archive_header_en_20251203154432269.png

20230323085903895_en.png

app_icon.png

Change account information such as the email address and password on the account setting screen common to Confit.

Login required to view

Password required to view

Presentation Information

Session Details

Enter the password to view the abstracts.<br><br>The password will be emailed to those who have completed the registration.

To browse or post comments, you must log in.

You cannot post comments as it is outside the comment posting period.

This comment has been deleted. You cannot reply to this comment.

Program Type

Sessions

Announcements

Profile management

Bookmark

Search presentations

Download PDF for print

Timetable

Stable and minimum-size solubilization of membrane proteins with cocktails of phospholipid analogs

Elucidation of the structures and functions of proteins is important not only for understanding biological phenomena but also for drug discovery research.  Essential technologies for protein research involve mass production of target proteins by recombinant expression or chemical synthesis and their site-specific chemical modification.  In addition, in the case of membrane proteins, their solubilization and stabilization are key techniques.  A method for incorporating in vitro-modified membrane proteins back into living cells would be a powerful approach for their in-cell analysis.  <br />    In this symposium, cutting-edge chemical methods for protein research will be presented and discussed, including the low-cost and efficient protein purification systems using oligosaccharides (by Kato), the peptide modification methods for the generation of artificial proteins (by Otaka), the chemical synthesis of difficult membrane proteins (by Hojo), the delivery of membrane proteins to cell membranes utilizing nanosiscs (by Ikeda), and the development of novel detergents enabling the facile structural and functional analysis of membrane proteins (by Matsuzaki).

The Pharmaceutical Society of Japan

The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)

The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)

[S11-1]Stable and minimum-size solubilization of membrane proteins with cocktails of phospholipid analogs

Password required to view