Presentation Information
[SY-8]Recent advancements in schizophrenia research; Asian perspectives
Tsuyoshi Akiyama1, Yi-Chun Liu2, Tomiki Sumiyoshi3, Tao Li4, Toshiyia Murai5 (1.Rokubancho Mental Clinic(Japan), 2.Changhua Christian Children's Hospital(Taiwan), 3.National Center of Neurology and Psychiatry(Japan), 4.Zhejiang University(China), 5.Kyoto University(Japan))
Keywords:
Schizophrenia,Asia,Psychiatry
Schizophrenia remains a most enigmatic and challenging mental illness. However, there have been gradual advancements in research and practices. In this symposium, there will be progress reports from Taiwan, China and Japan. Vincent Chin-Hung Chen presents insight into the possible associations and shared common pathology between schizophrenia and type 1 Diabetes Mellitus. He concludes potential shared immunopathology, such as Th17 dysfunction, may explain the observed associations. Longitudinal, population-based studies are essential to deepen the understanding of these conditions and inform improved prevention and treatment strategies. Tomiki Sumiyoshi reports on cognitive impairment associated with schizophrenia (CIAS). CIAS is present in most patients and may determine functional outcomes. However, assessments of cognitive function using appropriate instruments are not always conducted in routine clinical practice. He will address the current state of recognition of CIAS among patients and physicians and discuss how the prospective establishment of cognition-enhancing interventions will facilitate efforts to support the personal recovery of patients with schizophrenia. Tao Li’s presentation will focus on the exploration of the biological mechanisms underlying schizophrenia and related disorders. She will adopt a cross-disorder perspective to examine this topic, which is essential for understanding the common and unique biological factors that contribute to these conditions. This approach will facilitate a comprehensive understanding of the shared and distinct biological aspects across different disorders. Finally, Toshiya Murai's talk will focus on psychosis, which is the core symptom of schizophrenia. Although psychosis is inherently a subjective symptom, he will propose a way to conceptualize it in an objective way. He will also propose a novel computational model of psychosis that we can test in future empirical investigations including neuroimaging studies.