Presentation Information
[F2-06]Interleukin-33 bridges TBK1-MyD88 signaling and CD8+ T cell activation in lipid nanoparticle mRNA vaccination
*Kaiwen Liu1, Kouji Kobiyama1, Naoko Satoh-Takayama2, Tomoya Hayashi1, Burcu Temizoz1, Hideo Negishi1,3, Asuka Joy Tobuse1, Mai Onaga1, Areej Sakkour1, Peter D Katsikis4, Cevayir Coban5, Ken J Ishii1 (1. The Division of Vaccine Science, the Institute of Medical Science, the University of Tokyo (Japan), 2. Precision Immune Regulation RIKEN ECL Research Unit, RIKEN Center for Integrative Medical Sciences (Japan), 3. Laboratory of Immunology and Infection Control, Institute for Quantitative Biosciences, the University of Tokyo (Japan), 4. Department of Immunology, Erasmus University Medical Center (Netherlands), 5. Division of Malaria Immunology, the Institute of Medical Science, the University of Tokyo (Japan))
Keywords:
mRNA vaccine,IL-33,CD8+ T cell,fibroblast
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