting screen common to Confit.

Login required to view

Password required to view

Presentation Information

Session Details

<br>Enter the password to view the abstracts.<br>The password will be emailed to those who have completed the registration.

To browse or post comments, you must log in.

You cannot post comments as it is outside the comment posting period.

This comment has been deleted. You cannot reply to this comment.

Program Type

Announcements

Profile management

Bookmark

Download PDF for print

Timetable

Development and structural analysis of membrane-permeable cyclic peptides by cyclopropane-based conformational restriction strategy

Recently, drug discovery research on new modalities using macromolecules, and small and medium molecules has been actively conducted with the aim of creating innovative drugs. Among them, antibody drugs with target specificity and weaker side effects, nucleic acid drugs targeting DNA and RNA, and peptide drugs inhibiting protein-protein interactions, have many advantages over conventional small molecule drugs. However, the large molecular size and high polarity of these molecules make it difficult for them to penetrate into cell. In addition, they lack chemical stability in vivo and are easily degraded. Therefore, it is very important to develop techniques to deliver antibodies, nucleic acids, and peptides into cells and to modify molecules to improve their chemical stability.<br />This symposium will focus on antibodies, nucleic acids, and peptides as new modalities, and will introduce the research of graduate students who are energetically engaged in drug discovery research. We hope that this symposium will provide an opportunity for active discussions and lead to the creation of the next generation of drugs.

Drug Discovery Research Pioneered by Young Researchers~Toward the Creation of Innovative Drugs~

The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)

Presentation Information

[GS02-04]Development and structural analysis of membrane-permeable cyclic peptides by cyclopropane-based conformational restriction strategy

Password required to view