講演情報
[10p-A13-6]In vivo label-free imaging of tissue microstructure in adult zebrafish using multi-contrast Jones-matrix optical coherence tomography
〇(D)Shadil Basheer1, Yiheng Lim1, Bao Cunyou1, Toshiki Obokata3, Ibrahim Abd El-Sadek2,1, Shuichi Makita1, Makoto Kobayashi3, Yoshiaki Yasuno1 (1.COG, Univ. Tsukuba, 2.Damietta Univ., 3.Univ. Tsukuba Med)
キーワード：
optical coherence tomography、Biomedical imaging、Zebrafish based research
Zebrafish are important biomedical models; however, conventional imaging techniques lack the capability for label-free, in vivo microstructural imaging. To address this limitation, we developed a custom 1.3-μm swept-source Jones-matrix optical coherence tomography (JM-OCT) system. By exploiting polarization-based contrasts, the system reveals sub-resolution microstructural features, such as pigmentation in ocular tissues, collagen-composition in swim bladder walls, the organization of muscle fibers, and pigment distribution in stripes.