セッション詳細
[P2]Poster Session Core Time (偶数番号)
2025年3月18日(火) 18:00 〜 19:00
国際会議室 301(3F)
[P2-2]The effect of tissue hypoxia on the immune system in chronic inflammatory lung disease
*Atsushi Sasaki1,2,3, Masahiro Kiuchi2, Hiroyuki Yagyu2, Takahiro Arano2,3, Toshinori Nakayama4, Takuji Suzuki3, Kiyoshi Hirahara2 (1. Chiba University, Synergy Institute for Futuristic Mucosal Vaccine (Japan), 2. Department of Immunology, Graduate School of Medicine, Chiba University (Japan), 3. Department of Respirology, Graduate School of Medicine, Chiba University (Japan), 4. Chiba University (Japan))
[P2-4]A novel subpopulation of fibroblasts involved in the formation of inducible bronchus-associated lymphoid tissue
*Takahisa Hishiya1,2, Masahiro Kiuchi1, Seiji Ohtori2, Kiyoshi Hirahara1 (1. Department of Immunology, Chiba University (Japan), 2. Department of Orthopaedic Surgery, Chiba University (Japan))
[P2-6]電極チップを用いた次世代PBMC自動分取装置(高収率・高特異性)の開発
Development of an automatic PBMC/target cells separator with high performance (Recovery, Specificity), using state-of-the-art ES chip for the research into immunotherapy
*Hiromitsu Tazawa1, Yuki Furuya1, Osamu Kikuchi1,2, kazumi Sawakami4, Hidegi Tajima4, Manabu Mutou1,3 (1. Clinical Bioresource Center/Kyoto University Hospital (Japan), 2. Center for Cancer Immunotherapy and Immunobiology/CCII (Japan), 3. Clinical Oncology, Kyoto University Hospital (Japan), 4. Precision System Science Inc. (Japan))
[P2-8]Establishment of Large Scale Metabolomics Analysis Workflow
*Shohei Asami1, Tamotsu Kato1, Yumiko Nakanishi1, Ayumi Ito1, Hiroshi Ohno1 (1. RIKEN Center for Integrative Medical Sciences Laboratory for Intestinal Ecosystem (Japan))
[P2-10]Differential potency of memory T cells and memory B cells in older adults following COVID-19 mRNA vaccination
*Kohei Kometani1, Takaaki Yorimitsu1,2, Norihide Jo1,3, Yoko Hamazaki1,4,5 (1. Center for iPS Cell Research and Application (CiRA), Kyoto University (Japan), 2. Department of Human Health Sciences, Graduate School of Medicine, Kyoto University (Japan), 3. Alliance Laboratory for Advanced Medical Research, Graduate School of Medicine, Kyoto University (Japan), 4. Laboratory of Immunobiology, Graduate School of Medicine, Kyoto University (Japan), 5. Kyoto University Immunomonitoring Center (KIC) (Japan))
[P2-12]Adaptive Immune Receptor Gene Annotation for Mammalian Genomes
*Hao Zhou1,2, Kazutaka Katoh1,2, Daron M. Standley1,2 (1. Research Institute for Microbial Diseases, Osaka University (Japan), 2. Immunology Frontier Research Center, Osaka University (Japan))
[P2-14]The regulation of MHC-I antigen presentation pathway by NLRC5 and IRF1
*Tsutomu Tanaka1, Torsten B Meissner2,3, Saptha Vijayan4, Kyoung-Hee Lee2,3, Yuen-Joyce Liu2, Isaac Downs4, Tabasum Sidiq4, Jason Yeung4, Chi Zhang2, Peter van den Elsen5,6, Koichi S Kobayashi1,4 (1. The Institute for Vaccine Research and Development, Hokkaido University (Japan), 2. Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute (United States of America), 3. Department of Microbiology and Immunobiology, Division of Immunology, Harvard Medical School (United States of America), 4. Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center (United States of America), 5. Department of Immunohematology and Blood Transfusion, Leiden University Medical Center (Netherlands), 6. Department of Pathology, VU University Medical Center, Amsterdam (Netherlands))
[P2-16]Role of Nuclear transcription factor Y in NLRC5-mediated MHC class I gene expression
*Zufang Wu1, Yusuke Kasuga1,3, Tsutomu Tanaka1,3, Koichi Kobayashi1,2,3 (1. Department of Immunology, Hokkaido University Graduate School of Medicine (Japan), 2. Department of Microbial Pathogenesis and Immunology, Texas A&M University (United States of America), 3. Hokkaido University Institute for Vaccine Research and Development (Japan))
[P2-18]The crucial role of self and neoself discrimination by T cells in the pathogenesis of autoimmune diseases
*Shunsuke Mori1, Hisashi Arase1,2,3 (1. World Premier International Immunology Frontier Research Centre, Osaka University (Japan), 2. Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University (Japan), 3. Center for advanced modalities and DDS, Osaka University (Japan))
[P2-20]Residual Regnase-1-deficient CD4+ T cells, but not B cells, strongly enhance autoantibody production
*Hugo Angel Sato1, Kazuhiko Maeda1,2, Youdiil Ophinni1,3, Arthur Millius1,4, Shizuo Akira1,2,5 (1. Laboratory of Host Defense, WPI Immunology Frontier Research Center (WPI-IFReC), Osaka University, Osaka, Japan (Japan), 2. Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan (Japan), 3. Hakubi Center for Advanced Research, Department of Environmental Coexistence, Center for Southeast Asian Studies, Kyoto University (Japan), 4. Laboratory of Systems Immunology, WPI Immunology Frontier Research Center (WPI-IFReC), Osaka University, Osaka, Japan (Japan), 5. Center for Advanced Modalities and Drug Delivery System (CAMaD), Osaka University (Japan))
[P2-22]Establishment of methods for constructing and applying human artificial lymphoid tissue
*Yuka Kobayashi1, Takeshi Watanabe1, Hiroshi Kawamoto1 (1. Institute for Life and Medical Sciences, Kyoto University (Japan))
[P2-24]Identification of an endogenous mammalian antigen for iNKT cells
*Hayato Kasai1,2, Yuki Hosono1,2, Noriyuki Tomiyasu3, Yoshihiro Izumi3, Eri Ishikawa1,2, Masatomo Takahashi3, Takeshi Bamba4, Sho Yamasaki1,2,4 (1. Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University (Japan), 2. Laboratory of Molecular Immunology, Immunology Frontier Research Center (IFReC), Osaka University (Japan), 3. Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University (Japan), 4. Center for Infectious Disease Education and Research (CiDER), Osaka University (Japan))
[P2-26]Confidential
*Genta FURUYA1, Taiga KIMISHIMA1, Satoru NAGATOISHI2, Rae MAEDA3, Keishu TAKAHASHI1, Ryutaro TAMANO1, Tomoya OHNO1, Tomoki YOSHIHARA4, Kengo SASAKI1, Naoki MORITA1, Gao PENG1, Fabian EISENSTEIN7, Hirofumi KOSUGE2, Masumi SHIRAKAWA6, Hiroyuki ARAI8, Radostin DANEV7, Masahide KIKKAWA7, Shinsuke SANDO6, Naoshi DOHMAE5, Toshio HAKOSHIMA4, Yuki SUGIURA3, Kohei TSUMOTO2, Reiko SHINKURA1 (1. Laboratory of Immunology and Infection Control, Institute for Quantitative Biosciences, The University of Tokyo (Japan), 2. Department of Bioengineering, School of Engineering, The University of Tokyo (Japan), 3. Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine (Japan), 4. Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology (Japan), 5. Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science (Japan), 6. Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo (Japan), 7. Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo (Japan), 8. Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo (Japan))
[P2-28]Regnase-1 haploinsufficiency restricted SARS-CoV-2 pneumonia in mice, with reducing a neutrophil subset expressing interferon-stimulated genes
*Kotaro Tanaka1, Keiko Yasuda1,2, Junichi Aoki1,3, Shintaro Shichinohe4, Chikako Ono5,6,7, Alexis Vandenbon8, Daiya Ohara9, Yukiko Muramoto10, Songling Li11, Daisuke Motooka12, Hitomi Watanabe9, Keiji Hirota9, Gen Kondoh9, Takeshi Noda10, Daron M. Standley11, Yuzuru Ikehara13, Seiji Okada3, Tokiko Watanabe4,6,7, Yoshiharu Matsuura5,6,7, Osamu Takeuchi1 (1. Department of Medical Chemistry, Graduate School of Medicine, Kyoto University (Japan), 2. Department of Immunology, Nagoya City University Graduate School of Medical Sciences (Japan), 3. Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University (Japan), 4. Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University (Japan), 5. Laboratory of Virus Control, Research Institute for Microbial Diseases, Osaka University (Japan), 6. Center for Infectious Disease Education and Research, Osaka University (Japan), 7. Center for Advanced Modalities and DDS, Osaka University (Japan), 8. Laboratory of Tissue Homeostasis, Institute for Life and Medical Sciences, Kyoto University (Japan), 9. Laboratory of Integrative Biological Science, Institute for Life and Medical Sciences, Kyoto University (Japan), 10. Laboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University (Japan), 11. Department of Genome Informatics, Research Institute for Microbial Diseases, Osaka University (Japan), 12. NGS core facility, Bioinformatics Center, Research Institute for Microbial Diseases, Osaka University (Japan), 13. Department of Pathology, Graduate School of Medicine, Chiba University (Japan))
[P2-30]Single-cell RNA-seq and TCR receptor analysis of newly identified age-associated ThA cells
*Hiroyuki Teruya1, Toshiyuki Ushijima1, Manaka Goto1,2, Hideyuki Takahashi1, Takahiro Itamiya1,2, Hirofumi Shoda3, Haruka Tsuchiya1, Tomohisa Okamura1,2, Keishi Fujio1 (1. Department of Allergy and Rheumatology, Graduation School of Medicine, the University of Tokyo (Japan), 2. Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo (Japan), 3. Department of Rheumatology, Tokyo Medical University Hospital (Japan))
[P2-32]Therapeutic Potential of an Adjuvant-Containing Live-Attenuated AIDS Virus
*Maya Shofa1, Emiko Urano1, Tomotaka Okamura1, Yasuhiro Yasutomi1 (1. Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health, and Nutrition (Japan))
[P2-34]交叉反応性を向上させるワクチン抗原設計指針の確立および新規COVID-19ワクチン抗原の作出
Establishment of guidelines for designing useful vaccine antigens and production of new COVID-19 vaccine antigen
*Takuya Hemmi1, Takao Hashiguchi1 (1. Institute for Life and Medical Sciences, Kyoto University (Japan))
[P2-36]Development of A129 mouse as ADE model for dengue vaccine evaluation
*MYA MYAT NGWE TUN1,2,3, Yasuna Nakamura4, Chia Hsien Wu4, Jean Claude Balingit1, Ngan Thi Thanh Nguyen 1, Muhareva Raekiansyah1, Yuki Takamatsu2, Takeshi Urano3, Tsuyoshi Inoue4, Kouichi Morita1,2,3,5 (1. Department of Tropical Viral Vaccine Development, Institute of Tropical Medicine, Nagasaki University (Japan), 2. Department of Virology, Institute of Tropical Medicine, Nagasaki University (Japan), 3. Center for Vaccines and Therapeutic Antibodies for Emerging Infectious Diseases, Shimane University (Japan), 4. Department of Physiology of Visceral Function and Body Fluid, Graduate School of Biomedical Sciences, Nagasaki University (Japan), 5. Dejima Infectious Diseases Research Alliance, Nagasaki University (Japan))
[P2-38]Analysis of cellular stress responses and adjuvant effects by mRNA vaccines
*Yuji Kubota1, Ken J. Ishii2, Mutsuhiro Takekawa1 (1. Division of Cell Signaling and Molecular Medicine, Institute of Medical Science, The University of Tokyo (Japan), 2. Division of Vaccine Science, Institute of Medical Science, The University of Tokyo (Japan))
[P2-40]Evaluation of Clinical Trial Samples of Recipients of Inactivated Whole Virus Particle Influenza Vaccine Using Multi-Omics Analysis
*Yuichi Koshiishi1, Marumi Ohno2,3,4, Masafumi Endo5, Kayo Ibaraki5, Masashi Shingai1,2,3,6, Hiroshi Kida1,2,3,6 (1. Division of Vaccine Immunology, Hokkaido University (Japan), 2. Division of Biologics Development, Hokkaido University (Japan), 3. Institute for Vaccine Research and Development, Hokkaido University (Japan), 4. One Health research center, Hokkaido University (Japan), 5. KM Biologics Co. Ltd. (Japan), 6. International Collaboration Unit, Hokkaido University (Japan))
[P2-42]Evaluation of a condition to improve the immunogenicity of peptide-based vaccine
*Hiroki Hayashi1, Takashi Matsuzaki2, Hironori Nakagami1 (1. Department of Health Development and Medicine, Osaka University Graduate School of Medicine (Japan), 2. Department of DDS Pharmaceutical Development, Osaka University Graduate School of Medicine (Japan))
[P2-44]Evaluating the Potential of Inactivated Whole Virus Particle Influenza Vaccines to Elicit Broadly Protective Immunity
*Toshiki Sekiya1,2,3, Tomomi Kawakita2, Mamiko Kawahara1, Marumi Ohno1,2,4, Naoki Nomura1,2, Masashi Shingai1,2, Hiroshi Kida1,2 (1. International Institute for Zoonosis Control, Hokkaido University (Japan), 2. Institute for Vaccine Research and Development, Hokkaido Unviersity (Japan), 3. Deapartment of Microbiology and Immunology at Peter Doherty Institute, University of Melbourne (Australia), 4. One Health Research Center, Hokkaido University (Japan))
[P2-46]ARNAX is an adjuvant that enhances humoral and cellular immunity without systemic induction of IL-6 and IFN-α
*Tomomi Kawakita1, Toshiki Sekiya1,2, Naoki Nomura2, Marumi Ohno1,2, Chimuka Handabile1, Hiroshi Kida1,2, Misako Matsumoto2,3, Tsukasa Seya2,3, Masashi Shingai1,2 (1. Institute for Vaccine Research and Development, Hokkaido University (Japan), 2. International Institute for Zoonosis Control, Hokkaido University (Japan), 3. Nebuta Research Institute for Life Sciences, Aomori University (Japan))
[P2-48]Exploration of adjuvants for subunit vaccines to prevent West Nile virus infection
*Atsuko Inoue1,2, Yukari Itakura1, Shinji Saito1, Yasuko Orba1,3,4, Katsumi Maenaka1,2,3,5,6, Hirofumi Sawa1,3,4, Koshiro Tabata1 (1. Institute for Vaccine Research and Development, Hokkaido University (Japan), 2. Faculty of Pharmaceutical Science, Graduate School of Life Science, Hokkaido University (Japan), 3. International Institute for Zoonosis Control, Hokkaido University (Japan), 4. One Health Research Center, Hokkaido University (Japan), 5. Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University (Japan), 6. Global Station for Biosurfaces and Drug Discovery, Hokkaido University (Japan))
[P2-50]Antigenic characterization of A(H5N1) influenza candidate vaccine virus isolated in Hokkaido
*Shinji Saito1, Satoshi Osaki1, Koshiro Tabata1, Atsuko Inoue1, Yukari Itakura1, Gabriel Gonzalez1, Shinji Watanabe2, Hideki Asanuma2, Hideki Hasegawa2, Hirofumi Sawa1 (1. Institute for Vaccine Research and Development: HU-IVReD, Hokkaido University (Japan), 2. Research Center for Influenza and Respiratory Viruses, National institute of infectious diseases (Japan))
[P2-52]Challenges for the development of oral bait rabies vaccine
*Yukari Itakura1, Koshiro Tabata1, Shinji Saito1, Gabriel Gonzalez1, Hirofumi Sawa1,2 (1. IVReD, Hokkaido University (Japan), 2. International Institute for Zoonosis Control, Hokkaido University (Japan))
[P2-54]AI-Guided Rational Design of Next-Generation Dengue Fever Vaccine
*Sebastian Kapell1, Shara Bakytbek1, Farzaneh Valanezhad1, Ayako Hyuga1, Shin-Ichi Inoue1, Katsuyuki Yui1, Shusaku Mizukami1, Shinjiro Hamano1, Matheus Ferraz2, Ioannis Vardaxis2, Daiki Miura3, Daiki Mori3, Kazuhide Onoguchi3, Kaidre Bendjama1, Basu Dev Pandey1, Corazon Cerilla Buerano1, Trevor Clancy, Satoshi Kaneko1, Kouichi Morita1 (1. Nagasaki University (Japan), 2. NEC Oncoimmunity AS (Norway), 3. NEC Corporation (Japan))
[P2-56]Research on the development of paramyxovirus-based vaccines for henipaviruses
Yuying Wang1, Yuki Kitai1, Yukiko Akahori1, Hiroshi Katoh1, Hideko Watabe1, Taishi Onodera2, Daisuke Kuroda2, Ryutaro Kotaki2, Ryo Akihide2, Katsumi Maenaka4, Takao Hashiguchi3, Junki Maruyama5, Yoshimasa Takahashi2, *Makoto Takeda1 (1. The University of Tokyo (Japan), 2. National Institute of Infectious Diseases (Japan), 3. Kyoto University (Japan), 4. Hokkaido University (Japan), 5. University of Texas Medical Branch (United States of America))
[P2-58]非構造蛋白質NSsへ変異を導入したハートランドウイルスのバンダウイルス弱毒生ワクチンとしての有用性の評価
Evaluation of NSs gene modified recombinant heartland viruses as bandavirus vaccines
*Satoshi Taniguchi1,2, Shigeru Tajima2, Ken-Ichi Shibasaki2, Masayuki Saijo2, Masayuki Shimojima2, Chang-Kweng Lim2, Meng Ling Moi1, Hideki Ebihara2 (1. Graduate School of Medicine, the University of Tokyo (Japan), 2. National Institute of Infectious Diseases (Japan))
[P2-60]Survival of influenza viruses in environmental water
*Naoki Nomura1,2, Masashi Shingai1,2, Toshiki Sekiya1,2, Marumi Ohno1,2, Chimuka Handabile1,2, Tomomi Kawakita1,2, Yuichi Koshiishi1, Richard Obeng-Kyeremeh1, Mayako Kawahara1, Mihoko Ohashi1,2, Minori Haruta1,2, Yuki Shimoura1, Hiroshi Kida1,2 (1. Hokkaido University International Institute for Zoonosis Control (Japan), 2. Hokkaido University Institute for Vaccine Research and Development (Japan))
[P2-62]Evolutionary dynamics of heparan sulfate utilization by SARS-CoV-2
*Shuhei Higuchi1, Hisashi Arase1,2,3,4 (1. Center for Advanced Modalities and DDS, Osaka University (Japan), 2. Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University (Japan), 3. Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University (Japan), 4. Center for Infectious Dissease Education and Research, Osaka University (Japan))
[P2-64]Suppression of Sarbecovirus propagation by siRNA targeting the 5'UTR
*Chikako Ono1,2,3, Taro Shimizu4, Toshiro Hirai3,4, Tomoyuki Okuda6, Dita Pratama1,2, Kentaro Uemura1,2,3, Junki Hirano1,2, Kazuma Okada1,2,3, Shuhei Taguwa1,2,3, Yasuo Yoshioka1,4,5, Masanao Sato7, Yoshiharu Matsuura1,2,3 (1. Center for Infectious Disease Education and Research (Japan), 2. Research Institute for Microbial Diseases (Japan), 3. Center for Advanced Modalities and DDS (Japan), 4. BIKEN Innovative Vaccine Research Alliance Laboratories (Japan), 5. The Research Foundation for Microbial Diseases (Japan), 6. Faculty of Pharmacy, Meijo University (Japan), 7. Research Faculty of Agriculture, Hokkaido University (Japan))
[P2-66]Investigating the role of bats collected in Gabon in the ecology of emerging viruses.
*Christelle Pemba Mawonga1, Takaaki Kinoshita1, Ghislain W.E. Ella2, Chimene N. Nkogue2, Bernie Bouchedi2, Georgelin O. Nguema3, Hayato Ueda1, Yasuteru Sakurai1,4, Rokusuke Yoshikawa1,4, Haruka Abe1,5, Yuri Ushijima4,6, Murasaki Amano1, Etienne F. Akomo-Okoue2, Lilian B.M. Koumba2, Fred L.M. Nguelet2, Pierre P.M. Nguema2, Line N. Meyo1,7, Jiro Yasuda1,4,7 (1. Department of Emerging Infectious Diseases, National Research Center for the Control and Prevention of Infectious Diseases, Nagasaki University (Japan), 2. Institut de Recherche en Ecologie Tropicale (Gabon), 3. Centre de Recherches Médicales de Lambaréné (Gabon), 4. Department of Emerging Infectious Diseases, Institute of Tropical Medicine, Nagasaki University (Japan), 5. Vietnam Research Station, Institute of Tropical Medicine, Nagasaki University (Japan), 6. Division of Biomedical Science, Institute of Medicine, University of Tsukuba (Japan), 7. Graduate School of Biomedical Sciences, Nagasaki University (Japan))
[P2-68]Generation and evaluation of candidate vaccines against high pathogenicity avian influenza virus with pandemic potential
*Linh Bao Nguyen1, Norikazu Isoda1,2,3,4, Yik Lim Hew1, Dang Hoang Nguyen 5, Diep Thi Nguyen6, Long Van Nguyen6, Takahiro Hiono1,2,3,4, Yoshihiro Sakoda1,2,3,4 (1. Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Japan (Japan), 2. One Health Research Center, Hokkaido University, Japan (Japan), 3. International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Japan (Japan), 4. Hokkaido University Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Japan (Japan), 5. National Center for Veterinary Diagnosis, Vietnam (Viet Nam), 6. Department of Animal Health, Vietnam (Viet Nam))
[P2-70]Antigenic Variation Among Dengue Virus Genotypes Impacts Antibody-Mediated Neutralization and Antibody-Dependent Enhancement in Patients and Vaccinees
*Jean Claude Balingit1, Motoharu Abe2, Ryosuke Suzuki3, Dalouny Xayavong4, Mya Myat Ngwe Tun1,4,5, Mami Matsuda3, Yuki Takamatsu1,4, Corazon Buerano1, Kengo Sonoda2, Kouichi Morita1,4,6 (1. Department of Tropical Viral Vaccine Development, Institute of Tropical Medicine, Nagasaki University (Japan), 2. CMC Development Division, KM Biologics Co., Ltd. (Japan), 3. Department of Virology II, National Institute of Infectious Diseases (Japan), 4. Department of Virology, Institute of Tropical Medicine, Nagasaki University (Japan), 5. Center for Vaccine and Therapeutic Antibodies for Emerging Infectious Diseases, Shimane University (Japan), 6. DEJIMA Infectious Disease Research Alliance, Nagasaki University (Japan))
[P2-72]哺乳類・昆虫培養細胞内におけるフラビウイルス適応変異の同定とワクチン応用
Identification of Flaviviruses adaptive mutations during intra-host transmission in mammalian or mosquito cell line, and that application for vaccines
*Misao Himeno1, Ka Ching Wan1, Ryuichi Majima1, Satoshi Taniguchi1, Meng Ling Moi1 (1. Department of Developmental Medical Scienses, Faculty of Medicine, The University of Tokyo (Japan))
[P2-74]A mouse model for human typhoid fever
*Hoan T Pham1, Kohei Yamazaki2,3, Andreas J. Bäumler3, Toshio Kodama1, Hirotaka Hiyoshi1,3 (1. Institute of Tropical Medicine, Nagasaki University (Japan), 2. School of Veterinary Medicine, Kitasato University (Japan), 3. School of Medicine, University of California at Davis (United States of America))
[P2-76]Activity of WQ3034: A New Fluoroquinolone on DNA-Gyrase of Fluoroquinolone-Resistant Mycobacterium tuberculosis
*David Atomanyi Barnes1, Yuki Ouchi1, Sasini Jayaweera1, Pondpan Suwanthada1, Tamsin Barnes3, Jeewan Thapa1, Chie Nakajima1,2, Yasuhiko Suzuki1,2 (1. Division of Bioresources, Hokkaido University International Institute for Zoonosis Control, Sapporo (Japan), 2. Division of Research Support, Hokkaido University Institute for Vaccine Research and Development, Sapporo (Japan), 3. University of Queensland, School of Veterinary Medicine, Queensland (Australia))
[P2-78]Role of Exosomal Hydrolase Receptors in Entamoeba histolytica Pathogenesis
*Tomoyoshi Nozaki1, Herbert Santos1 (1. Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo (Japan))
[P2-80]Countermeasure for the next pandemic by the development of multi-metagenomics method
*Naoko Fujita1, Ryo Komorizono1, Yuki Furuse1 (1. Pandemic Preparedness, Infection and Advanced Research Center, The University of Tokyo (Japan))
[P2-82]Proteomic Identification of Potential Biomarkers Related to Helicobacter pylori Infection
*Sutthaorn Pothongsrisit1, Yoji Sagiya1, Hiromi Tsuru2, Chizu Tanikawa1, Koichi Matsuda1,2 (1. Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo (Japan), 2. Laboratory of Genome Technology, Human Genome Centre, Institute of Medical Science, University of Tokyo (Japan))
[P2-84]医療従事者における2023/2024インフルエンザワクチン接種前後抗体価評価
Evaluation of Antibody Titers Before and After Influenza Vaccination in Healthcare Workers During the 2023/2024 Season
*Yoshifumi Uwamino1 (1. Keio University School of Medicine (Japan))
[P2-86]Contribution of germline and somatic variation to neuromyelitis optica spectrum disorder
*Go Sato1,2,3, Tomohiro Yata1, Kotaro Ogawa1, Tatsuhiko Naito1,3, Ryuya Edahiro1,2,3, Kyuto Sonehara1,3,4, Ryunosuke Saiki5, Shinichi Namba1,3,4, Yuya Shirai1,3, Kenichi Yamamoto1, Seishi Ogawa5, Hideki Mochizuki1, Noriko Isobe6, Tatsusada Okuno1, Yukinori Okada1,2,3,4 (1. Osaka University Graduate School of Medicine (Japan), 2. Center for Advanced Modalities and DDS (CAMaD), Osaka University (Japan), 3. RIKEN Center for Integrative Medical Sciences (Japan), 4. Graduate School of Medicine, the University of Tokyo (Japan), 5. Graduate School of Medicine, Kyoto University (Japan), 6. Graduate School of Medical Sciences, Kyusyu University (Japan))
[P2-88]A multi-scale map of protein assemblies in the DNA damage response
*Anton Kratz1 (1. DEJIMA Infectious Disease Research Alliance (DIDA), Nagasaki University (Japan))
[P2-90]Elucidation of the genetic contribution of ancient hunter-gatherer Jomon in Japanese Populations
*Kenichi Yamamoto1, Shinichi Namba2,1, Kyuto Sonehara2,1, Ken Suzuki2, Niall P Cooke3,6, Koichi Matsuda2, Takashi Gakuhari4, Toshimasa Yamauchi2, Takashi Kadowaki5, Shigeki Nakagome6,4, Yukinori Okada1,2,7 (1. Osaka University (Japan), 2. The University of Tokyo (Japan), 3. Max Planck Institute (Germany), 4. Kanazawa University (Japan), 5. Toranomon Hospital (Japan), 6. Trinity college Dublin (Ireland), 7. RIKEN Institute (Japan))
[P2-92]Use Case for a Novel Benchtop Sequencer: Detecting Low-Frequency Mutations in Clonal Hematopoiesis
*Akinori Kanai1, Yukie Kashima1, Yutaka Suzuki1 (1. Graduate School of Frontier Sciences, The University of Tokyo (Japan))
[P2-94]Bioinformatics pipelines of expression and chromatin accessibility QTL to elucidate gene regulatory systems of diverse immune cell types
*RINTARO FUJIMOTO1,2, Hiroki Kitaoka1,3, Saya Hisano1,2,3, Ryuya Edahiro1,2, Go Sato1,2, Akari Suzuki1, Yukinori Okada1,2,3, Kazuhiko Yamamoto1 (1. RIKEN Center for Integrative Medical Sciences (Japan), 2. The University of Osaka (Japan), 3. The University of Tokyo (Japan))
[P2-96]Genetic and antigenic characterization of H5 high pathogenicity avian influenza viruses isolated in Hokkaido, Japan, 2023-2024 and 2024-2025
*Norikazu Isoda1,2,3,4, Takahiro Hiono1,2,3,4, Yik Lim Hew1, Daiki Kobayashi1, Yo Shimazu1, Nguyen Bao Linh1, Tatsuru Morita1, Yoshihiro Sakoda1,2,3,4 (1. Faculty of Veterinary Medicine, Hokkaido University (Japan), 2. One Health Research Center, Hokkaido University (Japan), 3. International Institute for Zoonosis Control, Hokkaido University (Japan), 4. Hokkaido University Institute for Vaccine Research and Cevelopment (Japan))
[P2-98]循環器疾患の重症化を予防するためのワクチン開発研究
Vaccine development research to prevent cardiovascular diseases
*Seitaro Nomura1, Issei Komuro1 (1. The University of Tokyo Hospital (Japan))
[P2-100]Control of RNase activity is crucial for single-cell RNA-Seq of granulocytes
*Daisuke Akiyama1,2, Yasuhiro Murakawa1,3 (1. Institute for the Advanced Study of Human Biology, Kyoto University (Japan), 2. Department of Hematology, Graduate School of Medicine, Kyoto University (Japan), 3. RIKEN-IFOM Joint Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama (Japan))
[P2-102]Spatial omics analysis reveals immune diversity and landscape
*Yukie Kashima1, Yutaka Suzuki1 (1. Graduate School of Frontier Sciences, The University of Tokyo (Japan))
[P2-104]次世代ヒトボカウイルスベクターワクチンの開発に関する基礎研究
Development of Novel HBoV vector vaccine
*Yuji Tsunekawa1, Jumpei Itho2, Takashi Okada1 (1. Institute of Medical Science, The University of Tokyo DMMG (Japan), 2. Institute of Medical Science, The University of Tokyo DSV (Japan))
[P2-106]ウイルス感染症の重症化抑制を目指した宿主側標的に対する創薬アプローチ
New drug Discovery approach targeting host factor to combat the exacerbation of viral infectious diseases
*芦田 仁己1
*Masami Ashida1, Saya Kuribayashi1, Yuki Hayashi1, Yoko Kamada1, Saori Nomura1, Jun Takasaki1, Kiyoshi Takayama1 (1. NB Health Laboratory (Japan))
*Masami Ashida1, Saya Kuribayashi1, Yuki Hayashi1, Yoko Kamada1, Saori Nomura1, Jun Takasaki1, Kiyoshi Takayama1 (1. NB Health Laboratory (Japan))
[P2-108]Mechanism of collision dependent mRNA degradation
*Satoshi Hashimoto1, Jiahuan ZENG1, Jennifer SAUERLAND2, Toshifumi INADA1 (1. Division of RNA and Gene Regulation The Institute of Medical Science, The University of Tokyo (Japan), 2. University of Heidelberg (Germany))
[P2-110]Confidential
*Shunji Suetaka1 (1. The University of Tokyo (Japan))
[P2-112]Shared Interferon-Dependent Pathway Signatures in Organoids Derived from Patients with COVID-19 and SARS-CoV-2 Infected Regional Airway Epithelial Culture
*Takanori Asakura1,2,3, Shuhei Azekawa3, Ho Namkoong4, Takashi Yokoyama4, Makoto Ishii5, Koichi Fukunaga3 (1. Department of Clinical Medicine (Laboratory of Bioregulatory Medicine), Kitasato University School of Pharmacy (Japan), 2. Department of Respiratory Medicine, Kitasato University Kitasato Institute Hospital (Japan), 3. Department of Medicine, Division of Pulmonary Medicine, Keio University School of Medicine (Japan), 4. Department of Infectious Disease, Keio University School of Medicine (Japan), 5. Department of Respiratory Medicine, Nagoya University Graduate School of Medicine (Japan))
[P2-114]慢性腎臓病マウスにおけるSARS-CoV-2感染への脆弱性と老化細胞との関連
Association of senescent cells with vulnerability to SARS-CoV-2 infection in chronic kidney disease mice
*Yoshimi Imawari1, Sae Aratani1, Hiroshi Ueki1, Yoshihiro Kawaoka1, Makoto Nakanishi1 (1. Institute of Medical Science, The University of Tokyo (Japan))
[P2-116]SARS-CoV-2 EG.5.1 スパイク蛋白質のクライオ電子顕微鏡解析
Cryo-EM analysis of SARS-CoV-2 EG.5.1 Spike protein
*Tomo Nomai1, Yuki Anraku1, Shunsuke Kita1, Hisano Yajima2, The G2P-Japan Consortium3, Takao Hashiguchi2, Takasuke Fukuhara4, Kei Sato5, Katsumi Maenaka1,6,7,8 (1. Faculty of Pharmaceutical Sciences, Hokkaido University (Japan), 2. Institute for Life And Medical Sciences, Kyoto University (Japan), 3. The G2P-Japan Consortium (Japan), 4. Faculty of Medicine, Hokkaido University (Japan), 5. The Institute of Medical Science, The University of Tokyo (Japan), 6. International Institute for Zoonosis Control, Hokkaido University (Japan), 7. Institute for Vaccine Research and Development, Hokkaido University (Japan), 8. Faculty of Pharmaceutical Sciences, Kyushu University (Japan))
[P2-118]Miniaturization of SARS-CoV-2 Neutralizing antibody for efficient cryo-EM analysis of a spike-antibody complex
*Taiyo Someya1, Yuki Anraku1, Shunsuke Kita1, Taishi Onodera2, Takashi Tadokoro3, Takao Hashiguchi4, Yoshimasa Takahashi2, Katsumi Maenaka1 (1. Faculty of Pharmaceutical science, Hokkaido University (Japan), 2. Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases (Japan), 3. Graduate School of Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Sanyo-Onoda city university (Japan), 4. Institute for Life and Medical Sciences, Kyoto University (Japan))
[P2-120]C57BL/6馴化SARS-CoV-2オミクロン株の性状解析
Characterization of C57BL/6 mouse-adapted SARS-CoV-2 omicron variants
*Saori Suzuki1,2, Rigel Suzuki 1,2, Shuhei Tsujino1, Lei Wang3, Hayato Ito1, Tomokazu Tamura1,2,4, Naganori Nao4,5, Keita Matsuno4,6, Shinya Tanaka3, Takasuke Fukuhara1,2,4,7,8 (1. Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University (Japan), 2. Institute for Vaccine Research and Development:IVReD, Hokkaido University (Japan), 3. Department of Cancer Pathology, Graduate School of Medicine, Hokkaido University (Japan), 4. One Health Research Center, Hokkaido University (Japan), 5. Division of International Research Promotion, International Institute for Zoonosis Control, Hokkaido University (Japan), 6. Division of Risk Analysis and Management, International Institute for Zoonosis Control, Hokkaido University (Japan), 7. Laboratory of Virus Control, Research Institute for Microbial Diseases, Osaka University (Japan), 8. Department of Virology, Graduate School of Medicine, Kyushu University (Japan))
[P2-122]遺伝子改変による感染症モデルマーモセット作出の試み
Attempts to create genetically modified marmoset as a model of infectious disease
*Wakako Kumita1, Natsuki Ooura1, Erika Sasaki1 (1. Central Institute for Experimental Medicine and Life Science (Japan))
[P2-124]Generating Mouse Models to Study OSKM Reprogramming and Immune Cell Epigenetics
*Sho Ohta1, Yasuhiro Yamada1 (1. Graduate School of Medicine, The University of Tokyo (Japan))
[P2-126]Modulating the immune cell fate with in vivo reprogramming technologies
*Yasuhiro Yamada1 (1. Graduate School of Medicine, The University of Tokyo (Japan))
[P2-128]セルフアジュバンティング乳がんペプチドワクチンの開発
Development of Self-Adjuvanting Anti-Breast-Cancer Peptide Vaccine
*Yoshiyuki Manabe1,2, Keita Ito1, Shino Ohshima3, Yoshie Kametani3, Kazunori Matsuura4, Koichi Fukase1,2,5 (1. Graduate school of science, Osaka University (Japan), 2. Forefront Research Center, Graduate School of Science, Osaka University (Japan), 3. School of Medicine, Tokai University (Japan), 4. Graduate School of Engineering, Tottori University (Japan), 5. Center for Advanced Modalities and DDS, Osaka University (Japan))
[P2-130]Synthesis of the High Functionality and Quality lipids for development of mRNA-based vaccines
*Shigeru Kawakami1, Makoto Matsumoto1, Geng Longjian1, Mariko Kamiya1, Kazuya Okami1, Yoshimasa Tanaka2 (1. Graduate School of Biomedical Sciences, Nagasaki University (Japan), 2. Center for Medical Innovation, Nagasaki University (Japan))
[P2-132]Finding patterns in multimodal omics data with multi-omics winnowing in R (mowR)
*Dorothy DeMore Ellis1, Jun Seita1 (1. RIKEN Center for Integrative Medical Sciences (Japan))
[P2-134]Development of the database interface for the multi-omics data in the human immune reference dataset
Jessica Severin1, Takahiro Nishino1, Hiroaki Hatano1, Yukinori Okada1, Kazuyoshi Ishigaki1, *Takeya Kasukawa1 (1. RIKEN Center for Integrative Medical Sciences (Japan))
[P2-136]AI-Driven Pattern Analysis of Drying Droplets of Mouse Serum for Diagnosing Malaria and Influenza Infections
*Anusuya Pal1, Rashmi Rekha Dash2, Ryuta Uraki3,4,5, Cevayir Coban2, Yoshihiro Kawaoka3,4,5,6, Miho Yanagisawa1 (1. Graduate School of Arts and Sciences, The University of Tokyo (Japan), 2. Division of Malaria Immunology, Department of Microbiology and Immunology, Institute of Medical Science (IMSUT), The University of Tokyo (Japan), 3. The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute (Japan), 4. Division of Virology, Institute of Medical Science, The University of Tokyo (Japan), 5. Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), The University of Tokyo (Japan), 6. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison (Japan))
[P2-138]Attitudes toward clinical trials and human challenge studies for vaccine development: A questionnaire survey of participants in a clinical trial in Japan
*Izen Ri1, Kintei Ko2, Masahiro Kitao1, Kyoko Mimura1, Yusuke Inoue3, Waki Toya4, Kaori Muto1 (1. Department of Public Policy, The Institute of Medical Science, The University of Tokyo (Japan), 2. Graduate School of Interdisciplinary Information Studies, The University of Tokyo (Japan), 3. Department of Healthcare Ethics, School of Public Health, Kyoto University (Japan), 4. Division of Bioethics and Medical Law, The Institute of Medical Science, The University of Tokyo (Japan))
[P2-140]Maximizing spleen-specific delivery of mRNA by lipid nanoparticle
*Yusuke Sato1, Yuichi Suzuki1, Mai Yakuwa1, Hideyoshi Harashima1 (1. Faculty of Pharmaceutical Sciences, Hokkaido University (Japan))
[P2-142]Tumor-specific immune activation mechanism induced by At-211
*Koki Mayusumi1, Kazuya Kabayama1,2,3, Kazuko Kaneda-Nakashima2,3, Kazuhiro Ooe2,3, Atsushi Toyoshima2,3, Koichi Fukase1,2,3 (1. Dept. of Chem., Grad. Sch. of Sci., Osaka Univ. (Japan), 2. FRC, Grad. Sch. of Sci., Osaka Univ. (Japan), 3. Inst. for Radiation Sciences, Osaka Univ. (Japan))
[P2-144]Dengue transmission dynamics and disease burden in Nha Trang, central Vietnam
Erik Koehne1, Michiko Toizumi1, Hien-Anh Thi Nguyen2, Lien Thuy Le3, Kim-Mai Huynh3, Hoang Huy Le2, Chihiro Iwasaki 1, Yutaro Yamagata1, Hung Thai Do 3, Kouichi Morita4, *Laymyint Yoshida1 (1. Institute of Tropical Medicine, Nagasaki University (Japan), 2. National Institute of Hygiene and Epidemiology (Viet Nam), 3. Pasteur Institute in Nha Trang (Viet Nam), 4. Dejima Infectious Disease Research Alliance, Nagasaki University (Japan))
[P2-146]Drug delivery system for accerallating mRNA therapeutics development
*Hiroki Tanaka1, Hidetaka Akita1 (1. Center for Advanced Modalities and DDS (CAMaD) (Japan))
[P2-148]ニードルフリー表皮内投与デバイスを用いた次世代型モックアップワクチンの開発
Development of a next-generation mock-up vaccine using an intradermal needle-free vaccination device
*Keiichi Motoyama1,2, Masahiro Ogura2, Riru Onigahara2, Honami Michiwaki2, Toru Taharabaru1,2, Taishi Higashi1,2, Shogo Misumi1,3, Naoki Kishimoto1,3, Hirotoshi Adachi4, Masahiko Kikuchi1,5 (1. Vaccine Development Research Center, Kumamoto University (Japan), 2. Graduate School of Pharmaceutical Sciences, Kumamoto University (Japan), 3. Depatment of Environmental and Molecular Health Sciences, Kumamoto University (Japan), 4. PassPort Technologies, Inc (United States of America), 5. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (Japan))
[P2-150]RNaseT2-deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells.
*Ryota Sato1, Kaiwen Liu1, Takuma Shibata1, Ryutaro Fukui1, Kensuke Miyake1 (1. Division of Innate Immunity, The Institute of Medical Science, The University of Tokyo (Japan))