The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)
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Session Details

Poster Presentation(A) Pharmaceutical Chemistry

Synthetic compounds in drug discovery/Natural medicines and biological products/Middle-molecule drugs

Fri. Mar 29, 2024 1:30 PM - 5:00 PM JST
Fri. Mar 29, 2024 4:30 AM - 8:00 AM UTC
[Poster 3] Exhibition Hall AB (1F)

[29P-pm094S]Application of Graft-type polymer with immobilized catalyst using microwave to flow reaction

Yoshinori Okuno1, ○Arisa Sera1, Ayu Kobayashi1, Shunsuke Tenma1, Takuya Iwamura1, Yasuyo Mitsutaki1, Kento Sekizuka1, Nami Kawasaki1, Ran Higashisanjo1, Toshiyasu Nakakita1, Syoji Aoki2, Shigeki Isomura1, Yasuo Sato1 (1. Yokohama University of Pharmacy, 2. ECE Co., Ltd.)

[29P-pm095]Identification of 2-(difluoroanilino)-chromen-4-one analogues with tumoricidal effects on multidrug-resistant cancers

○YI-Han Chang1,2, I-Ting Wu3, Chin-Chuan Hung3, Hsin-Yi Hung2 (1. Institute of Chemistry, Academia Sinica, Taipei, Taiwan, 2. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan , 3. Department of Pharmacy, College of Pharmacy, China Medical University, Taichung, Taiwan)

[29P-pm096]Eperisone analogues as a rescuer of mistranslation by CDKAL1 defect; synthesis and antihyperglycemic effect.

Manabu Tejima1, Tomoko Hashimoto1, Mana Nakagawa1, Tomoyuki Hoshina1, Osamu Ohno1, Kotaro Takasaki2, Shintaro Taniguchi2, Kanako Nakamura2, Ayano Goto2, Chiaki Yonebara2, Fan-Yan Wei3, Kazuhito Tomizawa4, ○Kenji Matsuno5 (1. Sch. Adv. Engin., Kogakuin Univ., 2. Fac. Pharm. Sci., Teikyo Heisei Univ., 3. Grad. Sch. Life Sci., Tohoku Univ., 4. Fac. Life Sci., Kumamoto Univ., 5. Fac. Pharmacy, Yasuda Women's Univ.)

[29P-pm097]Characterization of direct target proteins in the cytoplasm of ST32da, an ATF3-induced single compound

○Nain Chu Gao1, Wei-Jan Huang1, Heng Lin2 (1. Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan, 2. Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan)

[29P-pm098]Drug discovery research of naphthoquinone derivatives for the treatment of Onychomycosis

○Yoshihiko Noguchi1,2, Naoaki Arima3, Kazunari Sakai3, Kazutoyo Abe3, Ken Sasaki2, Tadaaki Ohgiya3, Tomoyasu Hirose1,2, Toshiaki Sunazuka1,2, Hideaki Hanaki1,2 (1. Grad. Sch. Infect. Ctl. Sci., Kitasato Univ., 2. Ōmura Satoshi Memorial Insti., Kitasato Univ., 3. Kowa company, LTD.)

[29P-pm099]Indole-2-carboxamide derivatives with enhanced antibacterial activity against nontuberculous mycobacteria and improved water solubility

○Atsushi Seki1, Isao Momose1, Chigusa Hayashi1, Masayuki Igarashi1, Masakatsu Shibasaki1 (1. Inst. of Microb. Chem.)

[29P-pm100]Development and application of "VED" to heal itching caused by atopic dermatitis, pain, scars, cramps, skin spots, acne scars, muscle pain, etc.

○Masanori Somei1, Hiizu Somei1, Kazuko Somei1 (1. SOMEIYAKKO Kenkyusho)

[29P-pm101]The omega-9 monounsaturated fatty acid in Sapindus mukorossi seed prevent periodontitis in animal model with ligature-induced periodontitis

○Haw-Ming Huang1, Shih-Kai Lin1, Li-Fu Chen1 (1. Sch. Dent., Taipei Med. Univ. Taipei, Taiwan)

[29P-pm102S]Synthetic Study of JBIR-155, a Specific Class D β-lactamase Inhibitor

○Yoshiki Yoshida1, Takehiro Nishimura1, Haruhisa Kikuchi1 (1. Fac. Pharm., Keio Univ.)

[29P-pm103]The treatment efficiency of Sapindus mukorossi seed hydrosol on the periodontitis: A microbiome analysis

○Li-Fu Chen1, Xiang-Wei Chen1, Shih-Kai Lin1, Haw-Ming Huang1 (1. Sch. Dent., Taipei Med. Univ. Taipei, Taiwan)

[29P-pm104]Anti-bacterial, anti-inflammatory and skin regeneration effects of Sapindus mukorossi seed water extract

○Hsuan-Yu Lai1, Haw-Ming Huang1 (1. Sch. Dent., Taipei Med. Univ.)

[29P-pm105S]Dissolution of cannabidiol in hydrated ionic liquids for skin permeation application

○Mineto Koyanagi1, Ruriko Kawanabe2, Ayumu Yoshizaki2, Kyoko Fujita1 (1. School of Pharmacy Tokyo University of Pharmacy and Life Sciences, 2. Graduate School of Medicine and Faculty of Medicine, The University of Tokyo)

[29P-pm106S]Analysis of the interaction between DNA aptamers and target molecules in hydrated ionic liquids

○Hidenori Tsukuhiji1, Shintaro Inaba2, Takuya Honda2, Kaori Tsukakoshi2, Hiroyuki Ohno2, Kazunori Ikebukuro2, Kyoko Fujita1 (1. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 2. Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology)

[29P-pm107]Effects by N-substituted N-demethylsinomenine on inhibitory effects against acute nociceptive response induced by formalin on mice

○Hiroki Kataoka1, Soh Katsuyama1, Yukino Ogasawara1, Naoko Okada1, Toshiaki Saitoh1, Fumihide Takano1, Chikai Sakurada1 (1. Nihon Pharm. Univ.)

[29P-pm108S]Synthesis of antitrypanosomal compounds based on lignan lactone skeletons

○Yuka Tani1, Takehiro Nishimura1, Haruhisa Kikuchi1 (1. Fac. Pharm., Keio Univ.)

[29P-pm109]Structural design of negative pressure-driven pharmaceutical nebulizer: A computational fluid dynamics analysis

○Hung-Chieh Wu1, Haw-Ming Huang1 (1. Sch. Dent., Taipei Med. Univ.)

[29P-pm110]CFD Study of the Effect of the Angle Pattern on Iliac Vein Compression Syndrome

○Hsuam Wei Chen1, Haw-Ming Huang2 (1. Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical Univ., 2. School of Dentistry, Taipei Medical University, Taiwan)

[29P-pm111]Development of the bicyclic mid-size peptide KS-133 as a VIPR2-specific antagonist and its antitumor effect through modulation of macrophage polarity

○Kotaro Sakamoto1, Eijiro Miyako2, Shinsaku Nakagawa3, Yukio Ago4, Akira Nishiyama5 (1. Ichimaru Pharcos co. Ltd., 2. JAIST, 3. Osaka Univ., 4. Hiroshima Univ., 5. Kagawa Univ.)

[29P-pm112]Purity Confirmation of Synthetic Peptides - Amino Acid Analyses -

○Tomoko Kuriki1, Ayano Tanabe1, Hidetoshi Terada1 (1. SHIMADZU CORPORATION)

[29P-pm113]Amino acid sequence analysis of synthetic peptides using protein sequencer

○Miho Akagi1, Ryo Nagano1, Ayaka Hori1, Kumiko Yamaguchi1, Tomoko Kuriki1, Hidetoshi Terada1 (1. SHIMADZU CORPORATION)

[29P-pm114]Determination for the Molecular Weight of Synthetic Peptides by single quadrupole mass spectrometer

○Miho Kawashima1, Tomoko Kuriki1 (1. Shimadzu Corporation)

[29P-pm115]Streamlining of Synthetic Peptides Purification Using Analytical-Preparative Switching LC-MS System

○Yusuke Masuda1, Yuki Suzuki1, Tomoko Kuriki1, Ryo Kubota1, Hidetoshi Terada1 (1. Shimadzu Corporation)

[29P-pm116]Purity Confirmation of Synthetic Peptides - Determination of Counter Ions -

○Ayano Tanabe1, Tomoko Kuriki1, Hidetoshi Terada1 (1. Shimadzu Corporation)

[29P-pm117S]Synthesis of middle-molecules from abietic acid using a natural product reconstruction strategy

○Fumiaki Kobayashi1, Takehiro Nishimura1, Haruhisa Kikuchi1 (1. Fac. Pharm., Keio Univ.)

[29P-pm118]Construction of HUVEC and HL-60 cell adhesion activity assay and inhibitory effect of SLeX-related product

○Susumu Kawano1, Kaisei Motoyama1, Yuka Shirahama1, Eito Okamoto1, Hiroaki Kaji1 (1. Shujitsu University School of Pharmacy)

[29P-pm119S]Identification of specific substrate peptides for the detection of MMP-12 activity

○Ryuta Maruoka1, Sota Yamada1,2, Eita Sasaki1,2, Kotaro Matsumoto3, Masaru Takeshita3, Kenjiro Hanaoka1,2 (1. Fac. Pharm., Keio Univ, 2. Grad. Sch. Pharm. Sci., Keio Univ., 3. Fac. Med.,Keio Univ)

[29P-pm120S]Study on the synthesis of heterobivalent compounds composed of oxytocin and endomorphin-1 aimed for a novel bitopic ligand for mu-opioid receptor

○Takeru Chiba1, Takaaki Mizuguchi1, Hideaki Fujii1 (1. Kitasato University, School of Pharmacy)
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