The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama)
Advanced Search

Session Details

Poster Presentation(A) Pharmaceutical Chemistry

Drug design/Screening/adioisotopes, radiopharmaceuticals/Others

Sat. Mar 30, 2024 1:30 PM - 5:00 PM JST
Sat. Mar 30, 2024 4:30 AM - 8:00 AM UTC
[Poster 3] Exhibition Hall AB (1F)

[30P-pm094]Discovery of hydrophobic pockets near the GAA active site and creation of selective chaperone compounds against Pompe disease.

○Atsushi Kato1, Izumi Nakagome2, Maki Kise1, Kousuke Yoshimura1, Takuya Okada3, Naoki Toyooka3, Nobutada Tanaka2 (1. Department of Hospital Pharmacy, University of Toyama, 2. School of Pharmaceutical Sciences, Kitasato University , 3. Graduate School of Science and Engineering, University of Toyama)

[30P-pm095]In silico analyses of the hydrophobic derivatives of an imino sugar aided in the development of the pharmacological chaperones for GAA

○Izumi Nakagome1, Atsushi Kato2, Maki Kise2, Yuna Shimadate2, Tomoki Yoshida1, Noriyuki Yamaotsu1, Nobutada Tanaka1 (1. Kitasato Univ., Sch. Pharm., 2. Department of Hospital Pharmacy, University of Toyama)

[30P-pm096S]Development of peptides that inhibit the Wnt/β-catenin signaling pathwayusing in silico approach

○Minami Fujita1,2, Amika Kikuchi1, Kyohei Arita1, Takashi Misawa2, Yosuke Demizu1,2 (1. Grad. Sch. Med. Life Sci., Yokohama City Univ., 2. NIHS)

[30P-pm097]A novel inhibitor of succinyl CoA:3-ketoacid CoA transferase (SCOT) with reduced brain penetration maintains glucose-lowering actions in experimental obesity

○Seyed Amirhossein Tabatabaei Dakhili1, Kunyan Yang1, Rabih Abou Farraj2, Hamdah Al-Nebaihi1, Christina Saed1, Rakesh Bhat2, Amanda Greenwell1, Jordan Chan1, Indiresh Mangra-Bala1, Keshav Gopal1, Tanin Shafaati1, Farah Eaton1, Sally Ferrari1, Carlos Velazquez-Martinez1, MIchael Overduin2, Mark Glover2, Dion Brocks1, John Ussher1 (1. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., 2. Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada.)

[30P-pm098]Intracellular Nrf2 activating effect of naphthalene derivatives bearing acetoamide in the side chain

○Daisuke Yasuda1, Daisuke Inoue1, Mayu Sugimoto1, Kazuma Kaitoh2, Tomoyuki Ohe3, Tomoya Hirano1 (1. Fac. Pharm., Osaka Med. and Pharm. Univ., 2. Grad. Sc. Inf., Nagoya Univ., 3. Fac. Pharm., Keio Univ.)

[30P-pm099S]Synthesis of Boronic Acid Ester Homodimer with Weakened Thermodynamic Stability

○Aya Makino1, Kaori Ota1, Makoto Furutachi1 (1. Pharm. Sci., Fukuoka Univ.)

[30P-pm100S]Synthesis of Small Molecule Drug Candidate Compounds that Inhibit KDEL Receptors

○Taiki Matsusaki1, Kaori Ota1, Takanori Kitaguchi2, Toshiyuki Tsunoda2, Makoto Furutachi1 (1. Pharm. Sci., Fukuoka Univ., 2. Med., Fukuoka Univ.)

[30P-pm101][Withdrawn]

[30P-pm102S]Synthesis of Planar Inclusion Compounds that Recognize Neurotransmitters

○Rina Matsuda1, Kaori Ota1, Makoto Furutachi1 (1. Pharm. Sci., Fukuoka Univ.)

[30P-pm103S]Structure-activity relationship study of phenylferrocene-based androgen receptor antagonists

○Ryo Yonezawa1, Kotaro Ochiai1, Hiroyuki Kagechika1, Shinya Fujii1 (1. IBB, Tokyo Medical and Dental Univ)

[30P-pm104S]Development of low molecular anti-HIV-1 agents based on HIV-1 capsid protein

○Saho Machida1, Takuya Kobayakawa1, Masaru Yokoyama2, Masayuki Fujino3, Moemi Kaneko1, Masaki Kuraue1, Sayaka Baku1, Takato Onishi1, Osamu Kotani2, Kouhei Tuji1, Tsutomu Murakami3, Hironori Satou2, Hirokazu Tamamura1 (1. Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental Univ., 2. Pathogen Genomics Center, National Institute of Infectious Diseases, 3. AIDS Research Center, National Institute of Infectious Diseases)

[30P-pm105S]ODTAA derivatives and in situ click chemistry to discover novel MBL inhibitors

○Tomohiro Suzuki1, Akari Ikeda1,2, Masako Honsho1,2, Yoshihiko Noguchi1,2, Kiki Nakazato1, Koudai Tomiyama1, Yoshiki Ikegaya1, Yukihiro Asami1,2, Tomoyasu Hirose1,2, Toshiaki Sunazuka1,2 (1. Grad. Sch. of Infect. Ctl., Kitasato Univ., 2. Ōmura Satoshi Memorial Inst., Kitasato Univ.)

[30P-pm106S]Development of a hybrid compound of a small molecule CD4 mimic with a polyethylene glycol as an HIV entry inhibitor

○Yuki Kuroda1, Takuya Kobayakawa1, Kohei Tsuji1, Kiju Konno1, Nami Ohashi1,2, Ami Masuda1, Yutaro Miura1, Takeo Kuwata3, Kazuhisa Yoshimura4, Tomoyuki Miura5, Shigeyoshi Harada6, Shuzo Matsushita3, Hirokazu Tamamura1 (1. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2. Showa Pharmaceutical University, 3. Joint Research Center for Human Retrovirus Infection, 4. Tokyo Metropolitan Institute of Public Health, 5. Institute for Frontier Life and Medical Sciences, Kyoto University, 6. AIDS Research Center, National Institute of Infectious Diseases)

[30P-pm107S]Design and syntheses of vanilloid-coumarin chimera compounds inhibiting both acetylcholinesterase and amyloid-β aggregation.

○Yuki Inomata1, Koji Uwai1 (1. Muroran Institute of Technology, Muroran Institute of Technology, Graduate School of Engineering)

[30P-pm108]xenoBiotic: chemical toxicity prediction software package (2023)

○Toshihiko Sawada1,2, Tomohiro Hashimoto2, Hiroaki Wasada2 (1. xenoBiotic Inc., 2. Faculty of Regional Studies, Gifu Univ.)

[30P-pm109]Syntheses of 2-(2-tetrazol-2-yl)ethyl-1,25-dihydroxy-19-norvitamin D3 and their metabolism

○MASASHI Takano1, KAORI Yasuda2, HIROKI Mano2, TOSHIYUKI Sakaki2, ATSUSHI Kittaka1 (1. Teikyo Univ., 2. Toyama Pref. Univ.)

[30P-pm110S]Identification of small molecules that inhibit heterochromatin protein 1 (HP1)

○Akari Tokuyama1, Yasunobu Yamashita1, Ryo Maeda2, Yuri Takada1, Yukihiro Itoh1, Makoto Tachibana2, Takayoshi Suzuki1 (1. SANKEN, Osaka Univ., 2. FBS, Osaka Univ.)

[30P-pm111]Development of 5-aminolevulinic acid derivatives with GSH depletion capability

○Naoki Yamada1, Yasuyuki Tsunoi1 (1. National Defense Medical College)

[30P-pm112S]Construction of a GLS1 PROTAC library using click chemistry

○Mirei Hayashi1, Yukihiro Itoh1, Yasunobu Yamashita1, Yuri Takada1, Takayoshi Suzuki1 (1. SANKEN, Osaka Univ.)

[30P-pm113S]Application and consideration of compound filters to virtual chemical library

○Yosuke Kikuchi1, Tadahaya Mizuno1, Shumpei Nemoto1, Hiroyuki Kusuhara1 (1. Grad. Sch. Pharm. Sci., The University of Tokyo)

[30P-pm114S]Screening for small molecule compounds targeting immune checkpoint molecules

○Hironobu Hayashi1, Sai Nagaoka2, Yukito Umeno1, Chiharu Kurumada1, Miku Watanabe1, Taiki Ichida2, Hisashi Murakami2, Naohisa Ogo2, Akira Asai2 (1. Division of Pharmaceutical Sciences, Univ. of Shizuoka, 2. Graduate Division of Pharmaceutical Sciences, Univ. of Shizuoka)

[30P-pm115]Screening for SARS-CoV-2 antiviral drugs using small-molecule microarray with amorphous carbon plates

○Hisashi Murakami1, Katsumi Ohta1, Yasushi Takebayashi1,2, Suzuka Makita1, Naohisa Ogo1, Akira Asai1 (1. Grad. Div. Pharm. Sci., Univ. Shizuoka, 2. Nippon Light Metal Company, Ltd.)

[30P-pm116]Combination of Big Data Analysis and Experimental Methods to Find Compounds that Prevent Carfilzomib Side Effects

○Shuhei Nakao1, Kenta Yamaoka2, Tadashi Shimizu1, Yuzuki Moriyama1, Ken-ichi Kiyomiya1 (1. Sch. Pharm. Hyogo Medical Univ., 2. Kobe City Medical Center General Hosp.)

[30P-pm117]Optimization Study of F-18 Indirect Labeling Reagents Boronic Acid Derivatives 3-[18F]TDBFB and 4-[18F]TDBFB

○yusuke yagi1,3,4, Hiroyuki Kimura2, Takahiro Higuchi3,4 (1. Kyoto College of Medical Science, 2. Grad. Sch. Pharm. Sci., Kyoto Pharmaceutical Univ., 3. Comprehensive Heart Failure Center, University Hospital of Würzburg, 4. Grad. Sch. Med. Dent. Pharm. Sci., Okayama Univ.)

[30P-pm118S]An efficient synthesis of [1-13C]-L-tryptophan and [1-13C]-L-5-hydroxytryptophan

○Kano Komiyama1, Yukito Iio1, Makoto Sato1, Azusa Nakayama1, Yuka Nakai1, Shiho Usui1, Moe Kouma1, Tomohiro Takahashi1, Hanae Mitsutake1, Yasuhiro Kajiwara1 (1. Dept. Pharm. Sci., Yokohama Univ. Pharm.)

[30P-pm119]A risk assessment of N-nitrosamine formation using in silico approach

○Genichiro Tsuji1, Takashi Kurohara1, Hidetomo Yokoo1, Sayaka Masada1, Nahoko Uchiyama1, Eiichi Yamamoto1, Yosuke Demizu1,2,3 (1. National Institute of Health Sciences, 2. Grad. Sch. Med., Dent. Pharm. Sci., Okayama Univ., 3. Grad. Sch. Med. Life Sci., Yokohama City Univ.)

[30P-pm120]Syntheses of 5-aminolevulinic acid-cyclic RGD conjugates through a linker responsive to reducing environments

○Shun-ichi Wada1, Azusa Yamada1, Junsuke Hayashi1, Hidehito Urata1 (1. Fac. Pharm, Osaka Med. Pharm. Univ.)
Back to Category List