The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)
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Session Details

Poster Presentation(B) Pharmaceutical Physics

[26P1-am1]Radiochemistry

Sun. Mar 26, 2023 10:00 AM - 11:40 AM JST
Sun. Mar 26, 2023 1:00 AM - 2:40 AM UTC
[Room P1] Gymnasium 1F

[26P1-am1-082S]Radiosynthesis of [18F]dFTAP1 for PET imaging of fatty acid binding protein 4

○Keita Wakamori1, Anna Miyazaki1, Yasukazu Kanai1, Arisa Taguchi1, Yoichiro Ohta2, Satoru Onoe3, Hiromichi Akizawa3, Mitsunori Kirihata2, Naoya Kondo1, Takashi Temma1 (1. Grad. Sch. Pharm. Sci., Osaka Med. Pharm. Univ. , 2. Osaka Metropolitan Univ. BNCT Reserch Center, 3. Facul. Pharm., Showa Pharm. Univ.)

[26P1-am1-083S]Synthesis and evaluation of SPECT probe with 111In labeled-anti EphA2 antibody

○Minon Sasaki1, Hiroyuki Kimura1, Takenori Furukawa1, Takumu Yamada2, Takumi Iwasawa2, Kazunori Kato2, Hiroyuki Yasui1 (1. Kyoto Pharm. Univ., 2. Dept. Biomedical Engineering, Toyo Univ.)

[26P1-am1-084]Optimization of automated radiosynthesis of [18F]FSW-100, an HDAC6 PET radioligand

○Tetsuro Tago1, Jun Toyohara1, Kenji Ishii1 (1. TMIG)

[26P1-am1-085S]Research on development of [125I]EFT-7 as an imaging tracer targeting Erythropoietin-producing hepatocellular receptor A2

○takenori furukawa1, hiroyuki kimura1, chika shiga1, akane yoshimura1, yusuke yagi1,2, hidekazu kawashima1, hiroyuki yasui1 (1. Kyoto Pharm. Univ. , 2. Kyoto Pharm. Univ. Radioisotope Research Center)

[26P1-am1-086]Development of a STAT3-targeted PET imaging probe for tumor microenvironment evaluation

○Anna Miyazaki1, Karen Ishimatsu1, Yuuri Nishikawa1, Yasukazu Kanai1, Keita Wakamori1, Shinya Takada1, Fuko Hirano1, Naoya Kondo1, Takashi Temma1 (1. Grad. Sch. Pharm. Sci., Osaka Med. Pharm. Univ.)

[26P1-am1-087]Development of [11C]MeAIB synthesis on a cassette-type multipurpose automatic synthesizer module: Comparison between conventional and non HPLC procedure

○Shinya Kagawa1, Kuninori Kusano1, Miki Ito1, Ryuichi Nishii1,2, Tatsuya Higashi1,2, Chio Okuyama1 (1. Division of PET Imaging, Shiga Medical Center Research Institute, 2. Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology (QST))

[26P1-am1-088S]Development of 191Pt-labeled compounds inducing DNA damage efficiently

○Honoka Obata1,2, Atsushi B Tsuji1, Kotaro Nagatsu1, Mikako Ogawa2, Ming Rong Zhang1 (1. National Institutes for Quantum Science and Technology, 2. Grad. Sch. Pharm. Sci., Hokkaido Univ.)

[26P1-am1-089]Study on the chemical structure which is important for multivalent RGD peptides to form multiple bindings with integrin αvβ3

○Yuki Mizuno1,2, Satoru Onoe3, Miho Shukuri3, Hiromichi Akizawa3, Yuji Kuge1,2 (1. Cen. Inst. of Isot. Sci., Hokkaido Univ. , 2. Global Cen. for Biomed. Sci. and Engr., Hokkaido Univ. , 3. Showa Pharm. Univ.)

[26P1-am1-090]Preliminary screening of nanobodies for pancreatic cancer theranostics

○Takeshi Fuchigami1, Tsukasa Kosugi1,2, Yusuke Miyanari3, Ayako Tagawa3, Masayuki Munekane1, Kenji Mishiro4, Sakura Yoshida2, Akira Toriba2, Morio Nakayama2, Kazuma Ogawa1,4 (1. Grad. Sch. Pharm., Kanazawa Univ., 2. Grad. Sch. Biomed. Sci., Nagasaki Univ., 3. WPI-NanoLSI, Kanazawa Univ., 4. InFiniti., Kanazawa Univ.)

[26P1-am1-091]Fully automated radiosynthesis of selective monoamine oxidase B tracer [18F]SMBT-1 for clinical use

○JUN TOYOHARA1, Tetsuro Tago1, Kosuke Nishino1,2, Masanari Sakai1,2, Kenji Ishii1 (1. TMIG, 2. SAS)

[26P1-am1-092S]Development of nuclear medical imaging probe for systemic amyloidosis: drug design to reduce nonspecific accumulation in normal tissues

○Yoshie Haratake1, Kohei Sano1, Chika Fujioka1, Satsuki Oshima1, Masayuki Munekane1,2, Toshihide Yamasaki1, Takahiro Mukai1 (1. Kobe Pharm. Univ., 2. Grad. Sch. Pharm., Kanazawa Univ.)

[26P1-am1-093S]Synthesis and evaluation of 111In-DOTA-bradykinin analogue for bradykinin B1 receptor imaging.

○Tsubasa Karube1, Miho Shukuri1, Satoru Onoe1, Risa Mokudai1, Hayate Wakui1, Haruka Asano1, Shin Murai1, Hiromichi Akizawa1 (1. Showa Pharm. Univ.)

[26P1-am1-094]Effect of X-ray, proton, and carbon irradiation therapies on cervical cancers and early detection of their therapeutic effects by PET using 18F-FLT as an imaging tracer

○AKIRA MAKINO1, KYO KUME2, TETSUYA MORI1, HIDEHIKO OKAZAWA1, YASUSHI KIYONO1 (1. Biomedical Imaging Research Center, University of Fukui, 2. The Wakasa-Wan Energy Research Center)

[26P1-am1-095]Accelerated blood clearance of radiolabeled antibody using click chemistry

○Hirofumi Hanaoka1,2, Citra RAPP Palangka2, Ayaka Kanai2, Natsumi Katsumata2, Hiroyuki Suzuki3, Tomoya Uehara3, Yoshito Tsushima2 (1. Kansai Medical Univ., 2. Grad. Sch. Med., Gunma Univ., 3. Grad. Sch. Pharm. Sci., Chiba Univ.)

[26P1-am1-096]Development of radio-synthesis of 3-[18F]fluoro-α-methyl-L-tyrosine by nucleophilic fluorination with [18F]HF

○Naka Sadahiro1,2, Watabe Tadashi1, Ohta Yoichiro3, Kurimoto Kenta1,2, Kinoshita Daisuke4, Wakahara Masaharu4, Yasuda Yuta4, Tatsumi Mitsuaki1, Shimosegawa Eku1, Kirihata Mitsunori3, Kato Hiroki1 (1. Grad. Sch. Med., Osaka Univ., 2. Osaka Univ Hosp., 3. BNCT Res. Cent., Osaka Metropolitan Univ., 4. SHI Accelerator Service)

[26P1-am1-097S]Affinity Evaluation of Cystine-dense peptide TfRB1G3 for TfR1 and synthesis of HBED-CC conjugate for 68Ga labeling.

○Lin Longxin1, Mizuno Yuki2,3, Kuge Yuji2,3, Shibata Yuki3, Yasui Hironobu4 (1. Grad. Sch. Biomed. Sci. and Engr., Hokkaido Univ., 2. Cen. Inst. of Isot. Sci., Hokkaido Univ., 3. Global Cen. for Biomed. Sci. and Engr., Hokkaido Univ., 4. Fac. Vet. Med., Hokkaido Univ.)

[26P1-am1-098S]Effect of the number of RGD peptides introduced into albumin dimer on its in vivo behavior.

○Mao Sugita1, Satoru Onoe1, Kazuki Ooi1, Yurika Kumakawa1, Mizuki Kaneko1, Yuki Mizuno2,3, Miho Shukuri1, Hiromichi Akizawa1 (1. Showa Pharm. Univ., 2. Cen. Inst. of Isot. Sci., Hokkaido Univ., 3. Global Cen. for Biomed. Sci. and Engr.)

[26P1-am1-099S]Development of Glyoxalase I-targeted SPECT probes: metabolism of radioiodinated glutathione analogue-diester in cells

○Shiori Oba1, Satoru Onoe1, Kano Takadou1, Yuki Mizuno2,3, Miho Shukuri1, Hiromichi Akizawa1 (1. Showa Pharmaceutical Univ., 2. Cen. Inst. of Isot. Sci., Hokkaido Univ., 3. Global Cen. for Biomed. Sci. and Engr.)

[26P1-am1-100]Establishment of synthesis method of 11C acetic acid using cassette type synthesizer and solid-phase extraction column

○KENTA KURIMOTO1,2, SADAHIRO NAKA1,2, MASAHARU WAKAHARA3, DAISUKE KINOSHITA3, YUTA YASUDA3, HIROKI KATO2 (1. Department of Pharmacy, Osaka University Hospital, 2. Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 3. SHI Accelerator Service)

[26P1-am1-101S]Radioprotective effect of bone marrow cell by extracellular nucleotides

○Ayu Moriya1, Kazuki Kitabatake1, Mitsutoshi Tsukimoto1 (1. Faculty of Pharm. Sci., Tokyo Univ. Sci.)

[26P1-am1-102]Specific radiation sensitization effect on cancer cells and radiation protection effect on normal cells via regulation of purinergic receptor activity

○Kazuki Kitabatake1, Mitsutoshi Tsukimoto1 (1. Faculty of Pharm Sci, Tokyo Univ. Sci.)

[26P1-am1-103S]Involvement of FROUNT in gamma-irradiation-induced cell migration in human lung cancer A549 cells

○Saya Tazawa1, Yuya Terashima2, Kazuki Kitabatake1, Mitsutoshi Tsukimoto1 (1. Faculty. Pharm. Sci., Tokyo Univ. Sci., 2. Grad. Sch. Biol. Sci., Tokyo Univ. of Sci.)

[26P1-am1-104]Local concentration of hydroxyl radical and hydrogen radical generated in water by X-ray irradiation and the effect of oxygen on the generation of those radical species

○Ken-ichiro Matsumoto1, Yusuke Makino1,2, Megumi Ueno1, Yoshimi Shoji1,3, Hiromu Ito3, Nakanishi Ikuo3, Koji Fukui2 (1. NIRS, QST, 2. Grad. Sch. Eng. Sci, Shibaura Inst. Tech., 3. Inst. Quantum Life Sci., QST)

[26P1-am1-105]Analysis of subcellular localization of APOBEC3B after DNA damage

○Yohei Saito1, Momoka Saito1, Erina Fukushima1, Yumi Yamamoto1, Fumihiko Yamamoto1 (1. Pharm. Sci., Tohoku Med. Pharm. Univ.)

[26P1-am1-106S]Effect of X ray-irradiation on amyloid-β-induced cytotoxicity

○Yuuka Nitta1, Nakamura yuki1, Kobayashi Yoshiko1, Umeda tomonobu1, katou Shinsuke1 (1. YOKOHAMA UNIVERSITY OF PHARMACY)

[26P1-am1-107]Inhibition of cell death progression by X-ray irradiation

○Yuki Nakamura1, Yuka Nitta1, Kayo Aragaki1, Nayu Hatano1, Tomoko Matsuda1, Yuna Miyazawa1, Yudai Takagi1, Tomonobu Umeda1, Yoshiko Kobayashi1, Shinsuke Katoh1 (1. Yokohama University of pharmacy)

[26P1-am1-108]Suppression of cell death by X-ray irradiation in cerebral ischemia-reperfusion model

○Kayo Arakaki1, Yudai Takagi1, Yuna Miyazawa1, Tomoko Matsuda1, Nayu Hatano1, Yuki Nakamura1, Kobayashi Yoshiko1, Umeda Tomonobu1, Kato Shinsuke1 (1. Yokohama University Of Pharmacy)

[26P1-am1-109S]In vitro and in vivo evaluation of boron drugs targeting Glucose transporter for BNCT

○Fumi Kimura1, Seina Terada1, Yuhki Sato1, Minoru Suzuki2, Takayuki Kanaya3, Makoto Shirakawa1,4 (1. Pharm. Sci., Fukuyama Univ. , 2. Institute for Integrated Radiation and Nuclear Science, Kyoto Univ., 3. Pharm. Sci., Int. Univ. Health and Welfare, 4. Faculty of Medicine, Tsukuba Univ.)

[26P1-am1-110S]Development of Ionic Liquids Composed of BPA for Boron Neutron Capture Therapy

○Saki Kawamoto1, Sayaka Kawakami1, Tomonori Sakai1, Riko Terada1, Mimori Samejima1, Yuhki Sato1, Hiroaki Kumada2, Takeji Sakae2, Akira Matsumura2, Nobuyuki Kamegawa3, Ryota Takeuchi3, Hitoshi Hori3, Minoru Suzuki4, Makoto Shirakawa1,2 (1. Pharm. Sci., Fukuyama Univ., 2. Faculty Medicine, Tsukuba Univ., 3. Morita Pharmaceutical Ind.,Ltd, 4. Institute for Integrated Radiation and Nuclear Science, Kyoto Univ.)

[26P1-am1-111]Low dose radiation therapy of COVID-19

○Noriko Shimura1, Koki Mochizuki1, Shuji Kojima2 (1. Faculty of Pharmaceutical Sciences, Ohu University, 2. Faculty of Pharmaceutical Sciences, Tokyo University of Science)

[26P1-am1-112]Glial energy metabolism in the neonatal mouse brain during convulsive seizures using intranasal administration.

○Rie Hosoi1, Kenya Tada1, Takahiro Hayakawa1, Yuka Haga1, Atsushi Tamura1, Makoto Osanai1 (1. Grad. Sch. Med., Osaka Univ.)

[26P1-am1-113S]Kinetic analysis on transporter-mediated cellular uptakes of 3-boronophenylalanine derivatives

○Fuko Hirano1, Naoya Kondo1, Yusuke Murata2, Aya Sudani2, Takashi Temma1 (1. Grad. Sch. Pharm. Sci., Osaka Med. Pharm. Univ., 2. Stella Pharma Co.)

[26P1-am1-114S]Development of a red-emitting fluorescence sensor for detecting boronic acid-containing agents in cells

○Erika Aoki1, Naoya Kondo1, Shinya Takada1, Takashi Temma1 (1. Facul. Pharm., Osaka Med. Pharm. Univ.)
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