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Mon. Mar 17, 2025

Tue. Mar 18, 2025

Wed. Mar 19, 2025

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An intellectual disability-related oligodendroglial secretory ligand, LGI3 organizes juxtaparanodal Kv1 channel clustering and function

The central nervous system (CNS) is made up of a huge number of neurons and glial cells that build up macro-scale neural networks via nano-scale synaptic contacts in a concerted manner, allowing for our recognition and behavior. This diverse and multilayered structure of the CNS has hindered our current understanding of the pathophysiology in the CNS. However, the evolution of anatomical technologies that enables nano-to-macroscale imaging in fixed or living neural tissues is paving the way to figure out CNS diseases. This symposium will invite four scientists, who have been tackling CNS diseases with conventional-to-advanced anatomical techniques such as confocal, super-resolution, and magnetic resonance imaging. They will discuss the molecular mechanisms for and therapeutic strategies against various neurodevelopmental or neurological disorders. This symposium will be collaborated with the 57th neuroanatomy satellite symposium, which has been held in the JAA annual meeting for many years. We hope that it will help not only accelerate our understanding of the CNS pathophysiology through evolving anatomical technologies, but also deepen our communications across different scientific societies.

He beats diseases who knows anatomy - The frontier of anatomical approaches against central nervous system diseases -

APPW2025

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[[OD]1S09m-1]An intellectual disability-related oligodendroglial secretory ligand, LGI3 organizes juxtaparanodal Kv1 channel clustering and function

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