セッション詳細
[WS(P)09]Mucosal-Skin Immunity 2
2024年12月3日(火) 16:50 〜 17:35
Poster 9
[WS09-01-O/P]Sulfated glycans in intestinal homeostasis and disease
○Shota Okamoto1, Ryu Okumura1,2, Kiyoshi Takeda1,2 (1.Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, 2.WPI Immunology Frontier Research Center, Osaka University)
[WS09-02-O/P]Novel Metabolites Altered by Appendectomy Lead to Tuft Cell Hyperplasia and Play an Important Role in the Amelioration of Ulcerative Colitis
○Shunya Hatai1,2, Yasutaka Motomura2,3,4, Koji Hosomi5, Taiki Sakaguchi6, Ryu Okumura6, Takayuki Ogino7, Daisuke Motooka8, Eiichi Morii9, Shota Nakamura8, Kiyoshi Takeda6, Jun Kunisawa5, Kazuyo Moro1,2,3 (1.Laboratory for Innate Immune Systems, RIKEN-IMS, 2.Laboratory for Innate Immune Systems, Graduate School of Medicine, Osaka University, 3.Laboratory for Innate Immune Systems, iFReC, Osaka University, 4.Division of Immunology and Allergy, Research Institute for Biomedical Science, Tokyo University of Science, 5.Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN), 6.Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, 7.Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 8.Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, 9.Department of Pathology, Graduate School of Medicine, Osaka University)
[WS09-03-O/P]Crucial Role of Pancreatic GP2 in Regulating Bacterial Translocation and Organ Failure
○Yosuke Kurashima1,2,3, Zhongwei Zhang1, Yun-Gi Kim4, Nozomu Obana5, Shinji Fukuda5,6, Ryutarou Fukui7, Kensuke Miyake7, Koji Hase8, Hiroshi Ohno9, Satoshi Uematsu10, Peter B Ernst3, Hiroshi Kiyono1,2,3 (1.Department of Innovative Medicine, Graduate School of Medicine, Institute for Advanced Academic Research/ Research Institute of Disaster Medicine, Chiba University, Chiba, Japan, 2.Chiba University Synergy Institute for Futuristic Mucosal Vaccine Research and Development (cSIMVa), Department of Human Mucosal Vaccinology, Chiba University Hospital, Chiba, Japan., 3.Division of Comparative Pathology and Medicine, Chiba University-University of California San Diego Center for Mucosal Immunology, Allergy and Vaccine, School of Medicine, San Diego, CA, USA., 4.Department of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan, 5.Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Ibaraki, Japan, 6.Institute for Advanced Biosciences, Keio University, Yamagata, Japan, 7.Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 8.Division of Biochemistry, Department of Pharmaceutical Sciences, Faculty of Pharmacy, and Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, Japan., 9.Laboratory for Microbiome Sciences and Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., 10.Department of Immunology and Genomics, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan)
[WS09-04-O/P]Loss of claudin-1 in keratinocytes induces itch transmitted by multiple types of sensory nerves
○Susumu Toshima1,2, Sonoko Takahashi1, Ayako Matsuyama1, Akiharu Kubo2,3, Masayuki Amagai2,4, Takaharu Okada1 (1.Laboratory for Tissue Dynamics, Center for Integrative Medical Science, RIKEN, 2.Department of Dermatology, Keio University School of Medicine, 3.Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 4.Laboratory for Skin Homeostasis, Center for Integrative Medical Science, RIKEN)
[WS09-05-O/P]Epithelial barrier dysfunction by intestine-specific AP-1B deficiency causes renal IgA deposition
○Yusuke Kinashi1, Keisuke Tanaka1, Shunsuke Kimura1, Daisuke Takahashi1, Hiroshi Ohno2, Koji Hase1 (1.Division of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Science, Keio University, 2.Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences)
[WS09-06-O/P]Reactive persulfide controls intestinal inflammation by suppressing CD4+ T lymphocyte proliferation
○SHUNICHI TAYAMA1, Yuya Kitamura, Kyoga Hiraide2, Hibiki Suzuki, Jing Li1, Ziying Yang1, Kosuke Sato1, Akihisa Kawajiri3, Yuko Okuyama, Takeshi Kawabe1, Takaaki Akaike4, Naoto Ishii1 (1.Tohoku University Graduate School of Medicine, Department of Microbiology and Immunology, 2.Tohoku University Graduate School of Medicine, Department of AI and Innovative Medicine, 3.Sendai city hospital, 4.Tohoku University Graduate School of Medicine, Department of Environmental Medicine and Molecular Toxicology)
[WS09-07-O/P]M cells in the tear duct-associated lymphoid tissue contribute to the development of allergic conjunctivitis by facilitating germinal-center reaction
○Yuki Oya1, Shunsuke Kimura1,2, Koji Hase1,3,4 (1.Keio Univ., 2.Precursory Research for Embryonic Science and Technology (PRESTO), 3.The Institute of Medical Science, 4.Fukushima Univ.)
[WS09-08-O/P]Identification of staphylococcus aureus genes affecting response to bleach bath therapy in patients with atopic dermatitis
○Hiroshi Kawasaki1,2, Ayano Fukushima-Nomura2, Yoshihiro Ito2, Eiryo Kawakami1, Masayuki Amagai2 (1.RIKEN, 2.Keio Univ.)
[WS09-09-P]Ultraviolet-B irradiation expands skin-resident CD81+Foxp3+ regulatory T cells with a highly activated phenotype
○Hiroaki Shime1, Mizuyu Odanaka1, Masaki Imai1,2, Daisuke Sugiyama1, Shoryu Takayama1, Akimichi Morita3, Sayuri Yamazaki1 (1.Department of Immunology, Nagoya City University Graduate School of Medical Sciences, 2.Department of Medical Technology and Sciences, Faculty of Health Sciences, Kyoto Tachibana University, 3.Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences)
[WS09-10-P]Elucidation of the Mechanism of IgA Induction by Heat-killed Lactic Acid Bacteria
○Jiahui Lyu1,2, Riho Matsumura1,2, Mizusa Suzuki1,2, Peng Gao1, Yasunori Yonejima3, Chiaki Tomimoto3, Reiko Shinkura1 (1.Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, Laboratory of Immunology and Infection Control, 2.Graduate School of Frontier Science, The University of Tokyo, Kashiwa, Chiba, Japan, 3.Noster Inc.)
[WS09-11-P]Characterization of human monocytic cell line THP-1 associated with 3D human skin models under UVA exposure
○Tanapat Palaga1, Suphanun Phuphanitcharoenkun2,3, Fiona Louis4, Rungaroon Waditee-Sirisattha1, Hakuto Kageyama5, Michiya Matsusaki6 (1.Department of Microbiology, Faculty of Science, Chulalongkorn University, 2.Graduate Program in Biotechnology, Faculty of Science, Chulalongkorn University, 3.Center of Excellence in Materials and Bio-interfaces, Chulalongkorn University, 4.Joint Research Laboratory (TOPPAN) for Advanced Cell Regulatory Chemistry, Graduate School of Engineering, Osaka University, 5.Graduate School of Environmental and Human Sciences, Meijo University, 6.Department of Applied Chemistry, Graduate School of Engineering, Osaka University,)
[WS09-12-P]Suppression of STAT3 activation in itch-transmitting sensory neurons by the topical application of delgocitinib to the mouse skin
○Takuma Kanai1,2, Minoru Tateno3, Sonoko Takahashi1, Ayako Matsuyama1, Natsuki Yatsuo1,2, Rumi Sato1, Susumu Toshima1,4, Katsuyo Ohashi-Doi3, Hiroshi Kawasaki1,4, Takaharu Okada1,2 (1.RIKEN Center for Integrative Medical Sciences, 2.Department of Medical Life Science, Yokohama City University, 3.Torii Pharmaceuticals Co., Ltd., 4.Department of Dermatology, Keio University School of Medicine)
[WS09-13-P]A Novel Recombinant Lactococcus lactis Mucosal Vaccine Platform Based on Group A Streptococcus Pili
○Catherine Jia-Yun Tsai1,2,3, Kohtaro Fujihashi3,4, Ken Ishii4, Thomas Proft1,2 (1.University of Auckland, 2.Maurice Wilkins Centre for Molecular Biodiscovery, 3.Chiba University Hospital, 4.University of Tokyo)
[WS09-14-P]Functional interregional heterogeneity of anatomically compartmentalized ILC2s in the intestine
○Yuki Fukushima1, Satoshi Koga1,3, Kazuyo Moro1,2,3 (1.Laboratory for Innate Immune Systems, Graduate School of Medicine, Osaka University, 2.Laboratory for Innate Immune Systems, RIKEN-IMS, 3.Laboratory for Innate Immune Systems, iFReC, Osaka University)
[WS09-15-P]The IL10-IL10R axis in Pdgfra+ fibroblasts is required for the prevention of colitis
○Takayoshi Ito, HIsako Kayama, Kiyoshi Takeda (Osaka Univ.)
[WS09-16-P]Development of three-dimensional printed models of the nasal cavity for evaluation of the in vivo deposition of nasal vaccines
○Yohei Uchida1, Rika Nakahashi1,2, Shingo Umemoto3, Masashi Suzuki3, Hiroshi Kiyono1,2,4,5,6 (1.Department of Human Mucosal Vaccinology, Chiba University Hospital, Chiba, Japan, 2.Synergy Institute for Futuristic Mucosal Vaccine Research and Development (cSIMVa), Chiba University, Chiba, Japan, 3.Department of Otorhinolaryngology and Head & Neck Surgery, Faculty of Medicine, Oita University, 4.Future Medicine Education and Research Organization, Chiba University, Chiba, Japan, 5.Department of Medicine, UC San Diego School of Medicine, San Diego, CA, USA, 6.CU-UCSD Center for Mucosal Immunology, Allergy and Vaccines (cMAV), UC San Diego School of Medicine, San Diego, CA, USA)
[WS09-17-P]Effects of dietary fiber and its metabolites on the small intestinal immune system
○Jigen Sekine1,2, Katsuki Yaguchi1,3, Tadashi Takeuchi1,4, Masami Kawasumi1, Ayumi Ito1, Hiroshi Ohno1,2 (1.Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, 2.Immunobiology Laboratory, Department of Medical Life Science, Graduate School of Medical Life Science, Yokohama City University, 3.Department of Gastroenterology, Graduate School of Medicine, Yokohama City University, 4.Department of Microbiology and Immunology, Stanford University School of Medicine)
[WS09-18-P]Investigating the Impact of Intestinal Microfold Cells on Gut Microbiota Structure and Function Using Synthetic Bacterial Community
○Mitsuki Ito1,2, Shohei Asami1, Tadashi Takeuchi1,3, Takashi Kanaya1, Hiroshi Ohno1 (1.Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, 2.Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 3.Department of Microbiology and Immunology, Stanford University School of Medicine)
[WS09-19-P]Rosiglitazone exerts an anti-fibrotic effect in intestinal fibrosis via TGFβ/Smad and ERK signaling pathways
○Supasuta Leangpanich, Arong Gaowa, Motomu Shimaoka (Mie Univ.)
[WS09-20-P]Pathogenetic analysis of ulcerative colitis-like inflammatory bowel disease using ER-stress reporter gene and HLA-DR4 transgenic mice.
○Atsushi Irie, Ryo Ikeda, Hroyuki Oshiumi (Department of Immunology, Graduate School of Medical Sciences, Kumamoto University)
[WS09-21-P]Conjunctival goblet cell associated antigen passage serves as a target for both allergy prevention and drug delivery
○Yasuharu Kume1,2,3, Tomoaki Ando1, Keiji Matsumoto1,2,3, Meiko Kimura1,2,3, Moe Matsuzawa1,2,3, Kumi Izawa1, Ayako Kaitani1, Nobuhiro Nakano1, Shintaro Nakao3, Nobuyuki Ebihara2, Ko Okumura1, Jiro Kitaura1,4 (1.Atopy (Allergy) research center, Juntendo University Graduate School of Medicine, 2.Department of Ophthalmology, Juntendo University Urayasu Hospital, 3.Department of Ophthalmology, Juntendo University Graduate School of Medicine, 4.Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine)