講演情報

[WS22-24-O/P]Deletion of the endoribonuclease Regnase-1 unleashes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

Yasuharu Nagahama1,2, Shizuo Akira1,3,4 (1.Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 2.Host Defense Laboratory, Immunology Unit, Osaka Research Center for Drug Discovery, Otsuka Pharmaceutical Co., Ltd., 3.Center for Advanced Modalities and Drug Delivery System, Osaka University, 4.Department of Host Defense, Research Institute for Microbial Diseases, Osaka University)

キーワード:

Regnase-1、NK cells、anti-tumor immunity、Ifng transcription、OCT2、tumor microenvironment

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