講演情報

[WS11-08-P]Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients

^○Ryuji Owada¹, Takeru Kashiwada², Ryotaro Takano^1,3, Fumihiko Ando^1,3, Shoko Kuroda¹, Yoshishige Miyabe^1,4, Tomoko Asatsuma-Okumura¹, Masahiro Seike², Yoshiko Iwai¹ (1.Department of Cell Biology, Institute of Advanced Medical Sciences, Nippon Medical School, 2.Department of Pulmonary Medicine and Oncology, Nippon Medical School, 3.Department of Gastrointestinal and Hepato-Biliary-pancreatic surgery, Nippon Medical School, 4.Department of Immunology and Parasitology, St. Marianna University School of Medicine)

キーワード：

soluble PD-L1、inflammation、macrophage、lysosomal degradation、immune-related adverse event

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