講演情報
[IL1]When One Target Isn’t Enough: Rethinking Neurodegeneration
Edward B. Lee
(University of Pennsylvania)
◆略歴
Edward B. Lee, M.D., Ph.D. is the John Q. Trojanowski, M.D., Ph.D. Professor for Neurodegenerative Disease Research at the University of Pennsylvania, where he serves as Director of the Center for Neurodegenerative Disease Research, Co-Director of the Institute on Aging, and Associate Director of the Penn Alzheimer’s Disease Research Center. A Phi Beta Kappa graduate of Stanford, he earned his M.D. and Ph.D. from Penn and completed training in Anatomic Pathology and Neuropathology.
Dr. Lee’s research focuses on Alzheimer’s disease, frontotemporal dementia (FTD), ALS, and trauma-related neurodegeneration. He has made seminal contributions to understanding TDP-43 dysfunction in FTD/ALS, discovering vacuolar tauopathy linked to VCP mutations, annexin A11 and TDP-43 co-aggregates in FTD, and developing cryo-electron tomography for human brain tissue. An attending neuropathologist at the Hospital of the University of Pennsylvania, he has authored more than 250 publications, serves on multiple journal editorial boards, chairs the NIH CMND/CMN study section, and is deeply committed to mentoring the next generation of scientists and physician-scientists.
(University of Pennsylvania)
◆略歴
Edward B. Lee, M.D., Ph.D. is the John Q. Trojanowski, M.D., Ph.D. Professor for Neurodegenerative Disease Research at the University of Pennsylvania, where he serves as Director of the Center for Neurodegenerative Disease Research, Co-Director of the Institute on Aging, and Associate Director of the Penn Alzheimer’s Disease Research Center. A Phi Beta Kappa graduate of Stanford, he earned his M.D. and Ph.D. from Penn and completed training in Anatomic Pathology and Neuropathology.
Dr. Lee’s research focuses on Alzheimer’s disease, frontotemporal dementia (FTD), ALS, and trauma-related neurodegeneration. He has made seminal contributions to understanding TDP-43 dysfunction in FTD/ALS, discovering vacuolar tauopathy linked to VCP mutations, annexin A11 and TDP-43 co-aggregates in FTD, and developing cryo-electron tomography for human brain tissue. An attending neuropathologist at the Hospital of the University of Pennsylvania, he has authored more than 250 publications, serves on multiple journal editorial boards, chairs the NIH CMND/CMN study section, and is deeply committed to mentoring the next generation of scientists and physician-scientists.
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