The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)
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Session Details

Oral Presentation(A) Pharmaceutical Chemistry

Drug design 2

Fri. Mar 29, 2024 2:15 PM - 3:15 PM JST
Fri. Mar 29, 2024 5:15 AM - 6:15 AM UTC
[Room 413] Conference Center 413 (4F)
Chair: Fujii Shinya, Satoshi Obika
2:15 PM - 2:27 PM JST(5:15 AM - 5:27 AM UTC)

[29-413-pm06S]Optimization of the 4'-thiomodification patterns on siRNA for effective anti-SARS-CoV-2 activities

○Yuhei Nogi1, Noriko Saito Tarashima1, Takaaki Koma2, Jun Tsukimoto1, Masako Nomaguchi2, Noriaki Minakawa1 (1. Graduate School of Pharmaceutical Science, Tokushima University, 2. Graduate School of Medicine, Tokushima University)
2:27 PM - 2:39 PM JST(5:27 AM - 5:39 AM UTC)

[29-413-pm07S]Preparation of a chemically modified mRNA using 4'-thio-NTP analogs

○Chihiro Kuroda1, Yuta Kashiwabara1, Jun Tsukimoto1, Noriko Saito Tarashima1, Noriaki Minakawa1 (1. Grad. Sch. Pharm. Sci., Tokushima Univ.)
2:39 PM - 2:51 PM JST(5:39 AM - 5:51 AM UTC)

[29-413-pm08S]3-Deazaguanosine showed anti SARS-CoV-2 activities via unexpected inhibition mechanism

○Keigo Yoshida1, Naoto Hinotani1, Moka Ogasa1, Noriko Saito Tarashima1, Takaaki Koma2, Masako Nomaguchi2, Noriaki Minakawa1 (1. Graduate School of Pharmaceutical Science, Tokushima University, 2. Graduate School of Medicine, Tokushima University)
2:51 PM - 3:03 PM JST(5:51 AM - 6:03 AM UTC)

[29-413-pm09S]Evaluation of RNAi activity of siRNA in Gryllus bimaculatus.

○Taketo Inoue1, Noriko Saito Tarashima1, Shintaro Inoue2, Sumihare Noji2, Taro Mito2, Noriaki Minakawa1 (1. Grad. School of Pharm. Sci., Tokushima Univ., 2. BIRC, Tokushima Univ.)
3:03 PM - 3:15 PM JST(6:03 AM - 6:15 AM UTC)

[29-413-pm10S]Inducing the photo-responsible aggregation of the antibody-oligonucleotide conjugate via G-quadruplex formation.

○Mizuki Oba1, Akiho Murai1, Noriko Saito Tarashima1, Jun Tsukimoto1, Noriaki Minakawa1 (1. Grad. Sch. Pharm. Sci., Tokushima Univ.)
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