講演情報
[III-PSY4-1]Update on Diagnosis and Management of Kawasaki Disease: Scientific Statement 2024 from AHA
○Pei-Ni Jone (Lurie Children’s Hospital, Northwestern University School of Medicine, Illinois)
キーワード：
Kawasaki Disease、coronary dilation、coronary aneurysm
Kawasaki Disease (KD), an acute self-limited febrile illness that primarily affects children < 5 years old, is the leading cause of acquired heart disease in the developed countries, with the potential of coronary artery dilation and coronary artery aneurysms in 25% of untreated patients. This update summarizes relevant clinical data published since the 2017 American Heart Association scientific statement on KD related to diagnosis, cardiac imaging in acute KD treatment, and long term management. Criteria defining North American patients at high risk for developing CAA who may benefit from more intensive initial treatment have been published. Advances in cardiovascular imaging have improved the ability to identify CA stenosis in KD patients, yet knowledge gaps still exist regarding optimal frequency of serial imaging and the best imaging modality to identify those at risk for inducible myocardial ischemia. Recent data has advanced the understanding of safety and dosing for several anti-inflammatory therapies in KD. New anticoagulation medication, myocardial infarction management, transition of health care for KD patients, and future directions in research for KD patients will be discussed.