The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)
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Session Details

Poster Presentation(A) Pharmaceutical Chemistry

[26P1-am1]Chemical biology 1/Screening

Sun. Mar 26, 2023 10:00 AM - 11:40 AM JST
Sun. Mar 26, 2023 1:00 AM - 2:40 AM UTC
[Room P1] Gymnasium 1F

[26P1-am1-051S]Search for useful substances by co-culture of lactic-acid bacteria and animal cells and analysis of their production mechanisms

○Rio Hosouchi1, Shun Saito1, Midori A. Arai1 (1. Fac. Sci. Tech., Keio Univ.)

[26P1-am1-052]Hyphae formation inhibitor against Candida albicans from Albatrellus spp. (2)

○Ayumu Hirabayashi1, Sanae Kurakado1, Hiroaki Sasaki1, Takashi Sugita1, Kiyotaka Koyama1, Kaoru Kinoshita1 (1. Meiji Pharm Univ.)

[26P1-am1-053S]Anti-hyperlipidemic Effects of Momordin Ic from the Fruit of Kochia scoparia

○Ryuya Takada1, Akifumi Nagatomo1, Mayu Morimoto1, Yoshiaki Manse1, Jianbo Wu2, Kenchi Miyasaka2, Hiroshi Simoda2, Hisashi Matsuda1, Toshio Morikawa1 (1. Pharm. Res. Tech. Inst. Kindai Univ., 2. Oryza Oil Fat Chem. Co. Ltd.)

[26P1-am1-054]Inhibitory effect of mountain caviar fruit extract and the saponins on postprandial blood sugar

○Hiroshi Shimoda1, Kenchi Miyasaka1, Ryuya Takada2, Wakana Yamada1, Marina Hirano1, Yoshiaki Manse2, Toshio Morikawa2, Jianbo Wu1 (1. Oryza Oil&Fat Chemical Co.,Ltd., 2. Pharmaceutical Research and Technology Institute, Kindai University)

[26P1-am1-055S]Co-culture of pathogenic fungi Aspergillus terreus and immune cells
for activating silent genes

○Yukiko Ujie1, Shun Saito1, Takashi Yaguchi2, Midori A. Arai1 (1. Fac. Sci. Tech., Keio Univ., 2. Med. Myc. Res. Cent., Chiba Univ.)

[26P1-am1-056S]Search for Anti-cancer Drug Seeds from Microorganisms targeting Notch-inactive Cancer

○Shiina Suzuki1, Shun Saito1, Yoshinori Makita1,2, Kazuo Shin-ya3, Midori A. Arai1 (1. Fac. Sci. Tech., Keio Univ., 2. Grad. Sch. Pharm. Sci., Chiba Univ., 3. AIST)

[26P1-am1-057S]Evaluation of inhibitory activity against cancer stem cells
by heat shock metabolites, maniwamycins
produced by thermotolerant Streptomyces sp. JA74

○Nanoha Izawa1, Shun Saito1, Kayo Funayama1, Wataru Kato1, Midori A Arai1 (1. Fac. Sci. Tech., Keio Univ.)

[26P1-am1-058S]Elucidation of the mechanism of spirooxindole, an activator of neural stem cell differentiation

○Haruki Oba1, Haruka Kawano2, Miyu Okano2, Takayoshi Arai3, Masami Ishibashi2, Midori A. Arai1 (1. Fac. Sci. Tec., Keio Univ., 2. Grad. Sch. Pharm. Sci., Chiba Univ., 3. Grad. Sch. Sci., Chiba Univ.)

[26P1-am1-059S]The anti-inflammatory activity and its mechanism of action of ent-kaurane type diterpenoid enmein isolated from Isodonis Herba

○Sakura Yamanada1, Yoshiaki Manse1, Kota Sumida1, Yusuke Sakamoto1, Toshio Morikawa1,2 (1. harmaceutical Research and Technology Institute, Kindai University, 2. Antiaging Center, Kindai University)

[26P1-am1-060S]Search for anti-cancer agents from marine resources.

○Teruki Tanaka1, Kenichiro Nagai2, Takeshi Terahara3, Masashi Ando4, Yasuyuki Tsukamasa4, Teruyoshi Tanaka4, Takashi Fukuda4,5 (1. Graduate School of Agriculture, Kindai Univ., 2. Graduate School of Pharmaceutics, Kitasato Univ., 3. Graduate School of Marine Science and Technology, Tokyo Univ. Marine Science and Technology., 4. Faculty of Agriculture, Kindai Univ., 5. Agricultural Technology and Innovation Research Institute, Kindai Univ.)

[26P1-am1-061]Screening of Matrix metalloproteinase 12 (MMP-12) inhibitor in crude drug component by using in silico and in vitro method.

○Kenji Harai1, Li-kun Han1, Ryuji Takahashi1 (1. Kracie Pharma, Ltd.)

[26P1-am1-062S]Construction of CRBN plates and search for natural molecular glues that induce Tau degradation from actinomycete strains

○Naoto Enshu1, Aina Hayashi1, Toshio Hakoshima2, Shun Saito1, Midori A. Arai1 (1. Fac. Sci. Tech., Keio Univ. Univ., 2. Nara Inst. Sci. Tech. (NAIST))

[26P1-am1-063S]Construction of the extract library of marine-derived fungi: Study on the cytotoxic metabolites of the fungus Penicillium sp. from the marine sediment.

○Tokuya Teshima1, Hitora Yuuki1, Yuriko Nagano2, Sachiko Tsukamoto1 (1. Grad.Sch.Pharm.Sci., KUMAMOTO Univ., 2. JAMSTEC)

[26P1-am1-064S]Application of the cellulose plate for the isolation and cultivation of fungi to produce secondary metabolites

○Kenta Okamoto1, Yuki Hitora1, Nemuri Todaka2, Hisayo Shimizu2, Shigeru Deguchi3, Sachiko Tsukamoto1 (1. Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. KYOKUTO PHARMACEUTICAL INDUSTRIAL CO., LTD, 3. JAMSTEC)

[26P1-am1-065S]Study of sterol O-acyltransferase inhibitors produced by fungal strain BF-1093

○Rio Tejima1, Keisuke Kobayashi1,2, Yushi Uno2, Hiroshi Tomoda1, Taichi Ohshiro1,2 (1. Grad. Sch. Pharm. Sci., Kitasato Univ., 2. Sch. Pharm., Kitasato Univ)

[26P1-am1-066]Anti-glycation activity of natural compounds

○Ryuichiro Suzuki1, Aiko Sano1 (1. Fac. Pharm. Sci., Josai Univ.)

[26P1-am1-067S]Screening of Crude drugs against Vibrio vulnificus

○Hiromu Shirai1, Aiko Sano1, Hisami koito1, Ryuichiro Suzuki1 (1. Fac. Pharm. Sci., Josai Univ.)

[26P1-am1-068S]Study of an anti-Mycobacterium avium complex agent produced by marine-derived actinomycete KKMA-0239

○Miyu Kadowaki1, Satoru Shigeno1, Kanji Hosoda1, Hiroshi Tomoda1, Taichi Ohshiro1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ.)

[26P1-am1-069]Screening system to discover bioative compounds

○Tadashi Yasuhara1, Kenichiro Nagai1, Hiroshi Tomoda1, Taichi Ohshiro1 (1. Sch. Pharm., Kitasato Univ.)

[26P1-am1-070]The suppression effects of Okinawa’s local plants on human T-cell lymphotropic virus typeⅠ

○Toshiko Nasu1, Yuetsu Tanaka2, Reiko Tanaka2, Hideo Shiohira3, Jose Carlos S Tayag1, Katsunori Nakamura1,3 (1. Grad. Sch. Med., Ryukyu Univ., 2. Sch. Med., Ryukyu Univ., 3. Hosp. Pharm., Ryukyu Univ.)

[26P1-am1-071]The search for growth inhibitors of epithelial-mesenchymal transition induced cells from Curcuma longa

○Hirotaka Matsuo1, Hitomi Kawakami1, Noriaki Kawano1, Hiroyuki Fuchino1, Kayo Yoshimatsu1 (1. RCMPR)

[26P1-am1-072]Exploratory research on plants effective against extensively multidrug-resistant Mycobacterium tuberculosis.

○Hiroyuki Fuchino1, Hitomi Kawakami1, Nobuo Kawahara1,2, Kayo Yoshimatsu1, Tatsuya Tada3, Naeko MIzutani3, Fumiko Kirikae3, Keiji Funatogawa4,5, Teruo Kirikae3 (1. Res. Cen. Med. Plant Res., Nat. Inst. Biomed. Innov. Health, Nutr., 2. Kochi Pref. Makino Bot. Gard., 3. Grad. Sch. Med., Juntendo Univ., 4. Tochigi Pref. Inst. Pub. Healt. Envir. Sci., 5. Toyo foods Co., Ltd.)

[26P1-am1-073S]Screening for TGF-β signaling inhibitors from microbial origin

○Keita Beppu1, Satoshi Ohte1, Taichi Ohshiro1 (1. Sch. Pharm., Kitasato Univ.)

[26P1-am1-074S]Search for antileishmanial compounds from microbial metabolites

○Mizuki Hashimoto1, Ryo Murayama1, Yoshihiro Watanabe2,3, Mayuka Higo2,3, Kenichi Nonaka2,3, Yuki Inahashi2,3, Haruki Ishikawa1, Kiminori Ushida1, Takahiro Ishii4, Toshiaki Teruya5, Aki Ishiyama2,3, Rei Hokari2,3, Masato Iwatsuki2,3 (1. Sch. Science, Kitasato Univ., 2. Grad. Sch. Infection Control Sci., Kitasato Univ., 3. Ōmura Satoshi Memorial Instit., Kitasato Univ., 4. Fau. Agriculture, Univ. Ryukyus, 5. Sch. Education, Univ. Ryukyus)

[26P1-am1-075S]Search for substances active in the regulation of extracellular vesicle secretion from mushroom extracts.

○REI NAKAMURA1, HIRPAKI SASAKI1, MAKOTO ARAKI1, KENJI KONTANI1, KAORU KINOSHITA1 (1. Grad. Sch. Pharm. Sci., MEIJI Pharm Univ.)

[26P1-am1-076]Search for compounds that modulate the barrier function of tight junctions to enable drug delivery into the eye.

○Azusa Sumi1, Masao Hara1, Koji Miyamoto1, Misaki Ishida1, Junichiro Imamura2, Kenta Shigetomi2, Junichi Ikenouchi2 (1. NOF CORPORATION, 2. Kyushu University)

[26P1-am1-077S]A cytotoxic compound against malignant mesothelioma cells, produced by a fungus strain BF-1209

○KANA SAKAGUCHI1, SATOSHI OHTE1, TATSUHIRO SATO2, TAICHI OHSHIRO1 (1. Grad. Sch. Pharm. Sci., Kitasato Univ, 2. Aichi Cancer Cent. Res. Inst.)

[26P1-am1-078S]Search for antimalarial compounds from microbial metabolites

○So-ichiro Kimura1, Yoshihiro Watanabe1,2, Rei Hokari1,2, Aki Ishiyama1,2, Kenichi Nonaka1,2, Yuki Inahashi1,2, Masato Iwatsuki1,2 (1. Grad. Sch. Infection Control Sci., Kitasato Univ., 2. Ōmura Satoshi Memorial Inst., Kitasato Univ.)

[26P1-am1-079]Investigation of functions of Moringa oleifera leaf extract

○hiroaki tsuzuki1, katsumasa okamura1 (1. HAIR CLINIC Reve21)

[26P1-am1-080S]Bioactive secondary metabolites from shipworm endosymbionts

○Angem Librando Descallar1,2, Zhengyi Ling 1, Takuma Haga3, Tatsufumi Okino1,4 (1. Grad. Sch. Envi. Sci., Hokkaido Univ., 2. Sci. Dept.-CNSM, Mindanao State Univ.-Gen. Santos City, 3. Dept. Geol. and Paleo., Natl. Mus Nat. and Sci., 4. Fac. Envi. Earth Sci., Hokkaido Univ.)

[26P1-am1-081]Effect of 3D tissue shape on anticancer activity of essential oils

○Midori Negishi1, Narumi Iida1, Hiroaki Onoe2, Kawahara Masahiro1 (1. Pharm. Musashino Univ., 2. Sci. and Tech., Keio Univ.)
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