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[II-P02-2-01]Mortality Risk Factors in Potts Surgery for Advanced Pulmonary Hypertension: A Cohort Study

Mingjie Zhang, Xi Chen, Zhiyue Zhang, Yijun Chen, Zhuoming Xu (Shanghai Children's Medical Center, Shanghai Jiaotong University, School of Medicne)
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Potts Surgery、Mortality、Risk factors

AbstractBackground: The treatment of advanced pulmonary hypertension presents significant challenges. Potts surgery, both surgical and interventional, has increasingly become an effective treatment option for these patients at our center. However, the high mortality rate associated with the procedure limits its widespread adoption. This study aims to identify risk factors for mortality in a small cohort undergoing Potts surgery at our center.Methods: Between January 2023 and December 2024, a total of 24 Potts shunt were performed, including 11 percutaneous stent implantation(PCI) and 13 surgeries. Clinical parameters (e.g., CVP, PaO2, SaO2, TAPSE,PP/PS. Fluid balance) were compared between survivors and non-survivors across three post-operative days (POD 0, 1, and 2). ROC analysis was used to assess the predictive value of TAPSE and PP/PS.Results: In the PCI group, all the patients survived. In surgery group, survival rates were 80% for non-ECMO patients and 33% for ECMO patients. Factors such as RVEDVI over than 230 ml/m2(p = 0.016) and VMI over than 0.85 (p = 0.034) were significantly associated with death. ROC analysis revealed TAPSE over than 1.2cm (AUC = 0.972, sensitivity = 88%, specificity = 100%) and PP/PS over than 1.01 (AUC = 0.941, sensitivity = 100%, specificity = 88.2%) as strong predictors of survival.Conclusion: TAPSE and PP/PS were identified as reliable predictors of survival in Potts surgery, highlighting the preservation of right heart function and stable pulmonary artery pressure as key factors for the success of potts shunt in these patient.Keywo