講演情報
[III-PSY4-4]The Issues in the Long-Term and Adulthood of Kawasaki Disease
○Yiu-Fai Cheung (Paeditrics & Adolescent Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong / Paediatrics & Adolescent Medicine, Hong Kong Children’s Hospital, Hong Kong)
キーワード：
Kawasaki disease、cardiovascular、outcomes
Kawasaki disease (KD), an acute vasculitis that primarily affects young children, is the most common acquired paediatric cardiovascular disease in developed countries. It is almost six decades since its first description. While the sequelae of arterial inflammation in the acute illness are well documented, there exist potential long-term effects. Undoubtedly, persistent coronary artery lesions constitute the most significant morbidity and mortality after KD. There is a paucity of studies, however, on the long-term outcomes of children without documented coronary artery aneurysms, those with transient coronary artery ectasia, or those with some coronary aneurysms that have regressed. Nonetheless, even in these latter situations, there are data to suggest possible late functional alterations as characterized by endothelial dysfunction and arterial stiffening, and structural changes with increased intima media thickness. In this talk, the current data available on the long-term outcomes and prognosis of KD will be discussed.