Presentation Information

[SY-28]Neurophysiological studies from a perspective of predictive coding in psychiatry

Kenji Kirihara1, Minah Kim2, Daisuke Koshiyama3, Zenas C. Chao4, Takanori Uka5 (1.Center for Coproduction of Inclusion, Diversity and Equity, The University of Tokyo(Japan), 2.Department of Neuropsychiatry, Seoul National University Hospital(Korea), 3.Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo(Japan), 4.International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo(Japan), 5.Department of Integrative Physiology, Graduate School of Medicine, University of Yamanashi(Japan))
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Keywords:

predictive coding,electroencephalography,electrocorticography,mismatch negativity

Recently, a predictive coding theory is thought to provide a useful framework for understanding various symptoms of psychiatric disorders. In the predictive coding theory, the brain generates a model of the world and updates the model by calculating the differences between prediction based on the model and sensory inputs from the world. Alterations in these processes generate a maladaptive model and make a false inference that leads to various symptoms in psychiatric disorders.
In this symposium, 4 speakers will show recent neurophysiological studies that investigate neurobiological mechanisms underlying altered predictive coding in psychiatric disorders. These speakers will show neurophysiological studies of predictive coding using electrocorticography (ECoG) of non-human primates and electroencephalography (EEG) of humans with and without psychiatric disorders. EEG studies of patients with psychiatric disorders are important for clarifying how predictive coding is altered in psychiatric disorders. EEG studies of healthy humans are important for clarifying how predictive coding is presented in human brains. ECoG studies of non-human primates are important for clarifying neurobiological mechanisms underlying predictive coding.
Combining ECoG studies of non-human primates and EEG studies of humans with and without psychiatric disorders will lead to translational studies that are useful for understanding psychiatric disorders and developing better treatment. This symposium will provide the opportunity to show Asian network of neurophysiological studies based on the concept of predictive coding in psychiatry.