講演情報

[9a-PB1-13]Hydrogel encapsulating Physarum polycephalum for biohybrid systems

〇(M2)CAMILLE Gedraga GARNICA1, FRANZ GERHART NELSON TERIO2, GIOVANNI PAYLAGA1, MARK NOLAN CONFESOR1 (1.MSU-IIT, 2.MSU-MARAWI)

キーワード:

Hydrogel、Physarum polycephalum、traction forces

Hydrogels are composed of three-dimensional polymer networks that can absorb large amount of water that can retain their structure with exceptional biocompatibility and versatilityThey are primarily used for biocontainment; however, their mechanical–biological activity interactions have not been explored [1]. In this study, a biological organism called Physarum polycephalum was encapsulated inside the hydrogel sphere. A non-equilibrium oscillatory movement was observed on the surface of hydrogel in the presence of Physarum, likely due the stress induced by its traction forces. While, a monotonic collapse can be observed for a passive hydrogel indicating the absence of an active stresses on its surface. Finite element simulations confirmed these observations by introducing pressure and active forces equations.
References
[1] TC.Tang, et al. Nat.Chem.Biol. 17(6), 724-731 (2021)