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Uremic toxin-related systemic organ damage

Joint Session : The Japanese Society of Pathophysiology

The purpose of this symposium is to understand the impairment of internal biological systems caused by chronic kidney disease (CKD), which is estimated to affect 200 million individuals worldwide. To this end, speakers are called from various fields – anatomist, physiologist, pharmacologist, and experts in CKD treatment.    There is a definitive difference between severe damage to the kidney and that of other organs such as the heart, lung, and liver. That is, severe damage to organs other than the kidney results in death, while people with severe kidney damage can survive with the help of kidney replacement therapy (dialysis and kidney transplantation).    In such patients who have CKD (moderate to severe kidney damage), which is characterized by the accumulation of “uremic" substances, the internal biological system is impaired. Understanding this impairment can be useful from the point of view of aging science, for one of the important aspects of aging is loss of kidney function.

The impairment of internal biological systems caused by chronic kidney disease

APPW2025

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[[OD]2S13m-2]Uremic toxin-related systemic organ damage

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