講演情報

[WS28-10-O/P]RNA helicase DDX6 plays a role in inflammatory diseases through the IL-6 amplifier, an enhanced activation of NF-κB in non-immune cells

Shintaro Hojyo1,2,3, Seiichiro Naito1,4, Hiroki Tanaka1, Jing-Jing Jiang1, Masato Tarumi1, Ari Hashimoto5, Yuki Tanaka1,2, Kaoru Murakami1, Shimpei I Kubota1,2, Shigeru Hashimoto1,3, Masaaki Murakami1,2,3,6 (1.Division of Molecular Psychoneuroimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, 2.Quantum Immunology Team, Institute for Quantum Life Science, National Institute for Quantum and Radiological Science and Technology (QST), 3.Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, 4.Department of Cardiovascular Medicine, Graduate School of Medicine, Hokkaido University, 5.Department of Molecular Biology, Graduate School of Medicine, Hokkaido University, 6.Division of Molecular Neuroimmunology, National Institute for Physiological Sciences, National Institutes of Natural Sciences)

キーワード:

Inflammation、IL-6、STAT3、NF-κB、DDX6

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