Presentation Information
[P-20-01]The higher ability of verbal fluency and attention and processing speed with clinical recovery in patients with schizophrenia than remitted patients through the comparison of schizophrenia and healthy controls: A cross-sectional study
*Ryo Asada, Hitoshi Iida, Leo Gotho, Kiyohiro Yasumatsu, Hikaru Hori (Department of Psychiatry, Faculty of Medicine, Fukuoka University(Japan))
Keywords:
Schizophrenia,Cognitive function,Recovery,Remission
Cognitive impairment is one of the core symptoms with schizophrenia (Jauhar et al., 2022) and several domains of cognitive function in patient with schizophrenia were associated with real world functions (Harvey et al., 2022). Regarding functional recovery with schizophrenia, only one cross-sectional study reported that the score of executive function, verbal fluency and verbal working memory in recovery patients with schizophrenia were higher than non-recovered patients (Kopelowicz et al., 2005). However, there are no evidence about the difference of cognitive function and relationships with social skills between recovery and remission states with schizophrenia. This cross-sectional study investigated that 55 patients with schizophrenia and 20 healthy controls. 25 schizophrenia patients were meted recovery criteria, and 30 patients were meted remission criteria. We used the Japanese version of the Brief Assessment of Cognition in Schizophrenia (BACS-J) to evaluate cognitive function. The Brief Psychiatric Rating Scale (BPRS) and the Calgary and Depression Scare for Schizophrenia (CDSS) were used to evaluate psychiatric symptoms. Social function was measured by the Japanese version of social functioning scale (SFS-J). This study was approved by the Fukuoka University Medical Ethics Committee (U-21-11-018), and verbal and written consent was obtained from all participants. In the demographics and clinical characteristics of each group, there was no significant difference except for education, duration of employment, and duration of illness. Each BACS-J score except for executive function was significant difference among three groups. From the post-hoc analysis, verbal fluency and attention and processing speed in recovery group were significantly higher than remission group but verbal fluency was no significant difference between recovery and healthy control group. The present study show that a part of cognitive functions might be relate to recovery for patients with schizophrenia. Furthermore, it may be important to focus on improving these cognitive functions for achieving recovery.