The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo)
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Session Details

Poster Presentation(A) Pharmaceutical Chemistry

[28P1-am2]Isolation/Structural Determination 2

Tue. Mar 28, 2023 10:50 AM - 12:30 PM JST
Tue. Mar 28, 2023 1:50 AM - 3:30 AM UTC
[Room P1] Gymnasium 1F

[28P1-am2-001]Bioactive constituents of Lindernia crustacea with anti-EBV effect

Yu-Chi Tsai1, Mohamed El-Shazly2,3, Li-Kwan Chang4, Attila Hunyadi5, Fang-Rong Chang6, ○Yang-Chang Wu7,8,9 (1. School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, 2. Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Organization of African Unity Street, Abassia, 11566, Cairo, Egypt, 3. Department of Pharmaceutical Biology, Faculty of Pharmacy and Biotechnology, The German University in Cairo, 11835, Cairo, Egypt, 4. Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, 106, Taipei, Taiwan, 5. Department of Pharmacognosy, University of Szeged, 6720, Szeged, Hungary, 6. Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, 807, Kaohsiung, Taiwan, 7. Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, 8. Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung, Taiwan, 9. The Biotechnology Department, College of Medical and Health Science, Asia University, Taichung, Taiwan)

[28P1-am2-002]Search for Aβ aggregation inhibitory active compounds from Polyozellus multiplex MeOH extract and neuroprotective effects

○shoko nakabayashi1, Ayaka Ishikura1, Koji Fujihara1, Shuntaro Hirabayashi1, Shin Koike1, Hiroaki Sasaki1, Yuki Ogasawara1, Kiyotaka Koyama1, Kaoru Kinoshita1 (1. Meiji Pharm. Univ.)

[28P1-am2-003]Production mechanism of black tea thearubigins

Keigo Hashiguchi1, Yosuke Matsuo1, Yoshinori Saito1, ○Takashi Tanaka1 (1. Grad. Sch. Biomed. Sci., Nagasaki University)

[28P1-am2-004]Oxidative oligomerization of dihydrochalcone glycoside

○ZHANGBIN LIU1,2, YOSUKE MATSUO1, YOSHINORI SAITO1, YONGLIN HUANG2, DIANPENG LI2, GENICHIRO NONAKA 3, TAKASHI TANAKA1 (1. Grad. Sch. Biomed. Sci., Nagasaki Univ., 2. Guangxi Inst. Bot., 3. Usaien Pharm. Ltd)

[28P1-am2-005]Search for Natural Compounds that Inhibit the Formation of Advanced Glycation End-products from Humulus Lupulus.

○Keisuke Nakashima1, Yukihiro Miyashita1, Hitoshi Yoshimitsu1, Yukio Fujiwara2, Ryoji Nagai3, Tsuyoshi Ikeda1 (1. Facul. Pharm. Sci. Sojo Univ., 2. Grad. Sch. Med. Sci. Kumamoto Univ., 3. Sch. Agric. Tokai Univ.)

[28P1-am2-006]Structure elucidation of two new xanthones from Calophyllum soulattri (Guttiferae) and the inhibitory effect of human cancer cell proliferation of the isolated compounds

○Chihiro Ito1, Yuta Kato1, Takuya Matsui1,2, Masataka Itoigawa3, Hugh Tan4 (1. Faculty of Pharmacy, Meijo Univ., 2. Aichi Medical Univ., 3. Tokai Gakuen Univ., 4. Singapore Univ.)

[28P1-am2-007]Search of SOAT2 selective inhibitor by focusing on product ion of mass spectrometry

○Reiko Seki1, Kenichiro Nagai1, Hiroshi Tomoda1, Taichi Ohshiro1 (1. Sch. Pharm., Kitasato University)

[28P1-am2-008S]Exploration of osteogenesis-promoting active constituents from the branch of Maackia tashiroi with estrogen receptor transcription promoting activity

○Misaki Watanabe1, Tadahiro Yahagi1, Haruto Fukutomi1, Sae Igarashi1, Hitoshi Kotani2, Katsunori Miyake3, Keiichi Matsuzaki1 (1. Sch. Pharm., Nihon Univ., 2. Fac. Med., Shimane Univ., 3. Sch. Pharm., Tokyo Univ. Pharm. Life Sci.)

[28P1-am2-009]Synthesis of sancti derivatives via chalcone derivatives and evaluation of their monoamine oxidase inhibitory activity

○Fumiya Takahashi1, Hitoshi Kamauchi1, Kouichi Takao1, Yoshiaki Sugita1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Josai University)

[28P1-am2-010S]Search for natural products with BMI1 promoter inhibitory activity from Caesalpinia digyna

○Kazuki Fujii1, Yasumasa Hara1,2, Akiko Takaya1,2,3, Firoj Ahmed4, Samir K. Sadhu5, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Med. Mycol. Res. Cent., Chiba Univ., 4. Dept. Pharm. Chem., Dhaka Univ., 5. Pharmacy Discipline, Khulna Univ.)

[28P1-am2-011S]Total Synthesis of Mangostins

○Haruka Shiga1, Miho Mochizuki1, Yuuki Fujimoto1, Hikaru Yanai1, Takashi Matsumoto1 (1. Tokyo University of Pharmacy and Life Sciences)

[28P1-am2-012]Search for natural products from Xylia kerri with cytotoxicity for rheumatoid fibroblast-like synoviocytes

○Yasumasa Hara1,2, Itsuki Iwata1, Kazuki Fujii1, Yuki Matsuoka1, Akiko Takaya1,2,3, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci, Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Med. Mycol. Res. Cent., Chiba Univ.)

[28P1-am2-013S]Synthesis of Grifolin derivatives and their inhibitory activity against Candida albicans hyphae formation

○Fumihito Wakaura1, Hiroaki Sasaki1, Sanae Kurakado1, Ayumu Hirabayashi1, Takashi Sugita1, Kiyotaka Koyama1, Kaoru Kinoshita1 (1. Meiji Pharm. Univ.)

[28P1-am2-014]Identification of anti-inflammatory and UV-protective substances in Tamanu oil (Calophyllum inophyllum seed oil) from Okinawa

○Takayuki Ogi1, Yasuhiro Kawano2, Papawee Saiki2, Idam Hermawan1, Hiroto Yokaryo1, Toru Usami3 (1. OITC, 2. AIST, 3. Smaeco)

[28P1-am2-015]Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants

○Daisuke Nakano1, Kenji Ishitsuka2, Yurie Deishi1, Ryota Tsuchihashi1, Masafumi Okawa1, Junei Kinjo1 (1. Fukuoka University, 2. Kagoshima University)

[28P1-am2-016S]Studies on the constituents of Coix lacryma-jobi L. var. ma-yuen Stapf from Myanmar (3)

○Mayu Terada1, Kazuki Okoshi1, Reina Miyake1, Akira Sato1, Naohiro Oshima1,2, Noriyasu Hada1 (1. Faculty of Pharm. Sci., Tokyo Univ. Sci., 2. Natl. Inst. Health Sci.)

[28P1-am2-017]Development of endogenous vitamin D3 hydroxide synthesis method by using in situ generation of dioxirane

○Shoujiro Ogawa1, Asahi Honjyo1, Rikako Morichika1, Yuko Date1, Naoko Narahara1, Hirofumi Inioue1, Eijiro Kojima1 (1. Facul. Pharmacy and Pharm. Sci. Fukuyama Univ.)

[28P1-am2-018S]Cleaved steroids from fruiting bodies of Pleurotus cornucopiae var. citrinopileatus

○Sari Minato1, Takashi Kikuchi1, Kouharu Otsuki1, Takeshi Yamada2, Tomoya Hirano2, Wei Li1 (1. Faculty of Pharm. Sci., Toho University, 2. Faculty of Pharm., Osaka Med. Pharm. Univ.)

[28P1-am2-019S]Structural characterization of novel steroidal glycosides from the bulbs of Ornithogalum thyrsoides and their cytotoxicity

○Naoki Takahashi1, Tomoki Iguchi1, Kaito Nakamura1, Yukako Sano1, Yoshihiro Mimaki1 (1. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)

[28P1-am2-020S]Chemical components of Ranunculaceae plants (39)
Apoptosis-inducing activity of bufadienolide derivative from the whole plants of Helleborus niger

○Yuka Yoshizawa1, Mina Inomata1, Akihoto Yokosuka1, Tomoki Iguchi1, Yoshihiro Mimaki1 (1. Tokyo University of Pharmacy and Life Sciences)

[28P1-am2-021S]Search for natural products suppressing NO production from the genus Nocardia

○Mami Miyake1, Yasumasa Hara1,2, Keiichiro Watanabe1, Akiko Takaya1,2,3, Takashi Yaguchi3, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Med. Myc. Res. Cent., Chiba Univ.)

[28P1-am2-022S]Inhibitors of Candida albicans Dimorphism from Arthrinium sp. No. 3

○Takato Ishida1, Nanae Kuroki1, Sanae Kurakado1, Hiroaki Sasaki1, Takashi Sugita1, Kiyotaka Koyama1, Kaoru Kinoshita1 (1. Grad. Sch. Pharm. Sci., Meiji Pharmaceutical Univ.)

[28P1-am2-023]HIV-1 latency reversal activity and the constituents from Euphorbia usambarica Pax.

○Yu-Chi Tsai1,2, Racheal A. Nell3, Jonathan E. Buckendorf3, Norbert Kúsz2, Adam M. Spivak3, Judit Hohmann2,4 (1. School of Chinese Medicine, China Medical University, Taichung 404328, Taiwan., 2. Interdisciplinary Excellence Centre, Department of Pharmacognosy, University of Szeged, H-6720 Szeged, Hungary, 3. Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA, 4. Interdisciplinary Centre of Natural Products, University of Szeged, H-6720 Szeged, Hungary)

[28P1-am2-024]Seven previously undescribed metabolites from the bark of Chamaecyparis formosensis Matsum

Ming-Jen Cheng1, Yu-Cheng Lu2, Che-Hung Kuo2, Yu-Chang Chen3, Jih-Jung Chen4,5, Ching-Kuo Lee6,7,8, Che-Yi Chao9, Hui-Chi Huang10, ○Yueh-Hsiung Kuo10,11,12 (1. Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), Hsinchu 300, Taiwan, 2. Department of Chemistry, National Taiwan University, Taipei 106, Taiwan, 3. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan, 4. Department of Pharmacy, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University (NYCU), Taipei 112, Taiwan, 5. Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan, 6. Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei 11031, Taiwan, 7. Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei 110301, Taiwan, 8. School of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan, 9. Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan, 10. Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University, Taichung 404, Taiwan, 11. Department of Biotechnology, Asia University, Taichung 413, Taiwan, 12. Chinese Medicine Research Center, China Medical University, Taichung 404, Taiwan)

[28P1-am2-025]Neritriterpenols H-N, Anti-inflammatory Euphane-type Triterpenes from Euphorbia neriifolia L.

Stephen S. Chang1,2, Hung-Tse Huang1, Yu-Chi Lin1, I-Wen Lo1, Hui-Chi Huang3, Hui-Chun Wang4, Yao-Haur Kuo1, ○Chia-Ching Liaw1,5 (1. Division of Materia Medica Development, National Research Institute of Chinese Medicine, MOHW, Taipei 112, Taiwan, 2. Ph.D. Program in Clinical Drug Development of Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan, 3. Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan, 4. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, 5. Department of Biochemical Science and Technology, National Chiayi University, Chiayi 600, Taiwan)

[28P1-am2-026S]Research of constituents from Isodon trichocarpus (Labiatae) with antiproliferative activities aganinst cancer stem cells

○Momona Nakao1, Sachiko Sugimoto1,2, Takahiro Matsumoto1, Souichi Nakashima1, Hisashi Matsuda1, Seikou Nakamura1 (1. Kyoto Pharmaceutical University, 2. Graduate School of Biomedical and Health Sciences, Hiroshima University)

[28P1-am2-027]Revisiting the Stereostructure of 1β,10β-Epoxyeremophilenolide Derivatives from Asteraceae Plants

○Yasunori Yaoita1, Koichi Machida1 (1. Pharm. Sci., Tohoku Med. Pharm. Univ.)

[28P1-am2-028S]Structure and biological activity of diterpens from Salvia and Euphorbia species in Hengduan Mountains

○Yuuto Nakamura1, Koki Sekigutchi1, Mai Okamoto1, Yasuko Okamoto2, Keiichi Matsuzaki3, Xun Gong4, Ayumi Ohsaki1 (1. College of Humanities and Sciences, Nihon University, 2. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 3. School of Pharmacy, Nihon University, 4. Kunming Institute of Botany)

[28P1-am2-029S]A hydroxynerol derivative isolated form Artemisia sieversiana

○Nurbyek Stipan1,2, Toshihiro Murata1, Kenroh Sasaki1, Javzan Batkhuu2 (1. Division of Pharmacognosy, Tohoku Medical and Pharmaceutical University, 2. School of Engineering and Applied Sciences, National University of Mongolia)

[28P1-am2-030]Chemical constituents of Penicillium meridianum VBP6, an Ericaceae plant-derived endophytic fungus

Rintaro Shima1, Dai Hirose2, ○Kan'ichiro Ishiuchi1 (1. Grad. Sch. Pharm. Sci., Nagoya City Univ., 2. Sch. Pharm., Nihon Univ.)

[28P1-am2-031]Novel 14-membered marcolides from an octocoral Sinularia sp.

Hsuan-Jung Tseng1,2, ○Li-Guo Zheng1,3, Yuan-Bin Cheng4, Ping-Jyun Sung1,3,4 (1. National Museum of Marine Biology & Aquarium, Pingtung 944401, Taiwan, 2. Graduate Institute of Marine Biology, National Dong Hwa University, Hualien 974301, Taiwan, 3. Doctoral degree Program in Marine Biotechnology, National Sun Yat-Sen University, Kaohsiung 804201, Taiwan, 4. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804201, Taiwan)

[28P1-am2-032S]Discovery of new briarane-diterpenoids from the Okinawan octocoral Briareum stechei and their anti-inflammatory activity

○Huynh Thanh Hao1,2, Chih-Chuang Liaw1, Ping-Jyun Sung1,2 (1. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804201, Taiwan, 2. National Museum of Marine Biology and Aquarium, Pingtung 944401, Taiwan)

[28P1-am2-033]Improving effect on lipid metabolism of 7-deacetoxy-7-oxogedunin, a limonoid from Andiroba (Carapa guianensis), and it’s mode of action

○Akifumi Nagatomo1, Kiyofumi Ninomiya1,2, Shinsuke Marumoto3, Chie Sakai1, Shuta Watanabe1, Wakana Ishikawa1, Yoshiaki Manse1, Takashi Kikuchi4,5, Takeshi Yamada4, Reiko Tanaka4, Osamu Muraoka1,6, Toshio Morikawa1,6 (1. Pharm. Res. Technol. Inst., Kindai Univ., 2. Sch. Pharm., Shujitsu Univ., 3. Joint Res. Ctr., Kindai Univ., 4. Fac. Pharm., Osaka Med. Pharm. Univ., 5. Fac. Pharm., Toho Univ., 6. Antiaging Ctr., Kindai Univ.)

[28P1-am2-034S]Search for substances that promote exosome production for creation of new cosmetic materials.

○Kohei Sato1, Jianyu LIN1, Hongqiang LIN1,2, Jinping LIU2, Chitose Oneyama3, Masayoshi Arai1 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Sch. Pharm. Sci., Jilin Univ., 3. Aichi Cancer Center)

[28P1-am2-035]Identification of daphnane diterpenoids from Daphne pseudo-mezereum by LC-MS analysis

○Kouharu Otsuki1, Midori Kato1, Takashi Kikuchi1, Wei Li1 (1. Faculty of Pharm., Sci. Toho Univ.)

[28P1-am2-036]Compounds with neuroprotective activity isolated from marine derived fungus

○miho hurukawa1, hitosi kamauti1, koichi takao1, yoshiaki sugita1 (1. Pharmacy and Pharmaceutical Sciences, Josai University )

[28P1-am2-037]Synthesis of kamebanin analogues and their cytotoxic activity

○Mio Watanabe1, Momoka Yagi1, Kei Ozawa2, Tomoyo Hasuda2, Yukio Hitotsuyanagi2, Koichi Takeya2, Reiko Yano1, Yutaka Aoyagi1, Ming-yu Gui3, Yong-Ri Jin3, Xu-Wen Li3 (1. Coll. of Pharm., Kinjo Gakuin Univ., 2. School of Pharm., Tokyo Univ. of Pharm. & Life Sci., 3. Depart. of Chem., JiLin Univ.)

[28P1-am2-038S]Synthesis of pisiferdiol analogues from Chamaecyparis pisifera and their cytotoxic activity PartⅤ

○Aika Higa1, Ryo Goshima1, Kyoka Nakashima1, Yukiko Kachi1, Miku Takasu1, Manami Toda1, Risa Obayashi1, Yutaka Aoyagi1, Reiko Yano1, Koji Yoshida1, Yoshimi Ichimaru3, Hyun-Sun Park4, Tomoyo hasuda2, Haruhiko Fukaya2, Yukio Hitotsuyanagi2 (1. Coll. Pharm, Kinjo Gakuin Univ., 2. School of Pharm. Tokyo Univ. of Pharm. & Life Sci., 3. Faculty of Pharm. Sci. Shonan Univ. of Med. Sci., 4. Faculty of Pharm. Osaka Ohtani Univ.)

[28P1-am2-039S]Identification of daphnane diterpenoids from Daphne tangutica by LC-MS analysis (part 2)

○Masayoshi Komaki1, Kouharu Otsuki1, Takashi Kikuchi1, Wei Li1 (1. Faculty of Pharm., Sci. Toho Univ.)

[28P1-am2-040S]Search for new natural products from Nocardia carnea IFM 12324 and biosynthetic gene analysis for an isolated compound

○Teruhisa Manome1, Ayaka Nakamura1, Yasumasa Hara1,2, Akiko Takaya1,2,3, Sayaka Ban3, Hiroki Takahashi2,3, Takashi Yaguchi3, Masami Ishibashi1,2 (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Plant Mol. Sci. Cent., Chiba Univ., 3. Med. Mycol. Res. Cent., Chiba Univ.)

[28P1-am2-041S]Studies on the antileishmanial constituents of medicinal plants (part 35) Chemical constituents of the Myanmar plant, PYINER LANKAR Sophora exigua

○Natsuki Matsuura1, Ayame Watanabe2, Ko Yasumoto3, Hiroyuki Fuchino4, Motoyoshi Satake5, Motoo Iida1, Osamu Shirota2, Kanami Yasumoto1,2 (1. TUS, Fac. Pharm. Sci., 2. Kagawa School of Pharm. Sci., Tokushima Bunri Univ., 3. Kitasato University, School of Marine Biosciences, 4. National Institutes of Biomedical Innovation, Health and Nutrition, 5. Showa Pharmaceutical University)

[28P1-am2-042]Studies on the antileishmanial constituents of medicinal plants (part 36) Chemical constituents of the Myanmar plant, Clerodendrum phlomides

○Junya Miyamoto1, Ko Yasumoto2, Motoo Iida1, Hiroyuki Fuchino3, Motoyoshi Satake4, Kanami Yasumoto1 (1. TUS,Fac,Pharm,Sci, 2. Kitasato University, School of Marine Biosciences, 3. National Institutes of Biomedical Innovation, Health and Nutrition, 4. Showa Pharmaceutical University)

[28P1-am2-043]Studies on the antileishmanial constituents of medicinal plants (part 37) Chemical constituents of the Myanmar plant, Se-pale Gentiana kuroo

○Yugo Yugami1, Ko Yasumoto2, Motoo Iida1, Hiroyuki Fuchino3, Motoyoshi Satake4, Kanami Yasumoto1 (1. TUS, Fac. Pharm. Sci., 2. Kitasato University, School of Marine Biosciences, 3. National Institutes of Biomedical Innovation, Health and Nutrition, 4. Showa Pharmaceutical University)

[28P1-am2-044]The structure analysis of secondary metabolites and investigation of culture conditions of Rhodotus palmatus

○Tatsuro Yoneyama1, Misaki Kakazu1, Masaaki Noji1 (1. Tokushima Bunri University)

[28P1-am2-045S]Studies on the constituents of Hypericaceous plants (55): Structures and biological activity of prenylated acylphloroglucinols from the flowers of Hypericum sp.

○Rena Takizawa1, Yusei Shimomoto2, Kiyoshi Imabayashi3, Daisuke Tsuji2,4, Kohji Itoh2, Yoshiki Kashiwada2, Naonobu Tanaka2 (1. Facul. Pharm. Sci., Tokushima Univ., 2. Grad. Sch. Pharm. Sci., Tokushima Univ., 3. Tech. Sprt. Dept., Tokushima Univ., 4. Facul. Pharm., Yasuda Women's Univ.)
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