The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)
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Session Details

Poster Presentation(B) Pharmaceutical Physics

Functional polymers/Adsorption, interfacial phenomena/Intermolecular interaction/Physical properties of pharmaceuticals /Structural biology

Fri. Mar 29, 2024 1:30 PM - 5:00 PM JST
Fri. Mar 29, 2024 4:30 AM - 8:00 AM UTC
[Poster 4] Exhibition Hall AB (1F)

[29P-pm121S]Effects of chitosan/HPMC gel structure on physical properties of film for oral mucositis treatment

○Sayumi Yamauchi1, Nanae Kabaya1, Takeshi Oshizaka1, Kenji Mori1, Issei Takeuchi1, Kenji Sugibayashi1,2 (1. Faculty of Pharm. Sci., Josai International Univ, 2. Faculty of Pharm. Sci., Josai Univ)

[29P-pm122]Synthesis and in vitro evaluation of photosensitizer-MRI contrast agent-conjugated dextran for improving therapeutic efficacy of PDT

○Yuhei Ohta1, Teruki Kohara1, Ryota Abe1, Shoko Okazaki1, Keizo Takeshita1 (1. Fac. of Pharm. Sci., Sojo Univ.)

[29P-pm123S]Development of biodegradable culture sheet using surface modification of side-chain crystalline block co-polymer

○Kokoro Yabumoto1, Mai Hazekawa1, Daisuke Watase1, Takuya Nishinakagawa1, Masato Hosokawa1, Daisuke Ishibashi1 (1. Fac.Pharm., Fukuoka Univ.)

[29P-pm124]Adsorption characteristics of volatile small molecules on solid state cyclodextrins

○Taizen Den1, Hiroyuki Fujimori1, Jin Hisazumi1, Susumu Hasegawa1, Makoto Miyajima1 (1. Daiichi Sankyo Co., Ltd.)

[29P-pm125]Shape effects of nanomaterials and interaction forces in protein corona formation - Using chemical modifications of the target protein -

○Aren YAMAMOTO1, Kunisato KUROI1, Fumihiko Fujii1 (1. Fac.Pharm. Sci., KobeGakuin Univ.)

[29P-pm126]Shape effects of nanomaterials and interaction forces in protein corona formation - Using fluorescence correlation spectroscopy -

○Shunpei Okumoto1, Kunisato Kuroi1, Fumihiko Fujii1 (1. Fac. Pharm. Sci., Kobe Gakuin Univ.)

[29P-pm127S]Creation and stabilization of emulsion-like particles produced by liquid-liquid phase-separated peptides

○Ibuki Yamashita1, Keisuke Ikeda1, Hiroyuki Nakao1, Minoru Nakano1 (1. Toyama Univ)

[29P-pm128]Shape effects of nanomaterials and interaction forces in protein corona formation - Using fluorescence quenching experiments -

○Naoaki Ban1, Kunisato Kuroi1, Fumihiko Fujii1 (1. Fac. Pharm. Sci., Kobegakuin Univ.)

[29P-pm129]Examination of surface-ligand densities at the sides and bottoms of rod-shaped nanomaterials

○Yuki Tominaga1, Kunisato Kuroi1, Fumihiko Fujii1 (1. Fac.Pharm.Sci.,Kobegakuin Univ.)

[29P-pm130]Dispersion stability of iron oxide nanoparticles in the condensation reaction in aqueous solutions of zwitterionic compounds

○Takahiro Sasaki1, Wakana Sakagami1, Honami Ban1, Yume Honma1, Miho Hashimoto1, Kousuke Sato1, Tsuyoshi Murai1 (1. Sch. Pharm. Sci., Health Sci. Univ. Hokkaido)

[29P-pm131]Determination of surface-ligand densities of nanomaterials by FTIR spectroscopy

○Shintaro Ito1, Kunisato Kuroi1, Fumihiko Fujii1 (1. Fac. Pharm. Sci., Kobegakuin Univ.)

[29P-pm132]Kinetic analysis of promotion mechanism of insulin amyloid formation through adsorption of insulin onto hydrophilic polyvinylidene fluoride membrane

○Tomohiro Tsuchida1, Shingo Tsurumoto1, Kanji Hasegawa1, Yuta Okumura1, Kengo Mitsuya1, Satoru Goto1 (1. Tokyo University of Science)

[29P-pm133]Development of a method for measuring erythropoietin in plasma by biolayer interferometry

○Yoshihiro Mihara1, Masahiro Nishimura1,2, Seiichiro Kano3 (1. Dept. Med. Chem. Pharm. Sci., Hokkaido University of Science., 2. Kutchan-Kosei General Hospital, 3. Dept. Life Sci. Pharm. Sci., Hokkaido University of Science.)

[29P-pm134S]Binding affinity of Low Density Lipoprotein and Proteoglycans based on morphological observation

○Aoi Saito1, Hiroyuki Ebina1, Takahisa Hiruma1, Seiji Takeda1, Yoshihiro Mihara1 (1. Faculty of Pharm. Sci.,Hokkaido University of Science)

[29P-pm135S]Preparation of scFv antibody for reducing side effect

○Chisato Ishida1, Takashi Tadokoro1, Reo Omura2, Asami Tomita2, Aoi Sugiyama1, Kazuhide Miyamoto1, Katsumi Maenaka2 (1. Fac. Pharm. Sci., Sanyo-Onoda City Univ., 2. Grad. Sch. Pharm. Sci., Hokkaido Univ.)

[29P-pm136S]Binding properties of E/Z-Doxepin isomers to histamine H1 receptor

○Hiroto Kaneko1, Ryunosuke Korenaga1, Satoru Nagatoishi2,3, Kouhei Tsumoto2,3, Tadashi Ando4, Mitsunori Shiroishi1 (1. Dept.of Biol.Sci. and Technol., Tokyo Univ.of Sci., 2. Dept. of Bioeng., Sch.of Eng, Univ.of Tokyo, 3. Inst. of Med.Sci., Univ.of Tokyo, 4. Dept.of Appl. Electronics., Tokyo Univ.of Sci.)

[29P-pm137]Intermolecular interaction analysis of ibuprofen and xanthine derivative mixtures by applying singular value decomposition for IR spectra

○Hikaru Kataoka1, Kanji Hasegawa1, Tomohiro Tsuchida1, Satoru Goto1 (1. Grad. Sch. Pharm., Tokyo Univ. Sci.)

[29P-pm138]Improvement of multi-analyte solubility/solution stability evaluation system in drug discovery research

○Shingo Asano1, Kazuyuki Tokumaru1, Shinnosuke Hayashi1, Motohiro Shiraki1 (1. Pharmaceutical Research Laboratories, Toray Industries, Inc.)

[29P-pm139]Dissolution profiles of oral disintegrating tablet with taste masking granule polymer coating in biorelevant bicarbonate buffer

○Masaki Higashino1,2, Kiyohiko Sugano1 (1. Molecular Pharmaceutics Lab., College of Pharmaceutical Sciences, Ritsumeikan University, 2. Research & Development Division, Towa Pharmaceutical Co., Ltd)

[29P-pm140]Antioxidation, anti-melanin production and improvement of water solubility of Scutellaria baicalensis co-extracted with cyclodextrin

○Shih-Han Pan1, Tzu-Ching Lin2, Feng-Lin Yen1 (1. Department of fragrance and cosmetic science, College of Pharmacy, Kaohsiung medical university, Kaohsiung City, Taiwan, 2. Department of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan)

[29P-pm141]Ursolic acid nanofibers increase the anti-breast cancer activity by enhancing water solubility and skin absorption

○Hsuan Fu1, Feng-Lin Yen2, Tzu-Hui Wu3, Chih-Peng Ma4 (1. Doctorol Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan., 2. Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan., 3. School of Pharmacy, College of Pharmacy, Tajen University, Pingtung, Taiwan., 4. Department of Radiology, Pingtung Christian Hospital, Pingtung, Taiwan.)

[29P-pm142]Enhanced Water Solubility, Antioxidant And Photoprotective Activity Of Kaempferol Nanostructured Lipid Carriers

○Cheng Yu Liu1, Tzu Ching Lin2, Feng Lin Yen1 (1. Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan, 2. Department of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan)

[29P-pm143]Preparation, solubility, in vitro absorption and anti-inflammation of taxifolin nanoparticle delivery system

○CHIA-YI CHAN1, CHUN-YIN YANG2, FENG-LIN YEN1 (1. Department of Fragrance and Cosmetic Science, Kaohsiung Medical University, Kaohsiung City, Taiwan, 2. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung City, Taiwan.)

[29P-pm144]Basic study on designing cyclodextrin-containing formulations for drug delivery to the brain

○Noriko Ogawa1, Miyuu Kida1, Masaru Nishimura1, Toshiya Yasunaga1, Hiromitsu Yamamoto1 (1. Aichi Gakuin Univ.)

[29P-pm145S]Exploring and characterizing co-crystals of Lisinopril as Active Pharmaceutical Ingredients

○Yuma Aoki1, Ryotaro Haku1, Haruka Uchida1, Toshiro Fukami1 (1. Meiji Pharmaceutical University)

[29P-pm146]Evaluation of log P of endocrine disruptors using vibrational frequency calculation by the DFT method

○Masao Fujisawa1, Tomonori Ohata2, Hiroyuki Tsutsumi2, Hirohito Ikeda2 (1. Dept. of Biotechnological Science, Kindai Univ., 2. Fac. of Pharmaceutical Science, Fukuoka Univ.)

[29P-pm147S]Preparation, characterization of solid-dispersions of Lidocaine with Sulfosalicylic acid

○Manami Nomura1, Mitsuaki Suzuki2, Junki Tomita3, Takashi Tanikawa1, Yutaka Inoue1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, 2. Faculty of Science, Josai University, 3. Instrumental Analysis Center, Josai University)

[29P-pm148S]NMR spectroscopic characterization of the active residue of hOGG1

○Riki Nakatsuka1, Masayuki Morikawa1, Kouta Shigematsu1, Takuya Okada1, Naoya Ichihara1, Kiriko Zaha1, Yoshikazu Hattori1,2, Yoshiyuki Tanaka1 (1. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 2. Institute of Advanced Medical Sciences, Tokushima University)

[29P-pm149]Mechanistic analysis of glycosylase reaction with a novel hOGG1 active mutant

○masayuki morikawa1, yoshikazu hattori1,2, ryuto tominaga1, mizuki fujimoto1, kouta sakano1, mariko fukuta1, kota shigematsu 1, takuya okada1, naoya ichihara1, riki nakatsuka1, haruka mano1, saki komuro3, masaki unno3,4, yoshiyuki tanaka 1 (1. Faculty of Pharmeceutical Sciences, Tokushima Bunri University, 2. Institute of Advanced Medical Sciences, Tokushima University, 3. Institute of Quantum Beam Science, Graduate School of Science and Engineering, Ibaraki University, 4. Frontier Research Center for Applied Atomic Sciences, Ibaraki University)

[29P-pm150]Relationship between protonation states of the active site and the broad substrate recognition of human oxidized nucleotide hydrolase

Yukari Koga-Ogawa1, Kana Fujimiya2, Mami Chirifu3, Masataka Goto2, Shinji Ikemizu3, Yusaku Nakabeppu4, Yuriko Yamagata3,5, ○Teruya Nakamura3 (1. Fac. Health Sci., Nihon Institute of Medical Science, 2. Sch. Pharm., Kumamoto Univ., 3. Grad. Sch. Pharm. Sci., Kumamoto Univ., 4. Med. Inst. Bioreg., Kyushu Univ., 5. Shokei Univ.)

[29P-pm151S]X-ray crystal structure analysis of human monomeric carbonyl reductase complexed with a flavonoid compound

○Sana Takada1, Yuka Jimbo1, Yasumitsu Sakamoto2, Takeshi Miura3, Satoshi Endo4, Nobutada Tanaka1 (1. Sch. Pharm. Kitasato Univ., 2. Sch. Pharm. Iwate Medical Univ., 3. Sch. Pharm. Mukogawa Women's Univ., 4. Gifu Pharm. Univ.)

[29P-pm152S]Structural analysis of Damage Suppressor from Ramazzottius varieornatus

○Rio Yasuta1, Kohei Abe1, Tsubasa Takemori1, Takahiro Yamauchi2,3, Yasuhito Iizuka1,2, Masaru Tsunoda1,2 (1. Fac. Pharm., Iryo Sosei Univ., 2. Grad. Sch. Life Sch. Technol., 3. Fukushima Rosai Hosp.)

[29P-pm153]Biological materials that promote redox reactions between monoamine neurotransmitters and copper

○Takumi Kurihara1, Ai Hamada1, Nozomi Mitomo1, Saki Kuroda1, Takashi Miura1 (1. Dept.Pharm.Sci.,Int.Univ.Health and Welfare)

[29P-pm154]Search for crystallization conditions for structural analysis of the siderophore biosynthetic enzyme PvsA from Vibrio parahaemolyticus.

○Koji Tomoo1, Keiko Tomita1, In Yasuko1, Katsushiro Miyamoto1, Takahiro Tsuchiya1, Katsuhiko Minoura1, Tomotaka Tanabe2, Tatsuya Funahashi2 (1. Osaka Medical and Pharmaceutical University, 2. Matsuyama University)

[29P-pm155]Search for crystallization conditions for structural analysis of the periplasmic ferric binding protein FbpA from Vibrio vulnificus.

○Tomoki Ebisutani1, Yasuko In1, Katsushiro Miyamoto1, Takahiro Tsuchiya1, Katsuhiko Minoura1, Tomotaka Tanabe2, Tatsuya Funahashi2, Koji Tomoo1 (1. Osaka Medical and Pharmaceutical University, 2. Matsuyama University)

[29P-pm156]The nuclear transport mechanism of PPARg revealed by the Cryo-EM structure

○Sachiko Toma-Fukai1,2, Yutaro Nakamura2, Akihiro Kawamoto3, Toshiaki Teratani4, Hikaru Shimizu2, Mika Hirose3, Koki Hayama1, Ruri Kojima5, Kanami Yoshimura5, Masaki Ishii6, Shinya Ohata6, Kenji Iwasaki3, Takayuki Kato3, Hironari Kamikubo1, Toshimasa Itoh7, Kengo Tomita8, Toshiyuki Shimizu2 (1. Grad. Sch. Sci. and Tech., NAIST, 2. Grad. Sch. Pharm. Sci., The Univ. of Tokyo, 3. IPR, OSAKA univ., 4. Sch. Med., Keio Univ., 5. Fac. Pharm. Musashino Univ., 6. Res. Inst. Pharm. Sci., Musashino Univ., 7. Showa. Pharm. Univ., 8. NDMC)

[29P-pm157S]Structural and functional effects of Charcot-Marie-Tooth disease-related amino acid substitutions on myelin protein zero

○Kotaro Okamura1, Mina Nakayama1, Emika Neriki1, Kazuhiro Mio2,4, Mikio Tanabe3, Masayoshi Sakakura1,4 (1. Sch. of Sci., Yokohama City Univ., 2. AIST-UTokyo operando OIL, 3. KEK, IMSS, SBRC, 4. Grad. Sch. Med. Life Sci., Yokohama City Univ.)

[29P-pm158S]Development of liquid sample observation method for pulse electron microscope

○Ryoya Katayama1, Takeru Yamasaki1, Tomoharu Matsumoto1, Akihiro Narita1 (1. Grad. Sch. Sci., Nagoya Univ.)

[29P-pm159S]Molecular mechanism of ligand A2L recognition by immune activation receptor LILRA2

○Jiaqi Wang1, Atsushi Furukawa1,2, Kouyuki Hirayasu3,4, Rika Yamazaki1, Hisashi Arase3, Katsumi Maenaka1,5 (1. Pharm. Sci., Hokkaido Univ., 2. Pharm., Kanazawa Univ., 3. Res. Inst. Microbial Diseases, Osaka Univ., 4. Adv. Preventive. Med. Sci. Res. Center., Kanazawa Univ., 5. GSD, Hokkaido Univ.)

[29P-pm160]Mode of inclusion complex formation of 4-phenylbutyrate and its related compounds with cyclodextrins

○Keishi Yamasaki1,2, Kindness Lomotey Commey1, Akari Nakatake1, Airi Enaka1, Ryota Nakamura1, Koji Nishi1,2, Kenji Tsukigawa1,2, Hirohito Ikeda3, Koki Yamaguchi1,2, Daisuke Iohara1,2, Fumitoshi Hirayama1,2, Otagiri Masaki1,2 (1. Fac. Pharm. Sci., Sojo Univ., 2. DDS Res. Inst., Sojo Univ., 3. Fac. Pharm. Sci., Fukuoka Univ.)

[29P-pm161]In vitro cytotoxicity of antitumor-acitive dinuclear platinum(II) complex toward oxaliplatin-resistant colon tumor cell lines

○Masako Uemura1, Hiroki Yoneyama2, Yoshihide Usami2, Shinya Harusawa2, Seiji Komeda1 (1. Fac. Pharm. Sci., Suzuka Univ. Med. Sci., 2. Fac. Pharm. Sci., Osaka Med. Pharm. Univ.)

[29P-pm162S]A novel eight-membered ring chelate complexes formed by antitumor-active azolato-bridged dinuclear platinum(II) complex with adenosine

○Takuma Yamada1, Masako Uemura1, Katsuhiko Minoura2, Seiji Komeda1 (1. Fac. Pharm. Sci., Suzuka Univ. Med. Sci., 2. Fac. Pharm., Osaka Med. Pharm. Univ.)

[29P-pm163]Binding reaction of 1-methylimidazole to water-soluble non-planar porphyrin iron(III) complexes

○Hirofumi Konno1, Yasushi Kishimoto1 (1. Fac. Pharm. Sci., Teikyo Univ.)

[29P-pm164]Electrochemical reaction of [Fe(CN)6]3- on the Au electrode modified with layer by Layer thin film composed of PAMAM

○Shigehiro TAKAHASHI1, Marina Shizuka1, Iwao Suzuki1 (1. Grad. Sch. Pharm., takasaki Univ. of health and welfare)

[29P-pm165]Analysis of the oxidative degradation mechanism of RNA analog drugs using electrochemistry and DFT methods

○Nakayama Tatsushi1, Bunji Uno2 (1. Gifu Pharmaceutical University, 2. Gifu University of Medical Science)

[29P-pm166]Electrochemical enzyme activity assay using organocatalysts

○Tetsuya Ono1, Kentaro Yoshida1, Katsuhiko Sato2, Yoshitomo Kashiwagi1 (1. Sch. Pharm. Sci., Ohu Univ., 2. Sch. Pharm. Sci., Tohoku Med. and Pharm. Univ.)

[29P-pm167]Electrochemical redox control of P450 and hydroxylation of vitamin D3

○Yasuhiro Mie1, Chitose Mikami1, Yoshiaki Yasutake2, Naoki Matsuda3 (1. Biopro. Res. Inst., AIST, 2. AIST-Waseda Univ. CBBD-OIL, 3. SSRC, AIST)

[29P-pm168]Investigation of through-space interaction with neighboring groups on disulfide oxidation

○Takuhei Yamamoto1,2,3, Yoshihiro Ohsumi1, Yukihiro Esaka1,2,3 (1. Gifu Pharm. Univ., 2. United Grad. Sch., Gifu Univ., 3. COMIT)

[29P-pm169S]Antiglycation activity and antioxidation effects of polyphenol component derived from Chaga mushroom

○Sayaka Eiyama1, Naoki Doi1, Kazuichi Araki2, Yoichiro Fukuta2, Yukinori Yamauchi3, Yasushi Sasai4, Masayuki Kuzuya1, Shin-ichi Kondo1 (1. Lab Pharm. Phys. Chem., Gifu Pharm.Univ., 2. Be・GLAD ichiyo Co., Ltd., 3. Dep. Pharm. Phys.Chem., Matsuyama Univ., 4. Fac.Pharm., Gifu Univ. Med Sci.)

[29P-pm170S]Development of Gel Derived from Natural Polymer Containing Epigallocatechin Gallate for Treatment of Canine Periodontal Disease

○Haruka Maeda1, Tomonori Ohata1, Hiroyuki Tsutsumi1, Rie Nakashima1, Hirohito Ikeda1 (1. Fac.Pharm.Sci.,Fukuoka Univ.)

[29P-pm171S]Development of Oral Film Containing Hinokitiol for Treatment of Periodontal Disease

○Izumi Kaku1, Tomonori Ohata1, Rie Nakashima1, Hiroyuki Tsutsumi1, Hirohito Ikeda1 (1. Fac. Pharm. Sci., Fukuoka Univ.)

[29P-pm172S]Study of Drug Removal Method from Aquatic Environment using Cucurbit[7]uril

○Ami Okamura1, Mai Inadomi1, Rie Nakashima1, Hiroyuki Tsutsumi1, Tomonori Ohata1, Hirohito Ikeda1 (1. Fac. Pharm. Sci., Fukuoka Univ.)

[29P-pm173S]NMR Study on Formation of Inclusion Complex between Antibiotics and Cucurbit[7]uril

○Mai Inadomi1, Ami Okamura1, Rie Nakashima1, Hiroyuki Tsutsumi1, Tomonori Ohata1, Hirohito Ikeda1 (1. Fac. Pharm. Sci., Fukuoka Univ.)

[29P-pm174S]Liquid and Solid Phase Amounts of Active Ingredients in base of Steroid Ointments : Betamethasone Dipropionate Ointment

○Arisa Nakahara1, Tomonori Ohata1, Rie Nakashima1, Hiroyuki Tsutsumi1, Hirohito Ikeda1 (1. Fac. Pharm. Sci., Fukuoka Univ.)

[29P-pm175S]Effect of Concentration in Total Parenteral Nutrition on Stability of Lipid Emulsions

○Ruka Obata1, Tomonori Ohata1, Hiroyuki Tsutsumi1, Rie Nakashima1, Hirohito Ikeda1 (1. Fac.Pharm. Sci.,Fukuoka Univ.)
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