[P1] Poster Session (1) / Corporate Exhibits

Flash TalksGenetics/Genome Science

[P1-01] Generation of a site-specific transcription factor blocker as a versatile TF inhibitor

*Hideo Negishi^1,2,3,4, Tatsuma Ban⁵, Mina Kurosawa¹, Shonrod Airisshu¹, Yusuke Wada¹, Tomoya Hayashi^1,2,4, Kaiwen Liu^1,2,4, Yoshitaka Shirasaki⁶, Temizoz Burcu^1,2,4, Kouji Kobiyama^1,2,4, Noriko Toyama-Sorimachi², Cevayir Coban^2,4,7, Tomohiko Tamura⁵, Tomio Iwasaki⁸, Ken J Ishii^1,2,4,9,10 (1. Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. (Japan), 2. International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. (Japan), 3. Laboratory of Immunology and Infection Control, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan. (Japan), 4. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), The University of Tokyo, Tokyo, Japan. (Japan), 5. Department of Immunology, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Yokohama, Japan. (Japan), 6. Division of Photonic Imaging, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan. (Japan), 7. Division of Malaria Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. (Japan), 8. Research and Development Group, Hitachi, Ltd., Ibaraki, Japan. (Japan), 9. Laboratory of Vaccine Science, Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan. (Japan), 10. Laboratory of Mockup Vaccine, Center for Vaccine and Adjuvant Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, Japan. (Japan))

キーワード：

transcription、site-specific blocker of TF (siTF)、IRF、type I IFN、pyrrole-imidazole polyamide (PIPA)

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