The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)
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Session Details

Poster Presentation(B) Pharmaceutical Physics

Spectroscopic analysis 1/HPLC 1/LC-MS 1/Biological analysis

Fri. Mar 29, 2024 8:30 AM - 12:00 PM JST
Fri. Mar 29, 2024 11:30 PM - 3:00 AM UTC
[Poster 4] Exhibition Hall AB (1F)

[29P-am122]ICH-Q3D elemental impurity analysis of oral drugs by EDXRF

○Takami Nakao1, Tomoaki Sakamoto2, Takuji Shoda3, Keijiro Suzuki1, Eisaku Terashita1, Masahiro Ota1 (1. X-ray/Suface Business Unit, Analytical & Measuring Instruments Division, Shimadzu Corporation, 2. Division of Drugs, National Insuitute of Health Sciences, 3. Division of Organic Chemistry, National Insuitute of Health Sciences)

[29P-am123]Evaluation of each part of the p. quassioides via fluorescence fingerprint analysis

○Yasunori Hamazaki1,2, Satoko Shimbara-Matsubayashi1, Yuki Odanaka1, Nanami Fukui2, Takashi Yamazaki2, Masaru Kato1 (1. Grad. Sch. Pharm. Sci., Showa Univ., 2. OHTA'S ISAN Co., Ltd.)

[29P-am124]Development of a ratiometric fluorescence probe for evaluating the efficacy of boronic acid agents

○Shinya Takada, Fumiko Hara1, Shizuyo Horiyama1, Masayori Hagimori1 (1. Sch. Pharm., Mukogawa Women's Univ.)

[29P-am125]Chemical structure analysis of drugs and pharmaceutical materials using submicron-resolution infrared microscopy (O-PTIR)

○Naoki Baden1, Norio Urayama1 (1. Nihon Thermal Consulting)

[29P-am126]Potential of near-infrared spectral camera for PAT in flow synthesis

○Takuji Shoda1, Noriaki Fukamachi2, Yosuke Demizu1, Tomoaki Sakamoto1 (1. Natl. Inst. Health Sci., 2. KLV)

[29P-am127S]Characterization of rice wine using multivariate analysis and spectral analysis

○Sae Ueda1, Ryuichiro Suzuki1, Hiroaki Todo1, Yuji Higuchi2, Kenichi Akao2, Takashi Tanikawa1, Yutaka Inoue1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, 2. JASCO Corporation)

[29P-am128]Terahertz Time-Domain Attenuated Total Reflection Spectroscopy using Flow-Through Method for Continuous Monitoring of Neutralization Reaction

○Koichiro Akiyama1, Kazuki Horita1, Kazuhiro Takahashi1, Hiroshi Satozono1, Tomoaki Sakamoto2 (1. Hamamatsu Photonics K.K., 2. National Institute of Health Sciences)

[29P-am129]High-speed measurement of tablet content using high-power time-stretch near-infrared spectroscopy

○Koji Nakayama1, Aya Ikarashi2, Takuma Yokoyama2, Tomoaki Sakamoto3 (1. TOWA PHARMACEUTICAL CO.,LTD., 2. USHIO INC., 3. National Institute of Health Science, MHLW)

[29P-am130S]Construction of Heterospin MRI Contrast Agents with Detection Ability of Lipid-radical

○Akane Yokomizo1, Shota Matsumoto1, Kazuteru Usui1, Ken-ichi Yamada2, Satoru Karasawa1 (1. Showa Pharmaceutical Univ., 2. Grad. Sch. Pharm. Sci., Kyushu Univ.)

[29P-am131S]Emission Properties and Organelle-imaging of Push-pull Type Bicyclic Fluorescent Probes

○Ryoma Kato1, Shota Matsumoto1, Tomohiro Umeno1, Kazuteru Usui1, Satoru Karasawa1 (1. Showa Pharmaceutical Univ.)

[29P-am132]Investigation of retention and molecular recognition abilities of molecularly imprinted polymers for bisphenol A and its derivatives

○Chie Honda1, Kanae Nishimura2, Noboru Hayama3, Jun Haginaka1 (1. Inst. Biosci., Mukogawa Women's Univ., 2. Sch. Pharm. Pharmaceut. Sci., Mukogawa Women's Univ., 3. Fac. Pharm., Osaka Med. Pharm. Univ.)

[29P-am133S]Development of quality assurance method for lipid nanoparticles by HPLC

○Yuki Nakatani1, Daisuke Funatsu1, Tomoka Morita1, Eiichi Yamamoto2, Nozomi Murayama3, Shota Miyazaki3, Masaru Kato4 (1. Sch. Pharm., Showa Univ., 2. National Institute of Health Sciences, 3. GL Sciences Inc., 4. Grad. Sch. Pharm. Sci., Showa Univ.)

[29P-am134]HILIC separation of N-linked glycans and glycopeptides by polyethylene imine-functionalized silica gel

○Norihito Maru1, Hiroki Imamura1, Shohei Kosaka1, Makoto Kawai1, Takahiro Miyauchi2 (1. Fuji Silysia Chemical, 2. Daiichi Sankyo RD Novare)

[29P-am135]Comparison of separation behavior using phenyl group columns

○Tomoyasu Tsukamoto1, Ryuji Koyama1, Norikazu Nagae1 (1. Chromanik Technologies Inc.)

[29P-am136S]Expansion of analysis targets and investigation of separation and retention of new columns in precision quantitative determination for DKD progression prediction marker candidate.

○Itsumi Konno1, Ryota Kujirai2, Mizuki Abe1, Yotaro Matsumoto2, Takaaki Abe3,4, Yoshihisa Tomioka2 (1. Facu. Pharm. Sci., Tohoku Univ., 2. Grad. Sch. Pharm. Sci., Tohoku Univ., 3. Nephrology and Hypertension, Tohoku Univ. Hosp., 4. Grad. Sch. Biomed. Engin., Tohoku Univ.)

[29P-am137]Development of phosphobetaine-type polymer selector and its application

○Tomotaka Mizuguchi1, Kengo Murata1, Hideki Motoda1, Kanji Nagai1, Takafumi Onishi1, Atsushi Ohnishi1 (1. DAICEL CORPORATION)

[29P-am138]Determination of intracellular dopamine by HPLC-FLD with post-column derivatization using the König reaction

○Ryu Mochizuki1, Yasumitsu Ogra1 (1. Grad. Sch. Pharm. Sci., Chiba Univ.)

[29P-am139]Development of A Green Analytical Method for Determination of Anticancer Ingredients in Daily Intake

○Yi-Wen Huang1, Chia-Hsien Feng*2 (1. Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Taiwan, 2. Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Taiwan)

[29P-am140]Determination of the neuroprotective dipeptides and amino acids in biological samples by microwave-assisted derivatization coupled with HPLC-UV

○Yi-Rou Wang1, Chia-Hsien Feng*1 (1. Department of Fragrance and Cosmetic Science, Collage of Pharmacy, Kaohsiung Medical University, Taiwan)

[29P-am141S]Development of stable isotope oxygen short-chain fatty acids: application of derivatized LC-MS/MS for quantitative analysis of short-chain fatty acids in saliva samples

○Aoi Ichikawa1, Takahiro Takayama1, Shumpei Fujie2, Motoyuki Iemitsu2, Koichi Inoue1 (1. Pharm. Sci., Ritsumeikan Univ., 2. Sport and Health Sci., Ritsumeikan Univ.)

[29P-am142]Utilization and effects of software for supporting the development of HPLC analytical methods

○Tomoya Ohmura1, Shinya Ogata1, Hiroshi Sakamaki1 (1. Chemicals Evaluation and Research Institute, Japan)

[29P-am143]Repeatability assessment of an HPLC method for soft capsules analysis by the FUMI theory

○Ai Sano1, Masato Takahashi1, Akira Kotani2, Hideki Hakamata2 (1. TOYO CAPSULE, 2. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)

[29P-am144]Evaluation of extracellular vesicle preparations using high performance liquid chromatography with multi-angle light scattering measurement.

○Hirotaka Nishimura1, Noritaka Hashii1, Tomofumi Yamamoto1, Akiko Ishii-Watabe1 (1. National Institute of Health Sciences)

[29P-am145]Optimization of ion-exchange chromatography for characterization of therapeutic monoclonal antibodies

○Akira Harazono1, Hiroko Shibata1, Akiko Watabe Ishii1 (1. National Institute of Health Sciences)

[29P-am146S]Investigation of sample preparation methods to expand libraries for quantitative phosphoproteome analysis

○Masato Shimoi1, Maiko Inoue1, Hajime Mizuno1, Susumu Y. Imanishi1 (1. Fac. Pharm., Meijo Univ.)

[29P-am147S]Application of the phosphorylation site-specific SWATH data analysis method SimSkyline to comprehensive analysis of proteins

○Waka Saito1, Reika Ozeki1, Toru Hasegawa1, Hajime Mizuno1, Susumu Y. Imanishi1 (1. Fac.Pharm.,Meijo Univ.)

[29P-am148S]Quantitative proteomic analysis of plasma from schizophrenia patients treated with clozapine

○Rira Sato1, Kana Watanabe1, Moeka Kondo1, Akira Yoshimi1,2, Kiyoshi Fujita3, Norio Ozaki2, Yukihiro Noda1,2, Hajime Mizuno1, Susumu Y Imanishi1 (1. Fac. Pharm., Meijo Univ., 2. Grad. Sch. Med., Nagoya Univ., 3. Okehazama Hosp.)

[29P-am149S]Derivatization procedure to generate product ion containing estradiol-skeleton for reliable determination of its serum/plasma concentrations by LC/ESI-MS/MS

○Hiroki Matsuoka1, Honoka Kaneko2, Hironori Kobayashi3, Takayuki Ishige4, Tatsuya Higashi1 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 3. Clinical Laboratory Division, Shimane University Hospital, 4. Division of Laboratory Medicine, Chiba University Hospital)

[29P-am150S]Determination of conjugation position of 23,25-dihydroxyvitamin
D3-glucuronide in human urine by derivatization-assisted LC/ESI-MS/MS using a new Cookson-type reagent

○Natsuki Yoshida1, Kazunari Takada2, Ogawa Shoujiro3, Higashi Tatsuya1 (1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2. Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 3. Faculty of Pharmaceutical Sciences, Fukuyama University)

[29P-am151S]Analysis of nucleic acid adducts derived from acetaldehyde in DNA and RNA of cells

○Rei Hamamoto1, Soo Takasu1, Yukihiro Esaka1,2 (1. Gifu Pharm. Univ., 2. United Grad. Sch. of Drug Discovery and Medical Information Sci. , Gifu Univ.)

[29P-am152S]Lipid Metabolome Analysis Using SFC/MS to Elucidate the Mechanism of Bortezomib Resistance in Multiple Myeloma

○Mami Akao1, Chisato Takahashi1, Muneshige Tokugawa1, Masaki Ri2, Shinsuke Iida2, Keiko Maekawa1 (1. Doshisha Women's College of Liberal Arts, 2. Grad. Sch. Medical Sci., NAGOYA CITY Univ.)

[29P-am153S]Exploration of substrates and metabolites of orphan cytochrome P450 CYP2U1 expressed in E. coli.

○Mana Nakazawa1, Muneshige Tokugawa1, Chisato Takahashi1, Keiko Maekawa1 (1. Doshisha Women's College of Liberal Arts)

[29P-am154]Measurement of transport activities of iso-allo-bile acids in bile salt export pump and multidrug resistance-associated proteins using LC-MS/MS

○Tsuyoshi Murai1, Sato Kousuke1, Takahiro Sasaki1 (1. Sch. Pharm. Sci., Health Sci. Univ. Hokkaido)

[29P-am155S]Development of an analytical method for sphingoglycolipids and oligosaccharides for the searching of biomarkers for renal cell carcinoma

Chika Kanno1, ○Natsuki Sano1, Masamitsu Maekawa1,2,3, Izumi Sakamoto3, Yosihide Kawasaki3, Akihiro Ito3, Nariyasu Mano1,2,3 (1. Fac. of Pharm. Sci., Tohoku Univ., 2. Dept. Pharm. Sci., Tohoku Univ. Hosp., 3. Grad. Sch. Med., Tohoku Univ.)

[29P-am156]Measurement of luteolin and apigenin in herbal tea and Chinese herbal tea by IT-SPME/LC-MS/MS method

○Atsushi Ishizaki1, Yurika Hara1, Hiroyuki Kataoka1 (1. School of Pharmacy, Shujitsu University)

[29P-am157]Evaluation of photoreactive DNA aptamers for analytical applications

○Yutaka SADAKANE1, Akari Tsubokura1, Mitsuki Kasai1, Yuka Ito1, Chihiro Ito1, Shota Morimoto1 (1. Suzuka Univ. Med. Sci.)

[29P-am158]Construction of EGFP-labeled rat scFv library for selection using FACS

○Yoshinori Kato1,2, Yuni Ichikawa1, Yui Kataoka1, Takuya Hirao1, Takeshi Ito1, Chihiro Tetsuka1, Harumi Yamada1,2 (1. Sch. Pharm., IUHW, 2. Grad. Sch. Pharm. Sci., IUHW)

[29P-am159]5-Substituted D-kynurenine derivatives as fluorometric assay probes for D-amino acid oxidase activity and their application in eels.

○Tatsuya Sakamoto1, Hiroshi Sugasawa1, Mayu Onozato1, Takeshi Fukushima1 (1. Pharm. Sci., Toho Univ.)

[29P-am160S]Development of efficient purification method for urinary cfDNA

○Ryo Fukushima1, Ibuki Nakano1, Yuina Ogura1, Katou Masaru2 (1. Sch. Pharm., Showa Univ., 2. Grad. Sch. Pharm. Sci., Showa Univ.)

[29P-am161]Serum methylglyoxal and D,L-lactate as a potential influencing factor in Taiwanese patients with multiple sclerosis

○Hsi-Chih Huang1, Pei-Yun Tsai1, Yu-Ning Chang1, Jen-Ai Lee*1 (1. Pharm. Taipei Medical Univ.)

[29P-am162]Urine Metabolomics in Patients with Multiple Sclerosis in Taiwan

○Yu-Ning Chang1, Pei-Yun Tsai1, Hsi-Chih Huang1, Shwu-Huey Wang2, Jen-Ai Lee*1 (1. Pharm. Taipei Medical Univ. , 2. The Core Facility Center. Taipei Medical Univ.)
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