The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)
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Session Details

Poster Presentation(B) Pharmaceutical Physics

[27P2-pm1]Functional polymers/Physical properties of pharmaceuticals/Biological membrane and artificial model membrane/Pharmaceutical physical chemistry/Others

Mon. Mar 27, 2023 1:50 PM - 3:30 PM JST
Mon. Mar 27, 2023 4:50 AM - 6:30 AM UTC
[Room P2] Gymnasium 1F

[27P2-pm1-001S]Protein encapsulation in polypeptide-based cyto-mimetic complex coacervates via polymer charge-density tuning

○Haya Kadan1, Biplab KC1, Teruki Nii2, Takeshi Mori2,3, Yoshiki Katayama2,3,4,5, Akihiro Kishimura2,3,4,6 (1. Grad. Sch. Systems Life Sciences, Kyushu Univ., 2. Dep. Applied Chem., Fac. Eng., Kyushu Univ., 3. Center for Future Chem. (CFC), Kyushu Univ., 4. Center for Mol. Sys. (CMS), Kyushu Univ., 5. Center for Adv. Med.l Open Innovation, Kyushu Univ, 6. RIKEN Center for Emergent Matter Sci.)

[27P2-pm1-002S]Drug loading and sustained release on surface modified acrylate polymers by photo-oxidation using chlorine dioxide

○Hitomi Nakagawa1, Haruyasu Asahara1,2, Kazuo Harada1, Koichi Baba3, Kei Ohkubo2,4, Tsuyoshi Inoue1,2, Koji Nishida2,3 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. OTRI, Osaka Univ., 3. Grad. Sch. Med., Osaka Univ., 4. IACS, Osaka Univ.)

[27P2-pm1-003S]Improvement of cell affinity for poly(lactic acid) surface by photo-oxidative modification using chlorine dioxide

○Nana Otsuka1, Haruyasu Asahara1,2, Akihiro Nishiguchi3, Tetsushi Taguchi3, Tsuyoshi Inoue1,2 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. OTRI, Osaka Univ., 3. NIMS)

[27P2-pm1-004]Development of BSH/CP Nanoparticle for Boron Neutron Capture Therapy.

○Tomohiro Tanaka1,2, Ueda Hiroki2,3, Suzuki Minoru3, Sakurai Yoshinori3, Ueda Masashi1, Aoki Shin2,4 (1. Graduate school of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 3. Institute for Integrated Radiation and Nuclear Science, Kyoto University, 4. Research Institute for Science and Technology, Tokyo University of Science)

[27P2-pm1-005S]Functionalization of graphene for observation of protein by Cryo-EM

○Seina Yarimizu1, Haruyasu Asahara1,2, Maiko Moriguchi1, Tsuyoshi Inoue1,2 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. OTRI, Osaka Univ.)

[27P2-pm1-006]Preparation of lecithin reverse wormlike micelles containing water-soluble polymers using solid polar substances

○Kaname Hashizaki1, Nozomi Komori1, Osamu Sakata1, Junya Yamamoto1, Yasuhiro Kosuge1, Hiroyuki Taguchi1, Makiko Fujii1 (1. Sch. Pharm., Nihon Univ.)

[27P2-pm1-007]Preparation of layer by layer thin film composed of dendrimer containg Rose Bengal in the presence of KCl, KNO3 or Na2SO4

○Shigehiro TAKAHASHI1, Kairi Yamada1, Iwao Suzuki1 (1. Grad. Sch. Pharm., takasaki Univ. of health and welfare )

[27P2-pm1-008]Synthesis of rod-shaped and spherical nanomaterials with different sizes and considerations on the nanomaterial-shape effects on the protein corona formation

○Akane Shinaridome1, Erina Kurome1, Kunisato Kuroi1, Fumihiko Fujii1 (1. Fac. Pharm. Sci., Kobegakuin Univ.)

[27P2-pm1-009]Shape effects of nanomaterials on protein corona formation and thermodynamic considerations

○Yuta Kanazawa1, Masato Sannomiya1, Kunisato Kuroi1, Fumihiko Fujii1 (1. Fac. Pharm. Sci., Kobegakuin Univ.)

[27P2-pm1-010]Dispersion stability of iron oxide nanoparticles by zwitterionic molecules as a dispersant in water

○Takahiro Sasaki1, Kouki Aihara1, Mei Gotoda1, Yujiro Sato1, Yuzu Yamashiro1, Miho Hashimoto1, Takuto Inoue1, Kousuke Sato1, Tsuyoshi Murai1 (1. Sch. Pharm. Sci., Health Sci. Univ. of Hokkaido)

[27P2-pm1-011]Inclusion Compound of Daidzein with Cyclodextrin-Based Metal–Organic Framework-1 for Enhanced Solubility and Antioxidant Capacity

○Yutaka Inoue1, Masaaki Yoshida1, Toshinari Ezawa1, Takashi Tanikawa1, Junki Tomita2, Mitsuaki Suzuki3, Toshio Oguchi4 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, 2. Instrument Analysis Center, Josai University, 3. Faculty of Science, Josai University, 4. Graduate School of Medicine, University of Yamanashi)

[27P2-pm1-012S]Approach to the preparation of Honokiol solid dispersions and their solubility in the Cortex of Magnoliae.

○Kaede Yoshino1, Takami Yokogawa1, Masashi Kitamura1, Takashi Tanikawa1, Yutaka Inoue1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Josai University)

[27P2-pm1-013]Investigation of physical properties of disodium etidronate tetrahydrate and application of phosphorus K-edge X-ray absorption near-edge structure spectroscopy

○Naoya Ito1, Takahiko Hashizuka2, Masataka Ito3, Hironori Suzuki3, Shuji Noguchi3 (1. Sumitomo Pharma, 2. Sumitomo Dainippon Pharma (Former company name), 3. Toho Univ.)

[27P2-pm1-014]Research on the crystalline forms of TRK-170, a therapeutic agent for inflammatory

○Hirozumi Takahashi1, Tsutomu Nogami1, Motohiro Shiraki1 (1. Toray Industries, Inc.)

[27P2-pm1-015]Real-time in situ X-ray micro-computed tomography study of the effect of impurities on the crystallization of amorphous nifedipine

Yuta Amano1, Takashi Misawa2, Tamaki Miyazaki2, Daisuke Ando2, Hideko Kanazawa1, Kenjiro Hanaoka1, ○Eiichi Yamamoto2 (1. Faculty of Pharmacy, Keio University, 2. National Institute of Health Sciences)

[27P2-pm1-016S]Development of biomimetic mucus for evaluating mucus diffusion process of orally administered drug

○Shota Soga1,2, Kohsaku kawakami1,2 (1. National Institute for Materials Science, 2. Graduate School of Pure and Applied Sciences, University of Tsukuba)

[27P2-pm1-018]The effect of alpha radioactive nucleus on the structure of antibody drugs

○Shoko Ohashi1, Mitsuyoshi Yoshimoto2, Teppei Shimizu1,3, Daisuke Takakura1, Hirofumi Fujii2,4, Akiko Hachisuka5, Nana Kawasaki1 (1. Grad. Sch. of Medical Life Sci., Yokohama City Univ., 2. Natl.Cancer Ctr. Res. Inst., 3. KISSEI Pharm CO.,LTD., 4. Japan RI. Association., 5. Natl. Health Science Inst.)

[27P2-pm1-019]Involvement of transporters in cellular transport of antitumor-active dinuclear platinum(II) complex

○Masako Uemura1, Seiji Komeda1 (1. Fac. Pharm. Sci., Suzuka Univ. Med. Sci.)

[27P2-pm1-020S]Synthesis and characterization of terminal alkyne-introduced tetrazolato-bridged dinuclear platinum(II) complexes

○Miki Wakayama1, Hiroki Yoneyama2, Masako Uemura1, Yoshihide Usami2, Seiji Komeda1 (1. Fac. Pharm. Sci., Suzuka Univ. Med. Sci., 2. Fac. Pharm., Osaka Med. Pharm. Univ.)

[27P2-pm1-021S]Reactions of mononucleotides with the highly cytotoxic azolato-bridged dinuclear Pt(II) complex effective against cisplatin-resistant cancer

○Takuma Yamada1, Seiji Komeda1 (1. Fac. Pharm. Sci., Suzuka Univ. Med. Sci.)

[27P2-pm1-022]Binary monolayers of a tetrazine-containing gemini amphiphile

○Hiromichi Nakahara1, Masayori Hagimori2, Takahiro Mukai3, Osamu Shibata4 (1. Daiichi Univ. Pharm., 2. Mukogawa Women’s Univ., 3. Kobe Pharm. Univ., 4. Nagasaki Intl. Univ.)

[27P2-pm1-023S]Development of membrane protein delivery technology using lipid-peptide Nanodisc

○Kanako Ikadai1, Keisuke Ikeda1, Hiroyuki Nakao1, Minoru Nakano1 (1. Fac. Pharm. Sci., Toyama Univ.)

[27P2-pm1-024S]Implantation of exosomal membrane proteins to recipient cells and artificial regulation techniques

○Jojiro Ishitobi1, Tomoka Takatani-Nakase2,3, Ikuhiko Nakase4 (1. Col. of Life, Env., and Adv. Sci., Osaka Metropolitan Univ., 2. Grad Sch. Pharm. Sci., Mukogawa Women’s Univ., 3. Inst. for Biosci., Mukogawa Women’s Univ., 4. Grad Sch. Sci, Osaka Metropolitan Univ.)

[27P2-pm1-025S]Control of flip-flop promoting activity of peptides by multimerization

○Taichi Yamamoto1, Hiroyuki Nakao1, Keisuke Ikeda1, Minoru Nakano1 (1. Fac. Pharm. Sci., Univ. Toyama)

[27P2-pm1-026S]Inhibition of mast cell activation by gene delivery using cationic liposomes

○Ayaka Yamamoto1, Yoshikazu Inoh2, Ruriko Suzuki1, Tadahide Furuno2, Naohide Hirashima1 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ., 2. Sch. Pharm., Aichi Gakuin Univ.)

[27P2-pm1-027]Importance of two-dimensional cation cluster structure formation by folding in protein cell membrane permeation

○Mami Hamori1, Yuka Nakagawa2, Miki Imanishi3, Miku Kurehara4, Chieri Kitada4, Masato Mashimo4, Shibata Nobuhito4, Shigeru Negi4 (1. Kitasato University School of Pharmacy, 2. Graduate School of Life Science, University of Hyogo, 3. Institute for Chemical Research, Kyoto University, 4. Doshisha Women's College of Liberal Arts)

[27P2-pm1-028]Basic study on the mechanism of liposomal internalization into alveolar macrophages models.

Ryoya Ibuki1, Shun Tokui1, ○Toshihiko Sugiki1, Kanji Hosoda1, Hiroshi Tomoda1, Kumiko Sakai-Kato1 (1. Sch. Pharm., Kitasato Univ.)

[27P2-pm1-029]Formation of nuclei during annealing impeded the supersaturation in the dissolution process of celecoxib glass

○JINGWEN SONG1, KOHSAKU KAWAKAMI1,2 (1. National Institute for Materials Science (NIMS), 2. Graduate School of Pure and Applied Sciences, University of Tsukuba)

[27P2-pm1-030]Analysis of T1 relaxation by Akaike information criterion to evaluate the miscibility of amorphous solid dispersions

○Kotaro Okada1, Yoshihiro Hayashi2, Shungo Kumada2, Yoshinori Onuki1 (1. School of Pharmacy and Pharmaceutical Sciences, University of Toyama, 2. Nichi-Iko Pharmaceutical Co., Ltd.)

[27P2-pm1-031S]Characterization of glyclopyramide cocrystal by X-ray absorption near edge structure spectra

○Yosuke Kimura1, Shiori Sakamoto1, Hironori Suzuki1, Masataka ito1, Shuji noguchi1 (1. Faculty of Pham. Sci., Toho Univ.)

[27P2-pm1-032S]Monitoring the crystal shape of pharmaceuticals during wet granulation using Low Frequency Raman Spectroscopy

○Mayu Ono1, Koki Otaka1, Narumi Aiba1, Toshiro Fukami1 (1. Meiji Pharm. Univ.)

[27P2-pm1-033]Monitoring the Dissolution Behavior of Artemisinin Cocrystals with Probe-type Low-frequency Raman Spectrometer

○Takayuki Kudo1, Soichiro Miura1, Varin Titapiwanakun2, Toshiro Fukami1 (1. Meiji Pharm Univ., 2. Pharm. Sci., Chulalongkorn Univ.)

[27P2-pm1-034S]Analysis of intermolecular interaction in solid dispersions using fibrates by X-ray absorption near-edge structure spectroscopy

○Haruhi Magara1, Yuta Kuwahara1, Hironori Suzuki1, Masataka Ito1, Shuji Noguchi1 (1. Faculty of Pharm. Sci., Toho Univ.)
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