Presentation Information
[SY-108]Recent Advances and Future Directions in Nuroimaging and Neurophysiological Studies in Schizophrenia
Yoji Hirano1, Shunsuke Koike2, Ming H. Hsieh3, Tao Li4 (1.University of Miyazaki(Japan), 2.University of Tokyo(Japan), 3.National Taiwan University(Taiwan), 4.Zhejiang University School of Medicine(China))
In recent years, advancements in technologies such as magnetic resonance imaging (MRI), functional brain imaging, electroencephalography (EEG), and magnetoencephalography (MEG) have progressively revealed insights into the neurobiological underpinnings of patients with schizophrenia. However, current neuroimaging methods and studies limited to single institutions have not yet fully illuminated the disorder's pathological basis and its heterogeneity. As a result, the development of biomarkers for clinical applications, including differential diagnosis and assessment of disease states, has been notably slow. To tackle this challenge, it is essential to identify robust biomarkers and rigorously validate their reproducibility. This should be accompanied by large-scale, multi-institutional investigations, as well as multimodal assessments that integrate diverse biomarkers. Additionally, establishing biologically informed subtyping frameworks and translating these findings into personalized therapeutic strategies in clinical practice is crucial. This symposium will feature leading researchers from Japan, Taiwan, and China who are at the forefront of schizophrenia research. They will present and discuss the latest discoveries, emerging trends, and future directions in the field.