セッション詳細
[2S-Aa(English)][Transformative Research Areas (A)] Mechanochemical crosstalk in multicellular movement during development([学変A] 発生における細胞集団運動を創発するメカノケミカルクロストーク)
2024年7月18日(木) 15:00 〜 17:30
A会場 1F 大会議室101
Organizers:Takayuki Suzuki(Osaka Metropolitan University), Hidehiko Hashimoto(Osaka University)
Multicellular movement underlies multicellular morphogenesis and homeostasis during development. While genetic programs pattern multicellular movements through biochemical signaling pathways that act within and between cells, it remains not fully elucidated how self-organized patterns of multicellular movements emerge from dynamic mechanochemical interactions across molecular, cellular and tissue scales. In this symposium, we aim to understand the common and divergent systems underlying the mechanism governing the emergence of patterns of multicellular movements during development through comparing studies across various tissues and animals.
Opening Remarks(はじめに)
Time Adjustment(時間調整)
[2A12]‘Mechano-gradients’ drive morphogen-noise correction to ensure robust patterning(メカノ勾配によるモルフォゲンノイズ除去システムは組織パターン形成の頑強性を支える)
*Kana Aoki1, Tohru Ishitani1 (1. Dept. of Homeostatic Regulation, RIMD, Osaka Univ.)
[2A13]Mechanical transapical coupling of endometrial epithelial cells during implantation
*Jun Sakurai1,2, Noriyuki Kinoshita1,2, Tetsuhisa Otani4, Hiroshi Koyama1,2, Mikio Furuse3,2, Toshihiko Fujimori1,2 (1. National Institute for Basic Biology, 2. SOKENDAI, 3. National Institute for Physiological Sciences, 4. Tokyo Metropolitan University)
[2A14]Mechanochemical control of digit emergence
*Carolina Parada1 (1. Department of Developmental and Stem Cell Biology, Pasteur Institute, Paris, France)
[2A15]A physical role of epithelium in chick limb bud elongation(肢芽の遠近軸に沿った伸長に与える上皮の物理的役割の解明)
Kazuki Kawamura2, Daisuke Ohtsuka3, Yoshihiro Morishita3, *Takayuki Suzuki1 (1. Department of Biology, Faculty of Science, Osaka Metropolitan University, 2. Department of Biology, Faculty of Science, Nagoya University, 3. RIKEN, BDR)
[2A16]An optogenetic toolbox to manipulate integrin adhesion complexes.
Minggang Xiong1, Tsun Lam Leong1, *Heath Ellis Johnson1 (1. The University of Hong Kong)
[2A17]Dynamic separation of cell-cell contacts induces RhoA and Myosin activity to drive zippering and neural tube closure in a simple chordate
*Hidehiko Hashimoto1, Takeo Horie1, Edwin Munro2 (1. Graduate School of Frontier Biosciences, Osaka University, 2. Department of Molecular Genetics and Cell Biology, University of Chicago)