セッション詳細
[WS(P)02]Cytotoxic T cells
2024年12月3日(火) 16:50 〜 17:35
Poster 2
[WS02-01-P]Single-cell transcriptome analysis unveils a distinctive subpopulation of CD8 T cells expressing PRDM1 in Kawasaki disease patients with coronary artery lesions.
○HO-CHANG KUO1,2 (1.Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan., 2.Kawasaki Disease Center, Taiwan)
[WS02-02-P]CD8-dependent contact hyper sensitivity is regulated by Themis
○Masayuki Kitajima, Toshiyuki Okada, Harumi Suzuki (Dept. of Immunology and Pathology, Research Institute National Center for Global Health and Medicine)
[WS02-03-O/P]The transcription factor BATF pioneers the effector differentiation of CD8+ T cells through direct interaction with IRF4
○Sotaro Fujisawa1, Yamato Tanabe1, Toshikatsu Tamai1, Junko Kurachi1, Miki Koura1, Yusuke Miyanari2, Makoto Kurachi1 (1.Department of Molecular genetics, Faculty of Medical Sciences, Kanazawa University, 2.WPI Nano Life Science Institute, Kanazawa University)
[WS02-04-O/P]Fate inflexibility of virtual memory CD8 T cells during chronic infection
○Yamato Sajiki1, Koichi Araki1,2 (1.Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA, 2.Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA)
[WS02-05-P]The Arf pathway is required for the survival of CD8+ T cells stimulated with strong TCR signal
○Mami Sumiyoshi1, Yoichi Maekawa2,3, Satoshi Matsuda1 (1.Dept of Cell Signaling, Inst. of Biomed. Sci., Kansai Med.Univ., 2.Dept. of Pathol. & Infectious Diseases, Gifu Univ., 3.G-CHAIN. Gifu Univ.)
[WS02-06-O/P]Efficient inhibition of DNAM-1 clustering via sequestrating CD155 from DNAM-1-TCR microclusters by CD96 with height
○Ei Wakamatsu, Ann Hattori, Hiroaki Machiyama, Hiroko Toyota, Masae Furuhata, Ryuji Hashimoto, Hitoshi Nishijima, Arata Takeuchi, Tadashi Yokosuka (Tokyo Medical Univ.)
[WS02-07-P]Glycolysis in CD8+ T cells plays a major role in the onset of immune-mediated HLA-related idiosyncratic drug-induced toxicity
○Takeshi Susukida1, Yuchen Sun2, Noriaki Arakawa2, Takuya Hirao3, Shigeki Aoki4, Kousei Ito4, Yoshihiro Hayakawa1 (1.Laboratory of Cancer Biology and Immunology, Section of Host Defenses, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2.Division of Medicinal Safety Science, National Institute of Health Sciences, 3.Divisions of Clinical Pharmacokinetics, Department of Pharmaceutical Sciences, International University of Health and Welfare, 4.Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University)
[WS02-08-P]Chemically-Defined, Animal-Origin Free Medium for hPSC derived CD8 T Cell Differentiation
○Jessica Chang, Yasuyuki Kita, Hirotaka Wagatsuma (Ajinomoto Co., Inc)
[WS02-09-O/P]Dysfunctional Mitochondria Promote DNA Damage and T Cell Exhaustion in CD8+ T Cells
○Kung-Chi Kao1,2, Yu-Ming Chuang1,2, Yi-Ru Yu3, Bugi Ratno Budiarto4, Shih-Yu Chen4, Ping-Chih Ho1,2 (1.University of Lausanne, 2.Ludwig Institute for Cancer Research, 3.Pilatus Biosciences, 4.Academia Sinica)
[WS02-10-P]Strategic regulation of T cell exhaustion by vitamin D via alternative splicing
○Mayumi Mori1, Taro Tsujimura2, Takuya Yamamoto2,3,4, Yo-ichi Nabeshima1 (1.Graduate School of Medicine, Kyoto University, 2.Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, 3.Center for iPS Cell Research and Application (CiRA), Kyoto University, 4.Medical-Risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP))
[WS02-11-P]Sustainability of memory CD8+ T cell upon repetitive antigen stimulation
○Yamato Tanabe, Makoto Kurachi, Sotaro Fujisawa (Department of Molecular Genetics, Kanazawa University)
[WS02-12-O/P]Vitamin C treatment enhances the immune responses of CD8+ T cells by upregulation of Batf3
○Kenta Kondo1, Mina Kumode1,2, Koji Terada1, Yasutoshi Agata1 (1.Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, 2.Department of Hepatology, Shiga University of Medical Science)
[WS02-13-O/P]Identification of human CD8+ T cells recognizing viral lipopeptides
○Minori Asa1,2, Sho Yamasaki1,2,3 (1.Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 2.Laboratory of Molecular Immunology, Immunology Frontier Research Center (iFReC), Osaka University, 3.Center for Infectious Disease Education and Research (CiDER), Osaka University)
[WS02-14-P]Examination to reveal mechanisms for suppression of cytotoxic T lymphocyte activation by target cells
○Hidefumi Kojima1, Yuji Nakai2 (1.Division for Technical Support, Center for Research Collaboration and Support, Dokkyo Medical Univ. Sch. of Med., 2.Section of Food Sciences, Institute of Regional Innovation, Hirosaki University)
[WS02-15-P]Elucidation of the functional sites of Nkg7 in its cellular localization and the release of cytotoxic granules
○Ryosuke Kumagai, Hiroaki Takimoto, Koji Eshima (Division of Immunology, Kitasato University Graduate School of Science)
[WS02-16-O/P]Histone deacetylase 1 controls the generation and maintenance of effector-like CD8+ T cells during chronic viral infection
Ramona Rica1, Monika Waldherr1, Marlene Schülein1, Emi Miyakoda1, Thomas Krausgruber2, Christoph Bock2,3, Nicole Boucheron1, Wilfried Ellmeier1, ○Shinya Sakaguchi1 (1.Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Division of Immunobiology, 2.CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 3.Medical University of Vienna, Center for Medical Data Science, Institute of Artificial Intelligence)