講演情報
[WS28-17-O/P]5,6-dimethylxanthenone-4-acetic acid (DMXAA), a Partial STING Agonist, Competes for Human STING Activation
○Burcu Temizoz1,2,5, Takayuki Shibahara3, Tomoya Hayashi1,2,5, Kouji Kobiyama1,2,5, Erdal Sag6, Atsushi Kumanogoh7,3, Masahiro Yamamoto7,8, Mayda Gursel9, Seza Ozen6, Etsushi Kuroda10, Cevayir Coban2,4,7,5, Ken J Ishii1,2,7,5 (1.Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 2.International Vaccine Design Center (VDesC), The Institute of Medical Science (IMSUT), The University of Tokyo, Tokyo, Japan., 3.Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan., 4.Division of Malaria Immunology, Department of Microbiology and Immunology, The Institute of Medical Science (IMSUT), The University of Tokyo, Tokyo, Japan., 5.Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan., 6.Department of Pediatric Rheumatology, Hacettepe University, Ankara, Türkiye., 7.Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan., 8.Department of Immunoparasitology, Division of Infectious Disease, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan., 9.MG Laboratory on Vaccines and Immunotherapeutics, Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Türkiye., 10.Department of Immunology, School of Medicine, Hyogo Medical University, Hyogo, Japan.)
キーワード：
DMXAA、STING、SAVI、partial agonist、HHMX
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