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[F2-134]Trypanosoma cruziの細胞内寄生期に対する殺原虫化合物の優先順位付けのための革新的なアッセイ系の開発
High-throughput rate-of-kill assay, an innovative approach for prioritization of trypanocidal compounds against Trypanosoma cruzi amastigote stage

Mizuki Hayashishita1,2,3, Michele Lika Furuya1,2, Japheth Kibet Ng’etich4,5,6, Jean-Robert Ioset7, Takeshi Nara8, Takaya Sakura1,2,9, *Daniel Ken Inaoka1,2,9,10 (1. School of Tropical Medicine and Global Health, Nagasaki University (Japan), 2. Department of Infection Biochemistry, Institute of Tropical Medicine (NEKKEN), Nagasaki University (Japan), 3. Brazil Research Station, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University (Japan), 4. Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University (Japan), 5. Program for Nurturing Global Leaders in Tropical and Emerging Communicable Diseases, Graduate School of Biomedical Sciences, Nagasaki University (Japan), 6. Center for Traditional Medicine and Drug Research, Kenya Medical Research Institute (Kenya), 7. Drugs for Neglected Diseases Initiative (Switzerland), 8. Laboratory of Molecular Parasitology, Graduate School of Life Science and Technology, Iryo Sosei University (Japan), 9. Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University (Japan), 10. Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo (Japan))

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