The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)
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Session Details

Poster Presentation(B) Pharmaceutical Physics

[26P1-pm1]Structural chemistry, spectroscopy/Structure, physical property, and reactivity of biological materials/Biopolymers/Others

Sun. Mar 26, 2023 2:00 PM - 3:40 PM JST
Sun. Mar 26, 2023 5:00 AM - 6:40 AM UTC
[Room P1] Gymnasium 1F

[26P1-pm1-042]Development of aggregation-induced organic fluorescent molecules with high luminous properties

○Masayori Hagimori1, Fumiko Hara1, Tatsusada Yoshida2, Yukiko Ogawa2, Keitaro Tanaka3 (1. Sch. Pharm., Mukogawa Women’s Univ., 2. Fac. Pharm. Sci., Nagasaki Int. Univ., 3. Shimonoseki Med. Ctr)

[26P1-pm1-043]Synthesis and characterization of helical pyrylium salts

○Kazuteru Usui1, Ryosuke Eto1, Riku Arino1, Shota Matsumoto1, Tomohiro Umeno1, Satoru Karasawa1 (1. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-044S]Synthesis and characterization of dihydroaza[5]helicenes

○Kazuho Ishii1, Satsuki Murase1, Tomohiro Umeno1, Kazuteru Usui1, Satoru Karasawa1 (1. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-045S]Aqueous Self-assembly Behavior and Physical Properties of NO Radicals with Five-membered Ring

○Yuika Akizuki1, Naoko Iizuka1, Tomohiro Umeno1, Kazuteru Usui1, Satoru Karasawa1 (1. Faculty of Pharm.Sci., Showa Pharm.Univ.)

[26P1-pm1-046]Preparations, X-ray structures, and physical properties of NO radicals bearing polar substituents

○Naoko iizuka1, Ryoma Shiraishi2, Tomohiro Umeno1, Kazuteru Usui1, Satoru Karasawa1 (1. Grad. Sch. Pharm. Sci., Showa Pharmacetuical Univ., 2. Grad. Sch. Pharm. Sci., Kyushu Univ.)

[26P1-pm1-047]Non-preparative structure analysis of trace organic impurities in a pharmaceutical material by DNP-NMR technique

○Tomohiko Ueda1, Yoshiaki Takai1, Ayaka Maeno2, Katsuaki Suzuki2, Hironori Kaji2 (1. Sumitomo Pharma Analytical Research & Development Laboratories, 2. Institute for Chemical Research, Kyoto University)

[26P1-pm1-048]The role of structural dynamics in ligand binding of the nuclear receptor PPARγ

○Kohei Tainaka1, Takuya Yoshida1, Rina Iwamoto1, Tomohito Hanaoka1, Kazuki Kawahara1, Tadayasu Ohkubo1 (1. Grad. Sch of Pharm. Osaka Univ.)

[26P1-pm1-049]Study on the development of a reversible fluorescence labeling reagent for amines based on the formation of enamines

○Tomohiro Umeno1, Tomoki Kawahara1, Kazuteru Usui1, Satoru Karasawa1 (1. Showa Pharmaceutical University)

[26P1-pm1-050S]Application of amine detection reagents toward solid-phase peptide synthesis using chromophore with HCl salt

○Moeka Fujihara1, Tomohiro Umeno1, Kazuteru Usui1, Satoru Karasawa1 (1. Faculty of Pharm.Sci., Showa Pharm. Univ.)

[26P1-pm1-051S]Development halogenated naphthyridine as fluorescent labeling reagents with intense emission in aqueous environment

○Lisa Muroi1, Tomohiro Umeno1, Kazuteru Usui1, Satoru Karasawa1 (1. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-052S]Self-Assembly Behavior and Characterization of Emissive Imidazonaphthyridine Derivatives

○Shota Matsumoto1, Tomohiro Umeno2, Kazuteru Usui2, Koichi Hamada2, Akihiro Mizutani2, Satoru Karasawa2 (1. Grad. Sch. Pharm. Sci., Showa Pharm. Univ., 2. Faculty of Pharm. Sci., Showa Pharm. Univ.)

[26P1-pm1-053S]Aqueous Self-assembly Behavior for Hexaazapentacene Derivatives with Intense Emission

○Kanae Baba1, Tokimi Oyama1, Taro Saito1, Tomohiro Umeno1, Yasufumi Fuchi2, Kazuteru Usui1, Satoru Karasawa1 (1. Faculty of pharm.Sci.,Showa pharm. Univ., 2. Faculty of pharm.Sci.,Tokushima Bunri pharm.)

[26P1-pm1-054S]Investigation of electrochemical measurement system to search for redox control substances of water-insoluble quinone

○Sawa Hayashi1, Riko Miyaki1, Kaoru Terao1, Nao Okamoto1, Noriko Okumura1 (1. Kinjo Gakuin University )

[26P1-pm1-055S]Electrochemical approach for predicting the cytotoxicity of polyphenols

○Riko Miyaki1, Utano Ohno1, Sawa Hayashi1, Yuki Ichinose1, Kaori Suzuki1, Noriko Okumura1 (1. Kinjo Gakuin University)

[26P1-pm1-056S]Complex Formation of Rosmarinic acid and Berberin in Aqueous Solution

○Yoshiyuki Akita1, Hiroyuki Tsutsumi1, Rie Nakashima1, Tomonori Ohata1, Hirohito Ikeda1 (1. Fac.Pharm.Sci., Fukuoka Univ.)

[26P1-pm1-057S]Development of Separation Method for (-)-Epigallocatechin-3-O-gallate and (-)-Epigallocatechin Using Cucurbit[7]uril

○An Miura1, Hiroyuki Tsutsumi1, Rie Nakashima1, Tomonori Ohata1, Hirohito Ikeda1 (1. Fac. Pharm. Sci., Fukuoka Univ.)

[26P1-pm1-058S]Study on Formation of Inclusion Complex between Anti-herpesvirus Drugs and Cucurbit[7]uril

○Ryota Tsukiashi1, Rie Nakashima1, Hiroyuki Tsutsumi1, Tomonori Ohata1, Hirohito Ikeda1 (1. Fac. Pharm.Sci., Fukuoka Univ.)

[26P1-pm1-059S]Improving water solubility of azithromycin using cyclodextrins and sugars

○Kana Yamada1, Tomonori Ohata1, Rie Nakashima1, Hiroyuki Tsutsumi1, Hirohito Ikeda1 (1. Fac.Pharm.Sci.,Fukuoka Univ)

[26P1-pm1-060S]Comparison of Content of Dissolution and Crystallization Forms of Active Ingredients in Steroid Ointments : Triamcinolone Acetonide Ointment

○Yuta Kawabe1, Tomonori Ohata1, Rie Nakashima1, Hiroyuki Tsutsumi1, Hirohito Ikeda1 (1. Fac. Pharm. Sci., Fukuoka Univ.)

[26P1-pm1-061]Analysis of the secondary structure of Rab12, a protein implicated in the pathogenesis of Parkinson’s disease, and its phosphorylation by LRRK2

○GENTA ITO1, Ryo Nakamura1, Naoko Utsunomiya-Tate1 (1. Faculty of Pharma-Science, Teikyo Univ.)

[26P1-pm1-062S]Effects of amyloid beta-peptides on the serotonin-mediated copper reduction

○Takumi Kurihara1, Risa Aoyagi1, Saki Anata1, Takashi Miura1 (1. Dep. Pharm. Sci. Int. Univ. Health & Welfare)

[26P1-pm1-063]Structural change and aggregation by asparagine deamidation in γS-crystallin

○koichi kato1,2,3, tomoki nakayoshi2,4, Eiji Kurimoto2, akifumi oda2,5, yoshinobu ishikawa1 (1. Pharm. Sci., Shonan Univ. of Med. Sci, 2. Facul. of Pharm., Meijo Univ., 3. Coll. of pharm., Kinjo Gakuin Univ., 4. Grad. Inf. Sci., Hiroshima City Univ., 5. Inst. Prot. Res., Osaka Univ.)

[26P1-pm1-064]Influences of chemical modifications on the structural properties and amyloid fibril formation of human serum amyloid A

○Masafumi TANAKA1, Toru Takarada1, Toshiyuki Yamada2, Satomi Nadanaka1, Hiroshi Kitagawa1 (1. Kobe Pharm. Univ., 2. Jichi Med. Univ.)

[26P1-pm1-065]A possible role for N-glycosylation in the cellular secretion and interacting protein of serum amyloid A4

○Toru Takarada1, Rikako Fujinaka1, Toshiyuki Yamada2, Masafumi Tanaka1 (1. Kobe Pharm. Univ., 2. Jichi Med. Univ.)

[26P1-pm1-066S]Kinetic Approach to the Mechanism of Zinc Finger Oxidation by Hydrogen Peroxide

○Yuri Kawahito1, Kanae Kishi2, Mayu Yokozeki1, Yuka Nakagawa3, Mami Hamori4, Shigeru Negi1 (1. Faculty of Pharm. Sci., DWCLA Univ., 2. Grad. Sch. Med., Hiroshima Univ., 3. Grad. Sch. Sci., Hyogo Univ., 4. Faculty of Pharm., Kitasato Univ.)

[26P1-pm1-067S]Identification and characterization of middle molecular weight compound inhibitors of Fcγ receptors

○Xu Pan1, Tetsushi Hayakawa1, Izumi Kato1, Manabu Nagao1, Takashi Tadokoro1, Katsumi Maenaka1 (1. Pharm. Sci., Hokkaido Univ.)

[26P1-pm1-068]Redox-independent conformational fluctuation near the active site of Escherichia coli DsbA studied by high-pressure NMR

○Ryo Kitahara1,2, Junya Yamamoto2, Soichiro Kitazawa1, Yohei Miyanoiri3, Biswaranjan Mohanty4, Martin Scanlon5 (1. Col. Pharm. Sci., Ritsumeikan Univ., 2. Grad. Sch. Pharm. Sci. Ritsumeikan Univ., 3. IPR, Osaka Univ., 4. Univ. of Sydney, 5. Monash Univ.)

[26P1-pm1-069S]Novel ring formation by mutated human 20S proteasome alpha subunits

○Fuka Ikami1, Shiori Kakiya1, Keiichiro Imai1, Yousuke Ryu1, Akifumi Oda1,2, Eiji Kurimoto1 (1. Fac. Pharm. Meijo Univ., 2. Inst. Protein Res. Osaka Univ.)

[26P1-pm1-070S]Investigation of the importance of the number of amino acids between Cys residues in redox couples in vivo using zinc finger protein as a model.

○Mayu Yokozeki1, Yuri Kawahito1, Kanae Kishi2, Yuka Nakagawa3, Mami Hamori4, Shigeru Negi1 (1. Faculty of Pharm. Sci., DWCLA Univ., 2. Grad. Sch. Med., Hiroshima Univ., 3. Grad. Sch. Sci., Hyogo Univ., 4. Faculty of Pharm., Kitasato Univ.)

[26P1-pm1-071]Functional analysis of activation domain of transcription factor Sp1

○Jun Kuwahara1, Yuina Tsumori1, Shunsuke Tajima1, Masaru Hoshino2, Katsumi Matsuzaki2 (1. Fac. Pharm. Sci., Doshisha Women's Univ., 2. Grad. Sch. Pharm. Sci., Kyoto Univ.)

[26P1-pm1-072S]Physical property and amyloid-promoting effect of protein amyloid cofactor ApoA-IV

○Yoshito Naito1, Norihiro Namba1, Takashi Ohgida1, Hiroyuki Saito1 (1. Kyoto Pharm. Univ.)

[26P1-pm1-073S]Effect of amyloidogenic mutation on the structural stability and fibril-forming property of apoA-I

○Norihiro Namba1, Miu Ueno1, Hiroko Asahina1, Takashi Ohgita1, Toshinori Shimanouchi2, Takeshi Sato1, Hiroyuki Saito1 (1. Kyoto Pharm. Univ., 2. Okayama Univ.)

[26P1-pm1-074S]Physicochemical evaluation of the reaction propensity of novel anti-apoE monoclonal antibody against apoE isoforms

○Koto Sakai1, Nodoka Fukui1, Norihiro Namba1, Takashi Ohgita1, Yuki Kiguchi2, Izumi Morita2, Hiroyuki Oyama2, Kohjiro Nagao1, Norihiro Kobayashi2, Hiroyuki Saito1 (1. Kyoto Pharm. Univ., 2. Kobe Pharm. Univ.)

[26P1-pm1-075]The analysis of the relationship between D-isomerization of amino acids in the tau microtubule-binding repeat and the fibrillation/aggregation

○Takuya Murata1, Haruna Otsuka1, Mana Yahagi1, Rina Kokusyo1, Genta Ito1, Naoko Tate1 (1. Fac. Pharm. Sci., Teikyo Univ.)

[26P1-pm1-076S]Quantitative evaluation of DNA repair mechanism involving PARP-1 using the QCM method

○Sakura Hosoi1, Midori Tsuruta1, Masato Mashimo1, Hiroyuki Hurusawa2, Shigeru Negi1 (1. Faculty of Pharm. Sci., DWCLA Univ., 2. Grad. Sch., Yamagata Univ)
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